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A Comprehensive Systematic Review: Advancements in Skin Cancer Classification and Segmentation Using the ISIC Dataset

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Computer Modeling in Engineering & Sciences 2024年第9期140卷 2131-2164页

作者： madiha Hameed Aneela Zameer Muhammad Asif Zahoor Raja Department of Computer Sciences Pakistan Institute of Engineering and Applied SciencesNilore50700Islamabad Future Technology Research Center National Yunlin University of Science and TechnologyDouliou64002TaiwanChina Directorate of IT Services University of GujratGujrat50700Pakistan

The International Skin Imaging Collaboration(ISIC)datasets are pivotal resources for researchers in machine learning for medical image analysis,especially in skin cancer *** datasets contain tens of thousands of dermoscopic photographs,each accompanied by gold-standard lesion diagnosis *** challenges associated with ISIC datasets have spurred significant advancements,with research papers reporting metrics surpassing those of human *** cancers are categorized into melanoma and non-melanoma types,with melanoma posing a greater threat due to its rapid potential for metastasis if left *** paper aims to address challenges in skin cancer detection via visual inspection and manual examination of skin lesion images,processes historically known for their *** notable advancements in machine learning and deep learning models,persistent challenges remain,largely due to the intricate nature of skin lesion *** review research on convolutional neural networks(CNNs)in skin cancer classification and segmentation,identifying issues like data duplication and augmentation *** explore the efficacy of Vision Transformers(ViTs)in overcoming these challenges within ISIC dataset *** leverage their capabilities to capture both global and local relationships within images,reducing data duplication and enhancing model ***,ViTs alleviate augmentation issues by effectively leveraging original *** a thorough examination of ViT-based methodologies,we illustrate their pivotal role in enhancing ISIC image classification and *** study offers valuable insights for researchers and practitioners looking to utilize ViTs for improved analysis of dermatological ***,this paper emphasizes the crucial role of mathematical and computational modeling processes in advancing skin cancer detection methodologies,highlighting their significance in improving algorithmic

关键词： Medical image skin cancer classification skin cancer segmentation international skin imaging collaboration convolutional neural network deep learning

Comprehensive Understanding of Immune Cells in The Pathogenesis of Non-alcoholic Fatty Liver Disease

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生物化学与生物物理进展 2024年第9期51卷 2082-2100页

作者： OUYANG Fei-Fan RASHEED madiha LI Bo DENG Yu-Lin Advanced Research Institute of Multidisciplinary Science Beijing Institute of TechnologyZhuhai 519088China Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals School of Life ScienceBeijing Institute of TechnologyBeijing 100081China Advanced Research Institute of Multidisciplinary Science Beijing Institute of TechnologyBeijing 100081China

Non-alcoholic fatty liver disease(NAFLD)is the most common chronic liver disease,defined by several phases,ranging from benign fat accumulation to non-alcoholic steatohepatitis(NASH),which can lead to liver cancer and *** NAFLD is a disease of disordered metabolism,it also involves several immune cell-mediated inflammatory processes,either promoting and/or suppressing hepatocyte inflammation through the secretion of pro-inflammatory and/or anti-inflammatory factors to influence the NAFLD ***,the underlying disease mechanism and the role of immune cells in NAFLD are still under investigation,leaving many open-ended *** this review,we presented the recent concepts about the interplay of immune cells in the onset and pathogenesis of *** also highlighted the specific non-immune cells exhibiting immunological properties of therapeutic significance in *** hope that this review will help guide the development of future NAFLD therapeutics.

关键词： non-alcoholic fatty liver disease metabolically associated fatty liver disease(MAFLD) T cells myeloid cells mesenchymal stem cells

Electrochemical anodization of cast titanium alloys in oxalic acid for biomedical applications

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Frontiers of Chemical Science and Engineering 2024年第1期18卷 13-24页

作者： Engie M.Safwat Soha A.Abdel-Gawad madiha A.Shoeib Shimaa El-Hadad Restorative and Dental Materials Department National Research CentreGiza 12622Egypt Chemistry Department Faculty of ScienceCairo UniversityGiza 12613Egypt Central Metallurgical Research and Development Institute Helwan 11421Egypt

Titanium and its alloys have numerous biomedical applications thanks to the composition and morphology of their oxide *** this study,the colorful oxide films were formed by anodizing cast Ti-6Al-4V and Ti-6Al-7Nb alloys in a 10%oxalic acid solution for 30 s at different voltages(20–80 V)of a direct current power *** force microscopy was used as an accurate tool to measure the surface roughness of thin films on the nanometer *** electron microscopy and X-ray diffraction were performed to analyze surface morphology and phase *** to the results,the produced titanium oxide layer showed high surface roughness,which increased with increasing anodizing *** impact of anodizing voltages on the color and roughness of anodized layers was *** corrosion resistance of the anodized samples was studied in simulated body fluid at pH 7.4 and a temperature of 37℃ utilizing electrochemical impedance spectroscopy and the potentiodynamic polarization *** anodized samples for both alloys at 40 V were at the optimal voltage,leading to a TiO_(2) layer formation with the best compromise between oxide thickness and corrosion ***,findings showed that TiO_(2) films produced on Ti-6Al-7Nb alloys had superior surface roughness properties compared to those of Ti-6Al-4V alloys,making them more appropriate for orthopedic *** the obtained data and the fruitful discussion,it was found that the utilized procedure is simple,low-cost,and ***,anodization in 10%oxalic acid proved a viable alternative for the surface finishing of titanium alloys for biomedical applications.

关键词： DC anodization Ti-6Al-4V alloy Ti-6Al-7Nballoy oxidefilm corrosion

Trehalose:A sugar molecule involved in temperature stress management in plants

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The Crop Journal 2024年第1期12卷 1-16页

作者： Ali Raza Savita Bhardwaj Md Atikur Rahman Pedro García-Caparrós madiha Habib Faisal Saeed Sidra Charagh Christine H.Foyer Kadambot H.M.Siddique Rajeev K.Varshney College of Agriculture Fujian Agriculture and Forestry University(FAFU)Fuzhou 350002FujianChina Department of Botany School of Bioengineering and BiosciencesLovely Professional UniversityPhagwara 144411India Department of Botany MCM DAV CollegeKangraHimachal Pradesh 176001India Grassland and Forage Division National Institute of Animal ScienceRural Development AdministrationCheonan 31000Republic of Korea Agronomy Department of Superior School Engineering University of AlmeríaAlmeríaSpain National Institute for Genomics and Advanced Biotechnology National Agricultural Research CentrePark Rd.Islamabad 45500Pakistan Agriculture Health and Environment DepartmentNatural Resources InstituteFaculty of Engineering&ScienceUniversity of GreenwichKent ME44TBUK State Key Laboratory of Rice Biology China National Rice Research InstituteChinese Academy of Agricultural SciencesHangzhouZhejiangChina School of Biosciences College of Life and Environmental SciencesUniversity of BirminghamEdgbaston B152TTUK The UWA Institute of Agriculture The University of Western AustraliaCrawleyPerth 6009Australia WA State Agricultural Biotechnology Centre Centre for Crop and Food InnovationFood Futures InstituteMurdoch UniversityMurdochWA 6150Australia

Trehalose(Tre)is a non-reducing disaccharide found in many species,including bacteria,fungi,invertebrates,yeast,and even plants,where it acts as an osmoprotectant,energy source,or protein/membrane *** relatively small amounts in plants,Tre concentrations increase following exposure to abiotic ***-6-phosphate,a precursor of Tre,has regulatory functions in sugar metabolism,crop production,and stress *** the various abiotic stresses,temperature extremes(heat or cold stress)are anticipated to impact crop production worldwide due to ongoing climate *** small amounts of Tre can mitigate negative physiological,metabolic,and molecular responses triggered by temperature *** also interacts with other sugars,osmoprotectants,amino acids,and phytohormones to regulate metabolic reprogramming that underpins temperature stress *** plants expressing Tre-synthesis genes accumulate Tre and show improved stress ***-wide studies of Tre-encoding genes suggest roles in plant growth,development,and stress *** review discusses the functions of Tre in mitigating temperature stress—highlighting genetic engineering approaches to modify Tre metabolism,crosstalk,and interactions with other molecules—and in-silico approaches for identifying novel Tre-encoding genes in diverse plant *** consider how this knowledge can be used to develop temperature-resilient crops essential for sustainable agriculture.

关键词： Abiotic stress Gene expression Genetic engineering Osmolyte Trehalose-6-phosphate

Influence of anodization conditions on deposition of Hydroxyapatite on α/β Ti alloys for Osseointegration: Atomic Force Microscopy Analysis

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Transactions of Nonferrous Metals Society of China 2024年

作者： Rania E.Hammam Engie M.Safwat Soha A.Abdel-Gawad madiha Shoeib Shimaa El-Hadad Faculty of Engineering， Modern University for Technology and Information (MTI) Restorative and Dental Materials Department， National Research Centre Giza Chemistry Department， Faculty of Science， Cairo University Central Metallurgical Research and Development Institute P.O.87

Integrating titanium-based implants with the surrounding bone tissue remains challenging. This study aims to explore the impact of different anodization voltages （20-80V） on the surface topography of two-phase （α/β） Ti alloys and to produce TiO2films with enhanced bone formation abilities. Scanning electron microscopy coupled with energy dispersive spectroscopy （SEM-EDS） and atomic force microscopy （AFM） were applied to investigate the morphological， chemical， and surface topography of the prepared alloys and to confirm the growth of hydroxyapatite （HA） on their surfaces. Results disclosed that the surface roughness of TiO2films formed on Ti-6Al-7Nb alloys was superior to that of Ti–6Al–4V alloys. Ti-6Al-7Nb alloy anodized at 80 V had the highest yields of HA after immersion in SBF with enhanced HA surface coverage. The developed HA layer had a mean thickness of 128.38 ± 18.13 μm， suggesting its potential use as an orthopedic implantable material due to its promising bone integration and， hence， remarkable stability inside the human body.

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免疫细胞在非酒精性脂肪肝发病机制中的作用(英文)

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生物化学与生物物理进展 2024年

作者：欧阳飞凡 madiha Rasheed 李博邓玉林北京理工大学生命学院生物医药分离与分析北京市重点实验室北京理工大学前沿交叉科学研究院

非酒精性脂肪肝（NAFLD）是最常见的慢性肝病，是从脂肪堆积到变性炎症，并出现非酒精性脂肪性肝炎（NASH），直至引发肝纤维化、肝硬化甚至肝癌的一系列过程。非酒精性脂肪目前已经是全球感染人群占比最大的肝病且发病率逐年上升。非... 详细信息

非酒精性脂肪肝（NAFLD）是最常见的慢性肝病，是从脂肪堆积到变性炎症，并出现非酒精性脂肪性肝炎（NASH），直至引发肝纤维化、肝硬化甚至肝癌的一系列过程。非酒精性脂肪目前已经是全球感染人群占比最大的肝病且发病率逐年上升。非酒精性脂肪肝是一种新陈代谢紊乱的疾病，但它也涉及多种免疫细胞介导的炎症过程，通过分泌促炎和/或抗炎因子来促进和/或抑制肝细胞炎症，从而影响非酒精性脂肪肝的进程。然而，其潜在的疾病机制及其在免疫细胞中的作用仍在研究之中，留下了许多悬而未决的问题。因此，在这篇综述中，我们介绍了免疫细胞在非酒精性脂肪肝的发病和致病过程中相互作用的最新概念。我们还重点介绍了在非酒精性脂肪肝中表现出具有治疗意义的免疫学特性的特定非免疫细胞，以便更好地了解表现出治疗特性的免疫/非免疫细胞的作用机制，从而在未来设计出治疗非酒精性脂肪肝的创新性和更具特异性的药物。

关键词：非酒精性脂肪肝病代谢相关性脂肪肝病(MAFLD) T细胞髓样细胞间充质干细胞

Squamous Cell Carcinoma of the Middle Ear: Case Report and Literature Review

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Journal of Cancer Therapy 2024年第9期15卷 303-310页

作者： Mariam Harrak Khouloud Ziani madiha Chelakhi Othmane Saqri Nabila Sellal Mohamed El Hfid Department of Radiotherapy University Hospital Mohamed VI of Tangier Tangier Morocco

Malignant tumors originating from the middle ear are rare. The literature identifies chronic inflammation and Human Papillomavirus (HPV) infection as the most common risk factors. A CT scan to assess bony invasion and an MRI to evaluate soft tissue involvement, depth of invasion, and perineural invasion, followed by a biopsy, are indispensable for diagnosis and treatment. There is no standard treatment for squamous cell carcinoma of the middle ear, however, most reported cases are treated with surgical resection followed by postoperative radiotherapy. Given the challenges of achieving complete surgical excision, radiotherapy plays a crucial role in controlling middle ear cancers, as demonstrated in our case. We present a case of squamous cell carcinoma of the middle ear in a 63-year-old female with a history of chronic suppurative otitis media. The patient underwent a right subtotal petrosectomy without lymph node dissection followed by concurrent chemoradiotherapy. At the one-year follow visit, no recurrence or metastasis was detected.

关键词： Chronic Suppurative Otitis The Middle Ear Squamous Cell Carcinoma Surgery Radiotherapy

Numerical Analysis of Unsteady Magneto-Biphase Williamson Fluid Flow with Time Dependent Magnetic Field

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Communications in Theoretical Physics 2019年第2期71卷 143-151页

作者： madiha Bibi M.Y.Malik A.Zeeshan Department of Mathematics College of Sciences P.O.Box 9004 King Khalid University Department of Mathematics Quaid-I-Azam University Department of Mathematics and Statistics Faculty of Basic and Applied Sciences International Islamic University

Numerical investigation of the dusty Williamson fluid with the dependency of time has been done in current disquisition. The flow of multiphase liquid/particle suspension saturating the medium is caused by stretching of porous surface. The influence of magnetic field and heat generation/absorption is observed. It is assumed that particle has a spherical shape and distributed uniformly in fluid matrix. The unsteady two-dimensional problems are modeled for both fluid and particle phase using conservation of mass, momentum and heat transfer. The finalized model generates the non-dimensioned parameters, namely Weissenberg number, unsteadiness parameter, magnetic parameter,heat generation/absorption parameter, Prandtl number, fluid particle interaction parameter, and mass concentration parameters. The numerical solution is obtained. Locality of skin friction and Nusselt number is deliberately focused to help of tables and graphs. While inferencing the current article it is clearly observed that increment of Williamson parameter, unsteadiness parameter, magnetic parameter, volume fraction parameter, and mass concentration parameter reduces the velocity profile of fluid and solid particles as well. And increment of Prandtl number, unsteadiness parameter,volume fraction parameter, and mass concentration parameter reduces the temperature profile of fluid and solid particles as well.

关键词： unsteady flow multiphase Williamson fluid variable magnetic field permeable wall heat source/sink

Study of the ornamentation of Bhong Mosque for the survival of decorative patterns in Islamic architecture

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Frontiers of Architectural Research 2018年第2期7卷 122-134页

作者： madiha Ahmad Khuram Rashid Neelum Naz Department of Architecture University of Lahore Pakistan Department of Architectural Engineeringand Design University of Engineering and Technology Lahore Pakistan Department of Architecture University of Engineering and Technology Lahore Pakistan

Islamic architecture is rich in decorative patterns. Mosques were constructed in the past as simple buildings for offering prayers five times a day. However, in subsequent periods, various features of ornamentation in the form of geometry and arabesque were applied to the surfaces of mosques to portray paradise symbolically. This research applied descriptive approaches to examine the surviving patterns of the Aga-Khan-awarded Bhong Mosque and categorized these patterns as geometric and arabesque. This categorization was achieved by photography, use of software for patterns, and conducting interviews with local elderly persons in the region. The geometric patterns were simple 6- and 8-point star patterns. Several of the eartiest examples of rosette petals exhibited 8- and 10-point star patterns and were categorized by incorporating the geometric style and location of mosques. This research investigated different arabesque categories and inscription types and determined the aesthetic and cultural reasons for their placement on various surfaces. Frescoes had different types of flowers, fruits, and leaves, and a few of them belonged to the local region.

关键词： Bhong Mosque Decorative patterns Categorization Geometry Arabesque