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Benefit in physical function and quality of life to nonsurgical treatment of varicose veins: Pilot study

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World Journal of Clinical Cases 2024年第3期12卷 517-524页

作者： Gwon-Min Kim BoKun Kim Minwoo Jang Jong-Hwan Park Miju Bae Chung Won Lee Jong Won Kim up Huh Medical Research Institute Pusan National University School of MedicineYangsan 50612South Korea Future Convergence Research Institute Changwon National UniversityChangwon 51140South Korea Department of Convergence Medical Science School of MedicinePusan National UniversityYangsan 50612South Korea Health Convergence Medicine Laboratory Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Thoracic and Cardiovascular Surgery Pusan National University School of MedicineBiomedical Research InstitutePusan National University HospitalBusan 49241South Korea

BACKGROUND Studies on varicose veins have focused its effects on physical function;however,whether nonsurgical treatments alter muscle oxygenation or physical function remains ***,the differences in such functions between individuals with varicose veins and healthy individuals remain *** To investigate changes in physical function and the quality of life(QOL)following nonsurgical treatment of patients with varicose veins and determine the changes in their muscle oxygenation during *** We enrolled 37 participants(those with varicose veins,n=17;healthy individuals,n=20).We performed the following measurements pre-and post-nonsurgical treatment in the varicose vein patients and healthy individuals:Calf muscle oxygenation during the two-minute step test,open eyes one-leg stance,30 s sit-to-stand test,visual analog scale(VAS)for pain,Pittsburgh sleep quality index,physical activity assessment,and QOL *** Varicose veins patients and healthy individuals differ in most variables(physical function,sleep quality,and QOL).Varicose veins patients showed significant differences between pre-and post-nonsurgical treatment—results in the 30 sit-to-stand test[14.41(2.45)to 16.35(4.11),P=0.018],two-minute step test[162.29(25.98)to 170.65(23.80),P=0.037],VAS for pain[5.35(1.90)to 3.88(1.73),P=0.004],and QOL[39.34(19.98)to 26.69(17.02),P=0.005];however,no significant difference was observed for muscle *** Nonsurgical treatment improved lower extremity function and QOL in varicose veins patients,bringing their condition close to that of healthy *** studies should include patients with severe varicose veins requiring surgery to confirm our findings.

关键词： Varicose vein Nonsurgical treatment Physical function Quality of life Near infrared spectroscopy

Prevalence and risk factors for impaired renal function among Asian patients with nonalcoholic fatty liver disease

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 241-248页

作者： Chao Sun George Boon-Bee Goh Wan-Cheng Chow Wah-Kheong Chan Grace Lai-Hung Wong Wai-Kay Seto Yi-Hsiang Huang Han-Chieh Lin I-Cheng Lee Hye Won Lee Seung up Kim Vincent Wai-Sun Wong Jian-Gao Fan Center for Fatty Liver Disease Department of GastroenterologyXinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai Key Lab of Pediatric Gastroenterology and NutritionShanghai 200092China Department of Gastroenterology&Hepatology Singapore General HospitalSingaporeSingapore Gastroenterology and Hepatology Unit Department of MedicineFaculty of MedicineUniversity of MalayaKuala LumpurMalaysia Department of Medicine and Therapeutics and State Key Laboratory of Digestive Disease The Chinese University of Hong KongHong KongChina Department of Medicine The University of Hong KongHong KongChina Institute of Clinical Medicine National Yang Ming Chiao Tung University School of MedicineTaipeiTaiwanChina Division of Gastroenterology and Hepatology Taipei Veterans General HospitalTaipeiTaiwanChina Faculty of Medicine National Yang Ming Chiao Tung University School of MedicineTaipeiTaiwanChina Department of Internal Medicine Yonsei University College of MedicineSeoulKorea

Background:Nonalcoholic fatty liver disease(NAFLD)is associated with impaired renal function,and both diseases often occur alongside other metabolic ***,the prevalence and risk factors for impaired renal function in patients with NAFLD remain *** objective of this study was to identify the prevalence and risk factors for renal impairment in NAFLD ***:All adults aged 18-70 years with ultrasound-diagnosed NAFLD and transient elastography examination from eight Asian centers were enrolled in this prospective *** fibrosis and cirrhosis were assessed by FibroScan-aspartate aminotransferase(FAST),Agile 3+and Agile 4 *** renal function and chronic kidney disease(CKD)were defined by an estimated glomerular filtration rate(eGFR)with value of<90 mL/min/1.73 m^(2) and<60 mL/min/1.73 m^(2),respectively,as estimated by the CKD-Epidemiology Collaboration(CKD-EPI)***:Among 529 included NAFLD patients,the prevalence rates of impaired renal function and CKD were 37.4%and 4.9%,*** multivariate analysis,a moderate-high risk of advanced liver fibrosis and cirrhosis according to Agile 3+and Agile 4 scores were independent risk factors for CKD(P<0.05).Furthermore,increased fasting plasma glucose(FPG)and blood pressure were significantly associated with impaired renal function after controlling for the other components of metabolic syndrome(P<0.05).Compared with patients with normoglycemia,those with prediabetes[FPG≥5.6 mmol/L or hemoglobin A1c(HbA1c)≥5.7%]were more likely to have impaired renal function(P<0.05).Conclusions:Agile 3+and Agile 4 are reliable for identifying NAFLD patients with high risk of *** glycemic control in the prediabetic stage might have a potential renoprotective role in these patients.

关键词： Nonalcoholic fatty liver disease Impaired renal function Agile 3+ Agile 4 Metabolic syndrome

乙炔前驱体对含银的类金刚石碳薄膜结构和抗菌性能的影响

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生物医学工程研究 2024年第1期43卷 76-80页

作者：付涛林小雯李欣培 Hasan mb 西安博恩生物科技有限公司西安710077 西安交通大学生命科学与技术学院生物医学信息工程教育部重点实验室西安710049

本研究在磁控溅射镀膜气氛中添加乙炔,制备了含银的氢化类金刚石碳(DLC-Ag)薄膜,以抑制薄膜表面银析出。通过扫描电镜、电子能谱、色差和显微硬度测量、琼脂平板计数抗菌实验,考察其对膜层抗菌性能的影响。结果表明,乙炔流量升高时,薄... 详细信息

本研究在磁控溅射镀膜气氛中添加乙炔,制备了含银的氢化类金刚石碳(DLC-Ag)薄膜,以抑制薄膜表面银析出。通过扫描电镜、电子能谱、色差和显微硬度测量、琼脂平板计数抗菌实验,考察其对膜层抗菌性能的影响。结果表明,乙炔流量升高时,薄膜表面的银析出减少,黑度增加,硬度降低;银含量最低的试样(0.8 at%)也对大肠杆菌表现出良好的抗菌性能。

关键词：类金刚石碳银磁控溅射薄膜抗菌

Late Quaternary Paleoclimatic Change in the Ulleung Basin,East Sea,Korea

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Acta Geologica Sinica(English Edition) 2017年第1期91卷 263-269页

作者： Young-Suk BAK Young-up LEE The Earth and Environmental System Research Center Chonbuk National University Jeonju 54896 South Korea

Paleoclimatic changes in the late Quaternary sediments deposited in the East Sea were analyzed by studying diatoms. A total of 95 species belonging to 47 genera were identified from the Core02GHP-02 of the Ulleung Basin in the East Sea, Korea. In the Core 02GHP-02, U-Oki（169–181 cm; 9.3 ka）, AT（464–465.5 cm; 22 ka） and U–Ym（556–559 cm; 33 ka） tephra layers were recognized. The chronological divisions of 02GHP-02 may be correlated with the climatic changes from the glacial interval（730–620 cm; MIS3）, to interstadial（620–500 cm; MIS3）, to the last glacial maximum（500–390 cm; MIS 2）, to the deglaciation（390–290 cm; MIS 2）, to the late glacial（290–190 cm; MIS 1）, and to the Holocene（190–10 cm; MIS 1）. It is speculated that diatoms were rarely found during the glacial interval when the 02GHP-02 core was deposited; during the interstadial（MIS 3） and deglaciation, a mixture of warm-water and cold-water species were found. In particular, Fragilariopsis doliolus seems to have appeared in the East Sea after 8 ka BP. In the lower layers of the Holocene deposits, cold-water species such as Neodenticula seminae were frequently found, while in the upper layers, warm-water species such as Hemidiscus cuneiformis were found in relatively large abundance. Therefore, the findings indicate that the climate became warmer during the transition from the lower layer to the upper layer of the Holocene deposits.

关键词： diatoms paleoclimatic change late Quaternary glacial interval MIS

Transient elastography in chronic hepatitis B: An Asian perspective

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World Journal of Gastroenterology 2010年第41期16卷 5173-5180页

作者： Seung up Kim Kwang-Hyub Han Sang Hoon Ahn Department of Internal Medicine Institute of Gastroenterology Yonsei University College of Medicine Seoul 120-752 South Korea Liver Cirrhosis Clinical Research Center Seoul 120-752 South Korea Brain Korea 21 Project for Medical Science Seoul 120-752 South Kore

Transient elastography (TE) is a new non-invasive tool for assessing liver stiffness, which is correlated with the histologic stage of liver fibrosis. Many studies have reported a good accuracy of TE in predicting signif icant fibrosis and an optimal accuracy in predicting cirrhosis. Furthermore, the potential role of TE in screening the general population has also been proven. TE thus helps physicians to decide treatment strategies, predict prog-nosis, and monitor disease progression in patients with chronic liver disease and to screen the general popula-tion to identify high risk patients with potential liver disease. However, most data on the clinical roles of TE have been gathered in European patients with chronic hepatitis C (CHC), because TE was first developed in France. Accordingly, much data on the usefulness of TE in patients with CHC has accumulated. Recently, however, vigorous efforts have been made to apply TEto patients with chronic hepatitis B (CHB), and TE has also proved to have acceptable accuracy in diagnosing liver fibrosis and cirrhosis in these patients. Thus, we focused on TE in the Asian population with CHB in comparison with the European population with CHC and found that the diagnostic performance and cutoff values were different between the 2 populations possibly as a result of several different confounders between Asian and European populations (the etiology of chronic liver disease, histologic features, major fluctuation in alanine aminotransferase levels, and the prevalence of high body mass index and metabolic syndrome). Therefore, further studies tailored to the Asian population with CHB should be performed before the widespread application of TE in Asian populations with CHB.

关键词： Asia Chronic hepatitis B Fibroscan Hepatitis B virus Liver stiffness measurement Transient elas-tography

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《江苏省对口支援新疆建设志》编纂始末

江苏地方志 2024年第1期 93-95页

作者：江苏援疆志编辑室江苏省地方志办公室江苏南京210004

寒来暑往,历经六载,在江苏省委、省政府高度重视和省政府办公厅指导推动下,在省各有关部门、相关设区市政府,省对口支援新疆伊犁州、克州前方指挥部和各前方工作组等大力支持下,在具体参与编纂工作的200余位同志共同努力下,由省地方志... 详细信息

寒来暑往,历经六载,在江苏省委、省政府高度重视和省政府办公厅指导推动下,在省各有关部门、相关设区市政府,省对口支援新疆伊犁州、克州前方指挥部和各前方工作组等大力支持下,在具体参与编纂工作的200余位同志共同努力下,由省地方志办公室组织编纂的《江苏省对口支援新疆建设志》终于付梓。

关键词：地方志办公室新疆伊犁州编纂工作对口支援设区市编纂始末江苏省工作组

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Influence of CaO on damping capacity and mechanical properties of Mg alloy

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中国有色金属学会会刊：英文版 2009年第B09期19卷 76-79页

作者： Dong-In JANG Jin-Kyu LEE Dae-up KIM Shae-K KIM Advanced Material Division Korea Institute of Industrial Technology Hyudai Mobis

For developing cost effective damping Mg alloys with high damping capacity and better mechanical properties, the microstructures, the mechanical properties at room temperature and the damping capacity of Mg alloy adding CaO were investigated and compared with those of K1A alloy. CaO adding into pure Mg maintains the damping capacity and increases the ultimate tensile strength compared with those of pure Mg. Mg-CaO alloy can be regarded as cost-effective damping alloy with high damping and mechanical properties as well as with the advantages of improving oxidation and burning resistances.

关键词：阻尼能力力学性能镁合金氧化钙成本效益微观结构阻尼性能电阻合金

Non-invasive prediction of forthcoming cirrhosis-related complications

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World Journal of Gastroenterology 2014年第10期20卷 2613-2623页

作者： Wonseok Kang Seung up Kim Sang Hoon Ahn Department of Internal Medicine Institute of Gastroenterology Yonsei University College of Medicine Seoul 120-752 South Korea Liver Cirrhosis Clinical Research Center Seoul 120-752 South Korea

In patients with chronic liver diseases,identification of significant liver fibrosis and cirrhosis is essential for determining treatment strategies,assessing therapeutic response,and stratifying long-term *** liver biopsy remains the reference standard for evaluating the extent of liver fibrosis in patients with chronic liver diseases,several non-invasive methods have been developed as alternatives to liver *** of these non-invasive methods have demonstrated clinical accuracy for diagnosing significant fibrosis or cirrhosis in many cross-sectional studies with the histological fibrosis stage as a reference ***,non-invasive methods cannot be fully validated through cross-sectional studies since liver biopsy is not a perfect surrogate endpoint ***,recent studies have focused on assessing the performance of non-invasive methods through longterm,longitudinal,follow-up studies with solid clinical endpoints related to advanced stages of liver fibrosis and *** a result,current view is that these alternative methods can independently predict future cirrhosis-related complications,such as hepatic decompensation,liver failure,hepatocellular carcinoma,or liver-related *** clinical role of non-invasive models seems to be shifting from a simple tool for predicting the extent of fibrosis to a surveillance tool for predicting future liver-related *** this article,we will summarize recent longitudinal studies of non-invasive methods for predicting forthcoming complications related to liver cirrhosis and discuss the clinical value of currently available non-invasive methods based on evidence from the literature.

关键词： Non-invasive model Prediction Cirrhosis Complication Liver-related events

Acute limb ischemia after minimally invasive cardiac surgery using the ProGlide:A case series

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World Journal of Clinical Cases 2022年第35期10卷 13052-13057页

作者： Jonggeun Lee up Huh Seunghwan Song Chung Won Lee Department of Thoracic and Cardiovascular Surgery Pusan National University School of MedicineBiomedical Research InstitutePusan National University HospitalBusan 49241South Korea

BACKGROUND We report two cases of acute femoral artery occlusion following the use of ProGlide in minimally invasive cardiac surgery and insertion of large-bore catheters through the common femoral *** will add to the existing body of literature by highlighting the possible complications associated with the use of ProGlide and reiterate that the use of the sono-guided ProGlide skill will reduce the incidence of these *** SUMMARY A 78-year-old man underwent minimally invasive cardiac surgery for severe aortic valve *** the operation,the puncture site of the common femoral artery was closed using *** next morning,after regaining consciousness,he complained of pain,motor weakness(grade 2),and coldness in the right lower extremity.A 65-year-old man underwent minimally invasive cardiac surgery for a large secundum atrial septal defect(5 cm×5 cm).After the operation,the puncture site of the common femoral artery was closed using *** extubation,the patient complained of paresthesia of the right *** the patients underwent emergency surgery for acute occlusion of the common femoral *** If the sono-guided ProGlide skill is used,complications can be prevented,and ProGlide can be safely used.

关键词： ProGlide Acute common femoral artery occlusion Minimal invasive cardiac surgery Sono-guided Femoral artery stenosis Case report