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Double Compression of Left Atrium and Pulmonary Artery by a Huge Descending Aortic Aneurysm with Intramural Hematoma Mimicking Pulmonary Embolism: A Case Report

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World Journal of Cardiovascular Diseases 2019年第6期9卷 419-424页

作者： Djibril Marie BA Aminata Diack Alain Affangla Khadidiatou Dia Mouhamed Cherif mboup Mouhamed Leye Abdoul Kane Unit of Training and Research in Medical Sciences University of Thies Thies Senegal Department of Radiology Principal Hospital of Dakar Dakar Senegal Department of Cardiology Principal Hospital of Dakar Dakar Senegal Department of Cardiology Cheikh Anta Diop University Dakar Senegal

Hemodynamic instability secondary to left atrial (LA) compression by an aortic aneurysm is a rare entity. We report?the case of a 43-year old woman with no previous diagnosis of congestive heart failure who was admitted for an initial diagnosis of pulmonary embolism (PE) based on shortness of breath, hypotension and D-Dimers?elevation. The electrocardiogram and blood counts were within normal limits. The chest X-ray revealed widening of the mediastinum. Transthoracic echocardiography demonstrated LA compression by a large descending thoracic aortic aneurysm. Left and right ventricle systolic functions were preserved. Chest angiography showed LA and left pulmonary artery (LPA) compression by a descending aortic aneurysm and an intramural hematoma with no evidence of PE evidence. Emergency surgery could not be done because of her financial status. She was treated medically and was discharged 1?week later with significant improvement. However she remained hypotensive.

关键词： Aortic Aneurysm Left Atrium Compression Pulmonary Artery Compression Intramural Hematoma Echocardiography

Conservative Approach Might Be the Strategy by Default in Stable Angina Patients: A Case Report

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World Journal of Cardiovascular Diseases 2020年第11期10卷 769-774页

作者： Serigne Cheikh Tidiane Ndao Mame Madjiguene Ka Djibril Marie Ba Khadidiatou Dia Mouhamed Chérif mboup Pape Diadie Fall Department of Cardiology Hospital Principal Dakar Dakar Senegal

Management of stable angina is still a matter of debate. Whether a conservative or invasive approach is better remains unclear. Even though recent large-scale randomized trials depict the conservative strategy as safe and efficient. In this report, we present a case of a 53-year-old male patient with cardiovascular risk factors of hypertension and hypercholesterolemia. He complained about typical chest pain at exertion. The coronary angiogram (CA) revealed severe stenosis of the proximal left anterior descending artery (LAD) ostium. After heart team discussion, coronary artery bypass graft (CABG) was advocated. However, due to a lack of means, the CABG was postponed. Meanwhile, he was managed with guideline-based medical therapy. In addition, he exercised regularly and adopted a healthy diet. Evolution was favorable with excellent symptoms control. A regular follow-up was organized with his cardiologist. A new CA before an eventual CABG six years later showed a significant plaque volume regression of the proximal LAD. We decided to continue conservative management. The stress echocardiogram to assess symptoms and exercise tolerance was normal. Our patient was sent to surgery on top of optimal medical therapy even though angioplasty was a good indication and was feasible. However, while he was struggling to afford the CABG procedure, he adopted a very healthy lifestyle along with medical therapy. Six years later, the result of that approach was without appeal, suggesting and reinforcing the conservative management

关键词： Stable Angina Chronic Coronary Syndrome Conservative Treatment Case Report

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地方统计数据对千年发展目标地方化至关重要

人类居住 2005年第4期 26-27页

作者： Gora mboup 宗思语联合国人居署监测与研究处

为实现中有关贫民窟的目标所做的贫民窟与其它城市贫困群体的街区和家庭一级的统计数据工作目前还做的不够.这是由于国家的统计报告对他们从所有城市家庭中收集出来的数据进行了平均化,不考虑家庭的贫富状况取出一个平均数,在贫困程度... 详细信息

为实现中有关贫民窟的目标所做的贫民窟与其它城市贫困群体的街区和家庭一级的统计数据工作目前还做的不够.这是由于国家的统计报告对他们从所有城市家庭中收集出来的数据进行了平均化,不考虑家庭的贫富状况取出一个平均数,在贫困程度、教育、健康、就业与人类住区状况等问题上提供单一的测算数据.

关键词：统计数据地方化贫困人口数据工作统计报告人类住区贫民窟平均数城市家庭

Frailty in People Living with Human Immunodeficiency Virus Aged 50 Years and Older: Prevalence and Predictors

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Chronic Immune Activation and Sexual Exposure among HIV Serodiscordant Couples in Senegal

World Journal of AIDS（艾滋病） 2024年第1期 18页

作者： Alassane Ndiaye Ndèye Fatou Ngom Kiné Ndiaye Assiétou Gaye Elhadji Bara Diop Ahmadou mboup Houlèye Saou Bessoume Sy Ababacar Niang Betty Fall Mame Awa Faye

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Advances in Infectious Diseases 2019年第2期9卷 122-136页

作者： Assane Diouf Helen Trottier Moustapha Mbow Abdoulaye Seck Khadim Dramé Cheikh Tidiane Ndour Moussa Seydi Souleymane mboup Vinh-Kim Nguyen Assan Jaye Department of Infectious Diseases/Regional Research and Training Center on HIV and Associated Diseases Fann’s University Hospital Center Dakar Senegal School of Public Health Department of Social and Preventive Medicine Université de Montréal Montreal Canada Sainte-Justine University Hospital Research Center Montreal Canada Department of Immunology FMPO Cheikh Anta Diop University Dakar Senegal Pasteur Institute Dakar Senegal Division of Fight against Aids (DLSI) Dakar Senegal IRESSEF: Institut de Recherche en Santé de Surveillance épidémiologique et de Formation Dakar Sénégal Research Center of the Montreal University Hospital Center (CRCHUM) Montreal Canada Medical Research Council Unit The Gambia London School of Hygiene & Tropical Medicine Fajara The Gambia

Purpose: In Sub-Saharan Africa, an important proportion of incident HIV cases occur among heterosexual serodiscordant couples (HSDC) but the majority of HIV negative partners can remain seronegative. These are called HIV-exposed seronegative (HESN). We aimed to compare immune activation (IA) levels between HESN, their HIV infected counterparts (HIV+ partners) and HIV unexposed uninfected individuals (HIV-neg Controls) and to evaluate the association between sexual exposure to HIV (SEHIV) and IA. Methods: We conducted a cross-sectional study in Dakar, Senegal on 148 participants recruited between November 2013 and February 2014: 40 HIV-neg Controls, 54 HESN and 54 HIV+ Partners. SEHIV was evaluated individually using questionnaires. IA level was measured by plasma level of β2-microglobulin (β2m). Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) for the different associations. Results: The median levels of β2m were 1.57 mg/l (IQR: 1.37 - 1.77), 2.14 mg/l (IQR: 1.76 - 2.43) and 2.24 mg/l (IQR: 1.80 - 3.17) for HIV-neg Controls, HESN and HIV+ partners, respectively. After adjustment, HESN had similar levels of IA with HIV+ partners but significantly higher than that of HIV-neg Controls (adjusted OR = 6.28;95% CI: [2.19 - 18.00]). The association between IA and SEHIV was evaluated in the HIV negative individuals. High frequency of SEHIV was associated with a β2m > 2.2 mg/l (OR = 6.56;95% CI: [1.71 - 25.21]);significantly more than median cut off value of >1.81 mg/l. Conclusions: Our study shows that, despite being uninfected with HIV, HESN individuals show a high level of IA, which was depended on the level of SEHIV.

关键词： HIV Serodiscordant Couples Immune Activation Sexual Exposure

Late Diagnosis of Takayasu Disease in a 50-Year-Old African Black Woman with Repeated Episodes of Heart Failure: Seeing the Forest through the Trees—A Case Report

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World Journal of Cardiovascular Diseases 2020年第10期10卷 683-697页

作者： Djibril Marie BA Aminata Diack Alain Affangla Serigne Cheikh Tidiane Ndao Madjiguene KA Khadidiatou DIA Mouhamed Cherif mboup Mouhamed Leye Unit of Research and Training in Medical Sciences University of Thies Thies Senegal Department of Radiology Principal Hospital of Dakar Dakar Senegal Department of Cardiology Principal Hospital of Dakar Dakar Senegal

Background: First described in 1908, TAK has now been recognized as a non-specific inflammatory disease of unknown etiology, predominantly affecting young females. Sometimes, it progresses into relatively rare and potentially fatal scenarios such heart failure. Case Presentation: Here, we present the case of a 50-year sub-saharan female suffering from acute heart failure related to TAK. Despite constitutional symptoms (fever, malaise, weight loss) and more characteristic features such claudication of lower extremities, carotydinia, and pulseless syndrome, diagnosis of TAK was delayed since main presentation was heart failure. Immunosuppressive and anticoagulant therapies have induced improvement in cardiac manifestations. Conclusion: Early diagnosis and proper treatment can protect the patient from dangerous complications such heart failure.

关键词： Takayasu Heart Failure Corticotherapy Pulseless Syndrome Sub-Saharan Black Female Case Report

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收集正确的数据——保障妇女权益

人类居住 2005年第3期 11-12页

作者： Gora mboup Mary Amuyunzu-Nyamongo 宗菁联合国人居署监测研究部门非洲健康和发展研究所

在发展过程中，现行的性别主流化战略在解决贫困妇女问题方面还有很大的差距。这主要是由于现行的工具和手段所依赖的国别数据常常弩虑了城乡差别，而忽视了性别差异。

关键词：妇女权益数据收集性别政府管理基础设施

Self-Medication of Senegalese Women through Social Networks

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Health 2020年第4期12卷 396-406页

作者： Niang Khadim Jean A. D. Tine mboup Fatima Zahra Bassoum Omar Fatoumata B. Diongue Amadou I. Diallo Faye Adama Public Health Department Gaston Berger University (UGB) of Saint-Louis Senegal Institut de Santé et Développement Cheikh Anta Diop University Dakar Senegal

Self-medication is a form of self-care which has evolved considerably with the development of digital technology. It particularly challenges public health actors given the risks to which it may be exposed if it is not properly supervised. The aim of this work was to study the knowledge, attitudes and practices of Senegalese women on self-medication through social networks. A transversal descriptive study was conducted from June 10 to 30, 2019. It concerned all Senegalese women registered in at least one of the following women’s Facebook groups: Femme chic, Femme leader, Ladies club or Entre yaays. A study information sheet was posted on the wall of these different groups, and enabled consenting women to find a questionnaire deployed online directly through a link. Consenting women were able to complete the data collection tool directly online. The proportions were compared by setting the alpha risk at 5%. A total of 508 women were surveyed. The results thus showed a high prevalence (68.9%) of self-medication. A proportion of 46.3% of those self-medicated used Facebook or the Internet as a source of information to find the drugs to use. The advice received from these groups related to hygiene and dietary measures (96.1%), consultation with health personnel (54.6%), consultation with a traditional healer (50.4%) and taking medication (41.8%). The health problems most treated with these self-medications were headaches ((84.6%) and painful periods (45.1%). Simple analgesics (84.6%) and vitamins (66.9%) were the most recommended drugs, but it was also found antibiotics (40.0%), centrally acting analgesics (20.0%), anti-diabetics (6.9%) and antihypertensive (5.4%). Oral tablets (92.3%) remained the most widely used dosage forms, but eye drops (5.4%) and injectables (5.4%) were also found. Although searching for information on Facebook/internet, women obtained the drugs from pharmacies (72.4%) or the family medicine box (19%). Regarding self-medication on Facebook, its eas

关键词： Automedication Women’s Health Internet Social Networks Senegal

Pulmonary Embolism in Young Patients: About 24 Cases at the Cardiology Department of Dakar Principal Hospital in Senegal

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World Journal of Cardiovascular Diseases 2019年第9期9卷 632-638页

作者： Joseph Salvador Mingou Amadou Tidjani Saadou Madjiguene Ka Zoumana Sangaré Serigne Cheikh Tidiane Ndao Khadidiatou Dia Mouhamed Cherif mboup Pape Diadié Fall Department of Cardiology Hospital Principal Dakar Senegal Departement of Cardiology Hospital Aristide Le Dantec Dakar Senegal

Introduction: Pulmonary embolism is a relatively common life-threatening cardiovascular emergency. It remains a diagnostic problem because of its nonspecific clinical signs. Objective: The general objective was to study pulmonary embolism in young patients admitted to the cardiology department of Dakar Principal Hospital in Senegal. Methodology: This was a retrospective, descriptive and analytical study in the cardiology department of the Dakar Principal Hospital over a period of two (02) years from January 1, 2015 to December 31, 2016 in young patients admitted for pulmonary embolism. Results: We collected 24 patients with a hospital prevalence of 2.18%. The average age was 42.29 years ± 8.41 years with a male predominance (sex ratio of 1.6). The Wells probability score was low in 54.16% of patients and medium in 45.83%. Functional signs were dominated by chest pain (83.33% of cases) followed by dyspnea (79.16% of cases). The thromboembolic risk factors found were gynecological-obstetrical in 16.6% of cases followed by prolonged bed rest. One case of thrombophilia was present with a deficiency of protein C and antithrombin III. The electrocardiogram recorded sinus tachycardia in 29.16% of patients;the Mac Ginn White sign (S1Q3T3) was found in 25% of cases. Echocardiography showed pulmonary arterial hypertension in 12.48% of cases, dilation of the right ventricle and a paradoxical septal motion in 14.28% of cases. CT pulmonary angiography showed 63.63% of cases with bilateral pulmonary embolism;it was unilateral in 22.72% of cases. Long-term anticoagulation was based on acenocoumarol 4 mg (66.7%) and Rivaroxaban (33.3%). 62.5% of the patients were seen at the 3rd month, when a checking was made to evaluate the tolerance of the treatment, and the evolution of the patient. Conclusion: Pulmonary embolism is not a rare condition in young subjects but is often underdiagnosed. Gyneco-obstetrical factors are predominant in this age group. Direct oral anticoagulants are mor

关键词： Pulmonary Embolism Young Patients Dakar (Senegal)