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Chinese Medicine 2018年第4期9卷 165-178页

作者： Yuxin Chen Qigui Mo Baibo Xie Bingxin Ma Xinyu Zang Gao Zhou Linyou Cheng james Hua Zhou Youwei Wang Institute of TCM and Natural Products School of Pharmaceutical Sciences Wuhan University Wuhan China Beijing Hebabiz Biotechnology Co. Ltd. Beijing China National and Region joint Engineering Center for Anticancer Drug Development Guangxi Hebabiz Pharmaceutical Co. Ltd. Qinzhou China MOE Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Wuhan University Wuhan China

Background: To explore the hepatoprotective effect of Yigan mingmu oral liquid (YGMM) on isoniazid-rifampicin induced liver injury in rats. Methods: Total 38 SD rats were randomly divided into 6 groups including control group, model group, silymarin positive control group, and three YGMM treatment groups. Model group was administered intragastrically with INH (100 mg/kg) and RIF (100 mg/kg) for 14 days. Silymarin group and YGMM treatment groups were administered intragastrically with silymarin (100 mg/kg) and different doses of YGMM (1, 2.5, 5 mg/kg) 2 hours before INH and RIF administration from day 4 to day 14.?Results: Rats were sacrificed 16 hours after the last day treatment to determine the activities of serum alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP), as well as total bilirubin (TB) content. Oxidative stress was evaluated by measuring total superoxide dismutase (T-SOD) and malondialdehyde (MDA) levels. Histopathological changes in liver tissues were observed under an optical microscope by using hematoxylin and eosin staining. The mice?in model groups showed significantly (p < 0.05) increased levels in AST, ALT, ALP, TB and MDA compared to their control groups;and showed significantly (p < 0.05) decreased level in T-SOD. These changes were significantly (p < 0.05) reversed by the YGMM treatments in a dose-dependent manner. Hepatic pathological changes were attenuated or even reversed by silymarin or YGMM treatments. Conclusions: YGMM has a good hepatoprotective activity on isoniazid-rifampicin induced liver injuries in rats.

关键词： Herbal Prescription Hepatoprotective Activity Isoniazid Rifampicin Oxida-tive Stress

Experimental Analysis of Interacting HT22 Plasma Membrane Cholesterol and β-Amyloid

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Advances in Alzheimer's Disease 2017年第4期6卷 75-96页

作者： George Livadiotis Leila Assas Maher A. Dayeh Saber Elaydi Chloe Phea james L. Roberts Yara Samman Rachel Tchen Southwest Research Institute San Antonio USA Department of Mathematics King Abdul Aziz University Jeddah Saudi Arabia Trinity University San Antonio USA

The peptide β-Amyloid (β-A) is known to be one of the primary factors causing neurodegeneration in the Alzheimer disease. Hence, one would like to know the factors that would increase or decrease the toxicity of β-Amyloid in the brain. One of the factors that are debated in the literature is cholesterol, where it is not clear if modulating the levels of cholesterol would affect the degree of toxicity of β-Amyloid on neuron cells in the brain. In order to investigate this problem, data were collected and analyzed for three types of experiments: 1) Correspondence between cholesterol and methyl-β-cyclodextrin (MβCD) measurements;2) measurements of the relative fluorescence unit (RFU) with respect to MβCD concentration (with/without β-A);and 3) RFU measurements with respect to β-A concentration (with/without MβCD). HT22 hippocampal neurons immortalized with the simian virus SV-40 large T-antigen plasmid vector were used to conduct the experiments. Mito-ID Membrane potential cytotoxicity was used as a measure of mitochondrial potential change. The statistical analysis of the presented experimental results indicates that cholesterol has no statistically significant effect on the degree of toxicity of β-Amyloid.

关键词： Alzheimer Disease β-Amyloid Cholesterol

心理学研究手册 a guide for graduate students and research assistants

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心理学研究手册 a guide for graduate students and research as...

Hybrid ameloblastoma in a nigerian: Report of a case and review of literature

2006年

作者：（美）Frederick T. L. Leong （美）james T. Austin 周晓林等译

万千心理:本书包括：寻找研究主题、有效利用图书馆、进行文献检索、阅读和评价研究文章、邮件调查、从团体中收集数据等共29章内容介绍了心理学的研究。

关键词：哲学、宗教心理学心理学研究方法

来源：汇雅图书（南通市图书馆... 评论

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Open Journal of Stomatology 2013年第7期3卷 347-353页

作者： O. A. Effiom O. james O. T. Akeju A. S. Salami O. Odukoya Department of Oral and Maxillofacial Surgery College of Medicine University of Lagos Lagos Nigeria Department of Oral Pathology and Oral Biology College of Medicine University of Lagos Lagos University Teaching Hospital Lagos Nigeria Department of Oral Pathology and Oral Biology Lagos University Teaching Hospital Lagos Nigeria

Background: Hybrid Ameloblastoma is a rare type of ameloblastoma that is presently receiving attention in some quarters. Altogether, less than 30 cases have been reported in the scientific literature, thus calling for the need to report more cases in order to add to the body of knowledge on this lesion. This case report is aimed to add to the number of cases that are building up in the scientific literature. Materials and Methods: A 50-year-old female presented with a 3-year history of an anterior mandibular swelling extending from the body of the mandible on the right to the body of the mandible on the left. Orthopantomograph of the lesion revealed a mixed radiolucent and radiopaque lesion that extended from the distal region of the right mandibular second premolar to distal region of the left mandibular second molar. Segmental mandibulectomy with immediate replacement with reconstruction was undertaken. Results: Specimen which was subjected to histopathologic examination reported a diagnosis of Keratinizing Follicular Ameloblastoma and Desmoplastic Ameloblastoma with Osteoplasia, consistent with a diagnosis of Hybrid Ameloblastoma. There has been no sign of recurrence 7 months after a regular follow-up and the patient is planned for a long term follow-up. Conclusion: Besides histological details that combine both conventional ameloblastoma and desmoplastic ameloblastoma, the present case of hybrid ameloblastoma bears similar clinical features as well as treatment modalities to that of conventional solid multicystic ameloblastoma.

关键词： Ameloblastoma Hybrid Nigerian

碳酸盐岩孔隙度和热成熟度之间的经验关系:区域性孔隙度预测方法

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宝石和宝石学杂志(中英文) 1986年第2期 84-92页

作者： james W Schmoker 万静萍

资料表明,地下碳酸盐岩中孔隙度的减少可以经验地用幂函数θ=a（TTI）b来表示,这里θ是区域性的孔隙度,TTI是Lopatin的热成熟度时间—温度指数,指数b大致等于-0.372,而乘数a对某一给定的数据总体是常数,但可以有一个数量级范围内的变化... 详细信息

资料表明,地下碳酸盐岩中孔隙度的减少可以经验地用幂函数θ=a（TTI）b来表示,这里θ是区域性的孔隙度,TTI是Lopatin的热成熟度时间—温度指数,指数b大致等于-0.372,而乘数a对某一给定的数据总体是常数,但可以有一个数量级范围内的变化。公式的含意如下: 1.由于埋藏成岩作用使碳酸盐岩孔隙度的减少是一种和温度呈指数关系、和时间呈线性关系的成熟过程。 2.指数基本上和岩石基质无关,可能反映扩散迁移的临界速度过程。 3.乘数a体现了所有沉积和成岩参数对孔隙的总效应。在区域性的测量规模下,碳酸盐岩孔隙度的预测值用热成熟函数来表示。也可以估算在烃生成、运移或圈闭时期碳酸盐岩的孔隙度。

关键词：孔隙度预测白云岩灰岩碳酸盐岩化学岩热成熟度区域性

手术后少尿,体液,电解质代谢失调和酸碱失衡(连载之一)

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右江医学 1985年第2期 47-52页

作者： james D.Hardy 周英杰

体液和电解质代谢失调是治疗各种危重外科病人中常遇到的问题。及时发现、有效处理以至预防性处置,是治疗这些病人的重

关键词：少尿代谢失调尿性肾衰乏尿症肾功能衰竭血容量减少手术后危重病人外科病人尿量传导材料电解质

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磨蚀性浆液用机械密封

化肥设计 1987年第5期 75-80页

作者： james S.Budrow 黄汉华 Durametallic公司

合悬浮状磨蚀颗粒的液体以及可能形成磨蚀结晶的浓缩液,对必须为泵类设备选择机械密封的工程师提出了棘手的问题。本文讨论的若干种密封对我们所遇到的几种不同"类型"的磨蚀性流体都十分合适。

关键词：单端面密封流体碳化硅碳化钨钨化合物动密封机械密封静密封波纹管密封磨蚀性

<i>Imperata yellow mottle virus</i>: An Emerging Threat to Maize, Sorghum and Pearl Millet in Burkina Faso

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Agricultural Sciences 2017年第5期8卷 397-408页

作者： Moustapha Koala Valentin Stanislas Edgar Traoré Drissa Sérémé Bouma james Neya Christophe Brugidou Nicolas Barro Oumar Traoré Laboratoire Mixte Internationale (LMI) Patho-Bios Institut de l’Environnement et de Recherches Agricoles (INERA) Ouagadougou Burkina Faso Universite Ouaga I Professeur Joseph Ki-Zerbo Ouagadougou Burkina Faso UMR IPME (UM IRD CIRAD) Institut de Recherche pour le Développement IRD Montpellier France

Imperata yellow mottle caused by Imperata yellow mottle virus (IYMV) of the genus Sobemovirus was first characterized on Imperata cylindrical and Zea mays in Burkina Faso. The disease has been reported in several localities of the country but its ecology and epidemiology are poorly known. In particular, only I. cylindrical and maize have been reported within IYMV host range. The aim of this study was to investigate the experimental host range of the virus. Mechanical inoculation of a mixture of four IYMV isolates to 18 plant species, including four crops (maize, rice, sorghum and pearl millet) and 14 wild grasses showed clear mottle symptoms in maize, sorghum and pearl millet and two wild grass species (Setaria verticillata and Rottboellia exaltata). Symptom development was confirmed by Enzyme-linked immunosorbent assay and reverse transcription–polymerase chain reaction (RT-PCR). Infection of crop species by IYMV depended on cultivars tested. Therefore, proportions of positive cultivars were 16/36 in maize, 4/10 in sorghum and 4/9 in pearl millet, respectively. Studies on virus-host interactions using individual virus isolates showed two pathogenic patterns. Three out of the four isolates tested infected all plant species and cultivars. In contrast, the fourth IYMV isolate could infect only one maize cultivar. These results expand the previously known host range of IYMV from two to five species, indicating a narrow host range. Among the new characterized host species, sorghum and pearl millet are important cereal crops. Therefore, Imperata yellow motte disease is a potential threat for the cereal crop production and its ecology and epidemiology should be thoroughly investigated.

关键词： IYMV Sobemovirus Host Range Virus-Host Interactions

Medical Image Registration Using the Fourier Transform

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2014年第1期3卷 49-55页

作者： Jason Luce james Gray Mark A. Hoggarth Jeffery Lin Elizabeth Loo Maria I. Campana John C. Roeske Department of Radiation Oncology Loyola University Medical Center Maywood USA Department of Radiation Oncology Loyola Universty Medical Center Maywood USA

A Fourier Transform (FT) based pattern-matching algorithm was adapted for use in medical image registration. This algorithm obtained the FT of two images, determined the normalized cross-power spectrum of the transformed images, and then applied an inverse FT. The result was a delta function with a maximum value at the location corresponding to the distance between the two images;a similar method was used to recover rotations. This algorithm was first tested using a simple two-dimensional image, with induced shifts of ±20 pixels and ±10 degrees. All translations were recovered with no error and all rotations were recovered within 0.18 degrees. Subsequently, this algorithm was tested on eight clinical kV images drawn from four different body sites. Twenty-five random shifts and rotations were applied to each image. The average mean error of the registration solution was -0.002 ± 0.077 mm in the x direction, 0.002 ± 0.075 mm in the y direction, and -0.012 ± 0.099 degrees. These initial results suggest that a FT algorithm has a high degree of accuracy when registering clinical kV images.

关键词： Image Registration Fourier Transform Pattern Matching