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关于人氟齿中葡萄糖葡聚糖的硫酸异状体的研究

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国外医学（医学地理分册） 1989年第2期10卷 83-83,F003页

作者： Sush.,ak 都玲玲

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环孢菌素在皮肤病领域中的应用

国外医药（抗生素分册） 1990年第5期11卷 377-381页

作者： Cupta ak 徐积恩

环孢菌素(Cyclocporine)是一种天然的亲脂性环状肽,由11个氨基酸组成。1972年瑞士山道士公司实验室首先由Tolypocladium inflatum gams分离的抗真菌产物,以后发现本品有很强的免疫抑制性质,1978年首先用于人体器官移植,后来用于防止器... 详细信息

环孢菌素(Cyclocporine)是一种天然的亲脂性环状肽,由11个氨基酸组成。1972年瑞士山道士公司实验室首先由Tolypocladium inflatum gams分离的抗真菌产物,以后发现本品有很强的免疫抑制性质,1978年首先用于人体器官移植,后来用于防止器官排斥反应,用于其它方面的报道也越来越多。一、药理学环孢菌素可以口服和静注给药,而肌注给药由于吸收不规则未被推荐。口服后胃肠道内食物可影响本品的吸收,在2-4小时内可达到血峰浓度,生物利用度约为30%。本品在肝内代谢,通过肝内单氧化酶系统。

关键词：环孢霉素皮肤病临床应用

Percutaneous management in hepatic alveolar echinococcosis:A sum of single center experiences and a brief overview of the literature

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World Journal of Gastrointestinal Surgery 2023年第3期15卷 398-407页

作者： Suat Eren Sonay Aydın Mecit Kantarci Volkan Kızılgöz akın Levent Düzgün CanŞenbil Okan akhan Department of Radiology Faculty of MedicineAtatürk UniversityErzurum 25100Turkey Department of Radiology Faculty of MedicineErzincan Binali Yıldırım UniversityErzincan 24100Turkey Department of Radiology Hacettepe UniversityAnkara 06090Turkey

BACKGROUND Hepatic alveolar echinococcosis(HAE)is a serious zoonotic infection that affects *** may have a tumor-like appearance at *** treatment of HAE patients is extremely relaxing for *** is a significant human zoonotic infection caused by the fox tapeworm Echinococcus Multilocularis *** possesses the characteristics of an invasive tumor-like lesion due to its infiltrative growth pattern and protracted incubation *** disease is endemic over central Europe,Asia,and North *** To characterize HAE patients who were treated percutaneously,their outcomes,and the major technical features of percutaneous treatment in *** Patients who were treated with percutaneous cyst drainage and/or percutaneous biliary drainage were included in the *** abnormal coagulation values and solid or non-infected HAE with minor necrotic change were *** Thirty-two patients underwent percutaneous cyst drainage,two patients underwent percutaneous biliary drainage,and four patients underwent percutaneous biliary drainage *** radiology is utilized to drain echinococcal necrosis and abscesses within/without the liver,as well as diseased and clogged bile *** Percutaneous drainage of cyst contents and/or biliary channels using a minimally invasive technique is a very *** cyst drainage with albendazole therapy improves quality of life in patients who are unable to undergo surgery,even when the mass resolves with long-term treatment.

关键词： Interventional Radiology Treatment Alveolar echinococcosis Liver

Intelligent automated system based on a fuzzy logic system for plant protection product control in orchards

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International Journal of Agricultural and Biological Engineering 2019年第3期12卷 92-102页

作者： Peter Berk A.Belšak D.Stajnko M.Lakota N.Muškinja M.Hočevar J.Rakun Faculty of Agriculture and Life Sciences University of MariborPivola 102311 HoceSlovenia Faculty of Mechanical Engineering University of MariborSmetanova 172000 MariborSlovenia Faculty of Electrical Engineering and Computer Science University of MariborSmetanova 172000 MariborSlovenia Faculty of Mechanical Engineering University of LjubljanaAskerceva 61000 LjubljanaSlovenia

The spraying of plant protection product(PPP)in orchards is a very hazardous working procedure,owing to the spray drift caused by the uneven operation of conventional axial boom *** research describes an intelligent automated system for precise(PPP)distribution in *** is based on an intelligent decision-making model using ultrasonic measurements of leaf area density under laboratory conditions,which serve to trigger electromagnetic valves(EMV)on the axial boom sprayer.A fuzzy logic algorithm was an integrated part of the intelligent system for controlling the PPP by generating the pulse width modulation signal and applying it through the EMV of the prototype boom *** results showed that by using an intelligent decision-making model,the same efficiency as with conventional methods could be achieved,but with reduced usage of plant protection ***,the intelligent automated system used 4.8 times less spray mixture than the conventional one.

关键词： plant protection product boom sprayer electromagnetic valve fuzzy logic algorithm tree canopy

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T依赖性B细胞活化机理的重新评价

国外医学（免疫学分册） 1989年第1期12卷 32-35页

作者： Abbas ak 朱炳法

辅助T 细胞(T_H)在大多数蛋白抗原的抗体应答中起着关键作用,传统观点包括抗原结合于SmIg 和T_H 活化、增殖、分化两个阶段;在淋巴细胞活化中还盛行“双信号”学说,第一信号为“抗原桥”,第二信号为释放抗原特异因子和淋巴因子(如IL_2、... 详细信息

辅助T 细胞(T_H)在大多数蛋白抗原的抗体应答中起着关键作用,传统观点包括抗原结合于SmIg 和T_H 活化、增殖、分化两个阶段;在淋巴细胞活化中还盛行“双信号”学说,第一信号为“抗原桥”,第二信号为释放抗原特异因子和淋巴因子(如IL_2、IFNγ);最近将BCGF、BCDF 也归入此列。近年来,一些新的实验资料,包括B 细胞的“抗原提呈能力”、淋巴因子的效应、

关键词： B细胞活化辅助T细胞 T细胞

Increased syndecan-1 and glypican-3 predict poor perinatal outcome and treatment resistance in intrahepatic cholestasis

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Hepatobiliary & Pancreatic Diseases International 2020年第3期19卷 271-276页

作者： Basak Gümüs Güler Sibel Ozler Department of Health Sciences Istinye UniversityIstanbul 34010Turkey Department of Perinatology Selcuk University Faculty of MedicineKonya 42130Turkey

Background:Intrahepatic cholestasis of pregnancy(ICP)increases the risk of adverse pregnancy *** study aimed to explore the association between serum syndecan-1 and glypican-3 levels and the adverse perinatal outcome as well as the responses to the treatment of ursodeoxycholic acid(UDCA).Methods:This prospective,case control study included 88 pregnant women(44 women with ICP and 44 healthy controls).The primary end points were the perinatal outcome and the response to UDCA therapy.A logistic regression model was used to identify the independent risk factors of adverse pregnancy outcomes and reduced response to UDCA ***:Women with ICP had significantly higher serum syndecan-1(1.27±0.36 ng/m L vs.0.98±0.50 ng/m L;P=0.003),glypican-3(1.78±0.13 ng/m L vs.1.69±0.16 ng/m L;P=0.004),AST(128.59±1.44 vs.13.29±1.32 U/L;P<0.001),and ALT(129.84±1.53 vs.8.00±3.67 U/L;P<0.001)levels compared with the *** increased levels of syndecan-1(OR=4.715,95%CI:1.554–14.310;P=0.006),glypican-3(OR=8.465,95%CI:3.372–21.248;P=0.007),ALT(OR=1.382,95%CI:1.131–1.690;P=0.002),and postprandial bile acid(PBA)(OR=3.392,95%CI:1.003–12.869;P=0.026)were correlated to *** adverse neonatal outcome was related to increased glypican-3(OR=4.275,95%CI:2.726–5.635;P=0.039),and PBA(OR=3.026,95%CI:1.069–13.569;P=0.037).Increases of syndecan-1(OR=7.464,95%CI:2.130–26.153,P=0.017)and glypican-3(OR=6.194,95%CI:2.951–13.002;P=0.025)were the risk factors of decreased response to UDCA ***:Syndecan-1 and glypican-3 might be powerful determinants in predicting adverse perinatal outcome in patients with ICP,and they can be used to predict the response to the UDCA treatment.

关键词： Intrahepatic cholestasis of pregnancy Syndecan-1 Glypican-3 Adverse perinatal outcome Response to UDCA

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最后的苍凉与神秘第三次驱车进藏纪实

世界汽车 2007年第1期 124-129页

作者：津ak8360 都市牧人

第一次进藏,激动,面对神奇圣洁的土地,见到什么就拍什么,恨不能将所见所闻一并带走。但仅用取景器看、用胶片感光,对西藏的认识始终是肤浅的。第二次进藏,感动,总是迟迟不肯按动快门,有时甚至不想拿出相机,只想潜移默化地感受、不知不... 详细信息

第一次进藏,激动,面对神奇圣洁的土地,见到什么就拍什么,恨不能将所见所闻一并带走。但仅用取景器看、用胶片感光,对西藏的认识始终是肤浅的。第二次进藏,感动,总是迟迟不肯按动快门,有时甚至不想拿出相机,只想潜移默化地感受、不知不觉地吸纳。用眼睛去看,用灵魂去体会,开始明白今生或许再去10次,西藏也依然陌生。第三次开车进藏,火车通了,柏油路修好了,而心里却产生了一丝遗憾和失落。担心西藏能否依旧,害怕这片净土会被蜂拥而来的文明逐渐淹没。这次“西游”依然选择穿越艰难的藏北大地,试图再次体味她的苍凉与神秘……

关键词：取景器西藏柏油路火车

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新西兰全国范围高精度GPS网

测绘译丛 1992年第5期 15-18,26页

作者： Chong,ak 张献州

Bioactivity guided isolation of mosquito larvicide from Piper longum

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Asian Pacific Journal of Tropical Medicine 2011年第2期4卷 112-116页

作者： Madhu.S Kumar Vijayan VA Shaukath ak Vector Biology Research Lab Department of Studies in ZoologyUniversity of MysoreManasagangotriMysore 570 006KarnatakaIndia Department of Studies in Zoology University of MysoreManasagangotriMysore 570 006KarnatakaIndia Department of Chemistry Yuvaraja's CollegeUniversity of MysoreMysore-05India

Objective:To isolate the larvicidal component from the fruits of Piper longum（***） against the filariasis vector,Culex quinquefasciatus（***）.Methods:Pulverized fruits of *** were subjected to soxhlet extraction using series of organic solvents of increasing *** the solvent extracts were verified for their larvicidal efficacy against 4th instar larvae of *** employing standard WHO *** fractionation through column chromatography lead to the isolation of a bioactive amide, pipyahyine from the petroleum ether ***:Petroleum ether extract was found to be the most active fraction among all the extracts tested with LC50 and LC90 being 1.03 and 2.04 ppm ***,pipyahyine,an isolated component of the same fraction was found to be even more effective than the parent extract in terms of LC50 being 0.58 and 1.88 ppm respectively. Conclusions:From the results,it is evident that *** can be considered as a powerful arsenal for the control of mosquito population.

关键词： Piper longum Bioassay Pipyahyine Culex quinquefasciatus Filariasis Larvicide