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Determinants and Risks Factors of Renal Failure in Patients with Heart Failure in Cardiology Department of CHU Sylvanus Olympio of Lomé(Togo)

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Open Journal of Nephrology 2019年第3期9卷 65-76页

作者： Kossi Akomola Sabi Eyram Yoan Makafui Amekoudi Soudougoua Baragou Komlan Georges Tona Yaovi Afassinou machioude pio Béfa Noto-Kadou-Kaza Badomta Dolaama Eugene Ametepe Attisso Anani Amen Tevi Mawusse Koffi Mensah Mindessou Murielle Schyldia Bonou-Selegbe Jaques Vigan Department of Nephrology and Hemodialysis CHU Sylvanus Olympio Lomé Togo Department of cardiology CHU Sylvanus Olympio Lomé Togo Clinique de Néphrologie CNHU Cotonou Bénin

Introduction: The morbidity and mortality of patients with heart failure are known to increase rapidly in the presence of renal insufficiency, which is usually the cause but may be a consequence. To organize better prevention of renal failure, we undertook this study to identify the determinants of renal failure in the population of patients with heart failure. Methodology: This was a retrospective descriptive and analytical study of heart failure (HF) cases hospitalized from January 1st to December 31st, 2016, over a period for twelve (12) months at CHU Sylvanus Olympio. Patients who performed cardiac Doppler ultrasound were included in our study. Renal failure was defined as eGFR (estimated glomerular filtration rate) less than 60 ml/min/1.73m2. Multivariate logistic regression was performed to investigate associated factors. The dependent variable was DFG status: coded 1 if the GFR is less than 60 ml/min and 0 if not. Results: A total of 216 patients were included. The majority were female (54.17%). The median age of patients was 53 years [IQI = 32 - 61 years] with extremes of 15 and 96 years. 16.49% of patients had a GFR of less than 60 ml/min. In multivariate analysis the average standard of living (OR = 2.40, p = 0.0456), diabetes (OR = 2.67, p = 0.0300), hypertension (OR = 5.66, p = 0.0399), alcoholism (OR = 4.00, p = 0.0063) were the main factors in the development of an RF/HF. Conclusion: The average standard of living, diabetes, hypertension, and chronic alcoholism are the determinants of renal failure in HF.

关键词： Heart Failure Renal Failure Determinants Togo

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