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Design of Floating mass Type Piezoelectric Actuator for Implantable Middle Ear Hearing Devices

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Chinese Journal of Mechanical Engineering 2009年第2期22卷 221-226页

作者： LIU Houguang ta Na MING Xiaofeng RAO Zhushi State Key Laboratory of Mechanical System and Vibrations Shanghai Jiao Tong University Shanghai 200240 China

To overcome some of the problems inherent in conventional heating aids such as low gain at high fi＇equencies due to acoustic feedback, discomfort in occlusion of the extemal ear canal and so on, implantable middle ear hearing devices （IMEHDs） have been developed over the past two decades. For such kinds of IMEHDs, this paper presents the design of a floating mass piezoelectric actuator using a PMN-30%PT stack as a new type of vibrator. The proposed piezoelectric actuator consists of only three components of a piezoelectric stack, a metal case and a clamp. For the purpose of aiding the design of this actuator, a coupling biomechanics model of human middle ear and the piezoelectric actuator was constructed. This model was built based on a complete set of computerized tomography section images of a healthy volunteer＇s left ear by reverse engineering technology. The validity of this model was confirmed by comparing the motion of the tympanic membrane and stapes footplate obtained by this model with published experimental measurements on human temporal bones. It is shown that the designed actuator can be implanted on the incus long process by a simple surgical operation, and the stapes footplate displacement by its excitation at 10.5 V root-mean-square（RMS） voltage was equivalent to that from acoustic stimulation at 100 dB sound pressure level（SPL）, which is adequate stimulation to the ossicular chain. The corresponding power consumption is 0.04 mW per volt of excitation at 1 kHz, which is low enough for the transducer to be used in an implantable middle ear device.

关键词： piezoelectric actuator implantable middle ear hearing device floating mass fmite element model

Microstructure Stability of V and ta Microalloyed 12%Cr Reduced Activation Ferrite/martensite Steel during Long-term Aging at 650℃

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Journal of materials Science & Technology 2015年第3期31卷 311-319页

作者： Xiang Xiao Guoquan Liu Benfu Hu Jinsan Wang Wenbin ma School of materials Science and Engineering University of Science and Technology Beijing Chinalco Research Institute of Science and Technology Collaborative Innovation Center of Steel Technology University of Science and Technology Beijing

In view of developing novel alloys for applications in supercritical water-cooled reactor fuel cladding and in-core components, a 12%Cr reduced activation ferrite/martensite(RAFM) steel with good corrosion resistance and irradiation performance was developed. V and ta were added to form fine MX type carbonitrides and enhance the high temperature creep rupture strength. Microstructure stability of the steel during long-term aging at 650 C was studied experimentally combined with the simulation of ThermoCalc and DICTRA software. The results show that the precipitates in the steel during long-term aging contain M23C6, MX and Laves phase. M23C6 carbides play a major role in the stabilization of the tempered martensite lath structure by exerting a large Zener pinning force as compared with MX and Laves *** V and ta in the steel can not only promote MX precipitation, but also refine M23C6 carbides and thus improve the thermal stability of lath/subgrains, which is beneficial to the improvement of high temperature microstructure stability of the 12%Cr RAFM steel.

关键词： 12%Cr reduced activation ferrite/martensite steel

The long and the short of it： new insights on sperm length help demystify the complexities of sexual selection

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Asian Journal of Andrology 2016年第6期18卷 902-903页

作者： Alexander K Hill Dan ta Eisenberg Department of Anthropology University of Washington Seattle WA 98195 USA

Human sperm are approximately 6000th of a centimeter long, a smallfraction of a man＇s total body length. By contrast, fruit fly （Drosophila spp.） sperm can reach nearly 6 cm, roughly twenty times the total length of their bodies. This dramatic variation in male reproductive biology is explored in a recent paper from the journal Nature.

关键词： @@

Synthesis of the Silver Nanofluid by ASNSS Process

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过程工程学报 2004年第Z1期4卷 449-454页

作者： ta-Yu Chuang Depeartment of materials Engineering Tatung University Taipei 104 China Deaprtment of Chemical Engineering Yunlin University of Technology Yunlin County China

Arc Spray Nanoparticle Synthesis System (ASNSS) has been used to prepare the silver nanofluids in this study. The metal electrodes under the electrical discharge will melt and evaporate rapidly and condense to form the nanoparticles in the dielectric fluid at lower temperature and produce the suspended nanoparticle fluid. Thus, the mechanism of the ASNSS process is superheating the electrodes by plasma to form metallic nuclei and supercooling these nuclei by dielectric liquid to produce nanofluid. This study considers the different controlling parameters such as discharge current,discharge voltage, pulse-duration time, electrode diameter, and the temperature of dielectric liquid. The optimally operated parameters can be obtained to produce the finer particle size in nanofluid. The results indicate the silver electrodes in alcohol fluid will produce the spherical nanosilver particles. The mean particle size of silver in different dielectric liquid temperatures of-40, -20, 0, and 10℃ is about13.4, 15.8, 17.5, and 21.6 nm, respectively. This indicates that the well suspended fluid can be obtained by controlling the lower dielectric fluid temperature.

关键词： ASNSS nanoparticles dielectric liquid temperatures nanofluid Ag

magmatic Evolution and Mineralization Process of the Super-Large Shihuiyao Rb–Nb–ta Deposit,Southern Great Xing'an Range,China

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Acta Geologica Sinica(English Edition) 2016年第6期90卷 2275-2276页

作者： ZHOU Zhenhua CHE Hewei ma Xinghua GAO Xu MLR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesChinese Academy of Geological Sciences School of Earth Science and Mineral Resources China University of Geosciences

Rare metal ore reserves are an important strategic resource, and their metallogenic mechanism and mineralization studies have also been received widespread international attention.

关键词： In Nb magmatic Evolution and Mineralization Process of the Super-Large Shihuiyao Rb ta Deposit,Southern Great Xing’an Range,China

Functional,chemical,and sensorial properties of gluten-free fermented instant soup powders developed by use of mung bean and drum drying process

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Food Bioscience 2022年第3期47卷 1070-1081页

作者： Bilge taşkın NazlıSavlak Department of Food Engineering Faculty of EngineeringManisa Celal Bayar University45140YunusemreManisaTurkey

There is a potent demand to develop novel gluten-free food alternatives that are nutritious and ***-free instant fermented soup powder was developed by partial substitution of rice flour with mung bean *** of drum drying conditions;feed moisture(45–65%),drum rotating speed(0.6–2.2 rpm),and steam pressure(75–95 psi)on functional,chemical,sensorial,and morphological properties of soup powders were *** powders exhibited high protein content(20.52–22.62%)and remarkable amounts of dietary fibers(2.63–3.94%),total phenolics(2.23–3.64μg GAE/g),and antioxidant capacities(DPPH:6.28–9.96μmol TEAC/g,FRAP:26.02–42.88μmol/g).The instant structure of the soup powder was provided by water solubility(17.93–23.14%),water absorption(3.20–4.20 g/g),and gelatinization degree(82.92–97.60%)analyses,as well as SEM appearances and DSC *** conditions were determined as 57.55%feed moisture,1.00 rpm rotating speed,and 91.27 psi steam *** instant soup powders had enhanced chemical,functional and bioactive properties,and can be used practically in daily and social life by celiac patients or gluten sensitive *** bean was proven to be a valid option for novel application opportunities in gluten-free systems.

关键词： Gluten-free Antioxidant activity Mung bean Optimization Instant soup Drum drying Quality characteristics

Emerging role of galectin 3 in neuroinflammation and neurodegeneration

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Neural Regeneration Research 2024年第9期19卷 2004-2009页

作者： Brian M.Lozinski Khanh ta Yifei Dong Department of Clinical Neuroscience University of CalgaryCalgaryABCanada Deparment of Biochemistry Microbiology&ImmunologyUniversity of SaskatchewanSaskatoonSKCanada

Neuroinflammation and neurodegeneration are key processes that mediate the development and progression of neurological ***,the mechanisms modulating these processes in different diseases remain incompletely *** in single cell based multi-omic analyses have helped to identify distinct molecular signatures such as Lgals3 that is associated with neuroinflammation and neurodegeneration in the central nervous system(CNS).Lgals3 encodes galectin-3(Gal3),aβ-galactoside and glycan binding glycoprotein that is frequently upregulated by reactive microglia/macrophages in the CNS during various neurological *** Gal3 has previously been associated with non-CNS inflammatory and fibrotic diseases,recent studies highlight Gal3 as a prominent regulator of inflammation and neuroaxonal damage in the CNS during diseases such as multiple sclerosis,Alzheimer’s disease,and Parkinson’s *** this review,we summarize the pleiotropic functions of Gal3 and discuss evidence that demonstrates its detrimental role in neuroinflammation and neurodegeneration during different neurological *** also consider the challenges of translating preclinical observations into targeting Gal3 in the human CNS.

关键词： Alzheimer’s disease Galectin 3 microglia multiple sclerosis neurodegeneration neuroinflammation Parkinson’s disease therapeutics

Glutamic acid decarboxylase 65-positive autoimmune encephalitis presenting with gelastic seizure, responsive to steroid: A case report

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World Journal of Clinical Cases 2021年第19期9卷 5325-5331页

作者： Camerdy Yue Yang Sheng-ta Tsai Department of Neurology China Medical University HospitalTaichung 404332Taiwan

BACKGROUND Anti-glutamic acid decarboxylase(GAD)antibody is known to cause several autoimmune-related *** most known relationship is that it may cause type I *** addition,it was also reported to result in several neurologic syndromes including stiff person syndrome,cerebellar ataxia,and autoimmune *** ago,isolated epilepsy associated with anti-GAD antibody was first ***,the association between temporal lobe epilepsy and anti-GAD antibody has been ***,with improvements in examination technique,many more autoimmune-related disorders can be diagnosed and treated easier than in the *** SUMmaRY A 44-year-old female Asian with a history of end-stage renal disease(without diabetes mellitus)under hemodialysis presented with diffuse abdominal *** initial diagnosis was peritonitis complicated with sepsis and paralytic *** peritonitis was treated and she recovered well,but seizure attack was noticed during *** clinical impression was gelastic seizure with the presentation of frequent smiling,head turned to the right side,and eyes staring without focus;the duration was about 5–10 *** lobe epilepsy was recorded through electroencephalogram,and she was later diagnosed with anti-GAD65 antibody positive autoimmune *** seizure was treated initially with several anticonvulsants but with poor ***,she showed excellent response to intravenous methylprednisolone pulse *** consciousness returned to normal,and no more seizures were recorded after 5 d of intravenous methylprednisolone *** In any case presenting with new-onset epilepsy,in addition to performing routine brain imaging to exclude structural lesion and cerebrospinal fluid studies to exclude common etiologies of infection and inflammation,checking the autoimmune profile has to be *** the practice of modern medicine,autoimmune-related disorders are relatively treatab

关键词： Anti-GAD antibody GAD65 antibody Autoimmune encephalitis Gelastic seizure Electroencephalogram Case report

Study on the dynamic behavior of herringbone gear structure of marine propulsion system powered by double-cylinder turbines

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Science China(Technological Sciences) 2022年第3期65卷 611-630页

作者： XU JiangHai JIAO ChunXiao ZOU DongLin ta Na RAO ZhuShi State Key Laboratory of Mechanical System and Vibration Institute of VibrationShock and NoiseShanghai Jiao Tong UniversityShanghai 200240China Collaborative Innovation Center for Advanced Ship and Deep-Sea Exploration Shanghai 200240China

Propulsion systems powered by double-cylinder turbines(DCT)are widely used in large-scale ***,the nonlinear instability leads to hidden dangers associated with the safe operation,and there is a lack of theoretical and systematic research on this *** on the gear transmission principle and non-Newtonian thermal elastohydrodynamic lubrication(EHL)theory,a torsional model of a two-stage herringbone system forced by unsymmetrical load is *** nonlinear and time-varying factors of meshing friction,meshing stiffness,and gear pair backlash are included in the model,and multiple meshing states,including single-and double-sided impact are *** nonlinear phenomena of the dynamic system are explored and the effects of the unsymmetrical load on the system stability are *** results indicate that the stability of the gear system is improved,and that the back-sided impact gradually disappears with the increases of load ratio between the two inputs and the input load ***,it is found that the gear pairs on the low-load side experience more severe vibration than those on the high-load ***,the stability of the gear pairs decreases along the power transmission path of the multistage gear *** results of this research will be useful when making predictions of the stability of such systems and in the optimization of the load parameters.

关键词： DCT propulsion system DI-SO herringbone gears unsymmetrical load nonlinear instability mechanism