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Hypotrichidium tisiae(Gelei,1929)Gelei,1954:a unique hypotrichid ciliate having a highly specialized developmental pattern during binary division

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marine Life Science & Technology 2022年第4期4卷 536-550页

作者： Xiaotian Luo Jie Huang Honggang ma Yujie Liu Xiaoteng Lu William A.Bourland Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences Institute of HydrobiologyChinese Academy of SciencesWuhan430072China Institute of Evolution and marine Biodiversity&Key Laboratory of mariculture Ministry of EducationOcean University of ChinaQingdao266003China Department of Biology Shenzhen MSU-BIT UniversityShenzhen518172China Department of Zoology Faculty of ScienceCharles UniversityPrague12843Czech Republic

In sharp contrast to their pelagic relatives,the oligotrichs,the overwhelming majority of hypotrich ciliates inhabit the *** a few species,including those of the genus Hypotrichidium Ilowaisky,1921,have adapted to a planktonic *** ontogenetic mode of the highly differentiated ciliate,Hypotrichidium tisiae(Gelei,1929)Gelei,1954,is *** this study,the interphase morphology and the ontogenetic process of this species are ***,the previously unidentified ciliary pattern of Hypotrichidium is *** main morphogenetic features are as follows:(1)The parental adoral zone of membranelles is inherited completely by the proter and the oral primordium of the opisthe arises in a deep pouch.(2)Five frontoventral cirral anlagen(fva.are formed:fva.I contributes to the single frontal cirrus,fva.II–IV generate three frontoventral cirral rows,fva.V migrates and forms postoral ventral cirri.(3)All marginal cirral row anlagen develop de novo:each of the two left anlagen forms a single cirral row,while the single right anlage fragments into anterior and posterior parts.(4)Two dorsal kinety anlagen occur de novo,with the right one fragmenting to form kineties 2 and 3.(5)Two long caudal cirral rows are formed at the ends of dorsal kineties 1 and *** the basis of the morphogenetic features and phylogenetic analyses,the assignment of Hypotrichidium to the family Spirofilidae Gelei,1929 within Postoralida is *** establishment of separate families for the slender“tubicolous”spirofilids and the highly helical spirofilids is also validated.

关键词： Hypotrichs Ontogenesis Phylogeny Spirofilidae Systematics 18S rrNA gene

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rare manifestation of familial vitreous amyloidosis caused by Gly103Arg transthyretin

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International Journal of Ophthalmology(English edition) 2023年第7期16卷 1093-1099页

作者： Yan-Bing Feng Yan-Bo Shi Yan-Yan He Zhen-Yi ma Yi-Xing Zhu Wen-Qing Weng Department of Ophthalmology Jiaxing Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical UniversityJiaxing 314001Zhejiang ProvinceChina Jiaxing Key Laboratory of Diabetic Angiopathy Jiaxing 314001Zhejiang ProvinceChina Central Laboratory of Molecular Medicine research Center Jiaxing Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical UniversityJiaxing 314001Zhejiang ProvinceChina Department of Pathology Jiaxing Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical UniversityJiaxing 314001Zhejiang ProvinceChina The Third Affiliated Hospital of Zhejiang Chinese Medical University Hangzhou 310005Zhejiang ProvinceChina

AIM:To identify and analyze the genotype of the patients with special ocular manifestations of familial vitreous amyloidosis(fva.in a Chinese Han ***:Pars plana vitrectomy(PPV)surgery was performed on a 52-year-old Chinese woman presented with vitreous amyloidosis and progressive visual impairment,without evidence of cardiac,renal,gastrointestinal,central nervous system or peripheral nervous system *** the surgery,the patient presented with a gray-white dense and thick cotton woollike change in the vitreous body,accompanied by complete retinal ***,hard,free and movable yellow-white deposits were observed in the posterior pole and surrounding retina,the vitreous and subretinal deposits were examined by Congo red staining and immunohistochemical pathological examination,and whole exome sequencing was performed on blood samples from the patient and her ***:During the operation,it was discovered that there was a complete detachment of the retina and a significant amount of hard,free-floating yellow-white deposits were observed beneath the posterior pole and surrounding *** is an exceedingly rare ocular *** examination of the vitreous and subretinal deposit specimens revealed positive Congo red staining,as well as elevated vascular endothelial growth factor(VEGF)expression in vascular endothelial cells within the sediment specimens upon immunohistochemical *** patient and her cousin both exhibited a heterozygous mutation in Glyl03Arg within the transthyretin(TTr)gene,resulting in a substitution of glycine(Gly)at position 103 with arginine(Arg).CONCLUSION:fva.may present with various ocular manifestations,but panretinal detachment is a rare *** cases where retinal detachment persists for an extended period of time,amyloid deposits may form under the retina through retinal tears,leading to subretinal deposits that can impede retinal reattachment and negatively impa

关键词： familial vitreous amyloidosis transthyretin gene Gly103Arg vascular endothelial growth factor

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HArSVErT-fva.列高压变频器在煤矿提升机的应用

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变频器世界 2009年第6期 62-67页

作者：马永健王钢北京利德华福技术有限公司预研部北京利德华福技术有限公司技术工程部

变频改造是矿井提升领域节能、安全技改的主要手段。本文分别对采用绕线式异步电机转子串电阻调速方式和变频调速方式的提升机系统的运行特性进行分析,结合开滦(集团)蔚州矿业公司南留庄煤矿提升机变频改造的现场,介绍提升机系统变频改... 详细信息

变频改造是矿井提升领域节能、安全技改的主要手段。本文分别对采用绕线式异步电机转子串电阻调速方式和变频调速方式的提升机系统的运行特性进行分析,结合开滦(集团)蔚州矿业公司南留庄煤矿提升机变频改造的现场,介绍提升机系统变频改造相关技术,以及HArSVErT-fva.列能量回馈型高压变频器在矿井提升系统上的应用情况。

关键词：矿井提升机高压变频器矢量控制能量回馈

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基本型间歇性外斜视手术成功率的相关因素分析

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中华实验眼科杂志 2019年第2期37卷 101-105页

作者：刘艳丽张伟陈霞马慧芝赵堪兴天津医科大学眼科临床学院 300020 天津市眼科医院天津市眼科研究所天津市眼科学与视觉科学重点实验室300020 天津市宝坻区人民医院眼科 301800

目的探索基本型间歇性外斜视达到功能治愈的相关因素。方法采用前瞻性系列病例观察研究设计。纳入2015年8月至2016年3月在天津市眼科医院行斜视矫正术治疗的基本型间歇性外斜视患者132例,进行术前Newcastle评分、远近Worth 4点灯,术前... 详细信息

目的探索基本型间歇性外斜视达到功能治愈的相关因素。方法采用前瞻性系列病例观察研究设计。纳入2015年8月至2016年3月在天津市眼科医院行斜视矫正术治疗的基本型间歇性外斜视患者132例,进行术前Newcastle评分、远近Worth 4点灯,术前、术后1 d和术后6个月眼位,术前和术后6个月视功能分析仪(fva.远立体视、Frisby Davis Distance(FD2)远立体视和Titmus立体视觉检查图近立体视检查,分析术后6个月眼位成功和立体视重建的影响因素和最佳手术时机的截断点。结果132例患者术后6个月眼位正位者84例,手术成功率为63.6%;欠矫者44例,欠矫率为33.3%;过矫者4例,过矫率为3.0%。术后6个月眼位相关因素的Logistic回归分析结果显示,术后第1天视远斜视角和术前33 cm Worth 4点灯与术后6个月眼位有关(系数b=-0.093,P=0.037;系数b=0.725,P=0.017),术前33 cm Worth 4点灯和术后6个月眼位受试者工作特征(rOC)曲线分析结果显示,rOC曲线下面积为0.645,说明术前33 cm Worth 4点灯结果对术后6个月眼位分析诊断价值较低;术后第1天眼位在0^+10 PD的72例患者术后6个月眼位均获得成功。术后眼位矫正成功和失败患者fva.立体视分布比较,差异有统计学意义(χ2=4.036,P=0.045);Logistic回归分析结果显示,发病年龄和术前6 m FD2远立体视与术后fva.立体视均相关(系数b=-0.213,P=0.023;系数b=0.021,P=0.036)。rOC曲线分析结果显示,发病年龄、术前6 m FD2测量的远立体视曲线下面积分别为0.257和0.752,前者无诊断价值,后者诊断价值中等,最佳截断点是22.5″。结论术后第1天眼位影响术后眼位成功率;术后第1天的理想眼位是0^+10 PD;术后远立体视可明显改善,6 m FD2远立体视下降至22.5″之前行手术治疗可提高术后功能治愈率。

关键词：外斜视/手术眼外肌/手术双眼视立体视

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三个汉族家系玻璃体淀粉样变性患者临床特征及玻璃体切割手术后并发症观察

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中华眼底病杂志 2021年第11期37卷 865-871页

作者：冯燕兵翁文庆和艳艳马桢一石彦波吴轶波朱懿行沈志新浙江中医药大学附属嘉兴中医院眼科嘉兴市眼科医院 314000 浙江中医药大学附属嘉兴中医院病理科 314000 浙江中医药大学附属嘉兴中医院中心实验室嘉兴市糖尿病血管病变研究重点实验室 314000 浙江中医药大学第三临床医学院杭州310053

目的观察家族性玻璃体淀粉样变性(fva.患者临床特征及玻璃体切割手术(PPV)疗效和并发症发生情况。方法回顾性临床研究。2009年6月至2020年3月于嘉兴市中医院眼科检查确诊并接受PPV治疗的3个fva.系的18例患者32只眼纳入研究。其中,男性1... 详细信息

目的观察家族性玻璃体淀粉样变性(fva.患者临床特征及玻璃体切割手术(PPV)疗效和并发症发生情况。方法回顾性临床研究。2009年6月至2020年3月于嘉兴市中医院眼科检查确诊并接受PPV治疗的3个fva.系的18例患者32只眼纳入研究。其中,男性12例22只眼,女性6例10只眼。平均发病年龄(42.28±3.25)年;平均病程(3.75±3.93)年。患眼均行最佳矫正视力(BCVA)、B型超声检查。BCVA检查采用对数视力表进行,记录时换算为最小分辨角对数(logmar)视力。患眼平均logmar BCVA为1.72±0.53;眼压均C(***103Arg)错义突变。PPV中发现周边视网膜出血灶4只眼(12.5%,4/32)、视网膜裂孔5只眼(15.6%,5/32)、视网膜变性灶4只眼(12.5%,4/32)、视网膜脱离3只眼(9.4%,3/32)。玻璃体填充C3F8、硅油分别为2、1只眼。手术后6个月,患眼logmar BCVA为0.39±0.32;与手术前比较,视力明显提高,差异有统计学意义(t=15.131,P=0.000)。手术后发生高眼压2只眼(6.3%,2/32)、继发性青光眼1只眼(3.1%,1/32)、视网膜脱离2只眼(6.3%,2/32)、新生血管性青光眼(NVG)2只眼(6.3%,2/32)、白内障10只眼(31.3%,10/32)。结论fva.眼玻璃体呈灰白色致密、浓稠絮状改变,附着于晶状体后囊呈"足盘"样混浊;PPV治疗可有效提高患眼BCVA;手术后可发生继发性青光眼、继发性视网膜脱离、NVG等。

关键词：淀粉样变性前白蛋白玻璃体切除术手术后并发症

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Design Optimization of Shell and Tube Heat Exchanger by Vibration Analysis

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Modern Mechanical Engineering 2011年第1期1卷 6-11页

作者： S. H. Gawande A. A Keste L. G Navale M. r Nandgaonkar V. J Sonawane U. B Ubarhande Department of Mechanical Engineering Modern Education Society’s College of Engineering Pune India

In this paper a simplified approach to optimize the design of Shell Tube Heat Exchanger [STHE] by flow induced vibration analysis [fva. is presented. The vibration analysis of STHE helps in achieving optimization in design by prevention of tube failure caused due to flow induced vibration. The main reason for tube failure due to flow induced vibration is increased size of STHE. It is found that in case of increased size of STHE, the surface area and number of tubes increases, thus the understanding and analysis of vibration becomes a very difficult task. Again it is found that flow induced vibration analysis is considered as an integral part of mechanical & thermal design of STHE. The detailed design, fabrication, testing and analysis work was carried out at Alfa Laval (India), Ltd., Pune-10.

关键词： Heat Exchanger Flow-Induced Vibration TEma HTrI

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连续性功能性视力测定系统在干眼症中的应用

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世界核心医学期刊文摘（眼科学分册） 2005年第7期1卷 7-7页

作者： Ishida r. Kojima T. Dogru M. 陈立军 Department ofOphthalmology TokyoDentalCollege5- 11- 13 Sugano Ichikawa- shi Chiba 272- 8513 Japan

Purpose: To evaluate the efficacy of a new continuous functional visual acuity measurement (fva.) system for the assessment of dry eye patients. Design: Prospective comparative study. Methods: Monocular recognition acuity measured continuously by the fva. system during a 30- second blinkfree period was defined as functional visual acuity (fva.. Examinations using the fva. system were conducted in 35 eyes of 20 healthy controls and 19 eyes of 13 dry eye patients. Tear function examinations including the Schirmer test, tear film break- up time, and fluorescein and rose Bengal staining were performed in all subjects. Functional visual acuity and tear functions were also examined before and after insertion of punctumplugs in dry eye patients. Functional visual acuity results at 10, 20, and 30 seconds were compared. results: Functional visual acuity in dry eyes were significantly lower than control subjects at all time points (P r punctum plugs insertion improved significantly at all time points (P fva. system seemed not only to be an effective tool in the assessment of dynamic visual acuity changes in dry eye and normal subjects but in evaluating the outcome of management of dry eye disease by punctum plugs.

关键词：功能性视力泪膜破裂时间荧光素染色泪点系统测定动态视力功能检测识别力评价方法连续测定

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