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MHD and kinetic analysis of flow bursts in the Earth's plasma sheet

Science China(Technological Sciences) 2014年第1期57卷 55-66页

作者： ma YuDuan CAO JinBin FU HuiShan REME H. DANDOURAS i. YANG JunYing WANG ZhiQiang TAO Dan YANG Jian School of Astronautics Beihang University SOA Key Laboratory for Polar Science Polar Research Institute of China University of Toulouse UPS-OMP IRAP Toulouse 31028 France The French National Centre for Scientific Research The Research Institute in Astrophysics and Planetology BP 44346F-31028 Toulouse cedex 4 France Nanjing University of Aeronautics and Astronautics

in an attempt to study the flow bursts in the Earth＇s plasma sheet we select an event that took place on August 7, 2004 in the expansion phase of a substorm, using data from the geomagnetic index, solar wind data, plasma and magnetic field observa- tions from C1 Cluster satellite （the Cluster mission has 4 satellites） and from Double Star TC-1 satellite. in MHD approach, TC-1 firstly observed the tailward flow, then the earthward, and finally the flow altemated in two directions. C1 firstly ob- served the earthward plasma flow, and then the tailward plasma flow. Before flow bursts are observed by TC-1 and C1, there are disturbances in local entropy with their tailward local entropy larger than those of the earthward. The kinetic features of the plasma flow observed by C1 are similar to those in MHD. However, kinetic characteristics of the plasma flow observed by TC-1 are far more than the description in MHD. The inadequacy mainly exists in two cases：（i） the firstly enhanced tailward flows given in MHD are found without significant increase of the energetic tailward flux; （ii） the almost stagnant flow in MHD is composed of the enhanced energetic ion flux in both earthward and tailward directions. The earthward flow burst observed by TC-1 might be multiple overshoots and rebounds. The earthward flow burst observed by C1 might be simply rebounded in the near-Earth. The pulsation observed by C1 is earlier than that observed by TC-1 with the former intensity less than that of the latter. After the energetic ion flux in the tailward direction is significantly enhanced, the power spectrum intensity of the ULF wave commences to increase obviously, which may suggest that the stream instability is closely correlated with ULF pulsations.

关键词： MHD kinetic flux entropy

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Spatial heterogeneity and population risk analysis of cotton bollworm, Helicoverpa armigera, in ChinaKey words spatial characteristics, spatial pattern, semivariance, population management, geostatistics, Helicoverpa armigera, population regulation

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insect Science 2005年第4期12卷 255-262页

作者： SHAO-KUi GE RAYMOND i. CARRUTHERS ZU-FEi ma GUANG XUEZHANG DiAN-MO Li State Key Laboratory of integrated management of Pest insects and Rodents Institute of Zoology Chinese Academy of SciencesBeijing China USDA-ARS Exotic & Invasive Weeds Research Unit Albany California US

in this study, semivariance was used to quantitatively measure the spatial heterogeneity for the egg population of cotton bollworm during a growing season. The typical characteristic parameters of theoretical semivariance models against lag distances were applied to measure components of spatial heterogeneity： trend, range, spatial dependence, and the strength of spatial dependence. Then, kriging interpolation was used to evaluate the population risk of cotton bollworm exceeding economic thresholds. From early June through early September, the population densities were sampled 10 times in the study field. Results showed that the spatial patterns were related to population density. For its low-density population, the spatially heterogeneous trends were usually of spherical shapes; but for highdensity ones, the trends shifted to Gaussian shapes. The spatial dependence appeared at varied distances ranging from 52 meters to 936 meters, and the spatial dependence was in the range of 0.39-288.60, which changed with population densities. While having high heterogeneity, the strength of spatial dependence became much stronger. Results of population risk analysis showed that there was a high risk during its early stages, especially in mid-June. in August, population risk was so low that it did not need to be controlled.

关键词： spatial characteristics spatial pattern semivariance population management geostausucs Helicoverpa armigera population regulation

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GATA-3-Not Just for Th2 Cells Anymore

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Cellular & Molecular immunology 2007年第1期4卷 15-29页

作者： i-Cheng Ho Sung-Yun Pai Division of Rheumatology Immunology and Allergy Department ofMedicine Brigham and Women＇s Hospital Harvard Medical SchoolBoston MA 02115 USA Department of Pediatric Hematology-Oncology Children＇s Hospital Bostonand Dana-Farber Cancer Institute Harvard Medical School Boston MA02115 USA

GATA-3 was first cloned as a T cell specific transcription factor in 1991 and its importance in the transcriptional control of T helper type 2 cell （Th2） differentiation was established in the mid to late 90＇s. A role for GATA-3 during thymic development has long implied by its continuous and regulated expression through out T lineage development, but the absolute requirement for GATA-3 during early T lymphoid commitment/survival previously precluded definitive answers to this question. Several technical breakthroughs have fueled fruitful investigation in recent years and uncovered unexpected and critical roles for GATA-3 in CD4 thymocyte survival, invariant natural killer T cell generation and function, and also in beta selection. Not only does GATA-3 participate in nearly every stage of T cell development from common lymphoid progenitor to Th2, conditional knockout studies have indicated that the influence of GATA-3 also extends beyond the immune system. Cellular ＆ Molecular immunology. 2007; 4（1）： 15-29.

关键词： GATA-3 T cell transcription factor thymocyte

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Recent advances in exploring new blood-based biomarkers for the early diagnosis of gastric cancer

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Science China Chemistry 2025年第1期 35-45页

作者： Xinyu Peng Qian ma Da Han School of Life Science Shanghai University institute of Molecular Medicine Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine State Key Laboratory of Oncogenes and Related Genes Renji Hospital School of Medicine Shanghai Jiao Tong University Department of Research and Development Intellinosis Biotechnologies Co.Ltd.

Gastric cancer(GC) is a prevalent and lethal ma.ignancy worldwide, and the 5-year survival rate is less than 30%. The absence of distinctive symptoms often leads to late-stage diagnosis, contributing to a grim prognosis. Early detection is pivotal for improving the survival rates and outcomes of GC patients. Traditional diagnostic methods, including gastroscopy and histopathological examination, are restricted in the early diagnosis of GC. Conventional protein biomarkers, such as carcinoembryonic antigen(CEA), carbohydrate antigen 19-9(CA19-9), and carbohydrate antigen 72-4(CA72-4), exhibit insufficient sensitivity and specificity for GC screening, which diminishes their clinical value. Recently, novel circulating biomarkers, such as circulating tumor cells(CTCs), circulating tumor cell DNA(ct DNA), and circulating free RNA(cf RNA), have emerged as promising candidates in the burgeoning field of liquid biopsy due to their superior sensitivity and specificity. This review focuses on the latest research on blood-based biomarkers for GC diagnosis and examines the clinical potentials and challenges associated with these emerging biomarkers.

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Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-βpathway

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Signal Transduction and Targeted Therapy 2020年第1期5卷 1732-1743页

作者： Xiaoxue Yang Liping ma Rong Wei Tinghong Ye JianKang Zhou maoyao Wen Ruoting Men Rami i.Aqeilan Yong Peng Li Yang Department of Gastroenterology&Hepatology West China HospitalSichuan UniversityChengdu 610041China State Key Laboratory of Biotherapy and Cancer Centre West China HospitalSichuan Universityand Collaborative Innovation Centre for BiotherapyChengdu 610041China School of Bioscience and Technology Chengdu medical collegeChengdu 610500China Department of immunology&Cancer Research Hebrew University-Hadassah Medical SchoolJerusalemIsrael

The activation of hepatic stellate cells(HSCs)participates in liver fibrosis,and emerging evidences indicate that microRNAs(miRNAs)are abnormally expressed during HSC ***,the potential roles of miRNAs in liver fibrosis still remain ***,this study aimed to investigate the role of miR-199a-3p in liver fibrosis and its underlying *** found that miR-199a-3p expression was drama.ically upregulated during HSC activation in vitro,and during liver fibrogenesis in CCl4-treated rats,and its liver expression was increased in the patients with *** the luciferase assay and RT-qPCR,we revealed that the expression of miR-199a-3p in HSCs was driven by the transcription factor Twist1 which could be further induced by TGF-β*** studies showed that inhibition of miR-199a-3p in both human LX2 cells and rat HSCs significantly decreased the expression of fibrotic markers,such as fibronectin and connective tissue growth factor(CTGF),whereas the forced expression of miR-199a-3p exhibited opposite effects,demonstrating the role of miR-199a-3p in promoting HSC ***,miR-199a-3p plays an important role in TGF-βsignalling pathway activation through targeting CAV2 that negatively regulates the expression of transforming growth factor-beta receptor type i(TGFβRi).importantly,administration of antagomiR-199a-3p in the CCl4-treated mice significantly ameliorated hepatic *** conclusion,Twist1-induced miR-199a-3p mediates the activation of HSCs by suppressing CAV2 expression and subsequently increasing TGFβRi expression to promote TGF-β*** findings highlight the therapeutic potential of miR-199a-3p for hepatic fibrosis.

关键词： Twist1 miR hepatic

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Upward organelle motility

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Journal of integrative Plant Biology 2015年第1期57卷 2-3页

作者： Tobias i.Baskin Centre for Plant integrative Biology University of NottinghamUK Biology Department University of Massachusetts Amherst MA USA Professor Special Issue Editor

Eukaryotic cells contain a collection of membrane-bounded organelles, in addition to the nucleus, supporting the large size and diverse activities of this type of cell. Evolving with these compartments are filaments and enzymes that convert chemical energy into work （so-called motor proteins）, a network collectively termed the cytoskeleton. Whether it is a chloroplast moving to optimally intercept light or the endoplasmic reticulum deploying its cisternae to deliver secreted proteins, motility of organelles is an essential component of their function, and this motility is driven by the cvtoskeleton.

关键词： Upward organelle motility cell

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不同类型学业压力对不同年级高中生执行功能子成分的影响

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心理学报 2025年第1期57卷 18-35页

作者：马超汪彦云付军军赵鑫甘肃省行为与心理健康重点实验室西北师范大学心理学院兰州730070

选取985名高一~高三年级的学生,采用相关分析和结构方程模型等方法考察了学业压力4个子维度在不同年级高中生各执行功能成分中的作用。结果发现,随着高中生年级的升高,父母压力和教师压力对各执行功能成分的负向预测作用逐渐增强,社交... 详细信息

选取985名高一~高三年级的学生,采用相关分析和结构方程模型等方法考察了学业压力4个子维度在不同年级高中生各执行功能成分中的作用。结果发现,随着高中生年级的升高,父母压力和教师压力对各执行功能成分的负向预测作用逐渐增强,社交压力对各执行功能成分的负向预测作用逐渐减弱。相比之下,自我压力对高中生的干扰抑制、反应抑制和注意转换能力均显示出了正向预测作用,并随年级的升高而增强。这表明,不同类型学业压力对各执行功能成分的预测作用存在差异,并将随高中生年级的升高而发生变化。本研究所产生的结论对于教育工作者有效制定高中生学业压力应对策略具有重要的启示意义。

关键词：执行功能学业压力高中生结构方程模型

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Petrogenesis of granitic rocks of the Jabal Sabir area,South Taiz City,Yemen Republic

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Chinese Journal Of Geochemistry 2011年第2期30卷 193-203页

作者： Rasmy i.El-Gharbawy Department of Geology Faculty of ScienceAin Shams UniversityCairoEgypt

The Tertiary granitic intrusive body(～21 ma) of the Jabal Sabir area was emplaced during the early stages of the Red Sea *** intrusive body occupies the southern sector of Taiz *** is triangular in shape,affected by two major faults,one of which is in parallel to the Gulf of Aden,and the other is in parallel to the eastern margin of the Red Sea *** petrogenesis of such a type of intrusion provides additional informa.ion on the origin of the Oligo-Miocene magma.ic activity in relation to the rifting tectonics and evolution of this part of the Arabian *** granitic body of Jabal Sabir belongs to the alkaline or peralkaline suite of A-type *** is enriched in the *** tight bundle plot of its REE pattern reflects neither tectonism nor *** granite body is characterized by high alkali(8.7%-10.13%),high-field strength elements(HFSE),but low Sr and Ba and high Zn *** abundance of xenoliths from the neighboring country rocks and prophyritic texture of the Jabal Sabir granite body indicate shallow depths of *** major and trace elements data revealed a fractional crystallization origin,probably with small amounts of crustal *** is interpreted that the Jabal Sabir intrusion represents an anorogenic granite pertaining to the A-type,formed in a within-plate environment under an extensional tectonic setting pertaining to rift-related granites.

关键词： A 类型花岗石也门共和国阿拉伯的努比亚的盾红海 rifting 在内板花岗石

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The giant Jiaodong gold province： The key to a unified model for orogenic gold deposits？

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Geoscience Frontiers 2016年第3期7卷 409-417页

作者： David i.Groves M.Santosh Centre for Exploration Targeting UWA Cmwley 6009 WA Australia Centre for Tectonics Resources and Exploration Department of Earth Sciences University of Adelaicle SA 5005 Australia State Key Laboratory of Geological Processes and Mineral Resources China University of Geosciences Beijing 100083 China Division of interdisciplinary Science Faculty of Science Kochi University Kochi 780-8520 Japan

Although the term orogenic gold deposit has been widely accepted for all gold-only lode-gold deposits,with the exception of Carlin-type deposits and rare intrusion-related gold systems,there has been continuing debate on their *** syngenetic models and hydrothermal models dominated by meteoric fluids are now clearly ***-hydrothermal models fail to explain the genesis of orogenic gold deposits because of the lack of consistent spatially- associated granitic intrusions and inconsistent temporal *** most plausible,and widely accepted,models involve metamorphic fluids,but the source of these fluids is hotly *** within deeper segments of the supracrustal successions hosting the deposits,the underlying continental crust,and subducted oceanic lithosphere and its overlying sediment wedge all have their *** orogenic gold deposits of the giant Jiaodong gold province of China,in the delaminated North China Craton,contain ca.120 ma gold deposits in Precambrian crust that was metamorphosed over 2000 million years prior to gold *** only realistic source of fluid and gold is a subducted oceanic slab with its overlying sulfide-rich sedimentary package,or the associated mantle *** could be viewed as an exception to a general metamorphic model where orogenic gold has been derived during greenschist- to amphibolite-facies metamorphism of supracrustal rocks：basaltic rocks in the Precambrian and sedimentary rocks in the ***,if a holistic view is taken,Jiaodong can be considered the key orogenic gold province for a unified model in which gold is derived from late-orogenic metamorphic devolatilization of stalled subduction slabs and oceanic sediments throughout Earth *** latter model satisfies all geological,geochronological,isotopic and geochemical constraints but the precise mechanisms of auriferous fluid release,like many other subduction-related processes,are model-driv

关键词： Jiaodong province Orogenic gold Metamorphic fluids Subduction zones Tectonics

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Transition from oceanic subduction to continental collision:insights from volcanogenic-sedimentary rocks of the Tannuola terrane(northern Central Asian Orogenic Belt)

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Geoscience Frontiers 2024年第4期15卷 41-60页

作者： E.V.Vetrov N.i.Vetrova V.S.Sobolev institute of Geology and Mineralogy SB RAS Koptyuga ave.3NovosibirskRussia

magma.ism associated with oceanic subduction plays a dominant role in crustal growth during the Earth's *** Tannuola terrane,situated in the northern Central Asian Orogenic Belt(CAOB),is a key area to understanding oceanic subduction and initial collision processes in the northern *** order to investigate the switch from subduction to collision settings,detailed field mapping,zircon SHRiMP U-Pb geochronological and whole-rock geochemical studies of volcanogenic-sedimentary rocks from the Tannuola terrane were carried *** U-Pb ages indicate multi-stage volcanism lasted at least 30 ma from~540 to~510 ma,that can be divided into three events:the late Ediacaran(before~540 ma),the early Cambrian(~520 ma)and the middle Cambrian(~510 ma).These ages are inter-preted to the initial,main and final stages of oceanic subduction during the late Proterozoic-early *** the late Ediacaran,tholeiitic basalts with highεNd(t)values(from+7.4 to+8.5)were *** forming by the 10%-30%partial melting of spinel-garnet mantle source during slab *** the early Cambrian,transitional from tholeiitic to calc-alkaline basaltic rocks withεNd(t)value(+5.6)and coeval intermediate-felsic volcanic rocks with similarεNd(t)values(+5.9 and+6.5)*** early Cambrian basaltic rocks are interpreted to be derived by 10%-30%partial melt-ing of a depleted mantle source metasoma.ized by slab-derived fluids released from the subducting ocea-nic *** middle Cambrian calcalkaline basaltic rocks withεNd(t)value of+6.2 might be emplaced as a result of low(5%-10%)degree partial melting of a metasoma.ized mantle followed by fractional crys-tallization of clinopyroxene and *** intermediate-felsic volcanic rocks withεNd(t)values from+6.0 to+6.8 were formed through fractionation of the juvenile Neoproterozoic *** middle Cambrian volcanism is interpreted to be triggered by the slab break-off during the transition to a collisional se

关键词： island-arc magma.ism Ediacaran Cambrian zircon U-Pb dating Nd isotopes Central asian orogenic belt

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