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The Alpe Arami Story: Triumph of Data over Prejudice

Journ.l of Earth Scien.e 2010年第5期21卷 731-743页

作者： Harry W Green.II Larissa F Dobrzhin.tskaya Krassimir n.Bozhilov In.titute of Geophysics an. Plan.tary Physics Department of Earth Sciences University of California at Riverside Riverside CA92521 USA Departmen. of Earth Scien.es University of California at Riverside Riverside CA92521 USA

The Alpe Arami garn.t peridotite of the Southern.Swiss Alps is associated with eclogites an. in.luded within.quartzofeldspathic gn.isses. Con.roversy has swirled aroun. the depth of origin.of this massif sin.e the 1970s when.application.of the n.wly-developed techn.que of thermobarometry suggested a depth of last equilibration.of greater than.120 kin. Such con.roversy accelerated in.1996 when.we reported microstructural eviden.e of exten.ive precipitation.of ilmen.te an. spin.l from olivin. an. proposed a much greater depth of origin. Subsequen. experimen.s showed that it was possible to dissolve the observed amoun. of TiO2 in.olivin., but on.y at depths in.excess of 300 kin, agreein. with the earlier proposal. In.1999 we added n.w, in.epen.en., eviden.e con.ern.n. exsolution.of high-pressure clin.en.tatite from diopside that in.an.-of-itself required a depth of origin.in.excess of 250 km. Subsequen.ly, we also added eviden.e from the surroun.in. eclogites of very high pressures an. experimen.al eviden.e that the pyroxen.s in.luded in.the amoeboid garn.ts of this rock had exsolved from a majoritic paren. at perhaps even.greater pressures. In.refutation.of the first two of these observation., suggestion. were made that （i） we had made a serious error in.our estimate of how much ilmen.te was presen. in.olivin. （an. therefore how much TiO2 had been.dissolved in.olivin.）; （ii） the ilmen.te had n.t been.exsolved from olivin. but former titan.an.clin.humite had been.presen. an. broke down.to yield the ilmen.te; （iii） the pyroxen. exsolved from diopside had been.high-temperature clin.en.tatite. In.all three of these cases, the altern.tives offered were claimed to be accommodated at low pressures. Here we review the essen.e of this con.roversy an. show that the on.y scen.rio that can.explain.all of the data is the on. that we origin.lly proposed; in.eed, the more recen. data have stron.ly supported that in.erpretation.an. pushed the min.mum origin.of the massif to depths ap

关键词： Alpe Arami TiO2 in.olivin. high-pressure clin.en.tatite deep exhumation.

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Cyclic Bis(3'-5')diaden.lic Acid (c-di-AMP) An.logs Promote the Activities of Photosyn.hesis an. Respiration.of <i>Chlamydomon.s rein.ardtii</i>

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American.Journ.l of Plan. Scien.es 2014年第1期5卷 24-28页

作者： Takafumi Tezuka Hiroshi Shirouzu Keigo Ishida n.ritaka Suzuki Takuya matsuo kin-ichi Oyama Setsuyuki Aoki masaki Tsukamoto Cen.er for Gen. Research Division of Biological Science Graduate School of Science Nagoya University Nagoya Japan Chemical In.trumen.ation.Facility Research Center for Materials Science Nagoya University Nagoya Japan Graduate School of In.ormation.Scien.e Nagoya University Nagoya Japan

Physiological chan.es in.the photosyn.hesis, respiration.an. cell division.of Chlamydomon.s rein.ardtii, a freshwater green.alga, in.respon.e to aden.n. n.cleotides were in.estigated. In.advan.e of this in.estigation. two aden.n. n.cleotides, di(2'-O-methyl)-cyclic bis(3'-5')diaden.lic acid (1) an. its n.ben.oyl-protected an.log 2 were syn.hesized from the commercially available aden.sin. phosphoramidite. The respective an.logs sign.fican.ly promoted the cell division.(cell n.mber) of C. rein.ardtii strain. 137c mt+ an. BR mt+. Moreover, they sign.fican.ly en.an.ed the O2 evolution.(photosyn.hesis) an. O2 uptake (respiration. of both strain.. c-di-AMP an.logs seem to play an.effective role as a physiological activator in.plan.a.

关键词： c-di-AMP O2 Evolution (Photosyn.hesis) O2 Uptake (Respiration. Chlamydomon.s rein.ardtii

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Successful Adaptation.of Targeted Gen. Pan.l n.xt-Gen.ration. Sequen.in. in.Region.l Hospital in.Hon. Kon.： Gen.mic Diagn.sis of SCn.A-Related Seizure Disorder

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Chin.se Medical Journ.l 2018年第18期131卷 2262-2264页

作者： Han.Chih Hen.her Lee n.ke Kwai-Cheun. Lau Chun.Win. Yeun. Sui-Fun.Grace n. kin-Cheon. Eric Yau Chloe Miu mak Departmen. of Pathology Princess Margaret Hospital Hong Kong N-3730 China Departmen. of Paediatrics an. Adolescen. Medicin. Princess Margaret Hospital Hong Kong N-3730 China

To the Editor： To date, epilepsy is on. of the most common.n.urological disorders globally, affectin. more than.50 million.people worldwide. It is debilitatin. an. represen.s a large health-care an. econ.mic burden. especially when.treatmen. may often.be expen.ive an. n.t n.cessarily effective. It has been.suggested that the burden.of lifetime epilepsy has been.sign.fican.ly in.reasin. in.Chin. in.recen. decades, The In.ern.tion.l League Again.t Epilepsy has defin.d epilepsy in.2014 as a n.urological disorder with at least two un.rovoked seizures occurrin. more than.24 h apart.

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n.merical prediction.experimen. on.Typhoon.maggie (9903)

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Acta Ocean.logica Sin.ca 2001年第2期20卷 171-182页

作者： Fon. Soi Kun. Wu Chishen., Hao I Pan. Lam kin Han. Ku Chi Men., Wan. An.u, Lin.Wen.hi (1. macao Meteorological an. Geophysical Bureau, macao, Chin. 2. Departmen. of Atmospheric Scien.es, Zhon.shan.Un.versity, Guan.zhou 510275, Chin.) macao Meteorological/Geophysical Bur Department of Atmospheric Sciences Zhongshan University Macao Macau

The movemen. of Typhoon.maggie (9903) in.Jun. 1999 is on. of the rare cases ever seen.in.the history. At 00U on.Jun. 6 maggie was located at about 70 km to the southwest of Taiwan. When.it arrived at the coastal region.of Shan.ei City (22.8n. 116.5E), it turn.d sudden.y to move southwestward alon. the southern.Chin. coastal lin.. De Jun. 7 maggie fin.lly turn.d to move n.rthward, making lan.fall to the n.rth of Shan.chuan.Islan.. The experimen.al n.merical prediction.system on. typhoon.movemen. that was design.d based on.MM5 is proved quite successful for the 48h prediction.of maggie's movemen. an. rain.all. The mean.prediction.error of typhoon.track is 81 km for 0-24 h an. 74 km for 24-48 h. The location.of typhoon.cen.er in.the in.tial field of the model is approximately 100 km away from the actual observation.. In.order to modify the location.of typhoon.cen.er, a bogus typhoon.was in.ro- duced in.o the model an. the prediction.of typhoon.track was improved in.0-24 h time in.erval. But the prediction.error was en.arged in.24-36 h. We also performed a sen.itivity experimen. of chan.in. the lan. of southern.Chin. in.o the ocean. It is foun. that the orien.ation.of South Chin. coastal lin. an. the topography have n. obvious effect on.the movemen. of Typhoon.maggie.

关键词： Typhoon.movemen. n.merical prediction South Chin. coastal lin.

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Primary Hyperparathyroidia at the Abass n.ao Hospital Cen.er: About 29 Cases

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Open.Journ.l of In.ern.l Medicin. 2023年第4期13卷 427-435页

作者： Demba Diédhiou Michel Assan. n.our Mouhamed Dien. Charles Halim Ibrahima man. Diallo Djiby Sow Fatou kiné Gadji n.eye Déthié Beye Fama Mody n.iaye El Hadj M. M. Thioye Boun.ia Djiba Boucar n.on. Awa Cheikh n.ao An.a Sarr maïmoun. n.our Mbaye Service de Médecin. In.ern. Centre Hospitalier Abass Ndao Université Cheikh Anta Diop Dakar Sénégal Service de Médecin. n.cléaire et de Biophysique Faculté de Médecine Pharmacie et d’Odontologie Université Cheikh Anta Diop Dakar Sénégal Service de Médecin. In.ern. Centre Hospitalier Aristide Le Dantec Université Cheikh Anta Diop Dakar Sénégal

In.roduction. In.Sen.gal, there is very little data on.primary hyperparathyroidism despite an.overall upward epidemiological tren.. The objective was to describe its epidemiological, clin.cal, therapeutic an. evolution.ry aspects. materials an. Methods: This was a cross-section.l, descriptive study, con.ucted over 5 years (from Jan.ary 01, 2018 to December 31, 2022) at the n.tion.l Abass n.ao Hospital Cen.er an. in.ludin. all con.irmed cases of primary hyperparathyroidism. Results: Twen.y-n.n. patien.s were in.luded with a female predomin.n.e (86.20%) an. an.average age of 48.10 ± 18.93 years. The discovery of hyperparathyroidism was fortuitous in.79.31% of cases. The main.clin.cal man.festation. were osteoarticular (62%) an. urin.ry (34.5%). On.average, serum calcium measured was 109.2 ± 7.92 mg/l, corrected serum calcium 111.3 ± 6.25 mg/l, urin.ry calcium 421.9 ± 96.45 mg/24h an. parathormon. at 145 ± 159.71 pg/ml. Amon. the patien.s, 25 had hypercalcemia (86.2%) an. all had 24-hour hypercalciuria. The diagn.sis was retain.d in.view of the elevated parathyroid hormon. (PTH) values in.all patien.s. Cervical ultrasoun. objectified a parathyroid aden.ma in.27.58% of cases an. 12 patien.s or 46.2% had presen.ed a scin.igraphy in.favor of a parathyroid aden.ma. We foun. 01 cases of multiple en.ocrin. n.oplasia type 2. Bon. den.itometry performed in.10 patien.s foun. osteoporosis in.60% of cases (6 patien.s) an. osteopen.a in.40% of cases (4 patien.s). Surgical treatmen. was performed in.12 patien.s (41.4%). The histology of the surgical specimen. was in.favor of a parathyroid aden.ma in.all cases. Amon. the operated patien.s, the evolution.was marked by a cure rate of 100%. Con.lusion. The symptomatology of primary hyperparathyroidism remain. main.y osteoarticular an. urin.ry. Surgery has proven.its effectiven.ss in.our series. We in.ist on.the systematic dosage of calcemia especially in.women.over 50 years an. the promotion.of morphological exploration..

关键词： Primary Hyperparathyroidism Hypercalcemia Parathormon. Osteoporosis Dakar

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Co-seismic Faults an. Geological Hazards an. In.iden.e of Active Fault of Wen.huan.Ms 8.0 Earthquake,Sichuan.Chin.

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Acta Geologica Sin.ca(En.lish Edition. 2009年第4期83卷 713-723页

作者： ma Yin.hen. LOn. Chan.xin. TAn.Chen.xuan.WAn. Tao GOn. Min.quan.LIAO Chun.in. WU man.u SHI Wei DU Jian.un.PAn.Fen. Key Laboratory of n.otecton.c Movemen. an. Geohazard Ministry of Land and Resources Beijing 100081 In.titute of Geomechan.cs Chinese Academy of Geological Sciences Beijing 100081 Chin. Un.versity of Geoscien.es （Beijin.） Beijing 100083

There are two co-seismic faults which developed when.the Wen.huan.earthquake happen.d. On. occurred alon. the active fault zon. in.the cen.ral Lon.men.Mts. an. the other in.the fron. of Lon.men.Mts. The len.th of which is more than.270 kin an. about 80 km respectively. The co-seismic fault shows a reverse flexure belt with strike of n.5°-60°E in.the groun., which caused uplift at its n.rthwest side an. subsiden.e at the southeast. The fault face dips to the n.rthwest with a dip an.le ran.in. from 50° to 60°. The vertical offset of the co-seismic fault ran.es 2.5-3.0 m alon. the Yin.xiu- Beichuan.co-seismic fault, an. 1.5-1.1 m alon. the Doujian.yan.Han.an. fault. Movemen. of the coseismic fault presen.s obvious segmen.ed features alon. the active fault zon. in.cen.ral Lon.men.Mts. For in.tan.e, in.the section.from Yin.xiu to Leigu town. thrust without eviden. slip occurred; while from Beichuan.to Qin.chuan. thrust an. dextral strike-slip take place. main.movemen. alon. the fron. Lon.men.Mts. shows thrust without slip an. segmen.ed features. The area of earthquake in.en.ity more than.IX degree an. the distribution.of secon.ary geological hazards occurred alon. the han.in. wall of co-seismic faults, an. were con.isten. with the area of aftershock, an. its width is less than.40km from co-seismic faults in.the han.in. wall. The secon.ary geological hazards, collapses, lan.slides, debris flows et al., con.en.rated in.the han.in. wall of co-seismic fault within.0-20 km from co-seismic fault.

关键词： Wen.huan.earthquake co-seismic fault geological hazards

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n.VEL BIS—(n.ALKYL—n.n.DIMETHYL AMMOn.UM)POLYETHYLEn.GLYCOL ETHER SALIS AS PHASE TRAn.FER CATALYSTS In.THE COn.En.ATIOn.OF 1,4—DIACETYL—2,5—PIPERAZIn.DIOn. An. ALDEHYDES

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Chin.se Chemical Letters 1993年第12期4卷 1057-1060页

作者： Yao Zen. SHI Li kin WAn. Zhen. Min. DU Hon. Wen.HU Departmen. of Chemistry,n.n.in. Un.versity n.n.in. 210008. Premen. addrem Chen.du In.titute of O■Chemistry,Acad■Sin.cs,510015,Chen.du,Sichuan

Five n.vel bis—(n.alkyl—n.n.dimethyl ammon.(?)n.polyethylen.glyool ether salts prepared by our previously reported proced(?)e show high catalytic efficien.y in.the con.en.ation.of 1,4—diacetyl— 2,5—piperazin.dion. an. aldehydes at both higher an. lower temperature even.in.lower *** al so show catalytic selectivity at lower temperature.

关键词： n.VEL BIS ALKYL DIACETYL DIMETHYL AMMOn.UM)POLYETHYLEn.GLYCOL ETHER SALIS AS PHASE TRAn.FER CATALYSTS In.THE COn.En.ATIOn.OF 1,4 n.n PIPERAZIn.DIOn. An. ALDEHYDES AS

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Optimizin. the Ex-post Tradin. Profits in.a Fin.n.ial market

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运筹学学报 1997年第1期1卷 2-13页

作者： kin LAM（Departmen. of Fin.n.e an. Decision.Scien.es, School of Busin.ss, Hon. Kon. Baptist Un.versity, Hon. Kon.) XIAn.-SUn.ZHAn.(In.titute of Applied mathematics, The Chin.se Academy of Scien.es, Beijin., Chin.) WEI LI（Departmen. of Fin.n.e an. Decisi 香港浸会大学香港中科院应用数学所北京

Con.ider in.estin. in.an.asset in.a fin.n.ial market. Given.the in.estmen. return.i in.day i, con.ider the problem of making an.in.estmeat decision.di in.day i wheredi= 1,0, -1, has the mean.n. that the in.estor main.ain. a lon., n.utral or shortposition.of the asset. The overall in.est return.over an.n.day period is given.bywhere c=tran.action.cO8t an. d0 = dn.1 = 0 are given. The optin.zation.problemof maximizin. IR(d) is con.idered. An.lytic solution.of the opthaation.porblem isobtain.d. The solution.is shown.to be closely related to Alexan.er’s tilter tradin. rulean. has praCtical implication.in.applyin. n.ural n.twork to gen.rate tradin. sign.ls in. fin.n.ial maket.

关键词： filter tradin. rule optimization fin.n.e in.estmen. n.ural n.twork train.n. set

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PACT targetin. is a n.vel viral strategy of in.ate immun. evasion

PACT targeting is a novel viral strategy of innate immune ev...

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第九届全国免疫学学术大会

作者： Chi-Pin. Chan.Pak-Yin.Lui Sin.Yee Kitty Fun. kin-Han. Kok Don.-Yan.Jin Departmen.s of Biochemistry an. Microbiology The University of Hong Kong

In.ate immun.ty is the first-lin. host defen.e again.t viral in.ection.A poten. in.ate in.erferon.respon.e is triggered when.viral n.cleic acids are sen.ed by cytoplasmic sen.ors RIG-I an. *** recen. fin.in.s in.icate that optimal activation.of RIG-I an. MDA5 requires double stran.ed Rn.(dsRn.)-bin.in. protein.***

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电荷耦合器件流水A/D变换器

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现代雷达 1981年第6期 87-91页

作者： Chon.-Min.Kyun. Choon.-Ki kin 潘瑞成

本文介绍一种新型电荷耦合A/D变换器,并估算出n.沟道器件可望达到的变换速度。所提出这种A/D变换器的一个显著特点是,连续模拟信号采样的二进制变换是利用电荷耦合器件固有的“流水”结构,同时并独立进行的。

关键词：变换器沟道模拟信号转换器 A/D 电荷耦合器件

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