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Feasibility of totally laparoscopic gastrectomy without prophylactic drains in gastric cancer patients

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World Journal of Gastroenterology 2021年第26期27卷 4236-4245页

作者： Hao Liu peng Jin Xu Quan Yi-bin Xie Fu-Hai ma Shuai ma Yang Li Wen-Zhe Kang Yan-Tao Tian Department of Pancreatic and Gastric Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Gastrointestinal Surgery The Second HospitalJilin UniversityChangchun 130041Jilin ProvinceChina

BACKGROUND Prophylactic drains have been used to remove intraperitoneal collections and detect complications early in open *** the last decades,minimally invasive gastric cancer surgery has been performed ***,reports on routine prophylactic abdominal drainage after totally laparoscopic distal gastrectomy are *** To evaluate the feasibility performing totally laparoscopic distal gastrectomy without prophylactic drains in selected *** Data of patients with distal gastric cancer who underwent totally laparoscopic distal gastrectomy with and without prophylactic drainage at China National Cancer Center/Cancer Hospital from February 2018 to August 2019 were *** outcomes between patients with and without prophylactic drainage were *** A total of 457 patients who underwent surgery for gastric cancer were *** these,125 patients who underwent totally laparoscopic distal gastrectomy were *** propensity score matching,data of 42 pairs were *** incidence of concurrent illness was higher in the drain group(42.9%vs 31.0%,P=0.258).The overall postoperative complication rates were 19.5%and 10.6%in the drain(n=76)and no-drain groups(n=49),respectively;there were no significant differences between the two groups(P>0.05).The difference between the two groups based on the need for percutaneous catheter drainage was also not significant(9.8%vs 6.4%,P=0.700).However,patients with a larger body mass index(≥29 kg/m2)were prone to postoperative complications(P=0.042).In addition,the number of days from surgery until the first flatus(4.33±1.24 d vs 3.57±1.85 d,P=0.029)was greater in the drain *** Omitting prophylactic drainage may reduce surgery time and result in faster *** prophylactic drains are not necessary in selected patients.A prophylactic drain may be useful in high-risk patients.

关键词： Gastric cancer Prophylactic drainage Totally laparoscopic gastrectomy Enhanced recovery after surgery Minimally invasive surgery Early gastric cancer

Fe-doped CoP core–shell structure with open cages as efficient electrocatalyst for oxygen evolution

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Journal of Energy Chemistry 2020年第9期29卷 328-333,I0010页

作者： Jing-Yi Xie Zi-Zhang Liu Jia Li Lei Feng Min Yang Yu ma Da-peng Liu Lei Wang Yong-Ming Chai bin Dong College of Science State Key Laboratory of Heavy Oil ProcessingChina University of Petroleum(East China)Qingdao 266580ShandongChina Shandong Key Laboratory of Biochemical Analysis College of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042ShandongChina

Developing a facile approach based on transition metal-based Prussian blue(PB)and its analogues(PBAs)with core-shell nanostructure is a very promising choice for constructing cost-effective electrocatalysts for oxygen evolution reaction(OER).Herein,a bimetallic core-shell structure with open cages of Fe-doped CoP(Fe-CoP cage)has been synthesized using CoFe-PBA cage-4 as precursor through a facile hydrothermal method and following phosphating ***,there is an open hole in each face center of Fe-CoP cage,which suggests the more exposure of active sites for *** measurements show that Fe-CoP cage can afford a current density of 10 ma cm-2 at a low overpotential(300 mV),which is better than that of *** excellent performance can be attributed to Fe doping composition and unique open-cage core-shell *** synergistic effect derived from bimetallic active for OER has been *** its great catalytic stability has been evaluated via 1000 cycles of CV and chronoamperometry *** work provides a potential method to design multiple transitional metal-doping electrocatalysts with complex framework derived from PBAs for water splitting.

关键词： Core-shell structure CoFe-PBA Cation exchange Phosphating Oxygen evolution reaction

Revealing the illumination effect on the discharge products in high-performance Li-O_(2) batteries with heterostructured photocatalysts

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Carbon Energy 2022年第6期4卷 1169-1181页

作者： Hao Gong Tao Wang Kun Chang peng Li Lequan Liu Xingyu Yu bin Gao Hairong Xue Renzhi ma Jianping He Jinhua Ye Department of Chemistry and materials Science College of ScienceNanjing Forestry UniversityNanjingChina Jiangsu Key Laboratory of materials and Technology for Energy Conversion College of Materials Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjingChina TJU-NIMS International Collaboration Laboratory School of Material Science and EngineeringTianjin UniversityTianjinChina International Center for materials Nanoarchitectonics(WPI-maNA) National Institute for Materials Science(NIMS)IbarakiJapan

Aprotic lithium–oxygen batteries(LOBs)have been recognized as novel energy storage devices for their outstanding specific energy density,while the large discharge/charge overpotential is a tough barrier to be ***,hetero-structured MoS_(2)/ZnIn_(2)S_(4) nanosheets have been prepared to capture visible light and the generated charge carriers are utilized for promoting both the oxygen reduction reaction and the oxygen evolution *** the light illumination in the discharge process,the abundant photo-inspired electrons serve as the reaction sites to promote the reduction of O_(2) into LiO_(2) which is finally deposited as Li_(2)O_(2).On the contrary,the generated holes in the valence band can contribute to the low oxidization potential of Li_(2)O_(2) during the charge *** delivers a low charge potential of 3.29 V,with an excellent resulting energy efficiency of 96.7%,much superior to that of 69.2%in the dark *** is noted that the involvement of photoelectrons has influenced the growth of Li_(2)O_(2) films on the MoS_(2)/ZnIn_(2)S_(4) nanosheets through the surface-adsorption *** insights from the theoretical calculation confirm that the photoelectrons favor the absorption of LiO_(2) and the formation of the Li_(2)O_(2) film through the surface ***,this paper provides a deeper understanding of the mechanism of photoinspired charge carriers in LOBs and will enable further exploration of photo-involved energy storage systems.

关键词： bifunctional catalysts Li-O_(2)battery overpotential surface-route growth theoretical calculation

A Fragment Substitution in Promoter of MS92/PTC1 Causes male Sterility in Rice

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Rice science 2020年第5期27卷 396-404,I0018-I0023页

作者： Qin peng Deng Luchang Chen Weilan Huang Juan Fan Shijun Tu bin Tan Jun Yuan Hua Wang Yuping ma bingtian Li Shigui Rice Research Institute/State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengdu 611130China Crop Research Institute Sichuan Academy of Agricultural SciencesChengdu 610066China Characteristic Crop Research Institute Chongqing Academy of Agricultural SciencesChongqing 402160China

Persistent tapetal cell1(PTC1) plays a curial role in pollen development, and is thought to function as a transcriptional activator in rice. However, the molecular mechanism of PTC1 in regulating pollen development and its cis-elements are not well understood. We identified a novel weak male sterility mutant(ms92) which exhibited expanded tapetum and shrink pollen grains. map-based cloning and allelic analysis suggested that the male sterility of ms92 was caused by a DNA fragment substitution in the promoter of PTC1. The decreased expression of MS92/PTC1 in ms92 and cis-element analysis indicated that the substituted sequence contained several potential binding cis-element of negative feedback. MS92/PTC1 was specifically expressed in tapetum and microspores at the young microspore stage, and its protein was localized in nucleus. We further found that MS92/PTC1 functions as a transcription activator by recognizing H3K4me3. Transcriptomic analysis revealed that a number of genes involved in tapetum degeneration and pollen wall formation were down-regulated in ms92, which are the potential targets of MS92/PTC1. The substitution fragment in MS92/PTC1 promoter was essential for pollen development, and we provided a novel mutant for further identifying the cis-elements in promoter and the molecular network of MS92/PTC1.

关键词： rice MS92/PTC1 plant homeodomain finger cis-element male sterility anther

Feasibility and nutritional impact of laparoscopic assisted tailored subtotal gastrectomy for middle-third gastric cancer

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World Journal of Gastroenterology 2020年第43期26卷 6837-6852页

作者： Hao Liu peng Jin Fu-Hai ma Shuai ma Yi-bin Xie Yang Li Wei-Kun Li Wen-Zhe Kang Yan-Tao Tian Department of Pancreatic and Gastric Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Gastrointestinal Surgery The Second HospitalJilin UniversityChangchun 130041Jilin ProvinceChina Department of Pancreatic Stomach Surgery National Cancer Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

BACKGROUND Laparoscopic assisted total gastrectomy(LaTG)is associated with reduced nutritional status,and the procedure is not easily carried out without extensive expertise.A small remnant stomach after near-total gastrectomy confers no significant nutritional benefits over total *** this study,we developed a modified laparoscopic subtotal gastrectomy procedure,termed laparoscopicassisted tailored subtotal gastrectomy(LaTSG).AIM To evaluate the feasibility and nutritional impact of LaTSG compared to those of LaTG in patients with advanced middle-third gastric cancer(GC).METHODS We retrospectively analyzed surgical and oncological outcomes and postoperative nutritional status in 92 consecutive patients with middle-third GC who underwent radical laparoscopic gastrectomy at Department of Pancreatic Stomach Surgery,National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences,and Peking Union Medical College between 2013 and *** these 92 patients,47 underwent LaTSG(LaTSG group),and the remaining underwent LaTG(LaTG group).RESULTS Operation time(210±49.8 min vs 208±50.0 min,P>0.05)and intraoperative blood loss(152.3±166.1 mL vs 188.9±167.8 mL,P>0.05)were similar between the *** incidence of postoperative morbidities was lower in the LaTSG group than in the LaTG group(4.2%vs 17.8%,Pbin levels,and red blood cell counts were significantly higher in the LaTSG group than in the LaTG group(P<0.05).No significant differences in Fe or C-reaction protein levels were found between the two *** examination demonstrated that reflux oesophagitis was more common in the LaTG group(0%vs 11.1%,P<0.05).Kaplan–Meier analysis showed a significant improvement in the overall survival(OS)and disease free survival(DFS)in the LaTSG *** analysis showed that LaTSG was an independent prognostic facto

关键词： Gastric cancer Laparoscopy assisted tailored gastrectomy Nutritional status Morbidity Reflux oesophagitis Resection margin

Extended culture of day 3 embryos improves live birth rate in in vitro fertilization-embryo transfer

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Chinese Medical Journal 2020年第14期133卷 1729-1731页

作者： Shao-Kang MoYuan-Kun Sang Xiao-peng Zhao Ling Wang Lu ma Di Zuo Fei Chang Li-Yuan Zhang Jun-Long Jia Shao-Kang Mo Yuan-Kun Sang bin-bin ma Fang Xu Key Laboratory of Fertility Preservation and maintenance Ministry of EducationSchool of Basic Medical SciencesNingxia Medical UniversityYinchuanNingxia 750004China Center for Reproductive Medicine The 940th Hospital of Joint Logistics Support Force of Chinese People’s Liberation ArmyLanzhouGansu 730050China Research Center for Regenerative Medicine Shanghai East HospitalSchool of Life Sciences and TechnologyTongji UniversityShanghai 200120China

To the Editor:Embryo development at the early cleavage stage is a complex and well-orchestrated biological *** in vitro fertilization-embryo transfer(IVF-ET),embryos are routinely stratified according to morphological criteria and transferred on the morning of day 3 after *** stage of embryonic development is mainly regulated by maternal factors because the embryonic genome has not yet been fully activated.[1]Day 3 is a key period for embryos to accomplish embryonic genome activation(EGA).Embryos with higher developmental potential initiate EGA for subsequent development and implantation,while non-viable embryos undergo arrest.

关键词： routine culture transfer

湘东北燕山期动力学背景约束：金井地区花岗质侵入岩年代学和地球化学特征

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矿物岩石地球化学通报 2024年第4期43卷 843-863页

作者：李银敏柏道远李彬姜文蒋启生彭云益湖南省地质调查所长沙 410016

湘东北地区燕山期岩浆活动频繁，侵入岩广泛发育，但其活动期次和构造背景尚存争议。本文对湘东北金井地区花岗质侵入岩开展了年代学和岩石地球化学研究，厘定了岩浆活动期次、探讨了岩浆活动的构造背景和动力学机制。结果显示侵入岩体... 详细信息

湘东北地区燕山期岩浆活动频繁，侵入岩广泛发育，但其活动期次和构造背景尚存争议。本文对湘东北金井地区花岗质侵入岩开展了年代学和岩石地球化学研究，厘定了岩浆活动期次、探讨了岩浆活动的构造背景和动力学机制。结果显示侵入岩体锆石SHRIMP U-Pb年龄为 165~160 ma和 155~150 ma，表明岩浆活动（晚侏罗世）可划分为两个期次。侵入岩具有富硅、富铝、富钾、高ASI的特点，总体属高钾钙碱性系列强过铝质花岗岩类，微量元素中Ba、Nb、Sr、P、Ti明显或强烈亏损，Nb相对Ta明显亏损，轻稀土富集且Eu具弱-中等亏损， I Sr值为0.713 83~0.729 19， ε Nd（ t）值为–10.98~–8.47， t DM2为1.64~1.83 Ga，显示源岩主要为中上地壳变质泥质岩和变质杂砂岩，少量为下地壳基性岩，总体属S型花岗岩。结合岩石地球化学特征和区域构造背景，本文提出 165~160 ma的岩浆活动主要与增厚的中上地壳发生减压熔融有关， 155~150 ma的岩浆活动与减压熔融及古太平洋俯冲板块崩塌导致软流圈上涌有关。

关键词：锆石U-Pb年龄 S型花岗岩晚侏罗世岩浆活动动力学背景金井地区湘东北

MOF-Derived ZnS Nanodots/Ti_(3)C_(2)T_(x) MXene Hybrids Boosting Superior Lithium Storage Performance

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Nano-Micro Letters 2021年第12期13卷 247-263页

作者： bin Cao Huan Liu Xin Zhang peng Zhang Qizhen Zhu Huiling Du lianli Wang Rupeng Zhang bin Xu State Key Laboratory of Organic-Inorganic Composites Beijing Key Laboratory of Electrochemical Process and Technology for MaterialsBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China College of materials Science and Engineering Xi’an University of Science and TechnologyXi’an 710054People’s Republic of China

ZnS has great potentials as an anode for lithium storage because of its high theoretical capacity and resource abundance;however,the large volume expansion accompanied with structural collapse and low conductivity of ZnS cause severe capacity fading and inferior rate capability during lithium storage. Herein,0D-2 D ZnS nanodots/Ti_(3)C_(2)T_x MXene hybrids are prepared by anchoring ZnS nanodots on Ti_(3)C_(2)T_(x) MXene nanosheets through coordination modulation between MXene and MOF precursor(ZIF-8) followed with sulfidation. The MXene substratecoupled with the ZnS nanodots can synergistically accommodate volume variation of ZnS over charge–discharge to realize stable cyclability. As revealed by XPS characterizations and DFT calculations,the strong interfacial interaction between ZnS nanodots and MXene nanosheets can boost fast electron/lithium-ion transfer to achieve excellent electrochemical activity and kinetics for lithium storage. Thereby,the as-prepared ZnS nanodots/MXene hybrid exhibits a high capacity of 726.8 mah g^(-1) at 30 ma g^(-1),superior cyclic stability(462.8 mah g^(-1) after 1000 cycles at 0.5 A g^(-1)),and excellent rate performance. The present results provide new insights into the understanding of the lithium storage mechanism of ZnS and the revealing of the e ects of interfacial interaction on lithium storage performance enhancement.

关键词： Ti_(3)C_(2)T_(x)MXene MOF Interfacial interaction Heterointerface ZnS Lithium-ion batteries

Factors associated with low adherence to head-of-bed elevation during mechanical ventilation in Chinese intensive care units

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Chinese Medical Journal 2013年第5期126卷 834-838页

作者： LIU Jing-tao SONG Hai-jing WANG Yu KANG Yan JIANG Li LIN Si-han DU bin ma peng-lin Department of Critical Care Medicine 309th Hospital of Chinese Peoples' Liberation Army Beijing 100091 China Department of Emergency Medicine 306th Hospital of ChinesePeoples' Liberation Army Beijing 100101 China Department of Critical Care Medicine West China Hospital WestChina School of Medicine Sichuan University Chengdu 610041Sichuan 610041 China Department of Critical Care Medicine Fuxing Hospital CapitalMedical University Beijing 100045 China Department of Epidemiology and Bio-Statistics School of PublicHealth Peking University Health Science Centre Beijing 100191China Medical Intensive Care Unit Peking Union Medical CollegeHospital Beijing 100730 China

Background Elevating the head of bed （HOB） 30°-45° has been widely supported as a means of ventilator associated pneumonia （VAP） prevention. However, it was poorly adhered in clinical practice. This observational study aimed to investigate the factors impeding this simple practice at the bedside. Methods This prospective study was conducted in 33 Chinese academic hospital intensive care units （ICUs）. HOB angle was measured four times daily at 5-7 hour intervals. The predefined HOB elevation goal was an angle ≥30°. Results The overall rate of achieving the HOB goal was 27.8% of the 8647 measurements in 314 patients during 2842 ventilation days. The HOB goal of ≥3 times/d was consistently achieved only in 15.9% of the cases. Almost 60% of patients had at least one 24 hours period during which the HOB goal was never documented. This low rate of protocol compliance was not associated with acute physiology and chronic health evaluation （APACHE） II score or dependence on vasopressors. In a survey, ＂nurse workload＂ was identified as the most important factor for non-compliance with the HOB goal. In addition, the rates of compliance were significantly different （P 〈0.001） between physicians self-reporting that they either did or did not know the Institutes of Healthcare Improvement （IHI） ventilator bundle. Conclusions Low adherence to a HOB angle of ≥30° was found in this nationwide survey. Nursing workload and lack of knowledge on VAP prevention were important barriers to changin.q this practice.

关键词： head of bed elevation clinical compliance ventilator associated pneumonia