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A fluorescence-enhanced inverse opal sensing film for multi-sources detection of formaldehyde

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Food Science and Human Wellness 2024年

作者： Xiaokang Lu Bo Han Deyilei Wei Mingzhu Chu haojie ma Ran Li Xueyan Hou Yuqi Zhang JiJiang Wang Key Laboratory of New Energy & New Functional materials Shaanxi Key Laboratory of Chemical Reaction Engineering College of Chemistry and Chemical Engineering Yan’an University

The SiO2inverse opal photonic crystals (PC) with a three-dimensional macroporous structure were fabricated by the sacrificial template method， followed by infiltration of a pyrene derivative， 1-(pyren-8-yl)but-3-en-1-amine (PEA)， to achieve a formaldehyde-sensitive and fluorescence-enhanced sensing film. Utilizing the specific Aza-Cope rearrangement reaction of allylamine of PEA and formaldehyde (FA) to generate a strong fluorescent product emitted at ～480 nm， we chose a PC whose blue band edge of stopband overlapped with the fluorescence emission wavelength. In virtue of the fluorescence enhancement property derived from slow photon effect of PC， FA was detected highly selectively and sensitively. The limit of detection (LoD) was calculated to be 1.38 nmol/L. Furthermore， the fast detection of FA (within 1 min) is realized due to the interconnected three-dimensional macroporous structure of the inverse opal PC and its high specific surface area. The prepared sensing film can be used for the detection of FA in air， aquatic products and living cells. The very close FA content in indoor air to the result from FA detector， the recovery rate of 101.5% for detecting FA in aquatic products and fast fluorescence imaging in 2 min for living cells demonstrate the reliability and accuracy of our method in practical applications.

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企业会计内部控制建设存在的问题及应对策略

市场周刊 2024年第8期37卷 44-47页

作者：马好杰克拉玛依融进实业发展有限公司新疆克拉玛依834014

现阶段,我国依旧有部分企业缺乏独立的会计部门,也没有拟定相应的会计内部控制制度,导致难以对企业内部的财务核算进行规范化管理和控制,其主要原因便在于一些企业缺乏对会计内部控制的足够重视,导致相关会计信息和数据不够完整准确,难... 详细信息

现阶段,我国依旧有部分企业缺乏独立的会计部门,也没有拟定相应的会计内部控制制度,导致难以对企业内部的财务核算进行规范化管理和控制,其主要原因便在于一些企业缺乏对会计内部控制的足够重视,导致相关会计信息和数据不够完整准确,难以充分发挥会计工作的实际作用。所以,文章对企业会计内部控制相关问题进行了分析,并给出了相应策略,希望能为企业会计内部控制工作的开展提供参考和借鉴。

关键词：会计内部控制执行力经济效益

智能二维光子晶体水凝胶精准检测Hg^(2+)

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化学学报 2024年第1期82卷 9-15页

作者：史雨晴储名珠韩波马豪杰李然侯雪艳张玉琦王记江延安大学化学与化工学院、陕西省化学反应工程重点实验室、延安市新能源新功能材料重点实验室陕西延安716000

结合二维光子晶体的德拜衍射效应和水凝胶的体积相转变特性,开发了一种智能二维光子晶体水凝胶,用于精准检测Hg^(2+).采用“三明治”法制备了聚苯乙烯二维光子晶体阵列嵌入的聚(丙烯酰胺-烯丙基硫脲)水凝胶.水凝胶链上功能基团的N、O、... 详细信息

结合二维光子晶体的德拜衍射效应和水凝胶的体积相转变特性,开发了一种智能二维光子晶体水凝胶,用于精准检测Hg^(2+).采用“三明治”法制备了聚苯乙烯二维光子晶体阵列嵌入的聚(丙烯酰胺-烯丙基硫脲)水凝胶.水凝胶链上功能基团的N、O、S等原子与Hg^(2+)选择性配位,缩短了水凝胶链之间的距离,增加了水凝胶的交联密度,使其收缩,导致二维光子晶体的聚苯乙烯微球间距缩小,德拜衍射环直径变大.通过监测二维光子晶体水凝胶响应前后的德拜衍射环直径,获知微球间距变化,实现了高灵敏、高选择性、快速、可逆检测Hg^(2+).线性检测范围为10~100nmol/L和25~200μmol/L,最低检测限3.32nmol/L.所制智能二维光子晶体水凝胶已成功应用于化妆品及水样中Hg^(2+)的检测.该方法测试简单,只需激光笔和刻度尺,无需精密的仪器设备,可实现便携式检测,为金属离子检测提供了新思路.

关键词：二维光子晶体德拜衍射效应智能水凝胶体积相转变汞离子

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某既有医院改造工程实践

广东建材 2024年第7期40卷 152-157页

作者：刘恺魏仓显翟高达马豪杰中铁建工集团有限公司

越来越多的城市中心区既有医院建筑面临改造的问题,但国内对城市中心区既有医院相关技术研究较少。番禺区何贤纪念医院由于修建年代较早,已不满足新时代需求,需要对其进行升级改造,以便缓解番禺区医疗资源短缺问题。本文依托番禺区何贤... 详细信息

越来越多的城市中心区既有医院建筑面临改造的问题,但国内对城市中心区既有医院相关技术研究较少。番禺区何贤纪念医院由于修建年代较早,已不满足新时代需求,需要对其进行升级改造,以便缓解番禺区医疗资源短缺问题。本文依托番禺区何贤纪念医院旧建筑改造案例,对改造项目进行系统研究。分析了城市中心区既有医院改造的重难点和解决对策,并对岩溶地层桩基纠偏关键技术和钢结构安装施工关键技术开展研究,形成系统技术体系,并在本工程中得到成功应用,以上研究和成果可供类似改造工程借鉴和应用。

关键词：城市中心区既有医院纠偏钢结构安装

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骨性Ⅱ类伴埋伏牙双期矫正病例1例

口腔医学 2024年第5期44卷 338-343页

作者：郭凯韩欣颖马浩杰刘丽娟杨芳红潍坊医学院口腔医学院山东潍坊261053 潍坊市人民医院口腔正畸科山东潍坊261041

骨性Ⅱ类的患者常表现为上颌前牙前突,下颌后缩,开唇露齿,前牙深覆牙合、深覆盖等症状,严重影响颜面美观。本文报道1例一期早期矫治配合二期固定矫治治疗骨性Ⅱ类伴埋伏牙的生长发育期男性患者病例。治疗后骨性Ⅱ类症状明显改善,包括下... 详细信息

骨性Ⅱ类的患者常表现为上颌前牙前突,下颌后缩,开唇露齿,前牙深覆牙合、深覆盖等症状,严重影响颜面美观。本文报道1例一期早期矫治配合二期固定矫治治疗骨性Ⅱ类伴埋伏牙的生长发育期男性患者病例。治疗后骨性Ⅱ类症状明显改善,包括下颌后缩的改善,开唇露齿问题得到解决,面部外观趋向于直面型,同时颞下颌关节未出现明显异常。该病例显示早期矫正对此类患者可以达到良好的治疗效果,可以避免或减少此类患者成年后正颌手术的可能性。

关键词：骨性Ⅱ类双期矫正埋伏牙 Twin-Block矫治器

Mechanism of Buyin Qianzheng Fang on preventing dopamine neuron from apoptosis by regulating intracellular Ca^(2+) in PD Mice

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解剖学杂志 2021年第S1期44卷 228-229页

作者： Zhao Haihong Feng Wandi ma haojie Cheng Cuicui Zhou Mengqi Gao Yushan Gai Cong Sun Hongsun Department of Anatomy Beijing University of Chinese MedicineBeijing 100029

The purpose of this study is to investigate the possible protective mechanism of Buyin Qianzheng Fang(BYQZF)on endoplasmic reticular and mitochondrial function through intracellular Ca^(2+) to protect dopamine neurons in Parkinson's disease mice model.C57BL/6 mice were randomly divided into normal group,model group,BYQZF group.The behavior of mice was observed by climbing and beam hang tests.

关键词： C57BL/6 dopamine protective

Electroacupuncture treatment attenuates stress-induced depressive-like behavior in rats through modulation of PNNs in the mPFC

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解剖学杂志 2021年第S1期44卷 232-233页

作者： Zhang Yuxcin Hu Die Gai Cong ma haojie Cheng Cuicui Zhang Jinkun Yang Luping Sun Hongmei College of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 102488

The perineuronal nets(PNNs)are a kind of extracellular matrix structure which mainly surround parvalbumin-positive(PV^(+))GABAergic interneurons.The aim of this study is to investigate the role of PNNs in the medial prefrontal cortex(mPFC)in the antidepressant effect of electroacupuncture treatment.Adult rats underwent chronic unpredictable mild stress(CUMS)for 28 days,and electroacupuncture treatment of Baihui and Yintang acupoints was administrated from day 8 to day 28.Then we detected the depressive-and anxiety like behavior of rats,the density of PNNs,the percentage of PV^(+)neurons that surround PNNs,the expression levels of PNNs constituting proteins in the mPFC.

关键词： PNNs rats treatment

Mechanism of mitochondrial protection by the Buyin Qianzheng formula in a Parkin overexpression cell model

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Journal of Traditional Chinese Medical Sciences 2022年第1期9卷 59-68页

作者： Cuicui Cheng Yushan Gao Cong Gai Wandi Feng haojie ma Jing Feng Zhenyu Guo Shujing Zhang Jie Wu Hongmei Sun School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing102488China Institute of Health Sciences National Engineering Research Center for Beijing Biochip TechnologyBeijing102206China Department of Physiology Mayo Clinic HospitalPhoenix85054USA

Objective:To identify the molecular mechanisms of the effects of the Buyin Qianzheng formula(BYQZF)on the mitochondrial dynamics in a Parkin overexpression Parkinson's disease(PD)cell model.Methods:First,a stable Parkin overexpression cell model was constructed using plasmid transfection.Then,we examined the protective effect of BYQZF on the mitochondrial dysfunction of the Parkin overexpression PD cell model induced by neurotoxin 1-methyl-4-phenylpyridinium ion(MPPþ).The mRNA expression level of Parkin was evaluated using real-time quantitative PCR.The cell survival rate was detected using the Cell Counting Kit-8 assay.We evaluated the cellular adenosine triphosphate(ATP)levels using luciferase assays.A laser scanning confocal microscope was used to observe the mitochondrial morphology,activity,and mitochondrial membrane potential(DJm).Western blot was conducted to evaluate the levels of the fusion proteins mitofusin1,mitofusin2,optic atrophy 1,dynaminrelated protein 1,and mitochondrial fission protein 1.Results:Parkin overexpression attenuated MPPþ-induced mitochondrial damage,increased mitochondrial activity and DJm.BYQZF increased the survival of MPPþ-induced cells that overexpressed Parkin and upregulated the mitochondrial form factor and activity.It also inhibited a decrease in the DJm and ATP levels.These findings suggested that BYQZF protected against MPPþ-induced mitochondrial dysfunction and enhanced the protective effect of Parkin overexpression.Furthermore,the formula upregulated the expression of the fusion proteins mitofusin1,mitofusin2,and optic atrophy 1(closely related to mitochondrial quality remodeling),and reduced the expression of the fission protein dynamicrelated protein 1,as well as mitochondrial fission protein 1.Conclusion:The mechanism by which BYQZF increased the mitochondrial protective effect of Parkin gene overexpression in MPPþ-induced cells may be related to improving mitochondrial function and regulating the balance of mitochondrial division and fusion proteins.

关键词： Parkinson's disease Parkin overexpression Mitochondria Buyin Qianzheng formula Neurotoxin 1-methyl-4-phenylpyridinium ion SH-SY5Y Mitofusin 2 Dynamic-related protein 1

浮式风机超高性能混凝土蜂窝基础及代表体元设计方法

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船舶工程 2023年第9期45卷 166-173,178页

作者：方辉马浩杰中国海洋大学工程学院山东青岛266100

提出一种超高性能混凝土蜂窝结构的浮式风机基础,并将其与具有相同外部几何特征的钢筋混凝土基础进行比较,发现文章所提新型浮式基础的比刚度和比强度显著增大。同时,发展代表体元法,将复杂蜂窝结构等效为均匀化连续体,给出工程设计中... 详细信息

提出一种超高性能混凝土蜂窝结构的浮式风机基础,并将其与具有相同外部几何特征的钢筋混凝土基础进行比较,发现文章所提新型浮式基础的比刚度和比强度显著增大。同时,发展代表体元法,将复杂蜂窝结构等效为均匀化连续体,给出工程设计中关键的弹性模量、塑性屈服点和屈服准则。该方法实现了复杂结构的参数化设计,在保证精度的同时,极大地提高了效率。浮式风机超高性能混凝土蜂窝基础结构与设计方法对于未来深水海上风电发展具有基础性的工程价值。

关键词：浮式风机基础混凝土蜂窝结构代表体元力学特性