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Synchronous and metachronous neoplasms in gastric cancer patients:A 23-year study

World Journal of Gastroenterology 2014年第23期20卷 7480-7487页

作者： magorzata lawniczak Alicja Gawin Halina Jaroszewicz-Heigelmann Wiesawa Rogoza-mateja Joanna Raszeja-Wyszomirska Andrzej Biaek Katarzyna Karpińska-Kaczmarczyk Teresa Starzyńska Department of Gastroenterology Pomeranian Medical University71-252 SzczecinPoland Liver Unit Pomeranian Medical University70-111 SzczecinPoland Department of Pathology Pomeranian Medical UniversityUnii Lubelskiej 171-252 SzczecinPoland

AIM: To determine the prevalence and characteristics of additional primary malignancies in gastric cancer (GC) patients.

关键词： Gastric cancer Multiple primary cancers Synchronous Metachronous Blood groups

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Nonalcoholic fatty liver disease and HFE gene mutations:A Polish study

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World Journal of Gastroenterology 2010年第20期16卷 2531-2536页

作者： Joanna Raszeja-Wyszomirska Grzegorz Kurzawski malgorzata lawniczak Joanna Miezynska-Kurtycz Jan Lubinski Liver Unit Pomeranian Medical University70-111 SzczecinPoland Department of Genetics and Pathology International Hereditary Cancer CentrePomeranian Medical University70-111 SzczecinPoland Department of Gastroenterology Pomeranian Medical University71-252 SzczecinPoland

AIM:To describe a Polish population with nonalcoholic fatty liver disease(NAFLD)with regard to HFE gene mutations,as well as analyzing demographic and clinical ***:Sixty-two consecutive patients with biopsy-proven NAFLD were included in the ***,clinical,and laboratory data were summarized in a database.C282Y and H63D mutations of the HFE gene were analyzed using polymerase chain reactionrestriction fragment lenght ***:The analyzed cohort consisted of 62 homo-geneic Caucasian participants,66.1%men and 33.9% women,with a median age of 48 *** median body mass index was 29.05 kg/m 2 .Hypercholesterolemia was observed in 74.2%of patients and hypertriglyceridemia in 32.2%;16.1%had type 2 diabetes mellitus(DMt2).On liver biopsy,22.6%of NAFLD patients were found to have severe *** were no differences between frequencies of HFE gene mutations in subgroups of NAFLD patients with less and more severe liver ***,older age,female gender and DMt2 were associated with more advanced fibrosis in this Polish cohort,as well as higher glucose level,serum iron and transaminase aspartate aminotransferase/alanine aminotransferase ***:HFE mutations conferred no additional hepatic fibrosis risk in NAFLD,but higher serum iron was a risk factor for severe liver damage in NAFLD,regardless of HFE mutations.

关键词： Nonalcoholic fatty liver disease HFE gene mutations Liver fibrosis

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Causes of Lake Area Changes in Poland

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Journal of Resources and Ecology 2011年第2期2卷 175-180页

作者： Adam CHOINSKI Agnieszka lawniczak mariusz PTAK Leszek SOBKOWIAK 亚当密茨凯维奇大学自然地理与环境规划研究所波兹南大学生命科学学院生态学与农业环境保护研究室

The northern part of Poland is occupied by numerous lakes formed during the last glaciation as a result of the Scandinavian ice sheet. Studies carried out in the lake district areas show progressive reduction of the surface area of the lakes, which leads to their eventual disappearance. The paper discusses the degree of the observed changes and points out main natural and anthropogenic factors influencing changes of lake area in Poland, including climate change, depth of lake basins, biomass growth, deforestation, hydrotechnical works, use of fertilizers and discharge of wastewater.

关键词： Northern Poland lake districts lake area changes natural factors anthropogenic factors

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