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Goblet cell carcinoid of the appendix:Six case reports

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World Journal of Clinical Cases 2024年第22期12卷 5217-5224页

作者： Toshiaki Toshima Ryo Inada Shinya Sakamoto Eri Takeda Takahiro Yoshioka Kento Kumon Naoki Mimura Nobuo Takata Motoyasu Tabuchi Kazuyuki Oishi Takuji Sato Kenta Sui Takehiro Okabayashi Kazuhide Ozaki Toshio Nakamura yuichi Shibuya Manabu Matsumoto Jun Iwata Department of Gastroenterological Surgery Kochi Health Sciences CenterKochi 781-8555Japan Department of Diagnostic Pathology Kochi Health Sciences CenterKochi 781-8555Japan

BACKGROUND Goblet cell carcinoid(GCC)of the appendix is a rare tumor characterized by neuroendocrine and adenocarcinoma *** preoperative diagnosis is very difficult,with most patients complaining mainly of abdominal *** tomography shows swelling of the appendix,so diagnosis is usually made incidentally after appendectomy based on a preoperative diagnosis of *** if a patient undergoes preoperative colonoscopy,accurate endoscopic diagnosis is very difficult because GCC shows a submucosal growth pattern with invasion of the appendiceal *** SUMMARY Between 2017 and 2022,6 patients with GCC were treated in our *** presenting complaint for 5 of these 6 patients was abdominal *** 5 patients underwent appendectomy,including 4 for a preoperative diagnosis of appendicitis and the other for diagnosis and treatment of an appendiceal *** sixth patient presented with vomiting and underwent ileocecal resection for GCC diagnosed from preoperative *** 2 patients with GCC underwent colonoscopy,no neoplastic changes were *** of the six patients showed lymph node metastasis on pathological *** of the last followup(median:15 mo),all cases remained alive without *** As preoperative diagnosis of GCC is difficult,this possibility must be considered during surgical treatments for presumptive appendicitis.

关键词： Goblet cell carcinoid Appendix Preoperative diagnosis Endoscopic diagnosis Surgical treatment Case report

Multiplication formulas for Kubert functions

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Frontiers of Mathematics in China 2014年第1期9卷 101-109页

作者： Hailong LI Jing MA yuichi URAMATSU Department of Mathematics Weinan Teachers' University Weinan 714000 China School of Mathematics Jilin University Changchun 130012 China Graduate School of Advanced Technology Kinki University Iizuka Fukuoka 820-8555 Japan

The aim of this paper is two folds. First, we shall prove a general reduction theorem to the Spannenintegral of products of （generalized） Kubert functions. Second, we apply the special case of Carlitz＇s theorem to the elaboration of earlier results on the mean values of the product of Dirichlet L-functions at integer arguments. Carlitz＇s theorem is a generalization of a classical result of Nielsen in 1923. Regarding the reduction theorem, we shall unify both the results of Carlitz （for sums） and Mordell （for integrals）, both of which are generalizations of preceding results by Frasnel, Landau, Mikolas, and Romanoff et al. These not only generalize earlier results but also cover some recent results. For example, Beck＇s lamma is the same as Carlitz＇s result, while some results of Maier may be deduced from those of Romanoff. To this end, we shall consider the Stiletjes integral which incorporates both sums and integrals. Now, we have an expansion of the sum of products of Bernoulli polynomials that we may apply it to elaborate on the results of afore-mentioned papers and can supplement them by related results.

关键词： Kubert function multiplication formula integral formula Bernoulli polynomial mean value

An Operator-based Nonlinear Vibration Control System Using a Flexible Arm with Shape Memory Alloy

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International Journal of Automation and computing 2020年第1期17卷 139-150页

作者： Hiroki Matsumori Ming-Cong Deng yuichi Noge Tokyo University of Agriculture and Technology

In the past,arms used in the fields of industry and robotics have been designed not to vibrate by increasing their mass and *** weight of arms has tended to be reduced to improve speed of operation,and decrease the cost of their *** the weight saving makes the arms lose their stiffness and therefore vibrate more easily,the vibration suppression control is needed for realizing the above ***,the use of various smart materials in actuators has *** particular,a shape memory alloy(SMA)is applied widely and has several advantages:light weight,large displacement by temperature change,and large force to mass ***,the SMA actuators possess hysteresis nonlinearity between their own temperature and displacement obtained by the *** hysteretic behavior of the SMA actuators affects their control *** previous research,an operator-based control system including a hysteresis compensator has been *** vibration of a flexible arm is dealt with as the controlled object;one end of the arm is clamped and the other end is *** effectiveness of the hysteresis compensator has been confirmed by simulations and ***,the feedback signal of the previous designed system has increased *** is difficult to use the system in the long-term because of the ***,the SMA actuator generates and radiates heat because electric current passing through the SMA actuator provides heat,and strain on the SMA actuator is *** long-time use of the SMA actuator,the environmental temperature around the SMA actuator varies through radiation of the *** exists a risk that the ambient temperature change dealt with as disturbance affects the temperature and strain of the SMA *** this research,a design method of the operator-based control system is proposed considering the long-term use of the *** the method,the hysteresis characteristics of the SMA actu

关键词： Operator theory nonlinear control stability right coprime factorization shape memory alloy hysteresis characteristics

Surface manipulation of a triple-conducting cathode for protonic ceramic fuel cells to enhance oxygen reduction activity and CO_(2) tolerance

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Journal of Energy Chemistry 2023年第12期87卷 450-459,I0012页

作者： Wenwen Zhang Hiroki Muroyama yuichi Mikami Toshiaki Matsui Koichi Eguchi Department of Energy and Hydrocarbon Chemistry Graduate School of EngineeringKyoto UniversityNishikyo-kuKyoto 615-8510Japan Technology Division Panasonic Holdings Corporation3-1-1 Yagumo-naka-machiMoriguchi CityOsaka 570-8501Japan

One of the main obstacles limiting the performance of protonic ceramic fuel cells(PCFCs) is the sluggish kinetics of the oxygen reduction reaction(ORR) at reduced ***,the surface manipulation of a triple-conducting cathode BaCe_(0.5)Pr_(0.3)Y_(0.2)O_(3-δ)(BCPY) by an efficient catalyst coating PrNi_(0.5)Co_(0.5)O_(3-δ)(PNC) to enhance the ORR activity and CO_(2) tolerance is *** developed PNC-coated BCPY cathode achieves the polarization resistance of 0.25 and 1.00 Ω cm^(2) at 600 and 500 ℃,respectively,approximately 1/5 of that for the pristine BCPY cathode(0.99 and 4.79 Ω cm^(2)),while maintaining an excellent CO_(2) *** single cell on a BaZr_(0.8)Yb_(0.2)O_(3-δ) electrolyte also exhibits a high peak power density of 0.79 W cm^(-2)at 700 ℃ and a stable operation for 200 h at 600 ℃.Such high ORR activity is mainly attributed to the synergistic effect of BCPY support and PNC ***,BCPY provides a tripleconducting path(mainly protons),and PNC nanoparticles facilitates surface oxygen exchange and steam adsorption/desorption processes due to the enriched surface oxygen *** study will provide a new design strategy for developing high-performance PCFCs cathode.

关键词： Triple-conducting cathode Surface manipulation Oxygen reduction reaction CO_(2)tolerance Protonic ceramicfuel cells

Up-grading of natural ilmenite ore by combining oxidation and acid leaching

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International Journal of Minerals,Metallurgy and Materials 2018年第7期25卷 729-736页

作者： Takehito Hiraki yuichi Maruyama Yuta Suzuki Satoshi Iloh Tetsuya Nagasaka Department of Metallurgy Graduate School of EngineeringTohoku UniversitySendai 980-8579Japan Toho Titanium Co. Ltd.Kanagawa 253-8510Japan Fanuc Co. Ltd.Oshino-muraYamanashi 401-0511Japan Before retirement:Graduate School of Environmental Studies Tohoku UniversitySendai 980-8579Japan

Rutile （TiO2） is heavily used in pigments mid colormlts, mid the most abundmlt source of rutile is ilmeinte. Upon oxidation of ilmeinte, mtile cml be formed wiffl modest energy consumption; furfflermore, after leaching, only a few byproducts are formed. Unfortunate- ly, one drawback is file necessarily long oxidative process of typically used mefflods. In fflis study, we show fflat a fluidized bed reactor cml be used to oxidize ilmeinte ore to rapidly form ruffle mid pseudobrookite （Fe2TiOs） phases. Ilmeinte was oxidized wiffl 5vo1% 02 in Ar at temperatures of 1173 K or 1223 K mid subsequently leached using a diluted H2SO4 solution to dissolve file pseudobrookite phase. The effects of acid concentration, temperature, mid cooling rate after oxidation were investigated. We show fflat file ilmeinte was rapidly oxidized to form rutile mid pseudobrookite phases at 1173 mid 1223 K in a 5vo1% O2/95vo1% Ar environment wifflin 40 min. The fmal maximum mtile yield was 84.2mo1% after leaching in （1 ＋ 1） H2SO4 solution at 393 K for 12 h.

关键词： ilmenite oxidation fluidized bed reactor acid leaching rutile pseudobrookite

Recent progress of chemotherapy and biomarkers for gastroesophageal cancer

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World Journal of Gastrointestinal Oncology 2019年第7期11卷 518-526页

作者： Osamu Maeda yuichi Ando Department of Clinical Oncology and Chemotherapy Nagoya University Hospital

Key cytotoxic drugs of chemotherapy for gastroesophageal cancer include fluoropyrimidine, platinum, taxanes and irinotecan. Concurrent chemoradiotherapy is one of the main treatment strategies, especially for esophageal cancer. As molecular target agents, the anti-HER2 antibody trastuzumab for HER2-positive gastric cancer and the anti-angiogenesis agent ramucirumab combined with paclitaxel have been proven to improve the survival of gastric cancer patients. Recently, anti-PD-1 antibodies have become available as second- or later-line chemotherapy. Microsatellite instability is also useful as a biomarker to select patients suitable for immunotherapy. Furthermore, genome-wide analysis has improved our understanding of the biological features and molecular mechanisms of gastroesophageal cancer and will provide optimized treatment selection.

关键词： Gastroesophageal cancer Chemotherapy Biomarker HER2

Classification of solar sail attitude dynamics with and without angular momentum

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Astrodynamics 2019年第3期3卷 207-216页

作者： yuichi Tsuda Go Ono Yuya Mimasu Institute of Space and Astronautical Science Japan Aerospace Exploration AgencySagamihara252-5210Japan Japan Aerospace Exploration Agency Sagamihara252-5210Japan

This paper describes attitude dynamics properties of spinning,momentum-biased and zero-momentum solar sail *** model called“Generalized Sail Dynamics Model”(GSDM)is introduced,which can deal with general and practical sail configurations,such as arbitrary optical property distribution,shape and surface *** stability criteria and other key dynamical characteristics are derived and compared by compact analytical equations induced from the *** newly derived zero-momentum sail dynamics is compared with that of spinning and momentum-biased *** is shown that the spinning and momentum sails have an advantage in terms of dynamical stability whereas zero-momentum sails are only statically *** this special property,angular momentum-stabilized sails can realize a sun-pointing stable attitude with almost zero-fuel,which are discussed with actual space flight experience of the JAXA’s two interplanetary missions,IKAROS and Hayabusa2.

关键词： solar sail attitude dynamics stability solar system exploration

Simultaneous estimation of spacecraft position and asteroid diameter during final approach of Hayabusa2 to Ryugu

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Astrodynamics 2020年第2期4卷 163-175页

作者： Yuki Takao Yuya Mimasu yuichi Tsuda Institute of Space and Astronautical Science Japan Aerospace Exploration AgencySagamihara252-5210Japan

This paper presents the optical navigation results of the asteroid explorer Hayabusa2 during the final rendezvous approach phase with the asteroid *** orbit determination of Hayabusa2 during the cruising phase uses a triangulation-based method that estimates the probe and asteroid orbits using the directions from which they are ***,the asteroid size is available as optical information just prior to *** size information allows us to estimate the relative distance between the probe and the asteroid with high accuracy,that is strongly related to the success or failure of the *** this study,the relative distance and asteroid size in real space are simultaneously estimated in real time by focusing on the rate of change of the asteroid size observed in sequential *** real-time estimation results coincided with those of precise analyses performed after arrival.

关键词： asteroids small bodies optical navigation size estimation orbit determination real time

A preliminary study on the effects of line and selective thinning on bird communities in Hokkaido, northern Japan

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Journal of Forestry Research 2013年第3期24卷 553-559页

作者： Yuya Toyoshima yuichi Yamaura Yuki Yabuhara Futoshi Nakamura Division of Environmental Resources Graduate School of Agriculture Hokkaido UniversityNishi 9 Kita 9 Kitaku Sapporo Hokkaido 0608589 Japan

In Japan, selective thinning is a common thinning method, though line thinning receives much attention because of its economic merits. In this study, we examined effects of the two thinning methods on bird communities in Todo fir （Abies sachalinensis） plantations in Hok- kaido, Japan. We surveyed bird species in forests under four different management types - unthinned, selectively thinned, line-thinned planta- tion, and naturally regenerated forest （here after referred to as natural forest） stands - using a line-transect method. We also investigated vege- tation structure （canopy tree and understory） of these stands. Bird species richness did not differ between natural forests and plantations, while bird total abundance was greater in plantations than in natural forests. Bird species richness and total abundance were comparable among the three management types for plantations. Abundances of 10 bird species were different among the four management types, and five species were more abundant in line-thinned plantations. However, two species were more abundant in selectively thinned stands than in line-thinned stands, and they frequently appeared in natural forests. There were no distinct differ- ences in vegetation structure among the management types for planta- tions. Our results suggest that line thinning could be beneficial for some bird species in plantations.

关键词： line thinning selective thinning Todo fir (Abies sachalinen-sis) plantation improved indicator species analysis bird community