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Simulation of Suspended Sediment in the Yellow and East China Seas

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China Ocean Engineering 2005年第2期19卷 235-250页

作者： CHOI Byung-Ho mun jong-yoon KO Jin-Seok YUK Jin-Hee Department of Civil and Environmental Engineering Sungkyunkwan University Suwon 440-746 KoreaKorea Ocean Science and Engineering Corporation 175-9 Huam-dong Yongsan-gu Seoul 140-901 KoreaHyein Engineering and Construction Co. Ltd. 150-057 761 Shingil 7 dong Yungdungpogu Seoul KoreaDepartment of Civil and Environmental Engineering Sungkyunkwan University Suwon 440-746 Korea

Described is an initial attempt to simulate the suspended sediment dynamics relating to tidal and wave forcing during summertime in June 1980 and August 1981 for the Yellow and East China Seas continental shelf. The cohesive/non-cohesive sediment resuspension and movement generated by the interaction between current and wave are modeled by use of ECOMSED and WAM Cycle 4. Model results are compared with observations in US-China Marine Sedimentation Dynamics Program performed for 1980-81 at off the Changjiang estuary. The main features of simulations show that suspended sediment concentrations during the summer decreased markedly offshore as observed during the simulation periods. As for some discrepancies for the mouth of the estuary with high river discharges, i.e., the Changjiang River, the model did not properly reproduce the over-mixing situation in the summer; thus distinct vertical concentration variation in this local region is not agreeable with observation. However, general dispersal patterns of suspended sediment movement seem to be agreeably reproduced for the nearshore shallow region. Some of the procedures of simulation and results are presented and discussed.

关键词： Yellow Sea East China Sea sediment transport model time slice experiment sediment concentration

Modification strategies improving the electrochemical and structural stability of high-Ni cathode materials

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Journal of Energy Chemistry 2024年第9期96卷 185-205页

作者： yoon Bo Sim Hami Lee Junyoung mun Ki Jae Kim Department of Energy Science Sungkyunkwan UniversitySuwon 16419Republic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwon 16419Republic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwon 16419Republic of Korea

With the increasing spotlight in electric vehicles,there is a growing demand for high-energy-density batteries to enhance driving ***,several studies have been conducted on high-energy-density LiNi_(x)Co_(y)Mn_(z)O_(2)***,there is a limit to permanent performance deterioration because of side reactions caused by moisture in the atmosphere and continuous microcracks during cycling as the Ni content to express high energy increases and the content of Mn and Co that maintain structural and electrochemical stabilization *** direct modification of the surface and bulk regions aims to enhance the capacity and long-term performance of high-Ni cathode ***,an efficient modification requires a study based on a thorough understanding of the degradation mechanisms in the surface and bulk *** this review,a comprehensive analysis of various modifications,including doping,coating,concentration gradient,and single crystals,is conducted to solve degradation issues along with an analysis of the overall degradation mechanism occurring in high-Ni cathode *** also summarizes recent research developments related to the following modifications,aims to provide notable points and directions for post-studies,and provides valuable references for the commercialization of stable high-energy-density cathode materials.

关键词： High energy density High-Ni cathode materials Degradation Structural stability Lithium-ion battery

Reconstruction of Rabbit Corneal Layer Composed of Corneal Fibroblasts and Corneal Epithelium on the Lyophilized Amniotic Membrane

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Chemical Research in Chinese Universities 2006年第2期22卷 150-156页

作者： AHN Jae-il JANG In-keun yoon mun-young SEO Young-kwon yoon Hee-hun KIN Jae-chan SONG Kye-yong YANG Eun-kyung PARK Jung-keug Department of Chemical and Biochemical Engineering Dongguk University Seoul Korea Department of Ophthalmology Chung-Ang University Hospital Seoul Korea Department of Pathology College of Medicine Chung-Ang University Seoul Korea R & D Center Bioland Ltd. Chun-An Korea

Many researchers have employed the cryopreserved amniotic membrane（CAM） and corneal epithelial cells in the treatment of a severely damaged burned cornea, with corneal epithelial cells cultured on an amniotic membrane （AM）. The lyophilized amniotic membrane（LAM） has a higher graft take and a longer shelf life; it is easier to store and safer because of gamma irradiation. Two Teflon rings（ Ahn＇s supporter） were made for culturing the cells on the LAM, and were then used to support the LAM. To reconstruct a corneal layer composed of corneal fibroblasts and epithelium, the corneal fibroblasts were first cultivated on the stromal side of LAM for five days, foUowed by epithelial cells culture on the epithelial side, by using the air-liquid interface culture. The reconstructed corneal layer composed of corneal fibroblasts and corneal epithelial cells has a much healthier basal layer of corneal epithelium than the reconstructed corneal epithelium, which was got by using only corneal epithelial cells, and resembles the epithelium of normal corneas, without the horny layer. Thus, the reconstruction of the corneal layer by using a LAM is considered to be a good in vitro model, not only for its application in toxicological test kits, but also for transplantation in patients with a severely damaged cornea.

关键词： Lyophilized amniotic membrane Corneal layer Corneal fibroblast Corneal epithelium

Inhibition of CD82 improves colitis by increasing NLRP3 deubiquitination by BRCC3

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Cellular & Molecular Immunology 2023年第2期20卷 189-200页

作者： Jae-Sung Kim Hyo Keun Kim Joongho Lee Sein Jang Euni Cho Seok-Jun mun Seokhyun yoon Chul-Su Yang Department of Bionano Technology Hanyang UniversitySeoul04673Korea Institute of Natural Science&Technology Hanyang UniversityAnsan15588Korea Department of Molecular and Life Science Hanyang UniversityAnsan15588Korea Center for Bionano Intelligence Education and Research Ansan15588Korea Department of Computer Science College of SW ConvergenceDankook UniversityYongin16890Korea Department of Electronics&Electrical Engineering College of EngineeringDankook UniversityYongin16890Korea

CD82 is a transmembrane protein that is involved in cancer suppression and activates immune cells;however, information on the NLRP3 inflammasome is limited. Herein, we show that although CD82 suppressed the activation of the NLRP3 inflammasome in vivo and in vitro, CD82 deficiency decreased the severity of colitis in mice. Furthermore, two binding partners of CD82, NLRP3 and BRCC3, were identified. CD82 binding to these partners increased the degradation of NLRP3 by blocking BRCC3-dependent K63-specific deubiquitination. Previous studies have shown that CD82-specific bacteria in the colon microbiota called Bacteroides vulgatus (B. vulgatus) regulated the expression of CD82 and promoted the activation of the NLRP3 inflammasome. Accordingly, we observed that B. vulgatus administration increased mouse survival by mediating CD82 expression and activating NLRP3 in mice with colitis. Overall, this study showed that CD82 suppression reduced the pathogenesis of colitis by elevating the activation of the NLRP3 inflammasome through BRCC3-dependent K63 deubiquitination. Based on our findings, we propose that B. vulgatus is a novel therapeutic candidate for colitis.

关键词： CD82 NLRP3 BRCC3 Colitis Inflammation

Suppression of Oxidative Stress of Modified Gongjin-Dan (WSY^1075) in Detrusor Underactivity Rat Model Bladder Outlet Induced by Obstruction

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Chinese Journal of Integrative Medicine 2018年第9期24卷 670-675页

作者： Jin-Woo Jung Seung Hwan Jeon Woong Jin Bae Su Jin Kim mun Su Chung Byung II yoon Sae Woong Choi U Syn Ha Sung Yeoun Hwang Sae Woong Kim Department of Urology International St. Mary's Hospital Catholic Kwandong University College of Medicine Incheon Republic of Korea Institute for Bio-Medical Convergence College of Medicine Catholic Kwandong University Gangneungsi Gangwon-do Republic of Korea Department of Urology College of Medicine The Catholic University of Korea Seoul Republic of Korea Catholic Integrative Medicine Research Institute College of Medicine The Catholic University of Korea Seoul Republic of Korea Korea Bio Medical Science Institute Seoul Republic of Korea

Objective： To investigate the anti-oxidative stress and preventive effect of modified Gongjin-dan （WSY-1075） in a detrusor underactivity rat model. Methods： Rats were randomly allocated to three groups： sham- operated （control）, bladder outlet obstruction-induced detrusor underactivity （BOO-DU）, and BOO-DU with WSY-1075 （WSY） groups. WSY-1075 was orally administrated to rats 200 mg daily for 2 weeks pdor to the operation and 4 weeks after the operation. Bladder outlet obstruction was surgically induced in rats by ligation around the urethra avoiding total obstruction. Cystometrography was conducted on rats in each group for examination of bladders. Results： Compared with the control group, bladder outlet obstruction led to a significant increase in oxidative stress with consequent changes to molecular composition, and decrease in maximal detrusor pressure （P〈0.05）. WSY-1075 treatment significantly suppressed oxidative stress and prevented degenerative and dysfunctional changes in bladder, as compared with BOO-DU group （P〈0.05）. Conclusion： WSY-1075 had beneficial effect on prevention of BOO-DU.

关键词： detrusor underactivity anti-oxidant herbal

Ultra-thin light-weight laser-induced-graphene (LIG) diffractive optics

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Light(Science & Applications) 2023年第7期12卷 1268-1300页

作者： Younggeun Lee mun Ji Low Dongwook Yang Han Ku Nam Truong-Son Dinh Le Seung Eon Lee Hyogeun Han Seunghwan Kim Quang Huy Vu Hongki Yoo Hyosang yoon Joohyung Lee Suchand Sandeep Keunwoo Lee Seung-Woo Kim Young-Jin Kim Department of Mechanical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daehak-roYuseong-guDaejeon 34141Republic of Korea School of Mechanical and Aerospace Engineering Nanyang Technological University(NTU)50 Nanyang Avenue639798 SingaporeSingapore Panasonic Factory Solutions Asia Pacific(PFSAP) 285 Jalan Ahmad Ibrahim639931 SingaporeSingapore Department of Aerospace Engineering Korea Advanced Institute of Science and Technology(KAlST)Daehak-roYuseong-guDaejeon 34141Republic of Korea Department of Mechanical System Design Engineering Seoul National University of Science and Technology(Seuoltech)232 Gongneung-roNowon-guSeoul 01811Republic of Korea LASER N GRAPN INC 193 Munj-roYuseong-guDaejeon 34051Republicof Korea

The realization of hybrid optics could be one of the best ways to fulfll the technological requirements of compact,light-weight,and multi-functional optical systems for modern *** diffractive lens(PDL)such as diffractive lenses,photonsieves,and metasurfaces can be patterned on ultra-thin flexible and stretchable substrates and be conformally attached on top of arbitrarily shaped *** this review,we introduce recent research works addressed to the design and manufacturing of ultra-thin graphene optics,which will open new markets in compact and light-weight optics for next-generation endoscopic brain imaging,space internet,real-time surface proflometry,and multi-functional mobile *** provide higher design flexibility,lower process complexity,and chemical-free process with reasonable investment cost,direct laser writing(DLW)of laser-induced-graphene(LIG)is actively being applied to the patterning of *** realizing the best optical performances in DLW,photon-material interactions have been studied in detail with respect to different laser parameters;the resulting optical characteristics have been evaluated in terms of amplitude and phase.A series of exemplary laser-written 1D and 2D PDL structures have been actively demonstrated with different base materials,and then,the cases are being expanded to plasmonic and holographic *** combination of these ultra-thin and light-weight PDL with conventional bulk refractive or reflective optical elements could bring together the advantages of each optical *** integrating these suggestions,we suggest a way to realize the hybrid PDL to be used in the future micro-electronics surface inspection,biomedical,outer space,and extended reality(XR)industries.

关键词： optics weight holographic

Photonic control of ligand nanospacing in self-assembly regulates stem cell fate

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Bioactive Materials 2024年第4期34卷 164-180页

作者： Sungkyu Lee Jounghyun Yoo Gunhyu Bae Ramar Thangam Jeongyun Heo Jung Yeon Park Honghwan Choi Chowon Kim Jusung An Jungryun Kim Kwang Rok mun Seungyong Shin Kunyu Zhang Pengchao Zhao Yuri Kim Nayeon Kang Seong-Beom Han Dahee Kim Jiwon yoon Misun Kang Jihwan Kim Letao Yang Solmaz Karamikamkar Jinjoo Kim Yangzhi Zhu Alireza Hassani Najafabadi Guosheng Song Dong-Hwee Kim Ki-Bum Lee Soong Ju Oh Hyun-Do Jung Hyun-Cheol Song Woo Young Jang Liming Bian Zhiqin Chu Juyoung yoon jong Seung Kim Yu Shrike Zhang Yongju Kim Ho Seong Jang Sehoon Kim Heemin Kang Department of Materials Science and Engineering Korea UniversitySeoul02841Republic of Korea Chemical and Biological Integrative Research Center Korea Institute of Science and TechnologySeoul02792Republic of Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoul02841Republic of Korea Department of Chemistry Korea UniversitySeoul02841Republic of Korea Materials Architecturing Research Center Korea Institute of Science and TechnologySeoul02792Republic of Korea School of Biomedical Sciences and Engineering Guangzhou International CampusSouth China University of TechnologyGuangzhou511442China Department of Chemistry and Chemical Biology Rutgers UniversityPiscatawayNJ08854USA Terasaki Institute for Biomedical Innovation Los AngelesCA90064USA State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha410082China Department of Biomedical-Chemical Engineering The Catholic University of KoreaGyeonggi-do14662Republic of Korea Electronic Materials Research Center Korea Institute of Science and TechnologySeoul02792Republic of Korea KIST-SKKU Carbon-Neutral Research Center Sungkyunkwan University(SKKU)Suwon16419Republic of Korea Department of Orthopedic Surgery Korea University Anam HospitalSeoul02841Republic of Korea Department of Electrical and Electronic Engineering and Joint Appointment with School of Biomedical Sciences The University of Hong KongHong Kong518057China Department of Chemistry and Nanoscience Ewha Womans UniversitySeoul03760Republic of Korea Division of Engineering in Medicine Department of MedicineBrigham and Women’s Hospital Harvard Medical SchoolCambridgeMA02139USA Division of Nano&Information Technology KIST SchoolKorea University of Science and Technology(UST)Seoul02792Republic of Korea College of Medicine Korea UniversitySeoul02841Republic of Korea Division of Materials Science and Engineering Hanyang UniversitySeoul04763Republic of Korea

Extracellular matrix(ECM)undergoes dynamic inflation that dynamically changes ligand nanospacing but has not been *** we utilize ECM-mimicking photocontrolled supramolecular ligand-tunable Azo^(+)self-assembly composed of azobenzene derivatives(Azo^(+))stacked via cation-πinteractions and stabilized with RGD ligand-bearing poly(acrylic acid).Near-infrared-upconverted-ultraviolet light induces cis-Azo^(+)-mediated inflation that suppresses cation-πinteractions,thereby inflating liganded *** inflation increases nanospacing of“closely nanospaced”ligands from 1.8 nm to 2.6 nm and the surface area of liganded selfassembly that facilitate stem cell adhesion,mechanosensing,and differentiation both in vitro and in vivo,including the release of loaded molecules by destabilizing water bridges and hydrogen bonds between the Azo^(+)molecules and loaded ***,visible light induces trans-Azo^(+)formation that facilitates cation-πinteractions,thereby deflating self-assembly with“closely nanospaced”ligands that inhibits stem cell adhesion,mechanosensing,and *** stark contrast,when ligand nanospacing increases from 8.7 nm to 12.2 nm via the inflation of self-assembly,the surface area of“distantly nanospaced”ligands increases,thereby suppressing stem cell adhesion,mechanosensing,and ***-term in vivo stability of self-assembly via real-time tracking and upconversion are *** tuning of ligand nanospacing can unravel dynamic ligand-cell interactions for stem cell-regulated tissue regeneration.

关键词： Dynamic self-assembly Ligand nanospacing In vivo tracking Stem cell adhesion Stem cell fate

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以水性胶粘剂为内层的环保型黄土涂装材料

以水性胶粘剂为内层的环保型黄土涂装材料

聚醚醚酮制作可摘义齿人工牙耐磨性及硬度的研究

'2007北京国际粘接技术研讨会暨第二届亚洲粘接技术研讨会

作者： Jae-yoon An Ki-Wook Kim Hyun-Joong Kim mun-Jae Park Laboratory of Adhesion and Bio-Composites Program in Environmental Materials ScienceSeoul National University Korea Forest Research Institute dongdaemun-guSeoul 130-712S.Korea

现今人们约有90%的时间是在室内度过的。自1960年工业快速发展以来,建筑材料也从原来的自然材料发展到化学材料,并且建筑物的密封性也因节能的需求而得到了提高。这些都导致了不良建筑综合症(SBS)的出现。于是人们希望他们房子中的建筑...

现今人们约有90%的时间是在室内度过的。自1960年工业快速发展以来,建筑材料也从原来的自然材料发展到化学材料,并且建筑物的密封性也因节能的需求而得到了提高。这些都导致了不良建筑综合症(SBS)的出现。于是人们希望他们房子中的建筑材料是环保型材料。我们设计了一种黄土涂装材料,它是由黄土、水、树脂、硬化剂和填料组成的。本研究目的是制备一种环保型黄土涂装材料,并对其在墙面的使用性能进行评价。另外,可以对墙面的机械性能、挥发性有机化合物、甲醛的释放及红外辐射进行评估。

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口腔颌面修复学杂志 2018年第4期19卷 236-240页

作者：金智文韩建民刘云松尹祯敏孙玉春叶红强周永胜北京大学口腔医学院·口腔医院修复科国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室北京100081 北京大学口腔医学院·口腔医院口腔材料研究室国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室北京100081 北京大学口腔医学院·口腔医院口腔医学数字化中心卫生计生委口腔医学计算机应用工程技术研究中心国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室北京100081

目的:比较聚醚醚酮制作的可摘义齿人工牙与两种临床常用的可摘义齿树脂人工牙的耐磨性及硬度。方法:用聚醚醚酮制作可摘义齿人工牙(A组),以普通合成树脂牙(拜耳牙,B组)和复合树脂牙(Endura塑钢牙,C组)为对照进行二体磨耗实验和硬度测试... 详细信息

目的:比较聚醚醚酮制作的可摘义齿人工牙与两种临床常用的可摘义齿树脂人工牙的耐磨性及硬度。方法:用聚醚醚酮制作可摘义齿人工牙(A组),以普通合成树脂牙(拜耳牙,B组)和复合树脂牙(Endura塑钢牙,C组)为对照进行二体磨耗实验和硬度测试。用TCML-II咀嚼模拟疲劳试验机进行磨耗实验,以滑石瓷为对磨物,加载力50N,循环加载30万次,并经5℃/55℃冷热水循环。用口内扫描仪扫描磨耗前后的人工牙形态,计算磨耗前后的体积变化,并用扫描电镜观察其磨耗表面。用显微硬度仪测量人工牙的维氏硬度。结果:三种树脂牙磨耗量分别为A组0.90±0.33 mm^3、B组2.42±0.99 mm^3、C组4.23±1.33 mm^3,三者之间有显著性差异(P<0.05)。三种树脂牙的硬度分别为A组29.16±2.58 Hv1/15、B组26.89±1.96 Hv1/15、C组35.24±1.90H v1/15,三者之间显著性差异(P<0.05)。结论:相比于普通合成树脂牙和复合树脂牙,PEEK树脂牙具有适中的硬度和良好的耐磨性。

关键词：聚醚醚酮人工牙耐磨性硬度