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Phytoconstituents Profiling of Indigenous Herbal Drugs and Its in vitro Microbial,in Silico Biological Examination against Severe Acute Respiratory Syndrome Coronavirus 2

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World Journal of Traditional Chinese Medicine 2024年第1期10卷 121-136页

作者： T.H.Mohamed Ahadu Shareef MMohamed Divan Masood Irfan Navabshan msaiyad musthafa Department of Chemistry The New College(Autonomous)Affiliated to the University of MadrasChennaiTamil NaduIndia School of Computer Applications B.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil NaduIndia Crescent School of Pharmacy B.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil NaduIndia Department of Zoology The New College(Autonomous)Affiliated to the University of MadrasChennaiTamil NaduIndia

Background:Habb-E-Shifa,Hamdard Sualin,and Hamdard Joshanda traditional herbal medicines may promote host resistance against infection by bacteria,viruses,and fungi which are easily accessible at inexpensive with no *** herbal medicines are used to cure sore throat,cough,fever,lung cancer,and asthma patients in developing South Asian *** traditional herbal medicines acted a crucial role in the prevention and control of coronavirus disease 2019(COVID-19).Aims and Objectives:This research article aimed at conducting phytochemistry,antimicrobial activity,COVID-19 docking and some spectroscopic(Infrared,Ultraviolet,13C-Nuclear Magnetic Resonance(13C-NMR),1H-NMR,and Mass Spectra)characterizations of the polyherbal drugs were carried ***,In-vitro and In-silico analyses were performed to measure activity against *** Performance-Liquid Chromatography(HPLC),Gas Chromatography-Mass Spectrometry(GC-MS),antimicrobial,and docking studies were carried *** preliminary phytochemical assay and bioactive compounds were screened using HPLC and *** study is an attempt to assess the promising effects of selected polyherbal indigenous drugs such as Habb-E-Shifa,Hamdard Sualin,and Hamdard Joshanda phytoconstituents against the severe acute respiratory syndrome coronavirus-2(SARS-Co V-2).Materials and Methods:The extract of the selected polyherbal formulations showed high-to-moderate preventive effects on the growth inhibition in the pathogenic bacterium,namely Streptococcus oralis,Staphylococcus aureus,Propionibacterium acnes,Pseudomonas aeruginosa,Escherichia coli,and Proteus vulgaris,and three fungal Candida albicans,Aspergillus fumigatus,and Aspergillus *** docking study evaluates the pharmacological activity of bioactive chemical compounds with SARS-Co V-2 NSP5(PDB ID:7nxh)and SARS-Co V-2 Omicron spike protein with human angiotensin-converting enzyme 2(ACE-2)(PDB ID:7wk6).Results:In this study,for the first time,we at

关键词： Antimicrobial herbal drug Omicron and coronavirus disease 2019 phytochemicals spectroscopic

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Tight Focusing Properties of Phase Modulated Radially Polarized Laguerre Bessel Gaussian Beam

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Chinese Physics Letters 2017年第5期34卷 56-59页

作者： K.Prabakaran P.Sangeetha V.Karthik K.B.Rajesh A.M.musthafa Department of Physics Mahendra Arts and Science College (Autonomous) Namakkal Tamilnadu India Department of Physics Chikkanna Government Arts College Tiruppur Tamilnadu India Department of General Studies (Physics Group) Jubail University College (Male Branch) Royal Commission of Jubail Kingdom of Saudi Arabia

We propose a new approach for generating a multiple focal spot segment of subwavelength size, by tight focusing of a phase modulated radially polarized Laguerre Bessel Gaussian beam. The focusing properties are investigated theoretically by .vector diffraction theory. We observe that the focal segment with multiple focal structures is separated with different axial distances and a super long dark channel can be generated by properly tuning the phase of the incident radially polarized Laguerre Bessel Gaussian beam. We presume that such multiple focal patterns and high intense beam may find applications in atom optics, optical manipulations and multiple optical trapping.

关键词： Tight Focusing Properties of Phase Modulated Radially Polarized Laguerre Bessel Gaussian Beam

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Creation of Super Long Transversely Polarized Optical Needle Using Azimuthally Polarized Multi Gaussian Beam

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Chinese Physics Letters 2016年第6期33卷 29-32页

作者： C.M.Sundaram K.Prabakaran P.M.Anbarasan K.B.Rajesh A.M.musthafa Department of Physics Periyar University Department of Physics Mahendra Arts and Science College(Autonomous) Department of Physics Chikkanna Government Arts College Department of General Studies(Physics Group) Jubail University College(Male Branch)Royal Commission of Jubail

The intensity distribution in the focal region of a high-NA lens for the incident azimuthally polarized multi Gaussian beam transmitted through a multi belt spiral phase hologram is studied on the basis of the vector diffraction theory. Here we report a new method used to generate a needle of transversely polarized light beam with sub diffraction beam size of 0.366A that propagates without divergence over a long distance of about 22A in free space. We also expect that such a light needle of transversely polarized beam may find its applications in utilizing optical materials or instruments responsive to the transversal field only.

关键词： of on it for Creation of Super Long Transversely Polarized Optical Needle Using Azimuthally Polarized Multi Gaussian Beam in that is

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IoT-Enabled Plant Monitoring System with Power Optimization and Secure Authentication

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Computers, Materials & Continua 2024年第11期81卷 3165-3187页

作者： Samsul Huda Yasuyuki Nogami Maya Rahayu Takuma Akada MdBiplob Hossain Muhammad Bisri musthafa Yang Jie Le Hoang Anh Green Innovation Center Okayama UniversityOkayama700-8530Japan Graduate School of Environmental LifeNatural Science and TechnologyOkayama UniversityOkayama700-8530Japan

Global food security is a pressing issue that affects the stability and well-being of communities *** existing Internet of Things(IoT)enabled plant monitoring systems have made significant strides in agricultural monitoring,they often face limitations such as high power consumption,restricted mobility,complex deployment requirements,and inadequate security measures for data *** paper introduces an enhanced IoT application for agricultural monitoring systems that address these critical *** system strategically combines power efficiency,portability,and secure access capabilities,assisting farmers in monitoring and tracking crop environmental *** proposed system includes a remote camera that captures images of surrounding plants and a sensor module that regularly monitors various environmental factors,including temperature,humidity,and soil *** implement power management strategies to minimize energy consumption compared to existing *** conventional systems,our implementation utilizes the Amazon Web Services(AWS)cloud platform for reliable data storage and processing while incorporating comprehensive security measures,including Two-Factor Authentication(2FA)and JSON Web Tokens(JWT),features often overlooked in current agricultural IoT *** can access this secure monitoring system via a developed Android application,providing convenient mobile access to the gathered plant *** validate our system’s advantages by implementing it with two potted garlic plants on Okayama University’s *** evaluation demonstrates high sensor reliabil-ity,with strong correlations between sensor readings and reference data,achieving determination coefficients(R2)of 0.979 for temperature and 0.750 for humidity *** implemented power management strategies extend battery life to 10 days on a single charge,significantly outperforming existing systems that typically require daily ***

关键词： Plant monitoring agriculture food security environmental monitoring IoT power management AWS secure access JWT

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Q-switched giant pulsed erbium-doped all-fiber laser with V_(2)ZnC MAX phase saturable absorber

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Optoelectronics Letters 2024年第6期20卷 321-329页

作者： Kawther M musthafa Azura Hamzah Ooi Wei Ling Ahmad Haziq Aiman Rosol Norliza Mohamed Sulaiman Wadi Harun Malaysia-Japan International Institute of Technology Universiti Teknologi MalaysiaKuala Lumpur 54100Malaysia Razak Faculty of Technology and Informatics Universiti Teknologi MalaysiaKuala Lumpur 54100Malaysia Department of Electrical Engineering University of MalayaKuala Lumpur 50603Malaysia1

MXenes,drawn from MAX phases,are special two-dimensional substances with numerous advantages in nonlinear optics,specifically in giant and ultrashort pulsed-laser ***_(3)C_(2)T_(x)and Ti_(2)CT_(x)nanosheets however rapidly deteriorate under ambient conditions,limiting their *** paper demonstrates how excellent modulation depth of one of the MAX phase compounds vanadium zinc carbide(V_2ZnC)makes it a brilliant saturable absorber(SA)in passively Q-switched all-fiber pulsed lasers,integrated such that a 16.73-μm V_(2)ZnC-polyvinyl alcohol(PVA)thin film acts as SA in the *** and non-saturable absorptions were found to be 13.2%and 10.47%,while saturation optical intensity and modulation depth were 6.25 k W/cm^(2)and 12.43%,respectively,illustrating the optical *** superiority of MAX-PVA,fabricated in four distinct ratios,was demonstrated by the fact that it self-starts a giant pulsed laser at pump power as low as 22.5 mW and firmly accomplished 120.6 kHz repetition rate with a pulse width of 2.08μ*** is a fine SA for the use of pulsed-laser production using all-fiber laser due to fabrication simplicity and great optical,thermophysical,and mechanical qualities.

关键词： MAX Q-switched giant pulsed erbium-doped all-fiber laser with V_(2)ZnC MAX phase saturable absorber

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Creation of Multiple Subwavelength Focal Spot Segments Using Phase Modulated Radially Polarized Multi Gaussian Beam

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Chinese Physics Letters 2016年第9期33卷 48-51页

作者： K.Prabakaran K.B.Rajesh S.Sumathira M.D.Bharathi R.Hemamalini A.M.musthafa V.Aroulmoji Department of Physics Mahendra Arts and Science College(Autonomous) Department of Physics Chikkanna Government Arts College Department of Physics Sri Sarada College for Women(Autonomous) Department of General Studies(Physics Group) Jubail University College(Male Branch) Royal Commission of Jubail Center for Research and Development Mahendra Educational Institutions

Based on the vector diffraction theory, the effect of complex phase filters on intensity distribution of a radially polarized multi Gaussian beam in the focal region of high NA lens is theoretically investigated. It is observed that a properly designed multi belt complex phase filter can generate subwavelength novel focal patterns including splitting of focal spots and generation of multiple focal spot segments such as eight, six and four focal spots along the optical axis are obtained. We expect that such an investigation is useful for optical manipulation and material processing, multiple high refractive index particle trapping technologies.

关键词： of for Creation of Multiple Subwavelength Focal Spot Segments Using Phase Modulated Radially Polarized Multi Gaussian Beam on is in

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An Optimized Fuzzy Based Ant Colony Algorithm for 5G-MANET

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Computers, Materials & Continua 2022年第1期70卷 1069-1087页

作者： R.Nithya K.Amudha A.Syed musthafa Dilip Kumar Sharma Edwin Hernan Ramirez-Asis Priya Velayutham V.Subramaniyaswamy Sudhakar Sengan Department of Computer Science and Engineering Vivekananda College of Engineering for WomenTiruchengode637205Tamil NaduIndia Department of Electronics and Communication Engineering Kongunadu College of Engineering and TechnologyThottiam621215Tamil NaduIndia Department of Information Technology M.Kumarasamy College of EngineeringKarur639113Tamil NaduIndia Department of Mathematics Jaypee University of Engineering and TechnologyGuna473226M.P.India Business and Tourism Faculty Universidad Nacional Santiago Antunez De MayoloHuarazPeru Department of Computer Science and Engineering Paavai Engineering CollegeNamakkal637018Tamil NaduIndia School of Computing SASTRA Deemed UniversityThanjavur613401Tamil NaduIndia Department of Computer Science and Engineering PSN College of Engineering and TechnologyTirunelveli627152Tamil NaduIndia

The 5G demonstrations in a business has a significant role in today’s fast-moving *** in 5G,drives a wireless system intended at an enormously high data rate,lower energy,low latency,and *** this reason,routing protocols of MANET have the possibility of being fundamentally flexible,high performance,and *** 5G communication aims to afford higher data rates and significantly low Over-The-Air *** through supplementary ACO routing processes,a security-aware,fuzzy improved ant colony routing optimization protocol is proposed in *** goal is to develop aMANET routing protocol that could provide a stable packet transmission ratio,less overhead connectivity,and low end-to-end latency in shared standard scenarios and attack *** demonstrates effective results with hybrid architecture and proved to be effective than other state-of-the-art routing protocols of MANETs,like AODV,its routing organization implemented through Optimized Fuzzy based ACO Algorithm for ***-wavelengths are required to perform a significant role in *** research proposed to test the efficiency of MANET consisting of only mmWave User *** reduced packet transmission loss of UEs withmmWave,meaning well-transmitted SNR leads directly to a better packet delivery *** verify results,simulation using the NS-3 simulator mmWave module is used.

关键词： 5G attacks D2D communications MANET mmWave security

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Brain Tumor Retrieval in MRI Images with Integration of Optimal Features

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Journal of Harbin Institute of Technology(New Series) 2024年第6期31卷 71-83页

作者： N V Shamna B Aziz musthafa Department of Computer Science and Engineering PA College of EngineeringMangaluru 574153KarnatakaIndia Department of Computer Science and Engineering Bearys Institute of TechnologyMangaluru 5754199KarnatakaIndia

This paper presents an approach to improve medical image retrieval, particularly for brain tumors, by addressing the gap between low-level visual and high-level perceived contents in MRI, X-ray, and CT scans. Traditional methods based on color, shape, or texture are less effective. The proposed solution uses machine learning to handle high-dimensional image features, reducing computational complexity and mitigating issues caused by artifacts or noise. It employs a genetic algorithm for feature reduction and a hybrid residual UNet(HResUNet) model for Region-of-Interest(ROI) segmentation and classification, with enhanced image preprocessing. The study examines various loss functions, finding that a hybrid loss function yields superior results, and the GA-HResUNet model outperforms the HResUNet. Comparative analysis with state-of-the-art models shows a 4% improvement in retrieval accuracy.

关键词： medical images brain MRI machine learning feature extraction and reduction content-based image retrieval(CBIR)

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Silencing of Astrocyte Elevated Gene-1 (AEG-1) inhibits the proliferative and invasive potential through interaction with Exostosin-1 (EXT-1) in primary and metastatic colon cancer cells

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BIOCELL 2021年第3期45卷 563-576页

作者： SUSHMITHA SRIRAMULU SARUBALA MALAYAPERUMAL SUMAN K.NANDY ANTARA BANERJEE musthafa M OHAMED ESSA SARAVANABABU CHIDAMBARAM M.WALID QORONFLEH SURAJIT PATHAK Department of Medical Biotechnology Faculty of Allied Health SciencesChettinad Academy of Research and Education(CARE)Chettinad Hospital and Research Institute(CHRI)ChennaiIndia Bioinformatics Centre Department of RDAPNorth-Eastern Hill UniversityTuraIndia Department of Food Science and Nutrition CAMSSultan Qaboos UniversityMuscatOman Ageing and Dementia Research Group Sultan Qaboos UniversityMuscatOman Department of Pharmacology JSS College of PharmacyJSS Academy of Higher Education&ResearchMysuruIndia Research&Policy Department World Innovation Summit for Health(WISH)Qatar FoundationDohaQatar Q3CG Research Institute(QRI) Research&Policy DivisionYpsilantiMI 48917USA

Colon cancer is the third major cause of cancer deaths,accounting for about 8%in terms of mortality *** present study aims to explore the effect of silencing Astrocyte Elevated Gene-1(AEG-1),a metastasis mediating factor,and how it interacts with Exostosin-1(EXT-1)protein to inhibit the proliferative and invasive potential in colon cancer *** siRNA transfection was performed using AEG-1 siRNA in SW480 and SW620 colon cancer cell lines,and the expression levels of mRNA and protein were analyzed by Real-time PCR and Immunofluorescence.A simple bioinformatics approach was carried out to identify the possible interactions between AEG-1 and EXT-1 using Easy Networks and Pathway Commons *** survival and clonal efficiency were determined using Cell Counting Kit-8 assay and clonogenic assay,apoptosis using flow cytometry analysis,migration and invasion using scratch and Transwell assays,*** siRNA transfection significantly suppressed the expression of AEG-1 in mRNA and protein levels on SW480 and SW620 colon cancer *** our results,we found that EXT-1 mRNA and protein level was significantly upregulated in AEG-1 siRNA transfected ***,treatment with AEG-1 siRNA inhibited the proliferation,clonogenic ability,migration,and invasion and also induced *** the bioinformatic approach,our data analyses pointed towards the crosstalk between AEG-1 and EXT-1 mediated through Patched-1(PTCH-1)*** current results demonstrated that silencing AEG-1 can restrain cell proliferation,migration,and invasion,ultimately leading to *** AEG-1 siRNA transfected cells,PTCH-1 activity might be modulated by several genes and,in turn,affects the EXT-1 ***,these observations not only provide insight into the interplay between AEG-1 and EXT-1 but also suggest that AEG-1 may represent a possible candidate therapeutic target through interaction with EXT-1 in colon cancer.

关键词： Oncogene EXT-1 siRNA Colon cancer AEG-1

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Beneficial effects of date palm fruits on neurodegenerative diseases

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Neural Regeneration Research 2016年第7期11卷 1071-1072页

作者： musthafa Mohamed Essa Mohammed Akbar Mohammed Abdul Sattar Khan Department of Food Science and Nutrition College of Agriculture and Marine SciencesSultan Qaboos University Ageing and Dementia Research Group Sultan Qaboos University Section of Molecular Pharmacology and Toxicology Laboratory of Membrane Biochemistry and BiophysicsNational Institute on Alcohol Abuse and AlcoholismNational Institutes of Health Department of Anesthesia Critical Care and Pain MedicineShriners Hospitals for Children~?Massachusetts General Hospital and Harvard Medical School

Date palm tree（Phoenix dactylifera L.）is an important crop,which is cultivated in many countries extending from North Africa to the Middle East,including many of the GCC（Gulf Cooperation Council）Countries（Allaith... 详细信息

关键词： fruits Phoenix climatic cultivated Africa neuronal Middle amyloid poorly occlusion

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