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Memory impairment occurred in mice deficient for lipoprotein lipase（LPL）is probably caused by decrease of pre-synaptic vesicles

Memory impairment occurred in mice deficient for lipoprotein...

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中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： Colin ROSS Hayden mr George LIU Department of Medical Genetics University of British ColumbiaCentre for Molecular Medicine and TherapeuticsVancouverCanada Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences Ministry of Education

＜正＞Lipid and associated proteins play an important role in causing Alzheimer’s disease（AD） and other forms of *** pre-clinical and clinical researches suggested that cholesterol-lowering medicines could meliorate the memory impairment in established *** lipase（LPL）,an essential molecule in lipoprotein metabolism in tissues such as adipose tissue has also been detected in the *** previous studies suggested the possible relationship between LPL mutation and dementia,how LPL in brain influences learning and memory is ***,we used behavior tests,immunohistocheniistry,western blotting,transmission electron microscopy（TEM） and other methods to investigate the mechanism（s） of this memory impairment,using the LPL-Knockout mouse *** first found that LPL-deficient mice had severe hippocampus-dependent memory impairment with behavior tests of radial arm water maze and step-down inhibitory *** interestingly,remarkable decrease of pre-synaptic vesicles as well as their marker synaptophysin was observed in the hippocampi from this kind of animals,but there was no significant neuron *** investigation established the animal model of memory impairment with LPL deficiency for the first *** the decrease of pre-synaptic vesicles caused by the imbalance of lipid homeostasis in brain might be the main reason of memory impairment in LPL-KO mice.

关键词： lipoprotein lipase(LPL) LPL deficiency hippocampus memory impairment pre-synaptic vesicles lipid

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Chinese HR Strategyl Facing WTO

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中国周刊 2002年第2期 16-21页

作者： mr. Zhang Xuezhong, Minister of Ministry of Personnel

China’s entry into the WTO will push further the formation of an open-door environment to the outside world in all directions, multiple levels and wider fields, and it will deeply influence economic development. It also accords with our country’s long term and fundamental interests. But after our entry into the WTO, we should also have sufficient estimation of the challenges. The development of the economy and society mainly relies on human resources. As the central government’s economic conference pointed out, the resource in shortest supply in China is human resources. If we cannot resolve this problem, continued modernization will be seriously hampered and we will not be able to deal with the more open environment of our new situation. So in this case, from one point of view, entry into the WTO actually is an examination for the qualifications of government personnel and all kinds of talents in our

关键词： Chinese HR Strategyl Facing WTO HR

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Prospects of Chinas Economic Cooperation with the Asia-Pacific

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China International Studies 2014年第5期34卷 5-11页

作者： H.E. mr. Chen Yuan the National Committee of the Chinese People’s Political Consultative Conference (CPPCC)

The effective cooperation between China and the other Asia-Pacific The Asia-Pacific economies has brought about a booming regional economy and turned the Asia-Pacific region into an engine of global economic growth. In this address, mr. Chen Yuan also introduces China’s new round of reform and calls for a regional partnership that needs top-level designing, continued commitment to open regionalism, and financial cooperation.

关键词：经济合作中国展望太平洋区域性学术界

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理疗中连续被动运动的临床应用

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国外医学（物理医学与康复学分册） 1993年第2期13卷 81-83页

作者： Mccarthg mr 卢光增

本世纪70年代,Salter 提出滑液关节的连续被动运动(continuous passive motion,CPM),来促进关节组织的愈合。现在,应用已扩展到各种矫形外科情况,其指征包括下述膝关节情况的康复,多数关节内外骨折的固定、膝关节的软组织处理、膝关节... 详细信息

本世纪70年代,Salter 提出滑液关节的连续被动运动(continuous passive motion,CPM),来促进关节组织的愈合。现在,应用已扩展到各种矫形外科情况,其指征包括下述膝关节情况的康复,多数关节内外骨折的固定、膝关节的软组织处理、膝关节内外骨折的固定、膝关节的软组织处理、膝关节脓毒症,膝关节成形术、前十字韧带再建、膝伸肌机构的手术等。CPM 对软组织和关节面有独特的生理作用,但需进一步的临床研究以制定出适当的CPM 方案。本文旨在综述关于临床CPM 研究、动物的CPM 研究和CPM 在理疗中的可能应用。

关键词：理疗连续被动运动临床运动疗法

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