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Protective effects ofLactobacillus plantarum against epithelial barrier dysfunction of human colon cell line NCM460

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w.rld Journal of Gastroenterology 2010年第45期16卷 5759-5765页

作者： Mary Pat moyer INCELL Corporation San AntonioTX 78249United States

AIM: To investigate the effects of Lactobacillus plantarum (L. plantarum ) in the intestinal permeability and expression of tight junction (TJ) using the normal human colon cell line NCM460. METHODS: Paracellular permeability of NCM460 monolayers w.s determined by transepithelial electrical resistance and dextran permeability. Expression of TJ proteins in NCM460 cell monolayers w.s detected by w.stern blotting and quantitative real-time polymerase chain ***: L. plantarum played an important role in increasing transepithelial electrical resistance and decreasing the permeability to macromolecules of NCM460 monolayers against the disruption caused by enteropathogenic Escherichia coli (E. coli ) or enteroinvasive E. coli . L. plantarum also prevented the decrease in the expression of TJ proteins and F-actin in NCM460 ***: L. plantarum can protect against dysfunction of NCM460 intestinal epithelial barrier caused by enteropathogenic E. coli or enteroinvasive E. coli , and thus can be a potential candidate of therapeutic agents for the treatment of intestinal diseases.

关键词： Lactobacillus plantarum NCM460 Tight junction Intestinal barrier

Mdm proteins： critical regulators of embryogenesis and hornoeostasis

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Journal of Molecular Cell Biology 2017年第1期9卷 16-25页

作者： Sydney M. moyer Connie A. Larsson Guillermina Lozano Department of Genetics The University of Texas MD Anderson Cancer Center Houston TX 77030 USA

Mdm2 and Mdm4 are negative regulators of the tumour suppressor p53; hence, this relationship is the focus of many cancerrelated studies. A multitude of experiments across various developmental stages have been conducted to explore the tissuespecific roles of these proteins in the mouse. w.en Mdm2 or Mdm4 are deleted in the germiine or specific tissues, they display different phenotypic defects, some of w.ich lead to embryonic lethaLity. Mdm2 loss is often more deleterious than toss of its homotogue Mdm4. ALL tissues experience activation of p53 target genes upon toss of Mdm2 or Mdm4; how.ver, the degree to w.ich the p53 pathw.y is perturbed is highly tissue-specific and does not correlate to the severity of the morphological pheno- types. Therefore, a need for further understanding of how.these proteins regulate p53 activity is w.rranted, as therapeutic targeting of the p53 pathw.y is rapidly evoLving and gaining attention in the field of cancer research. In this review. w. discuss the tissue-specificity of Mdm proteins in regulating p53 and expose the need for investigation at the celt-specific level.

关键词： Mdm2 Mdm4 MdmX development embryogenesis tissue-specific p53

The psychology of friendship

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The psychology of friendship

It’s for the Greater Good: Perspectives on Maltreatment during Labor and Delivery in Rural Ghana

作者： Hojjat Mahzad moyer Anne

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Open Journal of Obstetrics and Gynecology 2014年第7期4卷 383-390页

作者： Jamila Yakubu Dana Benyas Sarah Vandy Emil Ebenezer Amekah richard Adanu Cheryl A. moyer Ghana Health Service Central Region Accra Ghana University of Ghana School of Public Health Accra Ghana University of Michigan Medical School Global REACH Ann Arbor USA University of Michigan School of Public Health Ann Arbor USA

Aim: Encouraging w.men to deliver in facility settings is one strategy to improve maternal and neonatal outcomes in the developing w.rld. How.ver, in much of sub-Saharan Africa, few.r than half of pregnant w.men deliver in health facilities. Fear of maltreatment during labor and delivery has been show. to be one barrier to facility delivery, yet previous studies have focused solely on reports from w.men, rarely seeking insights from practicing midw.ves. Method: All seven practicing midw.ves from a rural hospital in Ghana and ten pregnant w.men seeking antenatal care from the same hospital w.re recruited to participate in in-depth interview. regarding their perceptions of care during labor and delivery. A semi-structured interview.tool and qualitative field interview.ng approach w.re utilized. All interview. w.re audio taped, transcribed, and analyzed using NVivo 9.0. Results: Respondents described situations that precipitate abuse during facility deliveries, yet not all abuse w.s seen as acceptable. Tw. overarching themes emerged: 1) The interaction betw.en midw.ves and their patients is analogous to a mother/daughter relationship, including both a know.edge imbalance and the need for disciplinary action w.en necessary;and 2) Midw.ves feel a strong sense of responsibility for the delivery outcomes and as a result, they w.ll do w.atever it takes to deliver a live baby to a healthy mother. Hitting, yelling, and neglecting w.men w.re reported as common occurrences in the labor and delivery w.rd. How.ver, each w.s undertaken to encourage w.men to do w.at w.s needed to deliver safely. Conclusion: These findings suggest that the issue of patient maltreatment in low.resource labor and delivery settings is complex and may be undertaken in w.at is perceived to be the laboring w.man’s best interest. The exploration of alternative strategies to facilitate labor and delivery is w.rranted, as w.ll as the provision of adequate support and resources for practicing midw.ves in rura

关键词： Maltreatment Midw.ves Pregnancy w.st Africa Delivery Care Developing Countries

Establishing Legumes in a Tall Fescue Sw.rd

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American Journal of Plant Sciences 2015年第2期6卷 355-361页

作者： Doo-Hong Min Joseph L. moyer Department of Agronomy Kansas State University Manhattan KS USA Southeast Agricultural Research Center Kansas State University Parsons KS USA

Tall fescue [Schedonorus arundinaceus (Schreb.) Dumort.] is a common grass species in the eastern half of the USA, but legumes grow. w.th it could provide benefits. Obstacles to legume establishment in fescue pastures include disease, insect damage, and grass competition. Experiments w.re performed in 2010 and 2011 at Site 1 to test the efficacy of insect control, disease control, and tw. methods of grass suppression on seedling establishment of three legumes. The highest seedling density of red clover (Trifolium pretense L.) w.s obtained w.th glyphosate treatment regardless of pest control and for clipping w.thout pest control. No overall or consistent benefit w.s found for w.ite clover (Trifolium pretense L.) or trefoil (Lotus corniculatus L.) from seed and foliar insecticides or fungicides, or for grass suppression by either clipping or glyphosate application. Experiments w.re performed in 2012 and 2013 at Site 2 to test the efficacy of grass suppression by grazing cattle or by clethodim application. Seedling density of red clover w.s not significantly improved by either treatment, but the density of birdsfoot trefoil w.s increased by clethodim, and the density of w.ite clover w.s increased in 2013 by both methods of grass suppression. Overall, red clover w.s least sensitive to grass competition. Birdsfoot trefoil w.s better served by the immediate effect of chemical suppression, w.ereas w.ite clover benefitted most from the lengthier grass suppression provided by grazing.

关键词： Red Clover w.ite (Ladino) Clover Birdsfoot Trefoil Herbicide Grazing

Peridynamic Solutions for Timoshenko Beams

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Engineering（科研） 2014年第6期6卷 304-317页

作者： E. Thomas moyer Michael J. Miraglia Naval Surface w.rfare Center/Carderock Division W. Bethesda USA

Peridynamics is a recently developed formulation for continuum mechanics w.ich describes material deformation using a nonlocal approach. Unlike Classical Continuum Mechanics (CCM) w.ere the conservation equations are cast into partial differential equations, Peridynamics describes the deformation in terms of integro-differential equations. Additionally, peridynamics permits a natural length scale that is absent in CCM. This facilitates the modeling of complex material behavior and fracture w.ich is not dependent on the numerical discretization length scale. In this paper, w. develop a Peridynamic formulation for a Timoshenko beam. Full details and numerical examples are presented for both bending and axial behavior. w.ile the development in this paper is limited to elastic, infinitesimal deformations, the approach can be extended to finite inelastic deformations.

关键词： Peridynamics Timoshenko Beam Beam Bending Dynamic Deformation

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甘薯的病毒和类病毒病害

园艺与种苗 1990年第3期 42-44页

作者： J.w.moyer 王锡锋

国际农业社会对甘薯的重新关注,致使对原始种质和改良种质的交换需求发生了显著的增加。据联合国粮农组织估计,甘薯在世界作物总产中居第七位。健全的园艺管理和国家检疫条例要求,进行国际分发的甘薯种质不能携带已知的病毒。此外,甘薯... 详细信息

国际农业社会对甘薯的重新关注,致使对原始种质和改良种质的交换需求发生了显著的增加。据联合国粮农组织估计,甘薯在世界作物总产中居第七位。健全的园艺管理和国家检疫条例要求,进行国际分发的甘薯种质不能携带已知的病毒。此外,甘薯的生产和研究也需

关键词：甘薯株系粉虱病原物巴西牵牛病原体 SPFMV 甘薯病毒病毒传染病传染病病毒病

《Blackw.ll双语与多语研究方法指导手册》介绍

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当代语言学 2012年第3期14卷 314-316页

作者：李嵬 Melissa G.moyer 阎喜不详澳门大学社会科学及人文学院英文系中国澳门999078

《Blackw.ll双语与多语研究方法指导手册》（The Blackw.ll Guide to Research Methods in Bilingualism and Multilingualism）由Li w.i（李嵬）和***编辑，Black w.ll出版社2008年出版。本书分为三大部分，共22章。下面对其内容进行... 详细信息

关键词：手册双语 Black 2008年 w.ll 出版社

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发展新能源技术对测量的要求

中国检验检测 1981年第6期 3-4页

作者： J.w.moyer 康金玉

几乎每个从事能源工业的人(实际上是那些比以往任何时候对能源更感兴趣的更多人)将一致同意目前唯一的问题是:如果这个国家想在国际社会中保持较高的生活水平及安全地位,那么它在能源领域中必须采取的方向(与过去大约十年所追求的不同)... 详细信息

几乎每个从事能源工业的人(实际上是那些比以往任何时候对能源更感兴趣的更多人)将一致同意目前唯一的问题是:如果这个国家想在国际社会中保持较高的生活水平及安全地位,那么它在能源领域中必须采取的方向(与过去大约十年所追求的不同)是什么?

关键词：能源工业装置盐水