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Assessment of Total Incapacity for Work or Incapacity in the Criminal Sense in Case of Penetrating Wounds of the Neck

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Forensic Medicine and Anatomy Research 2018年第1期6卷 1-9页

作者： El Hadji Oumar Ndoye Bobo Diallo Sidy Ahmed Dia mouhamed Manibiliot Soumah Mame Coumba fall Mor Ndiaye Department of Forensic and Labor Medicine University Cheikh Anta Diop (UCAD) Dakar Senegal ENT Department of the University Hospital Center of Fann Dakar Senegal

Penetrating wounds of the neck are often life-threatening. The victims are exposed to vascular and laryngotracheal lesions. The purpose of this work is to report the various aspects of the management of penetrating wounds in our context and to make the medico-legal assessment of incapacity in the criminal sense or total incapacity for work. This is a retrospective study (2002-2014) on thirty-nine (39) cases of penetrating neck wounds, received at the ENT departments of the Aristide Le Dantec and Fann University Hospital Centers. Patients were predominantly male, representing 94% of cases with an average age of 27 years. Seventy (70%) of the accidents occurred in the region of Dakar. In 42% of cases, the circumstance of occurrence was a fight or an assault. The weapon used in most cases by the aggressor was a cutter or a knife. The average waiting time was 37 hours with extremes of 02 and 216 hours. Surgically, all patients had been examined under general anesthesia. In terms of lesions, 37 cases had profound cervical muscle injuries, i.e. 94%. There were 17 vascular lesions (43%). The medico-legal distribution of patients showed that among them, 10% had a total incapacity to work exceeding 21 days. The determination of total incapacity for work is an important medical procedure that requires capability and experience. The doctor must not fall into the trap of the confusion between the TIW on the criminal level and the TIW on the civil level. He must limit medically and should not make judgments.

关键词： Penetrating Neck Wounds Assessment of Total Incapacity for Work Criminal Incapacity Forensic Medicine

Conservative Approach Might Be the Strategy by Default in Stable Angina Patients: A Case Report

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World Journal of Cardiovascular Diseases 2020年第11期10卷 769-774页

作者： Serigne Cheikh Tidiane Ndao Mame Madjiguene Ka Djibril Marie Ba Khadidiatou Dia mouhamed Chérif Mboup Pape Diadie fall Department of Cardiology Hospital Principal Dakar Dakar Senegal

Management of stable angina is still a matter of debate. Whether a conservative or invasive approach is better remains unclear. Even though recent large-scale randomized trials depict the conservative strategy as safe and efficient. In this report, we present a case of a 53-year-old male patient with cardiovascular risk factors of hypertension and hypercholesterolemia. He complained about typical chest pain at exertion. The coronary angiogram (CA) revealed severe stenosis of the proximal left anterior descending artery (LAD) ostium. After heart team discussion, coronary artery bypass graft (CABG) was advocated. However, due to a lack of means, the CABG was postponed. Meanwhile, he was managed with guideline-based medical therapy. In addition, he exercised regularly and adopted a healthy diet. Evolution was favorable with excellent symptoms control. A regular follow-up was organized with his cardiologist. A new CA before an eventual CABG six years later showed a significant plaque volume regression of the proximal LAD. We decided to continue conservative management. The stress echocardiogram to assess symptoms and exercise tolerance was normal. Our patient was sent to surgery on top of optimal medical therapy even though angioplasty was a good indication and was feasible. However, while he was struggling to afford the CABG procedure, he adopted a very healthy lifestyle along with medical therapy. Six years later, the result of that approach was without appeal, suggesting and reinforcing the conservative management

关键词： Stable Angina Chronic Coronary Syndrome Conservative Treatment Case Report

Impact of viscosity modifier on asphalt properties used for bus rapid transit lanes in Chengdu

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Journal of Modern Transportation 2017年第3期25卷 185-193页

作者： mouhamed Bayane Bouraima Xiaohua Zhang Shuiwen Zhou Yanjun Qiu School of Civil Engineering Southwest Jiaotong Univ.Highway Engineering Key Laboratory of Sichuan Province Sichuan Provincial Transport Department Highway Planning Survey Design and Research Institute

In order to find the effect of different viscosity modifier dosages on asphalt binder＇s performance in bus rapid transit lanes in the city of Chengdu, three different viscosity modifiers were analyzed： TAFPACK-super （TPS）, high-viscosity additive （HVA） and road-science- technology （RST）, and four different asphalt binders were investigated through laboratory experiments. The percent- ages of the viscosity modifiers used were： TPS （0%, 8%, 10%, 12%, 14% and 16%） and RST and HVA （8% and 12%） depending on the type of asphalt binder. Technical indicators of modifier asphalt were tested through con- ventional and unconventional binder tests. It has been found out that only a percentage greater than or equal to 14% TPS is reasonable to achieve the requirement set by 20,000 Pa. s for the 60℃ dynamic viscosity on local #70 grade asphalt. The results indicate that conventional bin- ders did not meet the requirements of the 60℃ dynamic viscosity when 12% of TPS or HVA modifiers were used. In addition, the B-type styrene-butadienne-styrene （SBS） modified asphalt binder has better viscosity balance than the A-type SBS modified when 8% of each of the three different kinds of viscosity modifiers is used. Therefore, the B-type modified SBS thus appears to be a suitable choice in asphalt mixtures for bus rapid transit lane with the 60℃ dynamic viscosity.

关键词： High-viscosity modifier Physical properties 60℃ dynamic viscosity Bus rapid transit lane

Cardiovascular benefits from SGLT2 inhibition in type 2 diabetes mellitus patients is not impaired with phosphate flux related to pharmacotherapy

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World Journal of Cardiology 2021年第12期13卷 676-694页

作者： mouhamed Nashawi Mahmoud S Ahmed Toka Amin Mujahed Abualfoul Robert Chilton Department of Internal Medicine Baylor Scott and White All Saints Medical CenterFort WorthTX 76132United States Division of Medicine-Cardiology UT Health San AntonioSan AntonioTX 78229United States Department of Internal Medicine Faculty of MedicineCairo UniversityDallasTX 75203United States Department of Internal Medicine Methodist Dallas Medical CenterDallasTX 75203United States

The beneficial cardiorenal outcomes of sodium-glucose cotransporter 2 inhibitors(SGLT2i)in patients with type 2 diabetes mellitus(T2DM)have been substantiated by multiple clinical trials,resulting in increased interest in the multifarious pathways by which their mechanisms *** principal effect of SGLT2i(-flozin drugs)can be appreciated in their ability to block the SGLT2 protein within the kidneys,inhibiting glucose reabsorption,and causing an associated osmotic *** ameliorates plasma glucose elevations and the negative cardiorenal sequelae associated with the *** include aberrant mitochondrial metabolism and oxidative stress burden,endothelial cell dysfunction,pernicious neurohormonal activation,and the development of inimical *** outcomes within these domains have been validated with SGLT2i ***,by modulating the sodium-glucose cotransporter in the proximal tubule(PT),SGLT2i consequently promotes sodium-phosphate cotransporter activity with phosphate ***,even at physiologic levels,poses a risk in cardiovascular disease burden,more so in patients with type 2 diabetes mellitus(T2DM).There also exists an association between phosphatemia and renal impairment,the latter hampering cardiovascular function through an array of physiologic roles,such as fluid regulation,hormonal tone,and ***,increased phosphate flux is associated with an associated increase in fibroblast growth factor 23 levels,also detrimental to homeostatic cardiometabolic function.A contemporary commentary concerning this notion unifying cardiovascular outcome trial data with the translational biology of phosphate is scant within the *** the apparent beneficial outcomes associated with SGLT2i administration notwithstanding negative effects of phosphatemia,we discuss in this review the effects of phosphate on the cardiometabolic status in patients with T2DM and cardiorenal disease,as well as the

关键词： Sodium-glucose cotransporter 2 Phosphate Hyperphosphatemia Cardiovascular Canagliflozin Dapagliflozin Empagliflozin Endothelial

Synergistic Effect of Halloyosite Nanotube and Nanocellulose on Thermal and Mechanical Properties of Poly(Ethylmethacrylate-co-Acrylonitrile)Bionanocomposites

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Journal of Renewable Materials 2020年第3期8卷 301-317页

作者： Karima Ben Hamou Amal Kadimi Remo Merijs Meri Sergei Gaidukov Hamid Kaddami Mustapha Raihane mouhamed Lahcini Fouad Erchiqui Laboratory of Organometallic and Macromolecular Chemistry-Composites Materials Faculty of Sciences and Technology of MarrakechCadi Ayyad UniversityGuélizAv.A.El KhattabiMarrakechBP 618Morocco Engineering School University of Québec in Abitibi-Témiscamingue445 Boulevard de l'UniversitéRouyn-NorandaJ9X 5E4QuébecCanada Institute of Polymer Materials Riga Technical UniversityKaļķu iela 1Centra rajonsRīgaLV-1658Latvia

This work reports a comprehensive study on poly(Ethylmethacrylateco-Acrylonitrile)Poly(EMA-AN)nanocomposites reinforced with a hybrid mixture of nanoreiforcements based on nanocrystals of cellulose(NCC)(1 or 5%wt)and halloysite nanotubes(HNTs)(1 or 5%wt).The morphology,thermal and mechanical properties of these nanocomposites were *** dispersion of the nanofillers has been shown by scanning electron microscopy.A significant increase of the rubbery modulus and glass transition temperature were obtained upon filler addition,due to the reduction of mobility of the matrix macromolecular *** the other hand,compared with the neat Poly(EMAAN),the storage modulus of the nanocomposites increased by a factor 38 when adding 5 wt%NCC and by 17 for the same concentration of *** properties of ternary nanocomposites were furthers increased resulting from a synergistic effect of these two nanofillers.

关键词： Poly(Ethylmethacrylate-co-Acrylonitrile) nanocrystals cellulose halloysite nanotubes nanocomposites hybrid mechanical properties

Sex Differences in Clinical and Angiographic Characteristics in Acute Coronary Syndrome Patients in Dakar, Senegal

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World Journal of Cardiovascular Diseases 2022年第7期12卷 403-413页

作者： Serigne Cheikh Tidiane Ndao Mame Madjiguene Ka Waly Niang Mboup Aimé Gildas Portella Khadidiatou Dia Pape Diadie fall mouhamed Chérif Mboup Department of Cardiology Hospital Principal Dakar Dakar Senegal

Background: Coronary artery disease (CAD) is in relentless progression, along with the adoption of western lifestyle in sub-Saharan Africa. In Senegal, the incidence of acute coronary syndrome (ACS) rose from 5% to 12% in Dakar during the last 20 years. That increase was observed in both women and men, and according to current data, the former paid the heaviest price in terms of mortality compared to men. In this study, we aim to retrospectively assess the clinical characteristics and angiographic profile of ACS in women compared to men in two tertiary care centers in Dakar. Methods: In this study, we retrospectively analyzed and compared data between men and women among 133 patients who underwent coronary angiogram for ACS in 2 tertiary centers from February 2019 to January 2020. Results: A total of 133 patients were included in our study of whom 97 (72.9%) were men. The mean age was 58 ± 13.6 years. Women were older than men (61.4 ± 14.3 years vs 56.6 ± 13.5 years (p = 0.07). Hypertension, sedentary lifestyle and obesity were significantly more frequent in women (69.4%, 52.7% and 19.4%) when compared to men (38.8%, 25.7% and 6.19%) respectively, (p = 0.001;0.002 and 0.03). Smoking was less frequent in women (2.8%) than in men (44.3%), (p Conclusion: In our study, women with ACS were older, had more cardiovascular risk factors but less angiographic extent of disease than men.

关键词： Sex Differences Acute Coronary Syndrome Senegal

Isolated esophageal tuberculosis:A case report

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World Journal of Gastrointestinal Endoscopy 2022年第9期14卷 575-580页

作者： Ibrahima Diallo Omar Touré Elhadji Souleymane Sarr Abdoul Sow Bineta Ndiaye Papa Silman Diawara Cherif mouhamed Dial Ababacar Mbengue Fatou fall Hepato-Gastroenterology Hopital Principal de DakarDakar 3006Senegal Hepatogastroenterology Hopital Principal de DakarDakar 3006Senegal Department of Pathology Hopital Principal de DakarDakar 3006Senegal Department of Biology Hopital Principal de DakarDakar 3006Senegal Department of Pathology Hopital Général Idrissa PouyeDakar 3006Senegal Department of Imaging Hopital Principal de DakarDakar 3006Senegal

BACKGROUND Tuberculosis is endemic in *** its extra-pulmonary localization is rare,esophageal tuberculosis,particularly the isolated form,is *** report here a case of isolated esophageal tuberculosis in an immunocompetent *** SUMMARY A 58-year-old man underwent consultation for mechanical dysphagia that had developed over 3 mo with non-quantified weight loss,anorexia,and *** digestive endoscopy showed extensive ulcerated lesions,suggesting *** diagnosis was confirmed by histopathology,which showed gigantocellular epithelioid granuloma surrounding a caseous *** computed tomography scan did not show another localization of the *** outcome was favorable with *** Esophageal tuberculosis should be considered when dysphagia is associated with atypical ulcerated lesions of the esophageal mucosa,in an endemic area.

关键词： Tuberculosis Esophagus Endoscopy Case report

Pulmonary <i>Aspergillus fumigatus</i>and <i>Cryptococcus neoformans</i>Co-Infection on an Underlying Sarcoidosis Condition: Report of a Rare Case

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Open Journal of Internal Medicine 2019年第2期9卷 26-34页

作者： Todejohanyta Lucette Arcady Ahouandogbo Biramcodou fall Ahmadou Gaye Mabom Walahalaindimitri Lé on Birwe Mankré o mouhamed Mbar Niang Ahmadou fall Cissé Rizk Kré o Claire Sandrine Ngono Boundia Djiba Awa Cheikh Ndao Souhaibou Ndongo Senegalese Society of Internal Medicine Hospital LE DANTEC Dakar Senegal Dakar Senegal French National Society of Internal Medicine French Society of Rheumatology Dakar Senegal

Sarcoidosis is a systemic granulomatosis from an unknown etiology, particularly affecting the lungs and the lymphatic system. It is associated with an immune deficiency involving an excessive immune response mediated by TH1 lymphocytes. Its evolution can lead to serious complications such as pulmonary fibrosis, pulmonary hypertension, bronchial stenosis and opportunistic infections. Opportunistic infections rarely occur on an underlying sarcoidosis condition. We report a rare case of pulmonary aspergillary and cryptococcal co-infection, on a patient with sarcoidosis who was finally lost to follow up. It was about a 47 years old female patient, diagnosed in 2015 for mediastino-pulmonary and neurological sarcoidosis. She was in therapeutical rupture after a 3-month period of corticotherapy at a dosage of 20 mg daily. The patient has been lost of sight for 3 years and was seen again on November, 22nd, 2018 at the Internal Medicine/Rheumatology Department of DALAL JAMM Hospital. At his admission she presented: a low grade hemoptysia, a chronic cough, a shortness of breath on exertion CRD Stage 2. At the biological investigation, the CRP was at 71.9 mg/l. Calcium serum levels were at 102.6 mg/l. Sputum culture and AFBS were negative. The screening serology of aspergillary Ig G was positive at 12.4 UA/ml. Thoracic High Resonance CT pointed suggests a Stage 2 Sarcoidosis complicated with aspergillary graft. The bronchoscopy showed out a severe suppurated bronchopathy. Microscopic examination of the BAF found some Cryptococcus neoformans settlement. We concluded a diagnosis of pulmonary aspergilloma and cryptococcosis co-infection with an underlying condition of Stage 2 Sarcoidosis. We successfully treated our patient with an oral intake of Itraconazole at a dosage of 400 mg daily over a period of 10 days. This is a rare and life-threatening triple association. In our case, the patient was lost to follow up for a long period and this was considered as the first morbidity ri

关键词： Sarcoidosis Infection Cryptococcus Aspergillus

Pulmonary Embolism in Young Patients: About 24 Cases at the Cardiology Department of Dakar Principal Hospital in Senegal

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World Journal of Cardiovascular Diseases 2019年第9期9卷 632-638页

作者： Joseph Salvador Mingou Amadou Tidjani Saadou Madjiguene Ka Zoumana Sangaré Serigne Cheikh Tidiane Ndao Khadidiatou Dia mouhamed Cherif Mboup Pape Diadié fall Department of Cardiology Hospital Principal Dakar Senegal Departement of Cardiology Hospital Aristide Le Dantec Dakar Senegal

Introduction: Pulmonary embolism is a relatively common life-threatening cardiovascular emergency. It remains a diagnostic problem because of its nonspecific clinical signs. Objective: The general objective was to study pulmonary embolism in young patients admitted to the cardiology department of Dakar Principal Hospital in Senegal. Methodology: This was a retrospective, descriptive and analytical study in the cardiology department of the Dakar Principal Hospital over a period of two (02) years from January 1, 2015 to December 31, 2016 in young patients admitted for pulmonary embolism. Results: We collected 24 patients with a hospital prevalence of 2.18%. The average age was 42.29 years ± 8.41 years with a male predominance (sex ratio of 1.6). The Wells probability score was low in 54.16% of patients and medium in 45.83%. Functional signs were dominated by chest pain (83.33% of cases) followed by dyspnea (79.16% of cases). The thromboembolic risk factors found were gynecological-obstetrical in 16.6% of cases followed by prolonged bed rest. One case of thrombophilia was present with a deficiency of protein C and antithrombin III. The electrocardiogram recorded sinus tachycardia in 29.16% of patients;the Mac Ginn White sign (S1Q3T3) was found in 25% of cases. Echocardiography showed pulmonary arterial hypertension in 12.48% of cases, dilation of the right ventricle and a paradoxical septal motion in 14.28% of cases. CT pulmonary angiography showed 63.63% of cases with bilateral pulmonary embolism;it was unilateral in 22.72% of cases. Long-term anticoagulation was based on acenocoumarol 4 mg (66.7%) and Rivaroxaban (33.3%). 62.5% of the patients were seen at the 3rd month, when a checking was made to evaluate the tolerance of the treatment, and the evolution of the patient. Conclusion: Pulmonary embolism is not a rare condition in young subjects but is often underdiagnosed. Gyneco-obstetrical factors are predominant in this age group. Direct oral anticoagulants are mor

关键词： Pulmonary Embolism Young Patients Dakar (Senegal)