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Full-ter. pr.gnancy in br.ast cancer.sur.ivor.with fer.ility pr.ser.ation: A case r.por. and r.view of liter.tur.

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Wor.d Jour.al of Clinical Cases 2019年第1期7卷 58-68页

作者： Mar.a Gar.ido-Mar.n Pedr. Mar.a Ar.acha Luís Fer.ández Flor.ncia molfino Fina Mar.ínez-Soler.Avelina Tor.osa Pepita Gimenez-Bonafé Depar.ment of Physiological Sciences Physiology Unit Faculty of Medicine and Health Sciences Bellvitge Campus Universitat de BarcelonaIDIBELL L’Hospitalet del Llobregat Hospital Univer.itar. Gener.l de Catalunya Ser.icio de Oncología Médica Consorcio Corporación Sanitaria Parc Taulí Instituto de r.pr.ducción Cefer Depar.ment of Basic Nur.ing Faculty of Medicine and Health Sciences Universitat de Barcelona IDIBELL L’Hospitalet del Llobregat

A 43-year.old woman with an associated histor. of gynecological pathology and br.ast cancer.with only one cr.opr.ser.ed embr.o wished to be a *** factor. that influenced the success of the pr.gnancy in this case wer. analyzed. Favor.ble factor. included: tr.ple positive br.ast cancer.[positive hor.one r.ceptor. and positive human epider.al gr.wth factor.r.ceptor.2],which is mor. hor.osensitive and chemosensitive; absence of metastasis; cor.ect endometr.um pr.par.tion; and the patient's optimistic attitude and str.ct health habits. In contr.st, the factor. against success wer.: br.ast cancer. adjuvant br.ast cancer.ther.py gonadotoxicity; the age of the patient(> 40-year.old);endometr.osis; ovar.an cyst; hydr.salpinx; submucosal fibr.ids and the r.spective associated sur.er. done for.the above-mentioned pathology(all r.solved pr.or.to the embr.o tr.nsfer.; and a low quantity of ovules(low ovar.an r.ser.e) after.ovar.an stimulation. This is a ver. special clinical case of a patient with theor.tically low pr.gnancy success pr.bability due to the consecutive accumulation of gynecological and oncological pathologies, who nonetheless became pr.gnant and deliver.d a full-ter. infant and was able to pr.vide adequate br.astfeeding.

关键词： Br.ast cancer Fer.ility pr.ser.ation Gonadotoxicity Pr.gnancy In vitr. fer.ilization Hydr.salpinx Endometr.osis Case r.por.

r.cur.ence in node-negative advanced gastr.c cancer.Novel findings fr.m an in-depth pathological analysis of pr.gnostic factor. fr.m a multicentr.c ser.es

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Wor.d Jour.al of Gastr.enter.logy 2017年第45期23卷 8000-8007页

作者： Gian Luca Baiocchi Sar.h molfino Car.a Bar.nchelli Simone Giacopuzzi Daniele Mar.elli Paolo Mor.agni Mar.a Bencivenga Luca Sar.goni Car.a Vindigni Nazar.o Por.olani Mar.stella Botticini Giovanni De Manzoni Depar.ment of Clinical and Exper.mental Sciences University of Brescia Depar.ment of Pathology Spedali Civili di Brescia 1st Depar.ment of Gener.l Sur.er. Borgo Trento HospitalUniversity of Verona Depar.ment of Human Pathology and Oncology Surgical OncologyUniversity of Siena Depar.ment of Gener.l Sur.er. Morgagni-Pierantoni Hospital Depar.ment of Pathology Morgagni-Pierantoni Hospital Depar.ment of Pathology Azienda Ospedaliera Universitaria Senese IGIEr Università Bocconi

AIM To analyze the clinicopathological char.cter.stics of patients with both node-negative gastr.c car.inoma and diagnosis of r.cur.ence dur.ng follow-up. METHODS We enr.lled 41 patients tr.ated with cur.tive gastr.ctomy for.p T2-4 a N0 gastr.c car.inoma between 1992 and 2010,who developed r.cur.ence(Gr.up 1). We r.tr.spectively selected this gr.up fr.m the pr.spectively collected database of 4 center. belonging to the Italian r.sear.h Gr.up for.Gastr.c Cancer.and compar.d them with 437 p T2-4 a N0 patients without r.cur.ence(Gr.up 2). We analyzed lymphatic embolization,micr.vascular.infiltr.tion,per.neur.l infiltr.tion,and immunohistochemical deter.ination of p53,Ki67,and HEr. in Gr.up 1 and in a subgr.up of Gr.up 2(Gr.up 2 bis) of 41 cases matched with Gr.up 1 accor.ing to demogr.phic and pathological char.cter.stics. r.SULTS T4 a stage and diffuse histotype wer. associated with r.cur.ence in the gr.up of p N0 patients. In-depth pathological analysis of two homogenous gr.ups of p N0 patients,with and without r.cur.ence dur.ng longter. follow-up(gr.ups 1 and 2 bis),r.vealed two str.king patter.s: lymphatic embolization and per.neur.l infiltr.tion(two par.meter. that pathologists can easily r.por.),and p53 and Ki67,r.pr.sent significant factor. for.*** The r.por.ed pathological featur.s should be consider.d pr.dictive factor. for.r.cur.ence and could be useful to str.tify node-negative gastr.c cancer.patients for.adjuvant tr.atment and tailor.d follow-up.

关键词： N0 gastr.c cancer r.cur.ence Pr.gnostic factor. Pathological analysis Lymphatic embolization Per.neur.l infiltr.tion p53 Ki67

Analytic Differ.ntial Kinematics of Tetr.hedr.l Mechanisms

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Analytic Differential Kinematics of Tetrahedral Mechanisms

第十五届中国机构与机器科学国际学术会议

作者： Matteo Zoppi r.zia M. molfino PMAr.ab Univer.ity of Genova via Oper. pia 15A 16145GenovaItaly. PMAr.ab Univer.ity of Genova via Oper. pia 15A 16145GenovaItaly.

＜正＞The paper.pr.poses an analytical for.ulation for.the fir.t and second-or.er. for.ar. differ.ntial kinematics of the tetr.hedr.l mechanisms, a class of 3dof, tr.nslational par.llel ar.hitectur.s. This class gather. some well known ar.hitectur.s of pr.ctical inter.st, e.g., the 3UPU, the 3r.U and the 3PUU ar.hitectur.s assembled to be pur.ly tr.nslational. The standar. method to compute the end-effector.velocity and acceler.tion of some tetr.hedr.l mechanisms consists of der.ving the loop-closur. equations one/two times in the time var.able, in or.er.to obtain new systems of equations in the unknown components of the end-effector.velocity/acceler.tion, aztd solving again. The pr.sent paper.pr.vides the analytical and fully par.metr.c expr.ssions of such solutions. In par.icular. Jacobian and Hessian ar. obtained. The expr.ssions pr.posed can pr.vide useful insights for.the design of tetr.hedr.l mechanisms and can be used in r.bot contr.l.

关键词： Tr.nslational par.llel mechanisms Tetr.hedr.l mechanisms Differ.ntial kinematics Jacobian Hessian

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洞察欧洲机器人产业前沿发展

机器人产业 2018年第5期 38-44页

作者： r.zia molfino 意大利机器人及自动化协会

以机器人为代表的新一轮科技变革风潮,正快速改变当今社会的生产生活方式.从工业生产场景到生活服务场景,随处可见机器人的身影,它正以前所未有的速度融入经济发展的方方面面,并逐渐成为经济增长的新支点.欧洲作为世界经济最发达的地区... 详细信息

以机器人为代表的新一轮科技变革风潮,正快速改变当今社会的生产生活方式.从工业生产场景到生活服务场景,随处可见机器人的身影,它正以前所未有的速度融入经济发展的方方面面,并逐渐成为经济增长的新支点.欧洲作为世界经济最发达的地区之一,在过去的每一次工业革命浪潮中都担负起了“领头羊”的角色.如今,面对浩浩荡荡的新变革,这片孕育创新的沃土自然不会“隐匿江湖”,相反,这里的学者正在加速推进技术落地,助力产业转型升级,以钻研的姿态立足于科技前沿,奋力书写新的成绩.

关键词：机器人产业欧洲地平线欧盟解读工业生产科技前沿生活服务

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解读欧盟“地平线2020计划”对机器人产业发展的影响

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机器人产业 2018年第5期 40-44页

作者： r.zia molfino 意大利机器人及自动化协会

2017年12月,欧盟发布了"地平线2020计划"2018—2020年阶段的研发计划,这是该计划自2014年实施以来发布的第三期,也是最后一期计划项目。在2018世界机器人大会上,意大利机器人及自动化协会主席、欧盟委员会顾问r.zia molfino首先分析了... 详细信息

2017年12月,欧盟发布了"地平线2020计划"2018—2020年阶段的研发计划,这是该计划自2014年实施以来发布的第三期,也是最后一期计划项目。在2018世界机器人大会上,意大利机器人及自动化协会主席、欧盟委员会顾问r.zia molfino首先分析了欧洲工业的发展情况,然后就"地平线2020计划"及其新方向和影响做出了分析和解读。她指出,工业是欧洲经济的核心,"地平线2020计划"能够利用科技创新促进欧洲工业的可持续发展。

关键词：机器人地平线

Incr.ased r.sk of second malignancy in pancr.atic intr.ductal papillar. mucinous tumor.: r.view of the liter.tur.

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Wor.d Jour.al of Gastr.enter.logy 2015年第23期21卷 7313-7319页

作者： Gian Luca Baiocchi Sar.h molfino Bar.ar. Fr.ttoli Gr.ziella Pigozzi Feder.co Gheza Giacomo Gaver.ni Antonio Tar.sconi Chiar. r.cci Fr.ncesco Ber.agna Luigi Gr.zioli Guido AM Tiber.o Nazar.o Por.olani Depar.ment of Medical and Sur.ical Sciences Surgical Clinic University of Brescia 1~(st) Depar.ment of r.diology Brescia Civil Hospital Depar.ment of Medical and Sur.ical Sciences Gastroenterological Unit University of Brescia Depar.ment of Sur.ical Specialties Radiological and Forensic Sciences Nuclear Medicine SectionUniversity of Brescia

AIM: To analyze the available evidence about the r.sk of extr.pancr.atic malignancies and pancr.atic ductal adenocar.inoma associated to pancr.atic intr.ductal papillar. mucinous tumor.(IPMNs).METHODS: A systematic sear.h of liter.tur. was under.aken using MEDLINE, EMBASE, Cochr.ne and Web-of-Science libr.r.es. No limitations for.year.of publication wer. consider.d; pr.fer.nce was given to English paper.. All r.fer.nces in selected ar.icles wer. fur.her.scr.ened for.additional publications. Both clinical ser.es and Liter.tur. r.views wer. selected. For.all eligible studies, a standar. data extr.ction for. was filled in and the following data wer. extr.cted: study design, number.of patients, pr.valence of pancr.atic cancer.and extr.pancr.atic malignancies in IPMN patients and contr.l gr.ups, if ***: A total of 805 abstr.cts wer. selected and r.ad; 25 ar.icles wer. consider.d per.inent and 17 wer. chosen for.the pr.sent systematic r.view. Eleven monocentr.c ser.es, 1 multicentr.c ser.es, 1 casecontr.l study, 1 population-based study and 3 case r.por. wer. included. A total of 2881 patients wer. globally analyzed as study gr.up, and the incidence of pancr.atic cancer.and/or.extr.pancr.atic malignancies r.nged fr.m 5% to 52%, with a mean of 28.71%.When a contr.l gr.up was analyzed(6 paper.), the same incidence was as low as 9.4%.CONCLUSION: The available Liter.tur. is unanimous in claiming IPMNs to be str.ngly associated with pancr.atic and extr.pancr.atic malignancies. The consequences in IPMNs management ar. her.in discussed.

关键词： Intr.ductal papillar. mucinous neoplasm Pancr.as Diagnosis Follow-up Tumor. Computedtomogr.phy scan 18FDG-PET

COMPAr.SON OF NON PENETr.TING FILTr.TION SUr.Er. FOr.OPEN ANGLE GLAUCOMA WITH NON ABSOr.ABLE IM-PLANT (T FLUX) VEr.US Tr.BECULEC-TOMY: A MULTICENTr.C STUDY

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国际眼科杂志 2003年第1期3卷 55-55页

作者： M.Dal Vecchio B.Br.gliatti T.r.lle F.M.Gr.gnolo L.Bauchier. G.Vadala G.Car.mello M.Br.ni F.molfino E.Gr.mmo Eye Clinic Univer.ity of Tur.n Eye Clinic University of TurinEye Clinic University of TurinEye Clinic University of TurinEye Departmentt of Civil Hos-pitalEye Departmentt of Civil Hos-pitalEve Department of Santa Croce HospitalEve Department of Santa Croce HospitalEve Department of Santa Croce HospitalOcular Traumathology Department of Ophthalmic Hospital Italy

Pur.ose: To compar. the efficacy and safety of deep scler.ctomy with no absor.able implant (T flux) vs tr.beculectomy in POAG eyes. Methods: 23 eyes of 19 patients with medically uncontr.lled open angle glaucoma under.ent to deep scler.ctomy with non absor.able implant (T flux). The postoper.tive IOP values and the fr.quency of complications wer. matched with those of a gr.up of 34 eyes of 34 POAG patients oper.ted with tr.beculectomy. The examinations wer. per.or.ed befor. sur.er. and post-

关键词：开角型青光眼非穿透性滤过术非可吸收埋植物小梁切除术比较研究

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