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Serum ferritin in neonatal cholestasis: A specific and active molecule or a non-specific bystander marker?

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Hepatobiliary & Pancreatic Diseases International 2019年第2期18卷 173-180页

作者： Behairy el-Sayed Behairy Hatem abd-Alsattar Konswa Hanaa Talaat Ahmed Dina Shehata el-Azab Nermin mohamed Adawy Ahmad mohamed Sira Department of Pediatric Hepatology Gastroenterology and Nutrition National Liver Institute Menofiya University Department of Pathology National Liver Institute Menofiya University

Background: Serum ferritin(SF) and consequently hepatic iron have long been considered important in liver fibrosis progression. They have been studied in different liver diseases with no previous reports in neonatal cholestasis(NC). This study aimed to measure SF in different etiologies of NC and investigate its relation to hepatic iron and fibrosis. Methods: SF was measured in 75 infants, including 50 with NC and 25 with sepsis. SF was compared between these two groups. Biochemical parameters, hepatic iron grades, and liver fibrosis and other histopathological characteristics and correlated with SF were assessed in NC group. Finally, a comparison between intrahepatic cholestasis and obstructive etiology was performed. Results: SF was elevated in NC(1598 ± 2405 ng/mL) with no significant difference from those with sepsis( P = 0.445). NC and sepsis constituted augmenting factors leading to more elevation of SF(2589 ± 3511 ng/mL). SF was significantly correlated with hepatic iron grades( r = 0.536, P ell transformation( P = 0.009) and hepatocyte swelling( P = 0.023) than those with obstructive etiology(672 ± 566 ng/mL) and their prevalent pathological findings of ductular proliferation( P = 0.003) and bile plugs( P = 0.002). SF was unrelated to the grade of liver fibrosis( P = 0.058). Conclusions: SF is non-specifically elevated in NC, with positive correlation to hepatic iron grades. SF ≥ 803.5 ng/mL can predict higher grades( ≥ grade 3) of hepatic iron. However, an active role of increased SF and hepatic iron in disease progression remains questionable.

关键词： Biliary atresia Liver fibrosis Hepatic iron grade Intrahepatic cholestasis Iron

Facies Analysis and Biostratigraphy of the Miocene Sequence,Cairo-Suez District,Egypt

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Journal of Earth Science 2017年第1期28卷 1-8页

作者： abdelbaset el-Sorogy mohamed abd-elmoneim Ahmed Mowafi Khaled Al-Kahtany Hisham Gahlan Department of Geology and Geophysics College of Science King Saud University Riyadh 11451 Saudi Arabia Geology Department Faculty of Science Zagazig University Zagazig 44519 Egypt

Miocene siliciclastic-carbonate deposits are widely exposed in Cairo-Suez District, Egypt. These deposits are underlain and overlain by continental sediments of Oligocene and post Miocene, respectively. Three stratigraphic sections were investigated at Gabals Geneife, Homeira and Gharra. Lithostrtigraphically, the Miocene sequence could be differentiated into two main rock units representing shallow deposits with relatively intermittent deep marine incursions. These are from base to top, Gharra Formation and Genefe Formation. Detailed macrofossils investigations led to the recognition of four macrofossil zones, namely Alectryonella plicatula-Crassostrea frondosa Range Zone, Echinolampas amplus-Scutella ammonis Range Zone, Chlamys（Macrochlamys） sardoa-Chlamys（Argopecten） submalvinae Range Zone, and Chlamys gentoni-Pecten（Oppenheimopecten） benedictus-Pecten（P.） ziziniae Assemblage Zone. Microfacies analysis and identified taxa indicated that the Miocene sequence was deposited in transgressive-regressive cycles ranged from near shore, warm shallow inner to middle shelf marine environments with storm influence during the accumulation of the oyster banks.

关键词： facies analysis biostratigraphy Miocene Cairo-Suez District Egypt.

纯铝等径角挤压及等径角挤压和直接挤压结合的塑性变形3D有限元模拟和实验验证（英文）

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Transactions of Nonferrous Metals Society of China 2017年第6期27卷 1338-1352页

作者： mohamed Ibrahim abd el AAL Mechanical engineering Department College of Engineering Prince Sattam Bin Abdulaziz UniversityWadi Addawasir Kingdom of Saudi Arabia Mechanical Design & Production Department Faculty of Engineering Zagazig University Zagazig Egypt

对纯铝进行等径角挤压、等径角挤压结合不同挤压比直接挤压及直接挤压,并采用刚-粘塑性3D有限元模拟进行分析。利用3D有限元模拟研究不同成形过程变形Al-1080的载荷-位移行为、塑性变形特征和有效塑性应变均匀性。用显微组织观察、显微... 详细信息

对纯铝进行等径角挤压、等径角挤压结合不同挤压比直接挤压及直接挤压,并采用刚-粘塑性3D有限元模拟进行分析。利用3D有限元模拟研究不同成形过程变形Al-1080的载荷-位移行为、塑性变形特征和有效塑性应变均匀性。用显微组织观察、显微硬度分布图、有效塑性应变和显微硬度值验证模拟结果。结果表明:模拟结果与实验结果一致;模拟载荷-位移曲线和最大载荷与实验结果接近;显微硬度分布图符合有效塑性应变等高线,证实了3D有限元模拟结果。等径角挤压工件的变形均匀性程度比其他变形过程的高。根据平均有效塑性应变计算了显微硬度值。预测显微硬度值与实验结果吻合。横向和纵向显微组织观察验证了不同成形过程中3D有限元模拟有效塑性应变和显微硬度分布结果。

关键词：等径角挤压挤压有限元法显微硬度变形均匀性显微组织

Training program for caregivers to prevent pressure ulcers among elderly residents at geriatric homes

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Frontiers of Nursing 2021年第3期8卷 249-259页

作者： Donia Atef Ibrahiem Mona mohamed abd el-Maksoud Community Health Nursing Faculty of NursingHelwan UniversityCairo 11571Egypt

Objectives:Pressure ulcer(PU)is one of the most common problem among the bedridden elderly and has significantly more burden on elderly and *** study is aimed to evaluate the effects of the training program for caregivers to prevent PUs among elderly residents at geriatric ***:A quasi-experimental design was used to carry out the current study.A purposive sample comprised of all formal(39 nurses)or informal caregivers(39)and all immobilized elderly residents(35)who are found in all geriatric centers in Helwan district.A structured questionnaire was used to assess caregivers’socio-demographic characteristics,knowledge,attitude,and observational checklists for their practice for prevention of PU at pre-and posttest and during ***:After the training program,there were improvements in the level of knowledge,practice,and positive attitude of caregivers about PU prevention with a statistically significant difference between pre-,post-,and follow-up training programs(Pelderly caregivers’attitudes as well as practice for prevention could be important in reducing the burden of PU among the ***,conducting a training program for caregivers at different geriatric homes about caring skills for elders can prevent PU,and using spontaneous reposition is very effective to prevent PUs.

关键词： caregivers elderly residents geriatric homes pressure ulcers training program

Corrosion inhibition of carbon steel in hydrochloric acid by cationic arylthiophenes as new eco-friendly inhibitors: Experimental and quantum chemical study

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Chinese Journal of Chemical Engineering 2021年第12期34卷 197-217页

作者： abd el-Aziz S.Fouda mohamed A.Ismail abdulraqeb A.Al-Khamri Ashraf S.Abousalem Department of Chemistry Faculty of ScienceEl-Mansoura UniversityEl-Mansoura 35516Egypt Department of Chemistry Faculty of EducationArts and SciencesUniversity of Saba RegionMaribYemen Quality Control Laboratory Operations DepartmentJotunEgypt

This study describes the adsorption behavior of three arylthiophene derivatives namely:2-(4-amidino-3-fluorophenyl)-5-[4-methoxy phenyl] thiophene dihydrochloride salt(MA-1217),2-(4-amidinophenyl)-5-[4-chlorophenyll thiophene dihydrochloride salt(MA-1316) and 2-(4-amidino-3-fluorophenyl)-5-[4-ch lorophenyllthiophene dihydrochloride salt(MA-1312) at C-steel in 1.0 mol·L^(-1) HCl interface using experimental and theoretical *** and mass loss measurements showed that the inhibition efficiency(IE) of the arylthiophene derivatives increases with increasing concentrations and exhibited maximum efficiency 89% at 21×10^(-6) mol·L^(-1)(MA-1217) by mass loss *** investigated arylthiophene derivatives obey the Langmuir adsorption *** polarization studies the arylthiophene derivatives act as mixed-type *** analysis were carried out and *** mode of orientation and adsorption of inhibitor molecules on C-steel surface was studied using molecular dynamics(MD) *** chemical parameters as well as the radial distribution function indices and binding energies confirm the experimental results.

关键词： Carbon steel Corrosion inhibition Adsorption Arylthiophene derivatives Polarization electrochemical frequency modulation

Determination of a novel ACE inhibitor in the presence of alkaline and oxidative degradation products using smart spectrophotometric and chemometric methods

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Journal of Pharmaceutical Analysis 2014年第2期4卷 132-143页

作者： Maha abdel-Monem Hegazy Maya Shaaban Eissa Osama Ibrahim abd el-Sattar mohamed mohamed abd el-Kawy Analytical Chemistry Department Faculty of PharmacyCairo UniversityCairoEgypt Analytical Chemistry Department Faculty of PharmacyEgyptian Russian UniversityCairoEgypt National Organization of Drug Control and Research GizaEgypt

Simple, accurate, sensitive and validated UV spectrophotometric and chemometric methods were developed for the determination of imidapril hydrochloride （IMD） in the presence of both its alkaline （AKN） and oxidative （OXI） degradation products and in its pharmaceutical formulation. Method A is the fourth derivative spectra （D4） which allows the determination of IMD in the presence of both AKN and OXD, in pure form and in tablets by measuring the peak amplitude at 243.0 nm. Methods B, C and D, manipulating ratio spectra, were also developed. Method B is the double divisor-ratio difference spectrophotometric one （DD-RD） by computing the difference between the amplitudes of IMD ratio spectra at 232 and 256.3 nm. Method C is the double divisor-first derivative of ratio spectra method （DD-DR1） at 243.2 nm, while method D is the mean centering of ratio spectra （MCR） at 288.0 nm. Methods A, B, C and D could successfully determine IMD in a concentration range of 4.0-32.0 mg/mL. Methods E and F are principal component regression （PCR） and partial least-squares （PLS）, respectively, for the simultaneous determination of IMD in the presence of both AKN and OXI, in pure form and in its tablets. The developed methods have the advantage of simultaneous determination of the cited components without any pre-treatment. The accuracy, precision and linearity ranges of the developed methods were determined. The results obtained were statistically compared with those of a reported HPLC method, and there was no significant difference between the proposed methods and the reported method regarding both accuracy and precision.

关键词： Double divisor-ratio difference Double divisor-ratio derivative Mean centering of ratio spectra Chemometry Imidapril hydrochloride

Recent Advances of Chimp Optimization Algorithm:Variants and Applications

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Journal of Bionic Engineering 2023年第6期20卷 2840-2862页

作者： Mohammad Sh.Daoud Mohammad Shehab Laith Abualigah Mohammad Alshinwan mohamed abd elaziz Mohd Khaled Yousef Shambour Diego Oliva Mohammad AAlia Raed Abu Zitar College of Engineering Al Ain University112612Abu DhabiUnited Arab Emirates College of Computer Sciences and Informatics Amman Arab UniversityAmman11953Jordan Computer Science Department Prince Hussein Bin Abdullah Faculty for Information TechnologyAl Al-Bayt UniversityMafraq25113Jordan Hourani Center for Applied Scientific Research Al-Ahliyya Amman UniversityAmman19328Jordan MEU Research Unit Middle East UniversityAmman11831Jordan Applied Science Research Center Applied Science Private UniversityAmman11931Jordan School of Computer Sciences Universiti Sains Malaysia11800Pulau PinangMalaysia Faculty of Information Technology Applied Science Private UniversityAmman 11931Jordan Department of Mathematics Faculty of ScienceZagazig UniversityZagazig 7120001Egypt The Custodian of the Two Holy Mosques Institute for Haj and Umrah Research Umm Al-Qura UniversityMakkah 24382Saudi Arabia Depto.de Innovacio'n Basada en la Informacio'n y el Conocimiento Universidad de GuadalajaraCUCEI45129 GuadalajaraMexico Cyber Security Department Faculty of Science and Information TechnologyAl Zaytoonah University of JordanAmman 11733Jordan Sorbonne Center of Artificial Intelligence Sorbonne University-Abu Dhabi38044 Abu DhabiUnited Arab Emirates School of Engineering and Technology Sunway University Malaysia27500Petaling JayaMalaysia

Chimp Optimization Algorithm(ChOA)is one of the recent metaheuristics swarm intelligence *** has been widely tailored for a wide variety of optimization problems due to its impressive characteristics over other swarm intelligence methods:it has very few parameters,and no derivation information is required in the initial ***,it is simple,easy to use,flexible,scalable,and has a special capability to strike the right balance between exploration and exploitation during the search which leads to favorable ***,the ChOA has recently gained a very big research interest with tremendous audiences from several domains in a very short ***,in this review paper,several research publications using ChOA have been overviewed and ***,introductory information about ChOA is provided which illustrates the natural foundation context and its related optimization conceptual *** main operations of ChOA are procedurally discussed,and the theoretical foundation is ***,the recent versions of ChOA are discussed in detail which are categorized into modified,hybridized,and paralleled *** main applications of ChOA are also thoroughly *** applications belong to the domains of economics,image processing,engineering,neural network,power and energy,networks,*** of ChOA is also *** review paper will be helpful for the researchers and practitioners of ChOA belonging to a wide range of audiences from the domains of optimization,engineering,medical,data mining,and *** well,it is wealthy in research on health,environment,and public ***,it will aid those who are interested by providing them with potential future research.

关键词： Artificial intelligence Nature-inspired optimization algorithms Chimp optimization algorithm Optimization problems

Physiological Role of Humic Acid and Nicotinamide on Improving Plant Growth, Yield, and Mineral Nutrient of Wheat (<i>Triticum durum</i>) Grown under Newly Reclaimed Sandy Soil

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Agricultural Sciences 2014年第8期5卷 687-700页

作者： Hala Safwat mohamed el-Bassiouny Bakry Ahmed Bakry Amany abd el-Monem Attia Maha mohamed abd allah Agronomy Department Agriculture and Biology Division National Research Center Cairo Egypt Botany Department Agriculture and Biology Division National Research Center Cairo Egypt

Humic acid is not a fertilizer as it does not directly provide nutrients to plants, but is a compliment to fertilizer. Nicotinamide (Vitamin pp) is a stress-associated compound that can induce and regulate secondary metabolic accumulation and/or the manifestation of defense metabolism in plants. A field experiment was conducted at the experimental station of National Research center at el-Nubaria region, Egypt, to study the role of foliar application of humic acid (as soil conditioner 13 cm/l) and/or priming grains in nicotinamide (vitamin pp 5 mg/l) in saving irrigation water, decreasing fertilizer dose of NPK and at the same time increasing durum wheat (Triticum durum) cultivars’ (Beni Sweif-1 and Beni Sweif-3) productivity grown under newly reclaimed sandy soil exposed to drought for three weeks continuously. The results showed that plant treated with humic acid or nicotinamide increased significantly all morphological criteria (plant height, leaves number, fresh and dry weights of shoots), metabolism (photosynthetic pigment, total soluble sugar, total carbohydrates, total amino acids and proline), mineral contents (N, P, K, Ca and Mg) and yield (grain, straw and biology) of both cultivars amended with either recommended or half recommended doses of NPK. Foliar application of humic acid to plant priming in Vitamin pp induced significant increases in all studied parameters (morphology, chemical and yield) of plants amended with recommended or half recommended doses of NPK as compared with control plants. The maximum yields of grain, straw and biology of both cultivars were obtained in response to triple treatment (humic acid + nicotinamide + recommended dose of NPK) or (humic acid + nicotinamide + half recommended dose of NPK) respectively.

关键词： Humic Acid Metabolism Mineral Ions Nicotinamide Wheat

Functional evaluation of the filtering bleb by ultrasound biomicroscopy after trabeculectomy with mitomycin C

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International Journal of Ophthalmology(English edition) 2018年第2期11卷 245-250页

作者： Ali Abbas el Salhy Rabab mohamed elseht Ahmed Fekry AI Maria Saied mohamed abd el-wahab Shalaby Tarek Ragaee Hossein Kafr el Sheikh Ophthalmology Hospital Health MinistryKafr EL Sheikh 33511Egypt Department of Ophthalmology Tanta UniversityTanta 31511Egypt

AIM： To study the role of ultrasound biomicroscopy（UBM） in the assessment of the bleb function after trabeculectomy with mitomycin C（MMC）. METHODS： This was a cross-sectional study including all cases had undergone trabeculectomy with MMC 0.2 mg/mL for 3 min. Participants were recruited from the follow-up cases at Department of Ophthalmology, Tanta University in the period from August 2015 to August 2016. Full history taking and ophthalmological examination were performed. Intraocular pressure（IOP） was measured using Goldmann applanation tonometry and the history of prescribed postoperative antiglaucoma medications was recorded. Accordingly, the trabeculectomy blebs were divided clinically into successful blebs when the IOP post-operative was ≤18 mmHg without medications. Scanning examination of the filtering bleb using UBM examination was performed at the period from 2 to 36 mo after trabeculectomy（13.6±9.7 m o）. RESULTS： This study included 33 trabeculectomy filtering blebs of 25 patients（9 males and 16 females）. The mean age of patients was 53.2±14.2 y（range 25-71y）. We had 20 eyes with complete success, 9 eyes with qualified success, and 4 eyes with failure after trabeculectomy with MMC. The blebs were classified into successful blebs（IOP ≤18 mmHg without antiglaucoma medications）, others were classified into qualified successful and failed blebs. There was a significant correlation between certain UBM findings（intra-bleb reflectivity, draining sub-scleral tract, bleb height, and intrableb fluid cysts） and cases with different grades of clinical functional success（P〈0.01）.CONCLUSION： UBM is an objective tool in the functional assessment of the post-trabeculectomy filtering bleb through a significant correlation between certain UBM parameters and the different grades of clinical functional success.

关键词： filtering bleb bleb reflectivity sub-scleral tract ultrasound biomicroscopy sclerotomy site