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Journal of Partial Differential Equations 2023年第4期36卷 381-393页

作者： AHMAD Manzoor mishra rajshree JAIN Renu School of Mathematics and Allied Sciences jiwaji UniversityGwalior-474011India Govt.Model Science College Gwalior-474011India

.Option pricing is a major problem in quantitative *** Black-Scholes model proves to be an effective model for the pricing of *** this paper a com-putational method known as the modified differential transform method has been em-ployed to obtain the series solution of Black-Scholes equation with boundary condi-tions for European call and put options paying continuous *** proposed method does not need discretization to find out the solution and thus the computa-tional work is reduced *** results are plotted graphically to establish the accuracy and efficacy of the proposed method.

关键词： European option pricing Black-Scholes equation call option put option modified differential transform method

Geochemistry and petrogenesis of magnesian high-K granitoids from Bundelkhand Craton,Central India:New insights into crustal evolution

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Acta Geochimica 2025年第1期44卷 36-58页

作者： Shailendra K.Prajapati Meraj Alam Parashar mishra Hemant Kumar Geological Survey of India Northern RegionLucknowUP 226024India Department of Geology Indira Gandhi National Tribal UniversityAmarkantakMP 484887India

Background The Bundelkhand Craton is significant for preserving the multiphase granitoids magmatism from Paleoarchean to Neoarchean *** consists of a variety of granite rocks,including TTGs,sanukitoids,and high-K *** study presents geochemical characteristics of high-silica(68.97 wt.%–73.99 wt.%),low-silica(58.73wt.%–69.94 wt.%),and high K_(2)O(2.77 wt.%–6.16 wt.%)contents of *** The data on Bundelkhand Craton’s granitic magmatism and geodynamics is not sufficiently *** data from this study will be used to further understand the origin,source,and petrogenesis of granitoid rocks and their implications for the evolution of *** Twenty-one samples were collected and analyzed for major,trace,and REE *** elements were measured using X-ray fluorescence spectrometry(XRF),and trace and REE elements were analyzed by *** procedures from the Geological Survey of India were *** The geochemical analysis presents high-silica(68.97-73.99 wt.%),low-silica(58.73-69.94 wt.%),and high K_(2)O(2.77-6.16 wt.%)contents in granitoids,classified as *** rocks are calcic to calcalkalic,magnesian,and range from peraluminous to metaluminous *** patterns showed strong LREE enrichment relative to HREEs,with prominent negative Eu anomalies corresponding to earlier plagioclase ***-element patterns revealed negative anomalies in Nb,Sr,P,and Ti and positive anomalies in *** The geochemical signatures attributed to the post-collisional magma generation and continental crustal *** studied rocks show A-type and A2-type lineage,suggesting they originated from the melting of continental crust during transitional/post-collisional tectonic *** formation of hybrid granitoids in the Bundelkhand Craton is connected to the fractionation of hybrid magmas in shallow-seated magma chambers during these tectonic processes.

关键词： Geochemistry Petrogenesis A-type granites Crustal evolution Bundelkhand craton

E3 Ligases and COVID-19:Insights into Viral Control andTherapeutic Potential

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BIOCELL 2025年第1期49卷 127-147页

作者： Mukul mishra Deeba Khan Sehbanul Islam Department of Cancer Biology Abramson Family Cancer Research InstitutePerelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA 19104USA Department of Pathology Jawaharlal Nehru Medical CollegeAligarh Muslim UniversityAligarh202002Uttar PradeshIndia

The COVID-19 pandemic,caused by the newly emerged coronavirus SARS-CoV-2,has resulted in unprecedented global health challenges,including millions of infections and *** the direct effects of the virus are critical,the interplay between SARS-CoV-2 and cellular host factors significantly impacts the replication cycle of the virus and the clinical severity of *** review provides a comprehensive analysis of hostpathogen interactions,focusing on the functional roles and regulatory mechanisms of SARS-CoV-2 viral *** systematically review the literature to detail how SARS-CoV-2 engages with host cellular machinery,with a specific emphasis on their modulation by E3 ubiquitin *** dissecting these intricate interactions and the impact of E3 ligases on SARS-CoV-2 infection,we aimto uncover novel therapeutic opportunities and strategies to effectively combat COVID-19.

关键词： SARS-CoV-2 COVID-19 viral proteins host-pathogen interaction E3 ubiquitin ligases ubiquitination targeted protein degradation

Practice patterns among ophthalmic surgeons in treating concomitant oculoplastic conditions in preoperative period:A questionnaire-based study

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World Journal of Clinical Cases 2025年第1期13卷 29-37页

作者： Bijnya Birajita Panda Chitaranjan mishra Bhagabat Nayak Avik Kumar Roy Logesh Balakrishnan Priyadarshini mishra Department of Ophthalmology All India Institute of Medical SciencesBhubaneswar 751019OdishaIndia Department of Vitreo-Retina Trilochan NetralayaSambalpur 768004India Department of Glaucoma Services LV Prasad Eye InstituteBhubaneswar 751013India Department of Statistics Apollo HospitalsChennai 823104India

BACKGROUND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic *** oculoplastic conditions,like nasolacrimal duct obstruction,have been extensively studied,whereas others,like eyelid malposition and thyroid eye disease,have received minimal or no *** To investigate the current practice patterns among ophthalmologists while treating concomitant oculoplastic conditions before any subspecialty ophthalmic *** A cross-sectional survey was disseminated among ophthalmologists all over *** survey included questions related to pre-operative evaluation,anaesthetic and surgical techniques preferred,post-operative care,the use of adjunctive therapies,and patient follow-up *** A total of 180 ophthalmologists responded to the *** practitioners(89%)felt that the ROPLAS test was sufficient during pre-operative evaluation before any subspecialty surgery was *** most common surgical techniques employed were lacrimal drainage procedures(Dacryocystorhinostomy)(63.3%),eyelid malposition repair(36.9%),and ptosis repair(58.7%).Post-operatively,47.7%of respondents emphasized that at least a 4-week gap should be maintained after lacrimal drainage procedures and eyelid ***-seven percent of ophthalmologists felt that topical anaesthetic procedures should be preferred while performing ocular surgeries in thyroid eye disease *** Approximately 50%of ophthalmologists handle prevalent oculoplastic issues themselves,seeking the expertise of an oculoplastic surgeon under particular *** ophthalmologists still favor using ROPLAS as a preliminary screening method before proceeding with cataract *** conditions and thyroid eye disease are not as commonly addressed before subspecialty procedures compared to issues like nasolacrimal duct obstruction and periocular infections.

关键词： Oculoplasty Ophthalmic plastic surgery Nasolacrimal duct obstruction Practice patterns Survey

A Novel Proactive AI-Based Agents Framework for an IoE-Based Smart Things Monitoring System with Applications for Smart Vehicles

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Computers, Materials & Continua 2025年第2期82卷 1839-1855页

作者： Meng-Hua Yen Nilamadhab mishra Win-Jet Luo Chu-En Lin Department of Electronic Engineering National Chin-Yi University of TechnologyTaichung411030Taiwan School of Computing Science&Engineering VIT Bhopal UniversityBhopal466114India Department of Refrigeration Air-Conditioning and Energy EngineeringNational Chin-Yi University of TechnologyTaichung411030Taiwan

The Internet of Everything(IoE)coupled with Proactive Artificial Intelligence(AI)-Based Learning Agents(PLAs)through a cloud processing system is an idea that connects all computing resources to the Internet,making it possible for these devices to communicate with one *** featured in the IoE include embedding,networking,and sensing *** achieve the intended results of the IoE and ease life for everyone involved,sensing devices and monitoring systems are linked *** IoE is used in several contexts,including intelligent cars’protection,navigation,security,and fuel *** Smart Things Monitoring System(STMS)framework,which has been proposed for early occurrence identification and theft prevention,is discussed in this *** STMS uses technologies based on the IoE and PLAs to continuously and remotely observe,control,and monitor *** STMS is familiar with the platform used by the global positioning system;as a result,the STMS can maintain a real-time record of current vehicle *** information is utilized to locate the vehicle in an accident or *** findings of the STMS system are promising for precisely identifying crashes,evaluating incident severity,and locating vehicles after collisions have ***,we formulate an ad hoc STMS network communication scenario to evaluate the efficacy of data communication by utilizing various network parameters,such as round-trip time(RTT),data packet transmission,data packet reception,and *** our experimentation,we obtained an improved communication efficiency for STMS across multiple PLAs compared to the standard greedy routing and traditional AODV *** framework facilitates adaptable solutions with communication competence by deploying Proactive PLAs in a cloud-connected smart vehicular environment.

关键词： Artificial intelligence(AI) proactive AI-based learning agents(PLA) internet of everything(IoE) smart things monitoring system(STMS) cloud processing system driving monitoring assistance system(MAS) smart vehicles

Anticonvulsant potential of rosuvastatin in combination with carbamazepine and valproate in animal models of epilepsy

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World Journal of Methodology 2025年第2期15卷 137-144页

作者： Vandana Tayal Akash Mandal Ijasul Haque M Akhilesh mishra Bhupinder S Kalra Vandana Roy Department of Pharmacology Maulana Azad Medical CollegeNew Delhi 110002India Department of Pharmacology MES Medical CollegePerintalmanna 679338KeralaIndia Department of Central Animal Facility Maulana Azad Medical CollegeNew Delhi 110002India

BACKGROUND Epilepsy impacts millions of people,with many not responding to existing *** evidence links neuroinflammatory processes to *** exhibit anti-inflammatory and neuroprotective properties,potentially offering antiepileptic *** To evaluate the anticonvulsant effects of rosuvastatin in animal models of *** Ninety-six albino mice were divided into 16 *** the maximal electroshock seizure(MES)model,eight groups received intraperitoneal vehicle,carbama-zepine,rosuvastatin,or a *** measured included seizure protection[tonic hind limb extension(THLE)],duration of THLE,seizure duration,and *** the pentylenetetrazol(PTZ)model,eight groups were pretreated with vehicle,valproate,rosuvastatin,or a combination,with outcomes measured as seizure latency,seizure duration,and *** In the MES model,rosuvastatin exhibited protection against THLE in a small percentage of *** shortens the duration of THLE in a dose-dependent ***,none of these were statistically significant com-pared to the control *** combination of rosuvastatin 10 mg/kg with carbamazepine 4 mg/kg resulted in a significant reduction in seizure duration compared to the control group,better than carbamazepine alone at 4 mg/kg and 6 mg/*** the PTZ model,rosuvastatin alone showed no significant effects on latency,duration of seizure,or ***,rosuvastatin 10 mg/kg combined with valproate 100 mg/kg significantly delayed the onset of seizures,seizure duration and mortality percentage,better than valproate alone at 100 mg/*** Rosuvastatin enhanced the anticonvulsant effects of carbamazepine and *** studies are required to explore the antiepileptic potential of rosuvastatin at various doses,durations,dosage forms,routes and models.

关键词： Antiepileptic Anticonvulsant Statins Rosuvastatin Maximal electroshock seizure Pentylenetetrazol

Protocolized approach saves the limb in peripheral arterial injury:A decade experience

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Chinese Journal of Traumatology 2025年第1期28卷 62-68页

作者： Pratyusha Priyadarshini Supreet Kaur Komal Gupta Abhinav Kumar Junaid Alam Dinesh Bagaria Narender Choudhary Amit Gupta Sushma Sagar Biplab mishra Subodh Kumar Division of Trauma Surgery&Critical Care Jai Prakash Narayan Apex Trauma CentreAll India Institute of Medical SciencesNew DelhiIndia

Purpose:Outcomes of peripheral arterial injury(PAI)depend on various factors,such as warm ischemia time and concomitant *** prehospital care may lead to delayed presentation,and a lack of dedicated trauma system may lead to poorer ***,there are few reports of these *** study aims to review our experience of PAI management for more than a decade,and identify the predictors of limb loss in these ***:This is a retrospective analysis of prospectively maintained database of trauma admissions at a level I trauma center from January 2008 to December *** with acute upper limb arterial injuries or lower limb arterial injuries at or above the level of popliteal artery were *** of limb loss with ischemia time,mechanism of injury,and concomitant injuries was studied using multiple logistic *** analysis was performed using STATA version 15.0(Stata Corp LLC,Texas).Results:Out of 716 patients with PAI,the majority(91.9%)were young *** trauma was the most common mechanism of *** ischemia time was 4 h(interquartile range 2-7 h).Brachial artery(28.5%)was the most common injured vessel followed by popliteal artery(17.5%)and femoral artery(17.3%).Limb salvage rate was 78%.Out of them,158(22.1%)patients needed amputation,and 53(7.4%)had undergone primary *** majority(88.6%)of patients who required primary or secondary amputations had blunt *** multivariate analysis,blunt trauma,ischemia time more than 6 h and concomitant venous,skeletal,and soft tissue injuries were associated with higher odds of ***:Over all limb salvage rates was 77.9%in our *** mechanism of injury and associated skeletal and soft tissue injury,ischemia time more than 6 h portend a poor *** prevention,robust prehospital care,and rapid referral to specialized trauma center are few efficient measures,which can decrease the morbidity associated with vascu

关键词： Vascular trauma Extremity vascular injury Amputation Vascular injury repair Peripheral arterial injury

Performance of Corrosion-Resistant Alloys in Concentrated Acids

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Acta Metallurgica Sinica(English Letters) 2017年第4期30卷 306-318页

作者： Ajit mishra Research and Technology Haynes International 1020 ParkAve Kokomo IN 46902 USA

Nickel alloys containing optimum amounts of chromium （Cr）, molybdenum （Mo） and tungsten （W） are widely used in the chemical processing industries due to their tolerance to both oxidizing and reducing conditions. Unlike stainless steel （SS）, Ni-Cr-Mo （W） alloys exhibit remarkably high uniform corrosion resistance in major concentrated acids, like hydrochloric acid （HC1） and sulfuric acid （H2SO4）. A higher uniform corrosion resistance of Ni-Cr-Mo （W） alloys, compared to other alloys, in concentrated acids can be attributed to the formation of protective oxide film of Mo and W in reducing acids, and Cr oxide film in oxidizing solutions. The localized corrosion resistance of Ni-Cr-Mo （W） alloys, containing high amount Cr as well as Mo （or Mo ＋ W）, is also significantly higher than that of other commercially available alloys. The present study investigates the role of alloying elements, in nickel alloys, to uniform corrosion resistance in concentrated acids （HC1, HC1 ＋ oxidizing impurities and H2SO4） and localized corrosion performance in chloride-rich environments using ASTM G-48 test methodology. The corrosion tests were conducted on various alloys, and the results were analyzed using weight loss technique and electrochemical techniques, in conjunction with surface char- acterization tools.

关键词： Nickel-chromium-molybdenum-tungsten Corrosion-resistant alloys Reducing acid Oxidants Localized corrosion Surface characterization

Corrosion Study of Base Material and Welds of a Ni-Cr-Mo-W Alloy

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Acta Metallurgica Sinica(English Letters) 2017年第4期30卷 326-332页

作者： Ajit mishra Haynes International Inc. 1020 West Park AvenueKokomo IN 46904 USA

Alloys containing chromium （Cr） and molybdenum （Mo）, as the major alloying elements, are widely used in various industries where the material experiences corrosive environments. Chromium （Cr）, when added in an optimum amount, forms a Cr203 passive film which protects the underlying metal in aggressive solutions. Molybdenum （Mo） forms its oxides in the low pH solutions, thus, enhances the uniform corrosion resistance of an alloy in reducing acids and assists in inhibition to localized corrosion. Minor alloying elements, like tungsten （W） and copper （Cu）, also improve the overall corrosion resistance of an alloy in specific solutions. In the present study, corrosion resistance behavior of commercial iron- based alloys （316L SS, 254 SMO and 20Cb3） and nickel-based alloys （Mone1400, Alloy 625 and C-276） was studied in the acidic solutions. While the corrosion behavior of wrought alloys has been widely studied, there is little to no information on the corrosion performance of their welds, typically being the weak regions for corrosion initiation and propagation. Therefore, an attempt was undertaken to investigate the uniform and localized corrosion performance of base metal, simulated heat-affected zone and all-weld-metal samples of a Ni-Cr-Mo-W alloy, C-276. The study was conducted in aggressive acidic solutions. Various corrosion and surface analytical techniques were utilized to analyze the results.

关键词： Iron-chromium-molybdenum Nickel-chromium-molybdenum-tungsten All-weld-metal Heat-affected-zone Acids Acidified ferric chloride Potentiodynamic Scanning electronmicroscopy (SEM)

Geochemistry of Late Archaean shaly BIF formed by oxic exogenic processes: an example from Ramagiri schist belt,Dharwar Craton, India

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Chinese Journal Of Geochemistry 2015年第3期34卷 362-378页

作者： Meenal mishra School of Sciences Indira Gandhi National Open University

The central block of the auriferous Ramagiri schist belt, in the Eastern Dharwar Craton, India consists of bimodal volcanics(mafic-felsic), shaly BIF and metasedimentary rocks. Geochemical studies of the associated shaly BIF have indicated the enrichment of the major and trace elements such as Si O2, Al2O3, Ti O2, K2 O, Mg O, Fe2O3(T),Zr, Y, Cr, Ni, alkali and alkaline earth elements indicates that the clastic component of the shaly BIF had their contribution from the contemporaneous bimodal *** concave chondrite normalized REE patterns share ubiquitously anomalous positive cerium anomaly, absence of positive europium anomaly and the overall HREE enrichment. The REE patterns resemble those from the modern day sea water, except for positive Ce anomaly. The data suggests that arc related bimodal volcanism had been the plausible source of Fe, silica, REE and other trace elements. The coherent behaviour of Fe, Ti, Mn and P with the REEs indicates that they got incorporated from Fe–Ti–Mn bearing primary minerals and secondary products like clays. The variability of REE patterns in the BIF formation samples probably results from the differences in scavenging efficiency. The BIF bears signatures of mixing of the contemporaneous clastic and chemical processes, as well as the changes accompanying diagenesis and *** precipitation of Fe did not stop during the sedimentation in an island arc related tectonic setting. The BIF strongly lacks the signatures from hydrothermal input. The presence of positive cerium anomalies and the absence of positive europium anomalies in the shaly banded ironformations imply that iron oxidation during BIF deposition took place in shallow waters rather than at depth, at oxicanoxic boundary.

关键词：地球化学二氧化硅克拉通晚太古代岩带印度力作用双峰式火山岩