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Bioinspired Fluorescent Polymers: Synthesis, Processing, and Applications

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Chinese Journal of Chemistry 2023年第4期41卷 458-468页

作者： Hongxue Xu Wei Zhang mingfeng wang School of Science and Engineering The Chinese University of Hong KongShenzhenGuangdong518172 China

The discovery of fluorescent proteins has inspired a lot of interest to develop synthetic polymers with similar structures and *** this review article,we first give a brief introduction for the discovery,the structural characteristics and optical properties of fluorescent proteins,using green fluorescent protein(GFP)as an *** the body part of article,we summarize recent advances in molecular design,synthesis and processing of bioinspired fluorescent polymers with unique optical properties such as high fluorescence quantum yield and robust *** major approaches highlighted here include the recombination of organic chromophores and proteins,and synthesis of the bioinspired polymers containing a single fluorophore in each polymer *** optical properties and applications of some representative bioinspired fluorescent polymers in bioimaging,sensing and imaging-guided therapy are also elucidated.

关键词： Green fluorescent protein Fluorescence Proteins Chromophores Polymers

A feasibility study on the design and walking operation of a biped locomotor via dynamic simulation

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Frontiers of Mechanical Engineering 2016年第2期11卷 144-158页

作者： mingfeng wang Marco CECCARELLI Giuseppe CARBONE School Of Mechanical and Electrical Engineering Central SouthUniversity Changsha 410083 China Laboratory of Robotics andMechatronics (LARM) DICeM University of Cassino and SouthLatium Cassino 03043 Italy Laboratory of Robotics and Mechatronics (LARM) DICeM Universityof Cassino and South Latium Cassino 03043 Italy

A feasibility study on the mechanical design and walking operation of a Cassino biped locomotor is presented in this paper. The biped locomotor consists of two identical 3 degrees-of-freedom tripod leg mechanisms with a parallel manipulator architecture. Planning of the biped walking gait is performed by coordinating the motions of the two leg mechanisms and waist. A three- dimensional model is elaborated in SolidWorks environ- ment in order to characterize a feasible mechanical design. Dynamic simulation is carried out in *** environment with the aims of characterizing and evaluat- ing the dynamic walking design. Simulation results performance of the proposed show that the proposed biped locomotor with proper input motions of linear actuators performs practical and feasible walking on fiat surfaces with limited actuation and reaction forces between its feet and the ground. A preliminary prototype of the biped locomotor is built for the purpose of evaluating the operation performance of the biped walking gait of the proposed locomotor.

关键词： feasibility study biped locomotor bipedwalking mechanical design dynamic simulation tripodleg mechanism 3-UPU parallel manipulator

Effects of miR-219/miR-338 on microglia and astrocyte behaviors and astrocyte-oligodendrocyte precursor cell interactions

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Neural Regeneration Research 2020年第4期15卷 739-747页

作者： Lan Huong Nguyen William Ong Kai wang mingfeng wang Dean Nizetic Sing Yian Chew School of Chemical and Biomedical Engineering Nanyang Technological UniversitySingaporeSingapore Lee Kong Chian School of Medicine Nanyang Technological UniversitySingaporeSingapore Blizard Institute Barts&The London School of MedicineQueen Mary University of LondonLondonUK NUS Synthetic Biology for Clinical and Technological Innovation(SynCTI) Life Sciences InstituteNational University of SingaporeSingapore

MiR-219 and miR-338(miR-219/miR-338)are oligodendrocyte-specific *** overexpression of these miRs in oligodendrocyte precursor cells promotes their differentiation and maturation into oligodendrocytes,which may enhance axonal remyelination after nerve injuries in the central nervous system(CNS).As such,the delivery of miR-219/miR-338 to the CNS to promote oligodendrocyte precursor cell differentiation,maturation and myelination could be a promising approach for nerve ***,nerve injuries in the CNS also involve other cell types,such as microglia and ***,we investigated the effects of miR-219/miR-338 treatment on microglia and astrocytes in vitro and in *** found that miR-219/miR-338 diminished microglial expression of pro-inflammatory cytokines and suppressed astrocyte *** addition,we showed that miR-219/miR-338 enhanced oligodendrocyte precursor cell differentiation and maturation in a scratch assay paradigm that re-created a nerve injury condition in ***,our results suggest miR-219/miR-338 as a promising treatment for axonal remyelination in the CNS following nerve *** experimental procedures were approved by the Institutional Animal Care and Use Committee(IACUC),Nanyang Technological University(approval No.A0309 and A0333)on April 27,2016 and October 8,2016.

关键词： central nervous system electrospinning gene silencing glia hydrogel myelination nanofibers oligodendroglial polycaprolactone spinal cord injury

Oceanic vertical mixing of the lower halocline water in the Chukchi Borderland and Mendeleyev Ridge

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Acta Oceanologica Sinica 2021年第11期40卷 39-49页

作者： Long Lin Hailun He Yong Cao Tao Li Yilin Liu mingfeng wang State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519082China Key Laboratory of Physical Oceanography Ministry of EducationQingdao 266003China

Oceanic vertical mixing of the lower halocline water(LHW)in the Chukchi Borderland and Mendeleyev Ridge was studied based on in situ hydrographic and turbulent *** depth-averaged turbulent dissipation rate of LHW demonstrates a clear topographic dependence,with a mean value of 1.2×10^(-9) W/kg in the southwest of Canada Basin,1.5×10^(-9) W/kg in the Mendeleyev Abyssal Plain,2.4×10^(-9) W/kg on the Mendeleyev Ridge,and2.7×10^(-9) W/kg on the Chukchi ***,the mean depth-averaged vertical heat flux of the LHW is0.21 W/m^(2) in the southwest Canada Basin,0.30 W/m^(2) in the Mendeleyev Abyssal Plain,0.39 W/m^(2) on the Mendeleyev Ridge,and 0.46 W/m^(2) on the Chukchi ***,in the presence of Pacific Winter Water,the upward heat released from Atlantic Water through the lower halocline can hardly contribute to the surface ***,the underlying mechanisms of diapycnal mixing in LHW—double diffusion and shear instability—was *** mixing in LHW where double diffusion were observed is always relatively weaker,with corresponding dissipation rate ranging from 1.01×10^(-9) W/kg to 1.57×10^(-9) W/*** results also show a strong correlation between the depth-average dissipation rate and strain variance in the LHW,which indicates a close physical linkage between the turbulent mixing and internal wave *** addition,both surface wind forcing and semidiurnal tides significantly contribute to the turbulent mixing in the LHW.

关键词： oceanic vertical mixing lower halocline water dissipation rate vertical heat flux

Investigation on the catalytic effects of AAEM during steam gasification and the resultant char reactivity in oxygen using Shengli lignite at different forms

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International Journal of Coal Science & Technology 2015年第3期2卷 223-231页

作者： Jianxin Mi Ningbo wang mingfeng wang Pengju Huo Dan Liu Hydrocarbon Research Center of Shaanxi YanchangPetroleum (Group) Co. Ltd. Xi'an 710075 China

The purpose of this study is to investigate the catalytic effects of alkali and alkaline earth metallic species （AAEM） on char conversion during the gasification in steam and the changes in ex-situ char reactivity in oxygen after the gasification in steam using different forms （i.e. H-form, Na-form） of Shengli brown coal. The surface area, AAEM concentration and carbon crystallite of chars were obtained to understand the change in char reactivity. It was found that not only Na concentration and carbon structure were the main factors governing the char reactivity in the atmosphere of steam and oxygen, but also they interacted each other. The presence of Na could facilitate the formation of disordering carbon structure in char, and the amorphous carbon structure would in turn affect the distribution of Na and thus its catalytic performance. The surface area and pore volume had very little relationship with the char＇s reactivity. Addi- tionally, the morphology of chars from different forms of coals were observed using scanning electron microscope （SEM）.

关键词： Steam gasification H-form coal Na-form coal Char reactivity Char structure

1→N quantum controlled phase gate realized in a circuit QED system

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Science China(Physics,Mechanics & Astronomy) 2012年第8期55卷 1422-1426页

作者： GAO GuiLong CAI GenChang HUANG.ShouSheng TANG LongYing GU WenJing wang mingfeng JIANG-NianQuan College of Physics and Electric Information Wenzhou University Wenzhou 325035 China College of Music Wenzhou University Wenzhou 325035 China

We propose an effective method to realize the quantum phase gate the system in which the transmon qubits are capacitively coupled to of one qubit simultaneously controlling N qubits. We use a superconducting transmission line resonator driven by a strong microwave field. In our scheme, the phase gate can be realized in a time （nanosecond-scale） much shorter than deco herence time （microsecond-scale）, and it is more immune to the l/（charge noise and has longer dephasing time due to the fa vorable properties of the transmon qubits in the system.

关键词： phase gate transmon qubit transmission line resonator

THE SYNTHESIS OF Ti-ZSM-5 STARTING WITH DE-[B]ZSM-5

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Chinese Journal of Catalysis 1997年第4期 8-9页

作者： Li mingfeng, Guo Xinwen, wang Xiangsheng * (Institute of Industrial Catalyst, Dalian University of Technology, Dalian 116012)

ＴＨＥＳＹＮＴＨＥＳＩＳＯＦＴｉ┐ＺＳＭ┐５ＳＴＡＲＴＩＮＧＷＩＴＨＤＥ┐［Ｂ］ＺＳＭ┐５ＬｉＭｉｎｇｆｅｎｇ，ＧｕｏＸｉｎｗｅｎ，ＷａｎｇＸｉａｎｇｓｈｅｎｇ＊（ＩｎｓｔｉｔｕｔｅｏｆＩｎｄｕｓｔｒｉａｌＣａｔａｌ... 详细信息

ＴＨＥＳＹＮＴＨＥＳＩＳＯＦＴｉ┐ＺＳＭ┐５ＳＴＡＲＴＩＮＧＷＩＴＨＤＥ┐［Ｂ］ＺＳＭ┐５ＬｉＭｉｎｇｆｅｎｇ，ＧｕｏＸｉｎｗｅｎ，ＷａｎｇＸｉａｎｇｓｈｅｎｇ＊（ＩｎｓｔｉｔｕｔｅｏｆＩｎｄｕｓｔｒｉａｌＣａｔａｌｙｓｔ，ＤａｌｉａｎＵｎｉｖｅｒｓ...

关键词： Ti ZSM 5 zeolite De ZSM 5 zeolite Isomorphous replacement Cyclohexanone Ammoxidation

Polyester-tethered near-infrared fluorophores confined in colloidal nanoparticles:Tunable and thermoresponsive aggregation and biomedical applications

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Aggregate 2023年第2期4卷 193-205页

作者： Cangjie Yang Wei Zhang Xin Pang Fan Xiao Sandeep Kumar Kalva Yipeng Zhang Manojit Pramanik Leilei Tian Gang Liu mingfeng wang School of Chemical and Biomedical Engineering Nanyang Technological UniversitySingaporeSingapore School of Science and Engineering The Chinese University of Hong KongShenzhenChina State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics&Center for Molecular Imaging and Translational Medicine School of Public HealthXiamen UniversityXiamenChina School of Materials Science and Engineering South University of Science and TechnologyShenzhenChina Institute of Pharmacology and Toxicology and Institute of Biomedical Engineering Faculty of MedicineUniversity of ZurichZurich CH-8057Switzerland

Intricate assembly of multiple molecular chromophores assisted by protein scaffolds is essential in tuning the optical absorption and energy transfer in the light-harvesting complexes of the photosynthetic systems in ***,it remains a challenge to achieve such structural complexity and functionality in synthetic polymer-chromophore ***,we report a series of polyester-tethered pyrrolopyrrole cyanine derivatives and their colloidal nanoparticles dispersed in water,which show tunable J-or H-aggregation excitonic coupling and near-infrared fluorescence by precise control of the polymer chain lengths,composition,and ***,the optimal fluorescence or photothermal effect of the Jaggregate nanoparticles enables broad applications in fluorescence or photoacoustic bioimaging and phototherapy.

关键词： bioimaging colloids fluorescence polymers self-assembly

权力-空间视角下城市文创旅游空间的生产与演化——以上海田子坊为例

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地理研究 2022年第2期41卷 373-389页

作者：汪明峰周媛华东师范大学中国现代城市研究中心上海200062 华东师范大学中国行政区划研究中心上海200241 华东师范大学城市与区域科学学院上海200241

近年来,旧城更新形成的文化创意产业园向旅游目的地转型已成为普遍趋势。既有研究对文创园区和旅游地形成的空间生产机制有所挖掘,但对文创产业园旅游转向的内生性动力的认识有待深入。本文结合列斐伏尔的三元空间理论和福柯的权力空间... 详细信息

近年来,旧城更新形成的文化创意产业园向旅游目的地转型已成为普遍趋势。既有研究对文创园区和旅游地形成的空间生产机制有所挖掘,但对文创产业园旅游转向的内生性动力的认识有待深入。本文结合列斐伏尔的三元空间理论和福柯的权力空间思想,采用实地调研、深度访谈与半沉浸式观察相结合的综合方法,从宏观-微观互动的角度对田子坊文创旅游空间的生产和演化机制进行研究。结果表明:①各行动主体基于社会关系和空间主权形成权力-空间关系;②为实现增长的集体目标,城市政府引导了具有生产性逻辑的空间制度设计,并与微观行动者进行权力的分配与互动,形成空间规训和生产机制;③在表征的空间中,商户的日常生活实践通过多样化的服从与抵抗的能动性策略,形成差异化的微观空间生产,推动文创旅游的空间实践与演化。研究还针对文创园区旅游化进程中存在的问题提供了治理启示。

关键词：权力-空间空间的生产文创旅游商业空间空间形态演化田子坊