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Doctor communication quality and Friends' attitudes influence complementary medicine use in inflammatory bowel disease

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World Journal of Gastroenterology 2015年第12期21卷 3663-3670页

作者： Réme Mountifield Jane M Andrews Antonina Mikocka-Walus Peter Bampton Department of Gastro-enterology and Hepatology Flinders Medical Centre Flinders University of South Australia IBD Service Department of Gastroenterology and Hepatology and School of Medicine University of Adelaide at Royal Adelaide Hospital School of Nursing and Midwifery University of South Australia

AIM: To examine the frequency of regular complementary and alternative therapy(CAM) use in three Australian cohorts of contrasting care setting and geography, and identify independent attitudinal and psychological predictors of CAM use across all cohorts. meTHODS: A cross sectional questionnaire was administered to inflammatory bowel disease(IBD) patients in 3 separate cohorts which differed by geographical region and care setting. Demographics and frequency of regular CAM use were assessed, along with attitudes towards IBD medication and psychological parameters such as anxiety, depression, personality traits and quality of life(QOL), and compared across cohorts. Independent attitudinal and psychological predictors of CAM use were determined using binary logistic regression analysis. RESULTS: In 473 respondents(mean age 50.3 years, 60.2% female) regular CAM use was reported by45.4%, and did not vary between cohorts. Only 54.1%of users disclosed CAM use to their doctor. Independent predictors of CAM use which confirm those reported previously were: covert conventional medication dose reduction(P ment(P medication(P = 0.043), and higher QOL(P < 0.001).Newly identified predictors were CAM use by family or friends(P < 0.001), dissatisfaction with patient-doctor communication(P < 0.001), and lower depression scores(P < 0.001). CONCLUSION: In addition to previously identified predictors of CAM use, these data show that physician attention to communication and the patient-doctor relationship is important as these factors influence CAM use. Patient reluctance to discuss CAM with physicians may promote greater reliance on social contacts to influence CAM decisions.

关键词： Complementary medicine Alternative therapy Therapy

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Near-Earth bursty bulk flows and AE index

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Science China(Technological Sciences) 2008年第10期51卷 1704-1712页

作者： W BAUMJOHANN M. W. DUNLOP C. CARR H. Rme Space Research Institute Austrian Academy of Sciences Graz Austria Space Sciences Division Rutherford Appleton Laboratory Chilton Didcot UK Imperial College London United Kingdom Centre d'Etude Spatiale des Rayonnements Toulouse France

With the 4-s resolution data of the magnetometer and the ion plasma analyzer on TC-1 from June to November of each year during the period of 2004―2006, we statistically analyzed the occurrence rate of both convective and field-aligned bursty flows (FABFs). A near-Earth bursty bulk flow (NEBBF) occurred during both the quiet time and substorm process. In general, the magnetic field and the plasma density began oscillating with the appearance of the NEBBF associated with a distinct increase of the AE index. The increase of AE index during the NEBBF was more than 100 nT in both quiet time and substorm process. The statistical analysis indicated that the occurrence rates of the FABFs were nearly the same in the dif-ferent stages of the AE index, but the occurrence rate of the NEBBFs was much higher in the growth stage of the AE index, indicating that the NEBBFs were di-rectly related to the growth and expansion phases of the substorm. The observa-tions suggested that the quite large number of BBFs from the mid magnetotail could enter into the near-Earth tail and play important role in triggering the sub-storm onset.

关键词： BBF near-Earth AE index substorm onset

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Nonadiabatic acceleration of plasma sheet ions related to ion cyclotron waves

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Science China(Technological Sciences) 2014年第12期57卷 2434-2440页

作者： WANG Zhi Qiang CAO Jin Bin Rme Henri DANDOURAS Iannis MA Yu Duan Department of Space Science and Application College of Astronautics Nanjing University of Aeronautics and Astronautics University of Toulouse UPS-OMP IRAP Toulouse 31082 France The French National Centre for Scientific Research The Research Institute in Astrophysics and Planetology Space Science Institute School of Astronautics Beihang University

The nonadiabatic acceleration of plasma sheet ions is important to the understanding of substorm energetic injections and the formation of ring current. Previous studies show that nonadiabatic acceleration of protons by magnetic field dipolarization is hard to occur at X>–10 RE because the time-scale of dipolarization(several minutes) is much larger than the gyroperiod of protons there(several seconds). In this paper, we present a case of nonadiabatic acceleration of plasma sheet ions observed by Cluster on October 30, 2006 at(XGSM, YGSM)=(-7.7, 4.7) RE. The nonadiabatic acceleration of ions is caused not by previously reported magnetospheric dipolarization but by the ultra low frequency(ULF) waves during magnetospheric dipolarization. The nonadiabatic acceleration of ions generates a new energy flux structure of ions, which is characterized by the usual energy flux increase of ions(28–80 ke V) and a concurrent energy flux decrease of ions in a lower energy range(10 e V–20 ke V). These new observations constitute a complete physical picture: The lower energy ions absorb the wave energy, and thus get accelerated to higher energy. We use a nonadiabatic model to interpret the ion energy flux variations. Both analytic and simulation results are in good agreement with the observations. This indicates that the nonadiabatic acceleration associated with ULF waves superposed on dipolarized magnetic field is an effective mechanism for ion energization in the near-Earth plasma sheet. The presented energy flux structures can be used as a proxy to identify the similar dynamic process.

关键词： nonadiabatic acceleration ion cyclotron waves wave-particle interaction

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Comparison of long-term outcome between patients aged 〈 65 years vs. ≥ 65 years after atrial fibrillation ablation

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Journal of Geriatric Cardiology 2017年第9期14卷 569-574页

作者： Zsuzsanna Kis Anna me Noten Mihran Martirosyan Astrid A Hendriks Rohit Bhagwandien Tamas Szili-Torok Department of Cardiology Erasmus MC University Medical Center Rotterdam the Netherlands

Background Atrial fibrillation （AF） is the most frequent arrhythmia, and its prevalence is increasing with aging. We aimed to com-pare the long-term outcome data of patients 〈 65 years vs.≥ 65 years who underwent catheter ablation （CA） for drug-refractory AF. methodsConsecutive patients with primary pulmonary vein isolation performed between March 2001 and December 2011, and those who completeda five-year of follow-up were divided into two groups： patients aged 〈 65 years into group 1, and patients aged ≥ 65 into group 2. Long-termoutcome data concerning mortality, thromboembolic events （TE） and success rates were compared between these groups. Results A totalnumber of 390 patients were included, group 1 contained 310 patients, and 80 patients in group 2. In group 2, patients had more often impairedrenal function （P 〈 0.001） and thyroid disease （P = 0.047）. A total of fifteen patients died during the 6.63 ± 2.1 years of follow-up, with a sig-nificantly higher incidence in the older group （8/80 vs. 7/310 patients, P = 0.004）. The majority of fatal outcome was due to cancerous dis-eases in both groups. No difference was observed concerning the long-term TE rate （12/310 vs. 4/80 patients, P = 0.75）. Rhythm controlfailed in 25.9% of the patients, with no difference between the groups： 26.4% in group 1 vs. 23.7% in group 2 （P = 0,67）, ConclusionsDespite growing prevalence of AF in aging population, the elderly patients are underrepresented in CA procedures. Similar clinical successand TE complication rate are observed between the age-groups. Our data suggest more liberal criteria might be applied while selecting pa-tients for AF ablation.

关键词： Atrial fibrillation Catheter ablation Clinical outcome The elderly Thromboembolic complication

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Use of Large-Eddy Simulation for the bed shear stress estimation over a dune

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International Journal of Sediment Research 2021年第6期36卷 687-695页

作者： Adrien Bourgoin Sylvain S.Guillou Jér?me Thiébot Riadh Ata Normandy University University of Caen Normandy Normandy University University of Caen Normand

Environmental flows are generally characterized by complex bed morphology and high current *** configurations favor the formation of vortex structures that strongly affect hydrody-namics and sediment transport. Large-Eddy Simulation(LES) enables investigation of the dynam-ics of the largest turbulence scales and, thanks to enhanced calculation resources, has now become applicable for simulating environmental flows. In this paper, a LES approach is developed in a CFD code(TELEMAC-3 D),which was originally developed to simulate free surface flows using RANS methods. The present developments involve implementing subgrid models, boundary con-ditions and numerical schemes suitable for LES. The LES version of TELEMAC-3 D was validated by comparing results on the model with experimental data for flow past a cylinder. Then, the model was applied to a test case representing flow over dunes. After validating the hydrodynamics, the model was used to assess the bottom shear stress,using both a RANS and a LES approach. Com-parison highlighted the potential contribution of LES to investigating the hydrodynamic forces acting on the bottom.

关键词： Turbulence Environmental flows Large eddy simulations Bed shear stress

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Solar wind transport into magnetosphere caused by magnetic reconnection at high latitude magnetopause during northward IMF: Cluster-DSP conjunction observations

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Science China(Technological Sciences) 2008年第10期51卷 1677-1684页

作者： M. DUNLOP E. LUCEK H. Rme C. M. CARR Rutherford Appleton Laboratory Didcot United Kingdom Imperial College of Science Technology and Medicine London United Kingdom CESR BP4346 31028 Toulouse Cedex 4 France

An event of Cluster-Double Star conjunction observations of magnetic reconnec-tion at high latitude magnetopause nightside of both cusps and solar wind trans-port into magnetosphere caused by such reconnection process has been investi-gated. During northward IMF, Cluster/SC1 observed accelerated flows and ion heating associated with magnetic reconnection at high latitude magnetopause nightside of southern cusp. And Double Star observed cold dense solar wind plasma transported into dayside magnetosphere. The analysis on such conjunction observations shows that: (1) during northward IMF, magnetic reconnection occurs at high latitude nightside of southern cusp, accompanied by accelerated flows that are observed by Cluster/SC1; (2) the direction of the accelerated flows, with its sunward component Vx, dawnward component Vy, northward component Vz, is quite consistent with the theoretical anticipation under the condition of northward IMF with dawnward component By; (3) reconnection can heat plasma more in par-allel direction than in perpendicular direction, to a level of about 4 keV; (4) with reconnection taking place at high latitude magnetopause nightside of the southern cusp, TC-1 observed cold and dense plasma transported into magnetosphere; (5) by reconnection at high latitude magnetopause nightside of both cusps, solar wind flux tube can be captured by magnetosphere and pulled into dayside magneto-sphere. This event presents further observational evidence for magnetic reconnec-tion at high latitude magnetopause nightside of both cusps as an important mech-anism of sol-ar w-ind transport into magnetosphere.

关键词： transport process magnetic reconnection solar wind-magnetosphere interactions

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Superconducting parameter determination for (Co0.5Zn0.5Fe2O4)x/Cu0.5Tl0.5-1223 composite

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Journal of Advanced Ceramics 2016年第3期5卷 210-218页

作者： M.me.BARAKAT N.AL-SAYYED R.AWAD A.I.ABOU-ALY Physics Department Faculty of Science Alexandria University Alexandria Egypt Physics Department Faculty of Science Beirut Arab University Beirut Lebanon

The addition of magnetic Co0.5Zn0.5Fe2O4 nanoparticles to the superconducting Cu0.5Tl0.5-1223 phase has been used to investigate the electrical resistivity behavior of the composite above the superconducting transition temperature Tc. This was studied according to the opening of spin gap and fluctuation conductivity. The results indicated that the pseudogap temperature (T*) and superconducting fluctuation temperature (Tscf) change by increasing the addition of Co0.5Zn0.5Fe2O4 nanoparticles. It was found that T* is related to hole carrier concentration P and it also depends on the antiferromagnetic fluctuation affected by magnetic nanoparticles. The excess-conductivity analysis showed four different fluctuation regions started from high temperature up to Tc, and they were denoted by short wave (sw), two-dimensional (2D), three-dimensional (3D), and critical (cr) fluctuations. The crossover temperature between 3D and 2D (T3D-2D) in the mean field region was decreased by increasing the addition of Co0.5Zn0.5Fe2O4 nanoparticles, in accordance with the decrease in Tscf with x. The coherence length at 0 K along c-axis ξc(0), effective layer thickness of the 2D system d, and inter-layer coupling strength J were estimated as a function of Co0.5Zn0.5Fe2O4 nanoparticle addition. Moreover, the thermodynamics, lower and upper critical magnetic fields, as well as critical current density have been calculated from the Ginzburg number NG. It was found that the low concentration of Co0.5Zn0.5Fe2O4 nanoparticles up to x = 0.08 wt% improves the superconducting parameters of Cu0.5Tl0.5-1223 phase. On the contrary, these parameters were deteriorated f

关键词： Co0.5Zn0.5Fe2O4 nanoparticles Cu0.5Tl0.5-1223 phase pseudogap temperature fluctuation conductivity

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Overexpression of the angiogenic tetrapeptide AcSDKP and the prolyl oligopeptidase(POP) is a common feature of cancer

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生物物理学报 2009年第S1期25卷 32-33页

作者： Jérme Bignon Alexia Pinault Joanna Wdzieczak-Bakala Institut de Chimie des Substances Naturelles CNRS 91198 Gif-sur-Yvette France

Prolyl oligopeptidase (POP) is a cytosolic enzyme involved in the metabolism of many peptide hormones and neuropeptides (1). It was recently reported that POP is responsible

关键词： AcSDKP Overexpression of the angiogenic tetrapeptide AcSDKP and the prolyl oligopeptidase is a common feature of cancer POP

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Network of GRAS transcription factors in plant development,fruit ripening and stress responses

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Horticulture Research 2023年第12期10卷 286-303页

作者： Catarina Neves Beatriz Ribeiro Rute Amaro Jesús Expósito Jérôme Grimplet Ana Margarida Fortes BioISI-Biosystems and Integrative Sciences Institute Faculty of SciencesUniversity of LisbonCampo Grande1749-016 LisboaPortugal Centro de Investigación y Tecnología Agroalimentaria de Aragón(CITA) Departamento de Ciencia VegetalGobierno de AragónAvda.Montañana 93050059 ZaragozaSpain Instituto Agroalimentario de Aragón-IA2(CITA-Universidad de Zaragoza) Calle Miguel Servet 17750013 ZaragozaSpain

The plant-specific family of GRAS transcription factors has been wide implicated in the regulation of transcriptional reprogramming associated with a diversity of biological functions ranging from plant development processes to stress *** analyses of GRAS transcription factors supported by in silico structural and comparative analyses are emerging and clarifying the regulatory networks associated with their biological *** this review,a detailed analysis of GRAS proteins’structure and biochemical features as revealed by recent discoveries indicated how these characteristics may impact subcellular location,molecular mechanisms,and *** issues associated with GRAS classification into different subfamilies in diverse plant species even in the presence of robust genomic resources are discussed,in particular how it affects assumptions of biological *** into the mechanisms driving evolution of this gene family and how genetic and epigenetic regulation of GRAS contributes to subfunctionalization are ***,this review debates challenges and future perspectives on the application of this complex but promising gene family for crop improvement to cope with challenges of environmental transition.

关键词： function GRAS plant

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Solar wind entry via flux tube into magnetosphere observed by Cluster measurements at dayside magnetopause during southward IMF

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Science China(Technological Sciences) 2009年第7期52卷 2104-2111页

作者： M. Dunlop A. Balogh H. Rème Y. V. Bogdanova A. Fazakerley Rutherford Appleton Laboratory Didcot United Kingdom Imperial College of Science Technology and Medicine London United Kingdom CESR BP4346 31028 Toulouse Cedex 4 France Mullard Space Science Laboratory Dorkink United Kingdom Department of Physics La Trobe University Victoria 3086 Australia

By analyzing hot ion and electron parameters together with magnetic field measurements from Cluster, an event of magnetopause crossing of the spacecraft has been investigated. At the latitude of about 40° and magnetic local time (MLT) of 13:20 during the southward interplanetary magnetic field (IMF), a transition layer was observed, with the magnetospheric field configuration and cold dense plasma features of the magnetosheath. The particle energy-time spectrograms inside the layer were similar to but still a little different from those in the magnetosheath, obviously indicating the solar wind entry into the magnetosphere. The direction and magnitude of the accelerated ion flow implied that reconnection might possibly cause such a solar wind entry phenomenon. The bipolar signature of the normal magnetic component BN in magnetopause coordinates further supported happening of reconnection there. The solar wind plasma flowed toward the magnetopause and entered the magnetosphere along the reconnected flux tube. The magnetospheric branch of the reconnected flux tube was still inside the magnetosphere after reconnection and supplied the path for the solar wind entry into the dayside magnetosphere. The case analysis gives observational evidence and more details of how the reconnection process at the dayside low latitude magnetopause caused the solar wind entry into the magnetosphere.

关键词： transport process magnetic reconnection solar wind-magnetosphere interactions

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