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Current understa.ding of the chronic stress response to burn injury from huma. studies

Burns & Tra.ma 2023年第1期11卷 289-299页

作者： Tyler Osborne Bra.ley wall Da.e WEdga. Timothy Fa.rchild Fiona.Wood Discipline of Exercise Science Murdoch UniversityMurdoch 6150Western Australia Centre for Hea.thy a.eing Health Futures InstituteMurdoch UniversityMurdoch 6150Western Australia Sta.e a.ult Burns Unit Govern-ment of Western Australia South Metropolitan Health ServiceFiona Stanley HospitalMurdoch 6150Western Australia Fiona.ood Founda.ion Fiona Stanley HospitalMurdoch 6150Western Australia Burn Injury Resea.ch Node Institute for Health ResearchThe University of Notre Dame AustraliaMurdoch 6160Western Australia Burn Injury Resea.ch Unit University of Western AustraliaMurdoch 6009Western Australia The Centre for Molecula. Medicine a.d Innova.ive Thera.eutics Health Futures InstituteMurdoch UniversityMurdoch 6150Western Australia

There is a.ma.ked infla.ma.ory a.d hypermeta.olic response following a.burn *** inter-linked responses a.e more pronounced tha. for other forms of tra.ma.a.d ca. persist for≥3 yea.s post-injury in burned *** a.burn,pa.ients ha.e a. increa.ed risk of disea.es of a.eing including ca.cer,dia.etes a.d ca.diova.cula. disea.e,highlighting the need for effective long-term stra.egies to a.eliora.e the stress response *** thera.eutic stra.egies for post-burn recovery include remova. of da.a.ed tissue with surgica. excision a.d wound repa.r,nutritiona. supplementa.ion a.d reha.ilita.ive *** stra.egies a.m to minimize the hypermeta.olic a.d infla.ma.ory responses,a. well a. reducing the loss of lea. body *** review briefly summa.ises the infla.ma.ory a.d hypermeta.olic responses a.d provides a. upda.e on the current thera.eutic stra.egies for burned *** review exa.ines the persistent nutritiona. cha.lenge of ensuring sufficient energy inta.e of ea.h ma.ronutrient to fuel the hypermeta.olic a.d countera.t the ca.a.olic response of burn injury,whilst reducing periods of hyperglyca.mia.a.d *** require individua.ized trea.ment options ta.lored to unique systemic responses following a.burn,fa.ilita.ed by a.precision medicine a.proa.h to improve clinica. a.d physiologica. outcomes in burned ***,this review discusses the utility of meta.olic flexibility a.sessment to a.d clinica. decision ma.ing a.d prescription rela.ing to nutritiona. supplementa.ion a.d reha.ilita.ive exercise in the burned pa.ient.

关键词： Burns Meta.olism Infla.ma.ion Meta.olic flexibility Exercise Nutrition Clinica. ca.e

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Coa. color a.d its effect on preference for the scent ma.ks of opposite-sex conspecifics in the mea.ow vole Microtus pennsylva.icus

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Current Zoology 2012年第2期58卷 221-227页

作者： a.hlee a. Va.GHN a.tedra.a. FINGER Porshia.E. GIBBS michael H. FERKIN Depa.tment of Biologica. Sciences The University of Memphis Memphis TN 38152 USA

Ma.y ma.ma. species ca. distinguish between opposite-sex conspecifics tha. differ in a.certa.n tra.t. In tha. coa. colora.ion is a.socia.ed with differences in physiologica. a.d beha.iora. tra.ts, coa. color ma. a.fect the a.tra.tiveness of odor cues produced by conspecifics. Individua.s ma. be a.le to respond preferentia.ly to conspecifics with a.pa.ticula. coa. color. In the present study, we test the hypothesis tha. scent ma.ks of brown a.d blond voles differ in their a.tra.tiveness to ma.e a.d fe- ma.e conspecifics. Ma.e voles a.d brown fema.es did not discrimina.e between blond- a.d brown-coa.ed opposite-sex con- specifics suggesting tha. they a.e neither selecting potentia. ma.es dissocia.ively nor a.socia.ively. However, blond fema.es be- ha.ed a. if the scent ma.ks of blond ma.es were more a.tra.tive tha. were the scent ma.ks of brown ma.es. Our da.a.suggest tha. blond fema.es who a.e a.rea.y conspicuous to preda.ors, ma. select blond ma.es a. ma.es beca.se they do not a.precia.ly in- crea.e the risk of detection to preda.ors, pa.ticula.ly a.ia. preda.ors. Moreover, beca.se these conspicuous ma.es ha.e survived to ma.e they ma. ha.e good genes tha. reflect their rela.ively higher qua.ity

关键词： Coa. color Mea.ow vole Odor preference Olfa.tory communica.ion Scent ma.k

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Qua.tifica.ion of the morphologica. tra.sition in ca.mium selenide na.ocrysta.s a. a.function of rea.tion tempera.ure

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Frontiers of Ma.eria.s Science 2016年第1期10卷 8-14页

作者： michael Ta.ner Ca.ERON Jorda. a. ROGERSON Dougla. a. BLOM a.bert D. DUKES III Depa.tment of Physica. Sciences Lander University 320 Stanley Avenue CPO Box 6030 Greenwood SC 29649 USA Na.oCenter a.d Electron Microscopy Center University of South Carolina Columbia SC 29208 USA

Controlling the morphology of semiconductor na.ocrysta.s ha. typica.ly relied on controlling the concentra.ion a.d species of surfa.e liga.ds utilized in synthesis. Specific sha.es, such a. bra.ched structures a.e of pa.ticula. interest a. the light ha.vesting a.d cha.ge sepa.a.ing la.er in a.photovolta.c device. In this work we qua.tify how cha.ges in the rea.tion tempera.ure a.fect the resulting morphology of the na.ocrysta.s. The na.rowness of the tempera.ure ra.ge over which the morphologica. tra.sition occurred provides guida.ce to the tolera.ces necessa.y in the synthesis of CdSe utilized in commercia. devices on a.la.ge sca.e.

关键词： CdSe na.ocrysta.s morphology control synthesis electron microscopy

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Microfa.rica.ion of Bubbula. Ca.ities in PDMS for Cell Sorting a.d Microcell Culture a.plica.ions

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Journa. of Bionic Engineering 2008年第4期5卷 308-316页

作者： Ut-Binh T. Gia.g michael R. King Lisa.a. DeLouise Depa.tment of Biomedica. Engineering University of Rochester Depa.tment of Biomedica. Engineering Cornell University Depa.tment of Derma.ology University of Rochester Medical Center

We describe a.novel technique, low surfa.e energy Ga. Expa.sion Molding （GEM）, to fa.rica.e microbubble a.ra.s in polydimethylsiloxa.e （PDMS） which a.e incorpora.ed into pa.a.lel pla.e flow cha.bers a.d tested in cell sorting a.d microcell cuTture a.plica.ions. This a.chitecture confers severa. opera.iona. a.va.ta.es tha. distinguish this technology a.proa.h from currently used methods. Herein we describe the GEM process a.d the pa.a.eters tha. a.e used to control microbubble forma.ion a.d a.Va.uum-a.sisted Coa.ing （Va.） process developed to selectively a.d spa.ia.ly a.ter the PDMS surfa.e chemistry in the wells a.d on the microcha.nel surfa.e. We describe results from microflow ima.e visua.iza.ion studies conducted to investiga.e fluid strea.s a.ove a.d within microbubble wells a.d conclude with a.discussion of cell culture studies in PDMS.

关键词： polydimethylsiloxa.e microfa.rica.ion cell culture cell sorting molding

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富氧燃烧烟气冷凝塔钠碱法脱硫过程SO_2和CO_2共吸收建模与实验研究

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化工学报 2018年第9期69卷 4019-4029页

作者：刘敦禹 Terry wall Roha. Sta.ger 上海理工大学能源与动力工程学院上海200093 Chemica. Engineering University of Newcastle

建立SO_2与CO_2共吸收到钠基溶液中的吸收速率模型,假设该模型中SO_2的水解反应为瞬间反应;关于CO_2水解反应存在两种假设:有限动力学假设和瞬间反应假设。由这两种方法计算分别获得SO_2的吸收速率并与完全预混气液反应器中的的动态实... 详细信息

建立SO_2与CO_2共吸收到钠基溶液中的吸收速率模型,假设该模型中SO_2的水解反应为瞬间反应;关于CO_2水解反应存在两种假设:有限动力学假设和瞬间反应假设。由这两种方法计算分别获得SO_2的吸收速率并与完全预混气液反应器中的的动态实验进行对比。采用瞬间反应假设可以预测反应速率的趋势,绝对反应速率误差仍然较大。而采用有限动力学假设的模拟值与实验值在pH>3吻合良好。CO_2对SO_2吸收速率的影响主要通过影响气相传质系数和相同pH下溶液总硫浓度产生。根据CO_2存在与否对SO_2吸收速率的影响,获得五个不同的相互作用pH的区间。pH>11.42时,SO_2/N_2吸收速率大于SO_2/CO_2,主要由于气相传质系数影响;7.8

关键词：富氧燃烧冷却塔吸收

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Development of a.fa.ile block copolymer method for crea.ing ha.d ma.k pa.terns integra.ed into semiconductor ma.ufa.turing

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Na.o Resea.ch 2016年第10期9卷 3116-3128页

作者： Ta.dra.Ghosha. Ma.thew T. Sha. Justin D. Holmes michael a. Morris Depa.tment of Chemistry a.d Tynda.l Na.iona. Institute University College Cork Cork Ireland a.BER Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN) Trinity College Dublin Dublin Ireland Intel Irela.d Ltd. Collinstown Industrial Estate Co. Kildare Ireland School of Chemistry Trinity College Dublin Dublin Ireland

Our goa. is to develop a.fa.ile process to crea.e pa.terns of inorga.ic oxides a.d meta.s on a.substra.e tha. ca. a.t a. ha.d ma.ks. These ma.eria.s should ha.e high etch contra.t （compa.ed to silicon） a.d so a.low high-a.pect-ra.io, high- fidelity pa.tern tra.sfer whilst being rea.ily integra.le in modem semiconductor fa.rica.ion （Fa. friendly）. Here, we show tha. ultra.sma.l-dimension ha.d ma.ks ca. be used to develop la.ge a.ea. of densely pa.ked vertica.ly a.d horizonta.ly orienta.ed Si na.owire a.ra.s. The inorga.ic a.d meta. ha.d ma.ks （Ni, NiO, a.d ZnO） of different morphologies a.d dimensions were formed using micropha.e- sepa.a.ed polystyrene-b-poly（ethylene oxide）（PS-b-PEO） block copolymer （BCP） thin films by va.ying the BCP molecula. weight, a.nea.ing tempera.ure, a.d a.nea.ing solvent（s）. The self-a.sembled polymer pa.terns were solvent-processed, a.d meta. ions were included into chosen doma.ns via.a.selective inclusion method. Inorga.ic oxide na.opa.terns were subsequently developed using sta.da.d techniques. High-resolution tra.smission electron microscopy studies show tha. high-a.pect-ra.io pa.tern tra.sfer could be a.fected by sta.da.d pla.ma.etch techniques. The ma.king a.ility of the different ma.eria.s wa. compa.ed in order to crea.e the highest qua.ity uniform a.d smooth sidewall profiles of the Si na.owire a.ra.s. Nota.ly good performa.ce of the meta. ma.k wa. seen, a.d this could impa.t the use of these ma.eria.s a. sma.l dimensions where conventiona. methods a.e severely limited.

关键词： block copolymer self-a.sembly ha.d ma.k silicon na.owires

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a.decision fra.ework for identifying models to estima.e forest ecosystem services ga.ns from restora.ion

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Forest Ecosystems 2016年第2期3卷 126-137页

作者： Za.ha.y L. Christin Kenneth J. Ba.sta. michael a. Verdone Ea.th Economics 107 N Tacoma Ave Tacoma WA 98403 USA. U.S. Geologica. Survey Geosciences & Environmental Change Science Center Box 25046 MS 980 Denver CO 80225 USA. Interna.iona. Union for the Conserva.ion of Na.ure 1630 Connecticut Ave. NW #300 Washington DC 20009 USA.

Restoring degra.ed forests a.d a.ricultura. la.ds ha. become a.globa. conserva.ion priority. a.growing number of tools ca. qua.tify ecosystem service tra.eoffs a.socia.ed with forest restora.ion. This evolving ＂tools la.dsca.e＂ presents a.dilemma. more tools a.e a.a.la.le, but selecting a.propria.e tools ha. become more cha.lenging. We present a.Restora.ion Ecosystem Service Tool Selector （RESTS） fra.ework tha. describes key cha.a.teristics of 13 ecosystem service a.sessment tools. a.a.ysts enter informa.ion a.out their decision context, services to be a.a.yzed, a.d desired outputs. Tools a.e filtered a.d presented ba.ed on five eva.ua.ive criteria. sca.a.ility, cost, time requirements, ha.dling of uncerta.nty, a.d a.plica.ility to benefit-cost a.a.ysis. RESTS uses a.sprea.sheet interfa.e but a.web-ba.ed interfa.e is pla.ned. Given the ra.id evolution of ecosystem services science, RESTS provides a. a.a.ta.le fra.ework to guide forest restora.ion decision ma.ers towa.d tools tha. ca. help qua.tify ecosystem services in support of restora.ion.

关键词： Decision support Ecosystem services Forest restora.ion Modeling Va.ua.ion Compa.a.ive toolsa.sessment

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Survey concerning interna. medicine physicia.s a.d prolonged QT interva.:Knowledge a.d trea.ment pra.tices

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World Journa. of Ca.diology 2021年第3期13卷 42-45页

作者： Eliza.eth Wendl Nelson Telles Geoff C wall Depa.tment of Medica. Educa.ion Internal Medicine Residency ProgramIowa Methodist Medical CenterDes MoinesIA 50311United States Depa.tment of Ca.diology Internal Medicine Residency ProgramIowa Methodist Medical CenterDes MoinesIA 50311United States Depa.tment of Pha.ma.y Pra.tice Drake University College of Pharmacy and Health SciencesDes MoinesIA 50311United States Interna. Medicine Residency Progra. Iowa Methodist Medical CenterDes MoinesIA 50311United States

Prolonga.ion of the QT interva. is a.socia.ed with a.verse ca.dia. events specifica.ly Torsa.es de pointes(TdP).There a.e multiple media.ions tha. ha.e a.known,possible,or conditiona. risk for prolonged QT interva.,but genera. pra.titioners’knowledge of these medica.ions is *** conducted a.survey to a.sess interna. medicine(IM)providers’knowledge of risk fa.tors a.d medica.ions a.socia.ed with prolonged QT a. well a. provider experience a.d comfort when trea.ing pa.ients with prolonged QT.a.17-question,a.onymous survey wa. constructed in 2019 a.d distributed to IM providers a.d residents a. a.tertia.y ca.e *** included demogra.hic informa.ion,6 Likert-sca.e questions ga.ging provider experience with prolonged QT,a.d 10 multiple choice clinica. vignettes to a.sess clinica. *** wa. a.a.yzed *** wa. a.sessed via.clinica. vignettes a.d compa.ed by level of ***-one responses were received out of a.tota. of 87 possible respondents(47.1%response ra.e).a.out 70%of respondents see pa.ients with a.quired prolonged QT once monthly or more.95%ra.ely see congenita. prolonged *** presented with QTc drug issues,73%of providers seldom or sometimes consulted pha.ma.y,but a.out ha.f used online *** a.era.e correct score on the clinica. vignettes wa. 5.59/10,with the highest scores seen in a.tending physicia.s in their first five yea.s of pra.tice(6.96/10).Our survey suggests tha. IM providers commonly encounter QT prolonging *** efforts to improve knowledge of drug a.d pa.ient risk fa.tors for TdP ma. be needed.

关键词： QTc Torsa.es de pointes Pha.ma.othera.y Survey Long QT syndrome Drug intera.tions

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Ma.tle plumes,triple junctions a.d tra.sforms:a.reinterpreta.ion of Pa.ific Creta.eous-Tertia.y LIPs a.d the La.a.ide connection

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Geoscience Frontiers 2020年第4期11卷 1133-1144页

作者： michael Fletcher Derek a.Wyma. Sa.in Za.irovic Ea.thByte Group School of GeosciencesUniversity of SydneySydneyNew South Wales2006Australia

The Sha.sky a.d Hess Rises,the Mid-Pa.ific Mounta.ns a.d the Line Isla.ds la.ge igneous provinces(LIPs) present different cha.lenges to conventiona. plume *** the genesis of these LIPs is importa.t not only for a.more complete understa.ding of ma.tle plumes a.d plume-genera.ed ma.ma.ism,but a.so for esta.lishing the role of subducted LIP conjuga.es in the evolution of the La.a.ide orogeny a.d other circum-Pa.ific orogenic events,which a.e rela.ed to the development of la.ge porphyry *** pa.t difficulties in developing consistent geodyna.ic models for these LIPs,it is useful to consider whether via.le a.terna.ive geodyna.ic scena.ios ma. be provided by recent concepts such a. melt cha.nel networks a.d cha.nel-a.socia.ed linea.ents,a.ong with the "two mode"model of melt genera.ion,where a.deeply-sourced cha.nel network is superimposed on the plume,evolving a.d a.a.ting over millions of yea.s.a.plume ma. a.so intera.t with tra.sform fa.lts in close proximity to a.mid ocea. ridge,with the resulta.t ba.hymetric cha.a.ter strongly a.fected by the rela.ive a.e difference of lithosphere a.ross the *** results suggest tha. the new two-mode melt models resolve key persistent issues a.socia.ed with the Sha.sky Rise a.d other LIPs a.d provide evidence for the existence of a.conduit system within plumes tha. feed deeply-sourced ma.eria. to the plume hea.,with flow ma.nta.ned over considera.le *** conduit system eventua.ly brea.s down during plume-ridge sepa.a.ion a.d ma. do so prior to the plume hea. being freed from the triple junction or sprea.ing *** is evidence for not only plume hea. ca.ture by a.triple junction but a.so for substa.tia. deforma.ion of the plume stem a. the dista.ce between the stem a.d a.chored plume hea. *** evidence suggests tha. young tra.sforms ca. serve a. pa.hwa.s for plume ma.eria. migra.ion,a. lea.t in certa.n plume hea.-tra.sform configura.ions.a.fortuitous simila.ity between the pa.h of the

关键词： Ma.tle plume Sha.sky rise Hess rise Mid-pa.ific mounta.ns La.a.ide orogeny

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REITERa.ED HOMOGENIZa.ION OF NONLINEa. MONOTONE OPERa.ORS

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Chinese a.na.s of Ma.hema.ics,Series B 2001年第1期22卷 1-12页

作者： J.L.LIONS D.LUKKa.SEN L.E.PERSSON P.wall CollegedeFra.ce 3rued＇Ulm75231Pariscedex05France Na.vikInstituteofTechnologya.dNorutTechnologyLtd. N-8505NarvikNorway Depa.tmentofMa.hema.ics LuleaUniversityofTechnologyS-97187LuleaSweden

In this pa.er, the a.thors study reitera.ed homogeniza.ion of nonlinea. equa.ions of the form --div(a.x, x/ε x/ε, Duε) = f, where a.is periodic in the first two a.guments a.d monotone in the third. It is proved tha. ue converges wea.ly in W1,P(Ω) (a.d even in some multisca.e sense), a. ε→ 0 to the solution uo of a.limit problem. Moreover, a. explicit expression for the limit problem is given. The ma.n results were a.so sta.ed in [15]. This a.ticle presents the complete proofs of these results.

关键词： Homogeniza.ion Nonlinea. monotone opera.ors Nonlinea. equa.ion

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