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绝经后骨质疏松性胸腰椎骨折患者PVP后再次骨折风险的列线图模型构建及验证

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中国性科学 2024年第5期33卷 105-110页

作者：缪世昌张梦戚文元胡飞江苏省江阴市中医院骨科江苏无锡214400 江南大学附属医院骨科江苏无锡214000

目的构建列线图模型分析绝经后骨质疏松性胸腰椎骨折(OTF)患者经皮椎体成形术(PVP)后再次骨折的影响因素。方法采用回顾性病例对照研究纳入2018年1月至2022年9月于江苏省江阴市中医院接受PVP手术治疗的690例绝经后OTF患者作为研究对象,... 详细信息

目的构建列线图模型分析绝经后骨质疏松性胸腰椎骨折(OTF)患者经皮椎体成形术(PVP)后再次骨折的影响因素。方法采用回顾性病例对照研究纳入2018年1月至2022年9月于江苏省江阴市中医院接受PVP手术治疗的690例绝经后OTF患者作为研究对象,以简单随机抽样法按照7∶3比例分为建模组(n=483)与验证组(n=207)。采用单因素分析建模组患者PVP后再次骨折的独立危险因素并构建列线图,以验证组数据对列线图模型进行外部验证。结果经Logistic回归分析显示,年龄(OR=1.173,95%CI:1.114~1.236)、骨密度T值(OR=0.436,95%CI:0.293~0.647)、多椎体手术(OR=2.146,95%CI:1.332~3.458)、骨水泥渗漏(OR=2.233,95%CI:1.204~4.141)、骨水泥弥散程度(OR=2.600,95%CI:1.505~4.492)、术后规律抗骨质疏松治疗(OR=1.788,95%CI:1.069~2.993)是PVP后再次骨折的影响因素(P<0.05)。基于以上影响因素建立列线图风险模型,绘制受试者工作特征(ROC)曲线,曲线下面积(AUC)为0.782(95%CI:0.711~0.853,P<0.001),模型预测效能良好。结论根据绝经后OTF患者PVP后再次骨折的危险因素构建的列线图模型能有效预测PVP后再次骨折的风险。

关键词：骨质疏松性胸腰椎骨折绝经后女性经皮椎体成形术再次骨折列线图

朱砂七的药理作用及其在动物医学方面的应用研究进展

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动物医学进展 2024年第10期45卷 90-95页

作者：杜雨佳赵浩淼裴鹏飞柳潞妍卿素珠西北农林科技大学动物医学院陕西杨陵712100

朱砂七为我国的一种传统中药,又名红药子、雄黄连、血三七等。朱砂七在陕西太白山一带具有悠久的药用历史,其味苦性凉,具有清热解毒、健脾益胃、收敛固涩、凉血活血、止血止泻等多种功效,可用于治疗各类炎症、泌尿系统感染、出血症等。... 详细信息

朱砂七为我国的一种传统中药,又名红药子、雄黄连、血三七等。朱砂七在陕西太白山一带具有悠久的药用历史,其味苦性凉,具有清热解毒、健脾益胃、收敛固涩、凉血活血、止血止泻等多种功效,可用于治疗各类炎症、泌尿系统感染、出血症等。近年研究表明,朱砂七具有抑菌、抗氧化、抗肿瘤、抗病毒等作用,针对其活性成分药理作用研究较多的有多糖、蒽醌类和总鞣质等。在畜禽疫病防治方面,以朱砂七多糖的相关研究较为突出,并已展示出其应用潜力。论文主要针对朱砂七活性成分的药理作用及其在动物医学方面的应用研究进展进行综述,旨在为其开发应用提供参考。

关键词：朱砂七多糖总蒽醌药理作用动物医学

Numerical method of static aeroelastic correction and jig-shape design for large airliners

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Science China(Technological Sciences) 2012年第9期55卷 2447-2452页

作者： HUANG Wei LU ZhiLiang GUO TongQing XUE fei ZHANG miao Department of Aerodynamics Nanjing University of Aeronautics and AstronauticsNanjing 210016China Shanghai Aircraft Design and Research Institute Shanghai 200232China

In this paper,a coupled CFD-CSD method based on N-S equations is described for static aeroelastic correction and jig-shape design of large *** wing structural flexibility matrix is analyzed by a finite element method with a double-beam *** viscous multi-block structured grid is used in aerodynamic *** matrix interpolation is fulfilled by use of a surface spline *** load distributions on wing surface are evaluated by solving N-S equations with a parallel algorithm.A flexibility approach is employed to calculate the structural *** successive iterations between steady aerodynamic forces and structural deformations,a coupled CFD-CSD method is achieved for the static aeroelastic correction and jig-shape design of a large *** present method is applied to the static aeroelastic analysis and jig-shape design for a typical large airliner with engine nacelle and *** numerical results indicate that calculations of static aeroelastic correction should employ tightly coupled CFD-CSD iterations,and that on a given cruise shape only one round of iterative design is needed to obtain the jig-shape meeting design requirements.

关键词： N-S equations large airliner static aeroelasticity flexibility matrix jig-shape

基于Transformer的U型低照度图像增强算法

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建模与仿真 2024年第3期13卷 3491-3506页

作者：缪天恒梁艳王飞丁德锐上海理工大学光电信息与计算机工程学院上海上海理工大学管理学院上海

针对非均匀光照环境下照度自适应算法的固有缺陷以及基于CNN的图像增强模型固有的卷积运算导致的感受野受限、无法建立长距离的全局依赖等问题,本文提出一种融合CA-Transformer模块和全局注意力融合模块的U型网络RT-UNet。本研究设计了... 详细信息

针对非均匀光照环境下照度自适应算法的固有缺陷以及基于CNN的图像增强模型固有的卷积运算导致的感受野受限、无法建立长距离的全局依赖等问题,本文提出一种融合CA-Transformer模块和全局注意力融合模块的U型网络RT-UNet。本研究设计了基于轴向多头自注意力机制的CA-Transformer模块作为特征提取和重建的基础模块。该模块在兼顾CNN与Transformer结构优点的同时极大地减少了计算复杂度。进而,为了建立不同尺度,不同分辨率特征图之间的信息交互与融合,搭建了全局注意力融合模块来替代之前的残差连接,帮助网络关注到更感兴趣的区域,方便其学习到更有用,更精细的特征。实验结果表明,本算法在主客观评价指标上相比于近几年一些主流图像增强算法均具有很强的竞争力。

关键词：低照度增强 Transformer 注意力机制特征融合

Inverse Estimation of Transient Heat Flux to Slab Surface

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Journal of Iron and Steel Research International 2012年第11期19卷 13-18页

作者： CUI miao YANG Kai LIU Yun-fei GAO Xiao-wei State Key Laboratory of Structural Analysis for Industrial Equipment Dalian University of TechnologyDalian 116024 Liaoning China

The transient heat flux was calculated using a model for inverse heat conduction problems based on temper- ature measurements. The unknown heat flux was taken as an optimization variable and solved by minimizing the differences between the calculated temperatures and the measured ones. Several examples were given to show the ef- fectiveness and the accuracy of the inverse algorithm in estimating the transient heat flux to a slab surface. The re sults show that the inverse approach can be applied in the steel industry or in other areas where the target of investi- gation is inaccessible to direct measurements or difficult to be directly modeled.

关键词： transient heat flux inverse estimation reheating furnace least-square method sensitivity analysis

Better tillage selection before ridge–furrow film mulch can facilitate root proliferation, and increase nitrogen accumulation,translocation and grain yield of maize in a semiarid area

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Journal of Integrative Agriculture 2023年第6期22卷 1658-1670页

作者： ZHANG miao-miao DANG pen.-fei LIYu-ze QIN Xiao-liang Kadambot H.M.SIDDIQUE College of Agronomy/Key Laboratory of Crop Physio-ecology and Tillage Science in Northwestern Loess Plateau Northwest A&F UniversityYangling 712100P.R.China The UWA Institute of Agriculture and School of Agriculture&Environment The University of Western AustraliaPerth WA 6001Australia

Plastic film mulch systems are used widely in arid areas, and the associated tillage measures affect soil properties, root and crop growth, and nutrient uptake. However, much debate surrounds the most suitable tillage method for plastic film mulch systems. We conducted a two-year field experiment to explore the impact of three tillage treatments-rotary tillage before ridge–furrow plastic film mulch(MR), no-tillage before ridge–furrow plastic film mulch(MZ), and plow tillage before ridge–furrow plastic film mulch(MP)-on soil total nitrogen, available nitrogen, root stratification structure,nitrogen transfer and utilization, and maize yield. The results showed that MP had better soil quality than either MR or MZ over 2019 and 2020, with higher nitrate-nitrogen and total nitrogen in the 0–40 cm soil layer. MP improved the soil physicochemical properties more than the other treatments, producing significantly higher root numbers and root biomass for the aerial and underground nodal roots than MR and MZ. At harvest, MP had the highest root biomass density,root length density, and root surface area density in the different soil layers(0–20, 20–40, and 0–40 cm). Significant correlations occurred between root biomass and aboveground nitrogen accumulation during maize growth. During grain filling, MP had the greatest nitrogen transfer amount, significantly increasing root and aboveground nitrogen transfer by 19.63–45.82% and 11.15–24.56%, respectively, relative to the other treatments. MP significantly produced 1.36–26.73%higher grain yields and a higher grain crude protein content at harvest than MR and MZ. MP also had higher values for the nitrogen harvest index, nitrogen uptake efficiency, and partial factor productivity of nitrogen fertilizer than MR and *** conclusion, plow tillage combined with a ridge–furrow plastic film mulch system facilitated maize root development and improved nitrogen utilization, thereby increasing maize yield more than the other treatments.

关键词： maize tillage plastic film mulch root nitrogen transfer

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多头双向螺旋面的加工方案研究

煤矿机械 2024年第10期45卷 109-113页

作者：李菲苗晓鹏张佑林安阳工学院机械工程学院河南安阳455000 厦门工学院福建厦门361021

在介绍活齿端面谐波齿轮的传动原理及多头双向螺旋面含义的基础上,提出了2种加工多头双向螺旋面的方案,并进行了分析、比较。方案一:先采用三维建模软件(如NX等)对具有不同参数的多头双向螺旋面的零件进行建模,再利用数控立式加工中心... 详细信息

在介绍活齿端面谐波齿轮的传动原理及多头双向螺旋面含义的基础上,提出了2种加工多头双向螺旋面的方案,并进行了分析、比较。方案一:先采用三维建模软件(如NX等)对具有不同参数的多头双向螺旋面的零件进行建模,再利用数控立式加工中心进行加工;方案二:利用数控电火花线切割机床与数控回转工作台互相配合,按照多头双向螺旋面形成的原理进行加工。

关键词：活齿端面谐波齿轮齿面多头双向螺旋面加工方案

DAO to HANOI via DeSci: AI Paradigm Shifts from AlphaGo to ChatGPT

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IEEE/CAA Journal of Automatica Sinica 2023年第4期10卷 877-897页

作者： Qinghai miao Wenbo Zheng Yisheng Lv Min Huang Wenwen Ding fei-Yue Wang School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China School of Computer Science and Artificial Intelligence Wuhan University of TechnologyWuhan 430070China Institute of Automation Chinese Academy of SciencesBeijing 100190China Institute of System Engineering Macao University of Science and TechnologyMacaoChina

From AlphaGo to ChatGPT,the field of AI has launched a series of remarkable achievements in recent ***,comparing,and summarizing these achievements at the paradigm level is important for future AI innovation,but has not received sufficient *** this paper,we give an overview and perspective on machine learning ***,we propose a paradigm taxonomy with three levels and seven dimensions from a knowledge ***,we give an overview on three basic and twelve extended learning paradigms,such as Ensemble Learning,Transfer Learning,etc.,with figures in unified *** further analyze three advanced paradigms,i.e.,AlphaGo,AlphaFold and ***,to enable more efficient and effective scientific discovery,we propose to build a new ecosystem that drives AI paradigm shifts through the decentralized science(DeSci)movement based on decentralized autonomous organization(DAO).To this end,we design the Hanoi framework,which integrates human factors,parallel intelligence based on a combination of artificial systems and the natural world,and the DAO to inspire AI innovations.

关键词： ChatGPT decentralized science(DeSci) decentralized autonomous organization(DAO) machine learning paradigm shift

Increased CAP37 Expression in Stable Chronic Obstructive Pulmonary Disease

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Current Medical Science 2022年第5期42卷 949-957页

作者： Jin-qing CHEN Yi-fei DUAN Jian-miao WANG Department of Respiratory and Critical Care Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Objective Cationic antimicrobial protein of 37 kDa(CAP37),a neutrophil-derived protein originally identified for its antimicrobial activity,is now known to have many regulatory effects on host ***,its role in the pathogenesis of chronic obstructive pulmonary disease(COPD)has not been *** therefore investigated the expression of CAP37 in COPD and its effects on airway structural cells,including bronchial epithelial cells,smooth muscle cells,and *** CAP37 was detected in the lung tissue,sputum,and plasma of COPD patients and the control subjects,as well as in the neutrophils stimulated by cigarette smoke extract(CSE).BEAS-2B cells,human bronchial smooth muscle cells(HBSMCs),and MRC-5 cells were treated with CAP37 or an anti-CAP37 antibody plus ***(IL)-6 and IL-8 were detected in the BEAS-2B *** cell proliferation was analyzed in the *** were also detected in the MRC-5 *** The expression of CAP37 was increased in the lung tissue and sputum supernatant of the COPD patients compared with the control *** sputum supernatant CAP37 levels were inversely correlated with the forced expiratory volume in the first second percentage predicted in ***37 was induced by CSE stimulation in the peripheral blood neutrophils from healthy ***37 induced expression of IL-6 and IL-8 in BEAS-2B cells,and collagen expression of lung fibroblasts(MRC-5 cells).However,CAP37 did not significantly alter the proliferation of the *** Our findings indicated that neutrophil-derived CAP37 may be involved in airway inflammation and fibrosis in COPD via affecting the bronchial epithelial cells,and fibroblasts,thus suggesting a possible role of CAP37 in the development and progression of COPD.

关键词： cationic antimicrobial protein of 37 kDa chronic obstructive pulmonary disease fibrosis inflammation neutrophil