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Pectin Oligosaccharides Glycosylation Modification Reduced the Sensitization of Shrimp Tropomyosin by Regulating Cytokines Expression and Th1/Th2 Immune Balance

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Food Science and Human Wellness 2024年

作者： Mengya Zhao chunyu Wu Jing Liu Xinian Li Zhenpeng Gao Xin Yang Di Liu Fangyu Long College of Food Science and Engineering， Northwest A&F University Institute of Animal Husbandry and Veterinary Medicine， Guizhou Academy of Agricultural Sciences College of Animal Science and Technology， Northwest A&F University

Tropomyosin (TM) is the predominant allergenic protein in shrimp， which has induced IgE-mediated food allergy reactions. In this study， Lit v 1 was purified from Penaeus vannamei muscles， which were glycosylated by pectic oligosaccharides. The results showed that Di-Galacturonic acid (DGA) and galacturonic acid (GA) induced the unfolding of the primary protein structure of TM， and changed alpha-helical structure， and IgE binding capacity. In addition， compared with TM-sensitized BALB/c mice， galacturonic acid-modified TM (GA-TM) and Di-Galacturonic acid-modified TM (DGA-TM) were insufficient to stimulate sensitization， and significantly reduced the hypersecretion of IgE， IgG1， HIS， and IL-4， up-regulated IgG2a and IFN-γ levels to improve imbalanced Th1/Th2， Treg/Th17 immunity， and promoted mRNA expression of tight junction proteins. Together， this study confirmed that glycosylation modification alleviated sensitization by altering TM structure， reducing IgE binding allergic inflammatory response， and regulating cytokine immune balance. Overall， these results indicated that glycosylation modification was a promising method for decreasing the allergenic reactivity of allergic proteins.

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政府创新危机管理体制的若干要点——日本阪神大地震个案分析

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重庆大学学报（社会科学版） 2005年第3期11卷 42-45页

作者：李忠荣淳于淼泠重庆大学贸易与行政学院重庆400030

1995年1月发生在日本大阪、神户一带的“阪神大地震”是日本自1923年关东大地震以来受灾损失最惨重的一次。除了7级大地震本身的超强破坏性以外,日本政府在这次公共危机管理中的严重失误则是造成震灾恶性后果的人为原因。日本政府在阪... 详细信息

1995年1月发生在日本大阪、神户一带的“阪神大地震”是日本自1923年关东大地震以来受灾损失最惨重的一次。除了7级大地震本身的超强破坏性以外,日本政府在这次公共危机管理中的严重失误则是造成震灾恶性后果的人为原因。日本政府在阪神大地震中所表现出来的危机管理观念及其行为方式等充分说明科学的危机防范意识、权变的危机管理机制、通常快捷的信息传递渠道、协调的危机管理体制是创新政府危机管理体制的关键要素。

关键词：政府公共危机管理体制创新日本阪神大地震

Development of a rapid and efficient system for CR genes identification based on hairy root transformation in Brassicaceae

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Horticultural Plant Journal 2024年第4期10卷 1049-1060页

作者： Wenlin Yu Lu Yang Yuanyuan Xiang Rongde Li Xueqing Zhou Longcai Gan Xianyu Xiang Yunyun Zhang Lei Yuan Yanqing Luo Genze Li Youning Wang Yinhua Chen Peng Chen chunyu Zhang National Key Laboratory of Crop Genetic Improvement and College of Plant Science and Technology Huazhong Agricultural UniversityWuhanHubei 430070China National Key Laboratory for Tropical Crop Breeding Sanya Nanfan Research InstituteHainan UniversitySanyaHainan 572025China National Agro-Tech Extension and Service Center Beijing 100125China Industrial Crops Research Institute Yunnan Academy of Agricultural SciencesKunmingYunnan 650221China College ofAgronomy NorthwestA&F UniversityYanglingShaanxi712100China

Many economically important crops and vegetables belonging to the cruciferous family are heavily endangered by clubroot disease caused by Plasmodiophora brassicae *** of clubroot resistant cultivars based on mapping and cloning of resistant genes is commonly regarded as the most cost-effective and efficient way to fight against this *** traditional way of R gene functional validation requires stable transformation that is both time-and *** this study,a rapid and efficient hairy-root transgenic protocol mediated by Agrobacterium rhizogenes was *** transformation positive rate was over 80%in Brassica napus showed by GUS reporter gene and this transformation only took 1/6 of the time compared with stable *** system was applicable to different *** varieties and other cruciferous crops including Brassica rapa and Brassica *** particular,two known CR genes,CRA3.7.1 and CRA8.2.4 were used respectively,as example to show that the system works well for CR gene study combined with subsequent *** infection in *** importantly,it works both in over-expression that led to disease resistance,as well as in RNAi which led to disease susceptible ***,this system can be used in batch-wise identification of CR genes,and also offered the possibility of manipulating key genes within the *** genome that could improve our knowledge on host-pathogen interaction.

关键词： Brassicaceae Agrobacterium rhizogenes Hairy root transformation Clubroot Gene function

X80管线钢激光-MAG复合横焊打底焊工艺

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机械制造文摘（焊接分册） 2022年第2期 24-29页

作者：苗春雨焦向东朱加雷李京洋王凯北京石油化工学院北京102617 北京化工大学北京100029 燕山石化高科技术有限责任公司北京100000

以X80管线钢为研究对象,借助拉伸、弯曲、硬度等力学性能测试评价激光-MAG复合横焊打底焊接头的力学性能。研究了光丝间距对激光-MAG复合横焊焊缝成形的影响。结果表明,光丝间距为2 mm时获得的焊缝对称性最好,复合热源耦合性能最好,熔... 详细信息

以X80管线钢为研究对象,借助拉伸、弯曲、硬度等力学性能测试评价激光-MAG复合横焊打底焊接头的力学性能。研究了光丝间距对激光-MAG复合横焊焊缝成形的影响。结果表明,光丝间距为2 mm时获得的焊缝对称性最好,复合热源耦合性能最好,熔池下淌倾向最小。X80管线钢焊接接头的拉伸、弯曲和显微硬度试验测试结果满足API 5L标准要求。

关键词：激光-MAG复合横焊光丝间距复合热源 X80管线钢

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抵御虫洞攻击的无线传感器网安全定位算法

传感技术学报 2016年第12期29卷 1882-1887页

作者：陈立建金洪波毛科技苗春雨邬锦彬陈庆章浙江广播电视大学萧山学院杭州311201 浙江工业大学计算机科学与技术学院杭州310023

节点定位技术是无线传感器网络的支撑技术之一,节点位置信息是很多基于无线传感器网络的应用的基础。无线传感器网络是一个动态的网络,每隔一段时间需要进行重新定位,并且在重定位过程中易受到攻击节点攻击。针对无线传感器网络中无需... 详细信息

节点定位技术是无线传感器网络的支撑技术之一,节点位置信息是很多基于无线传感器网络的应用的基础。无线传感器网络是一个动态的网络,每隔一段时间需要进行重新定位,并且在重定位过程中易受到攻击节点攻击。针对无线传感器网络中无需测距的定位技术,分析虫洞攻击对DV-Hop定位的影响,提出了一种基于信誉模型的抵御虫洞攻击的分布式轻量级DV-Hop安全定位算法TMDV-Hop(Trust-Model-based DV-Hop Localization Against Wormhole Attack)。仿真表明,在无需额外硬件辅助下,TMDV-Hop算法能有效降低虫洞攻击对定位过程的影响,验证了该算法的有效性。

关键词：无线传感器网络安全定位 DV-Hop 虫洞攻击信誉模型

A novel nondestructive detection approach for seed cotton lint percentage using deep learning

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Journal of Cotton Research 2024年第2期7卷 148-162页

作者： GENG Lijie YAN Pengji JI Zhikun SONG chunyu SONG Shuaifei ZHANG Ruiliang ZHANG Zhifeng ZHAI Yusheng JIANG Liying YANG Kun School of Electronic and Information Henan Key Laboratory of Magnetoelectronic Information Functional MaterialsZhengzhou University of Light IndustryZhengzhou 450002HenanChina

Background The lint percentage of seed cotton is one of the most important parameters for evaluating seed cotton quality and affects its *** traditional measuring method of lint percentage is labor-intensive and time-consuming;thus,an efficient and accurate measurement method is *** recent years,classification-based deep learning and computer vision have shown promise in solving various classification *** In this study,we propose a new approach for detecting the lint percentage using MobileNetV2 and transfer *** model is deployed on a lint percentage detection instrument,which can rapidly and accurately determine the lint percentage of seed *** evaluated the performance of the proposed approach using a dataset comprising 66924 seed cotton images from different regions of *** results of the experiments showed that the model with transfer learning achieved an average classification accuracy of 98.43%,with an average precision of 94.97%,an average recall of 95.26%,and an average F1-score of 95.20%.Furthermore,the proposed classification model achieved an average accuracy of 97.22%in calculating the lint percentage,showing no significant difference from the performance of experts(independent-sample t-test,t=0.019,P=0.860).Conclusion This study demonstrated the effectiveness of the MobileNetV2 model and transfer learning in calculating the lint percentage of seed *** proposed approach is a promising alternative to traditional methods,providing a rapid and accurate solution for the industry.

关键词： Neural network MobileNetV2 Nondestructive detection Smart agriculture Seed cotton lint percentage

Al-driven analysis establishes the single base substitution signatures as personalized prognostic predictors for five-year survival of gastric cancer

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Genes & Diseases 2024年第4期11卷 73-76页

作者： Zhenzhang Li Lingqing Xu Wen Luo Shaoan Zhangg chunyu Hou Xiaohong Xu ,Xubei Peng E.Shiju Janak L.Pathak Shizhen Zhang Jiawei Liu Linhai Li Yang Li School of Biomedical Engineering The Sixth Affiliated HospitalGuangzhou Medical UniversityGuangzhouGuangdong 511436China College of Mathematics and Systems Science Guangdong Polytechnic Normal UniversityGuangzhouGuangdong 510665China The Second Affiliated Hospital Guangzhou Medical UniversityGuangzhouGuangdong 510260China Center for Learning Sciences and Technologies The Chinese University of Hong KongShatinNew Territories 999077China Affiliated Stomatology Hospital of Guangzhou Medical University Guangzhou Medical UniversityGuangzhouGuangdong 510182China International School of Photonics Cochin University of Science and TechnologyKochiKerala 682022India

Al-driven genetic engineering,as a burgeoning diagnostic tool,can offer predictive information on the five-year survival rate(FYSR)in the setup of a prognostic therapeutic *** approach provides the individuality and accuracy of prognosis for FYSR of gastric cancer(GC).Unlike traditional neoplasm staging criteria,our technique ensures accuracy and individuality without relying on statistical data and empirical study.

关键词： cancer gastric prognosis

Mitigating kinetic hindrance of single-crystal Ni-rich cathodes through morphology modulation,nickel reduction,and lithium vacancy generation achieved by terbium doping

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Journal of Energy Chemistry 2024年第10期97卷 566-574,I0012页

作者： Jiyuan Jian Shuang Lin Guokang Han Xianglian Zhan Yinghui Shan Rang Xiao Ziwei Liu Dandan Sun Xin Zhang Qingjie Zhou Geping Yin Hua Huo Yulin Ma Pengjian Zuo Xinqun Cheng chunyu Du State Key Laboratory of Space Power-sources School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001HeilongjiangChina Zibo Torch Energy Co.Ltd Zibo 255051ShandongChina

Single crystallization has proven to be effective in enhancing the capacity and stability of Ni-rich LiNi_(1-x-y)Co_(x)Mn_(y)O_(2)(SNCM)cathode materials,particularly at high cut-off ***,the synthesis of high-quality single-crystal particles remains challenging because of severe particle agglomeration and irregular ***,the limited kinetics of solid-phase Li^(+)diffusion pose a significant concern because of the extended diffusion path in large single-crystal *** address these challenges,we developed a Tb-doped single-crystal LiNi_(0.83)Co_(0.11)Mn_(0.06)O_(2)(SNCM-Tb)cathode material using a straightforward mixed molten salt sintering *** Tb-doped Ni-rich single crystals presented a quasi-spherical morphology,which is markedly different from those reported in previous ***^(4+)oping significantly enhanced the dynamic transport of Li^(+)ions in the layered oxide phase by reducing the Ni valence state and creating Li vacancies.A SNCM-Tb material with 1 at%Tb doping shows a Li^(+)diffusion coefficient up to more than 9 times higher than pristine SNCM in the non-diluted *** situ X-ray diffraction analysis demonstrated a significantly facilitated H1-H2-H3 phase transition in the SNCM-Tb materials,thereby enhancing their rate capacity and structural ***-Tb exhibited a reversible capacity of 186.9 mA h g^(-1)at 5 C,retaining 94.6%capacity after 100 cycles at 0.5 C under a 4,5 V *** study elucidates the Tb^(4+)doping mechanisms and proposes a scalable method for enhancing the performance of single-crystal Ni-rich NCM materials.

关键词： Lithium-ion batteries Ni-rich layered oxides Single crystals Tb^(4+) doping Li^(+) diffusion kinetics

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无线传感器网络中的节点位置验证方法

传感技术学报 2015年第6期28卷 850-857页

作者：毛科技金洪波苗春雨邬锦彬雷艳静陈庆章浙江工业大学计算机科学与技术学院杭州310023 浙江师范大学行知学院杭州321004

节点位置信息是感测数据的重要上下文信息,节点自定位技术是无线传感器网络的支撑技术之一。在基于信标节点的定位技术中,信标节点位置的可靠性是影响网络服务质量的关键因素。针对信标节点位置漂移和恶意信标节点引起定位精度下降的问... 详细信息

节点位置信息是感测数据的重要上下文信息,节点自定位技术是无线传感器网络的支撑技术之一。在基于信标节点的定位技术中,信标节点位置的可靠性是影响网络服务质量的关键因素。针对信标节点位置漂移和恶意信标节点引起定位精度下降的问题,提出了一种基于信誉模型的分布式轻量级节点位置验证方法(Reputationbased Location Verification,RLV),通过建立无线传感器网络中的节点位置信誉模型来识别网络中的不可靠信标节点。仿真结果表明信誉模型能够较好的反映节点的定位精度,RLV算法可以探测出95%以上的不可靠信标节点。

关键词：无线传感器网络可信定位信誉模型信标漂移恶意锚节点