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饲料中大豆异黄酮和大豆皂甙对牙鲆肝脏和肠道蛋白质消化酶活性和基因表达的影响

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中国海洋大学学报（自然科学版） 2011年第12期41卷 40-45页

作者：米海峰徐玮麦康森张文兵陈伟吴成龙中国海洋大学海水养殖教育部重点实验室山东青岛266003

以鱼粉为蛋白源,小麦粉为糖源,鱼油为脂肪源配制基础饲料,分别添加不同浓度梯度(0.1%、0.4%和0.8%)的大豆异黄酮和大豆皂甙。以不添加大豆异黄酮和大豆皂甙的基础饲料作为对照组,共制成7种等氮(粗蛋白49.1%)、等能(总能20.1kJ/g)的实验... 详细信息

以鱼粉为蛋白源,小麦粉为糖源,鱼油为脂肪源配制基础饲料,分别添加不同浓度梯度(0.1%、0.4%和0.8%)的大豆异黄酮和大豆皂甙。以不添加大豆异黄酮和大豆皂甙的基础饲料作为对照组,共制成7种等氮(粗蛋白49.1%)、等能(总能20.1kJ/g)的实验饲料。在循环水系统中养殖初始体质量为(2.58±0.01)g的牙鲆(Paralichthys olivaceus)幼鱼,8周后观测牙鲆肝脏和肠道蛋白质消化酶活性和基因表达的影响。结果表明,牙鲆肠道胰蛋白酶的活性不受饲料中大豆异黄酮的显著影响(P>0.05),却随大豆皂甙添加量的升高而显著下降(P<0.05)。肠道糜蛋白酶的活性在饲料中大豆异黄酮添加量为0.1%时取得最大值(37.3±5.9)U/mg,显著高于其它处理组。饲料中添加不同水平的大豆异黄酮对肝脏中胰蛋白酶-1和糜蛋白酶-1基因表达量有显著(P<0.05)的影响,而添加大豆皂甙却对这些基因表达量的影响不显著。由此可见,大豆异黄酮直接作用于基因表达和酶活两个水平,而大豆皂甙只在酶活水平发挥显著的作用。同时,大豆异黄酮对牙鲆饲料利用率影响的双重性依赖于剂量的大小,其中的作用机制有待于进一步研究。

关键词：牙鲆饲料大豆异黄酮大豆皂甙蛋白质消化酶

Mspl Polymorphisms in the 3rd Intron of the Swine POUIFI （Pit-1） Gene and Its Correlation with Growth Performance

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Mspl Polymorphisms in the 3rd Intron of the Swine POUIFI （P...

植物精油对动物的促生长作用及作用机制研究进展

全国首届动物生物技术学术研讨会

作者： SONG Cheng-yi, TENG Yong, GAO Bo, mi hai-feng, JIN Rong-bin MAO Jiu-de (College of Animal Science and Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China Department of Animal Science, University of missouri-Columbia, Columbia, MO 65211, USA )

＜正＞ The transcription factor pituitary-1 （Pit-1, renamed as POU1F1） is a homeodomain-containing protein expressed mainly in the pituitary. POU1F1 stimulates the expression of growth hormone, prolactin, and thyroid-stimulating hormone genes. Therefore, it plays an important role in regulating animal growth and POU1F1 is also a good genetic marker for growth performance in livestock animals. The objective of the present study was to compare Mspl polymorphisms in the 3rd intron of the porcine POU1F1 gene among two meat-type pigs （Landrace and Duroc）, two fat-type pigs （Chinese Meishan and Jiangquhai）, and a miniature pig （Chinese Xiangzhu） by using the PCR-RFLP technique, and to determine the correlation between gene expression and growth performance in commercial pig population. A monomorphic fragment of 0.42 kb and two polymorphic fragments of 1.68 kb （C allele） and 0.85/0.83 kb （D allele） were observed. There was a significant difference in the genotypic and allelic frequencies at Mspl polymorphic restriction site among the five pig breeds （P＜0.01）. The frequency of allele C was highest in Jiangquhai （85%） and Meishan （90%）, intermediate in Xiangzhu （33%） and low in Landrace （2%） and Duroc （3%）. The general linear model analyses revealed that the pigs with genotype DD had higher 45-day, 70-day, and 180-day body weight （P＜0.05） and higher average daily gain （P＜0.01）.

关键词： POUIF Polymorphism Growth traits

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安徽农业科学 2015年第32期43卷 85-88,92页

作者：张高明胡毅米海峰湖南农业大学动物科学技术学院湖南长沙410128

伴随着抗生素滥用导致的细菌抗药性问题的出现,各种抗生素替代品的开发与利用取得了一定的进展。植物精油作为一种健康、环保并具有多种功效的新型饲料添加剂在畜牧生产中已经越来越多地被重视和认可。对植物精油的定义、来源、抗菌作... 详细信息

伴随着抗生素滥用导致的细菌抗药性问题的出现,各种抗生素替代品的开发与利用取得了一定的进展。植物精油作为一种健康、环保并具有多种功效的新型饲料添加剂在畜牧生产中已经越来越多地被重视和认可。对植物精油的定义、来源、抗菌作用及其在动物生产中的应用以及存在问题进行了综述,旨为植物精油在畜牧生产中的合理应用提供理论依据。

关键词：植物精油抑菌作用生产性能应用

Boosting Photocatalytic Performance of Cu-Mn Co-doped CeO_(2) Nanoparticles for Tetracycline Degradation

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 42-48页

作者： XU Rongqi mi Jianxin WANG Shulin XU Man ZHU Li BAI Lei TANG Dandan LEI Yu Engineering Research Center of Environmental Materials and Membrane Technology of Hubei Province School of Materials Science and EngineeringWuhan Institute of TechnologyWuhan 430205China Shaanxi Coal Chemical Industry Technology Research Institute Co. Ltd.Xi’an 710100China

Cu-Mn co-doped CeO_(2) photocatalyst was successfully synthesized by the sol-gel method to assess its capability in degrading *** and TEM results showed that Cu and Mn were successfully co-doped into CeO_(2) without forming heterostructure,XPS and photoelectrochemical results revealed that Mn ions doping amplified the generation of photo-induced charge carriers,while Cu ions doping significantly facilitated the interfacial charge transfer ***,the optimized Cu3Mn2CeO_(2) nanoparticles exhibited the highest TC removal efficiency,achieved a rate of 78.18%and maintained a stable cycling performance.

关键词： photocatalyst co-doped charge separation water treatment

Highly mass activity electrocatalysts with ultralow Pt loading on carbon black for hydrogen evolution reaction

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International Journal of minerals,Metallurgy and Materials 2025年第1期32卷 182-190页

作者： Shaorou Ke Yajing Zhao Xin min Yanghong Li Ruiyu mi Yangai Liu Xiaowen Wu minghao Fang Zhaohui Huang Engineering Research Center of ministry of Education for Geological Carbon Storage and Low Carbon Utilization of Resources Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid WastersNational Laboratory of Mineral MaterialsSchool of Materials Science and TechnologyChina University of Geosciences(Beijing)Beijing 100083China

Pt-based nanocatalysts offer excellent prospects for various ***,the low loading of Pt with excellent performance for efficient and stable nanocatalysts still presents a considerable *** this study,nanocatalysts with ultralow Pt content,excellent performance,and carbon black as support were prepared through in-situ ***~2-nm particles uniformly and stably dispersed on carbon black because of the strong s-p-d orbital hybridizations between carbon black and Pt,which suppressed the agglomeration of Pt *** unique structure is beneficial for the hydrogen evolution *** catalysts exhibited remarkable catalytic activity for hydrogen evolution reaction,exhibiting a potential of 100 mV at 100 mA·cm^(-2),which is comparable to those of commercial Pt/C *** activity(1.61 A/mg)was four times that of a commercial Pt/C catalyst(0.37 A/mg).The ultralow Pt loading(6.84wt%)paves the way for the development of next-generation electrocatalysts.

关键词： hydrogen evolution reaction ultralow platinum in-situ synthesis ultrasound

Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong Xing Xinzhu Liu Xiandeng Li mi Li Xian Wu Xiaohui Huang Ajing Xu Yan Liu Jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

综合理解韧性治理视角下的城市社区洪涝灾害韧性及分析框架

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灾害学 2025年第1期40卷 8-15页

作者：孔锋米胤瑜王一飞中国农业大学人文与发展学院北京100083 北京市科学技术协会防灾减灾专业智库基地北京100089 清华大学应急管理研究基地北京100084 中国气象局气象干部培训学院北京100081

气候变化背景下频发重发的洪涝灾害是人类社会可持续发展面临的重大挑战之一。该文首先从洪涝灾害治理的转变出发,深入探讨了从传统的洪涝风险管理向洪涝风险治理转变的深层含义,并概述了韧性城市发展的关键特征。接着,文章对韧性概念... 详细信息

气候变化背景下频发重发的洪涝灾害是人类社会可持续发展面临的重大挑战之一。该文首先从洪涝灾害治理的转变出发,深入探讨了从传统的洪涝风险管理向洪涝风险治理转变的深层含义,并概述了韧性城市发展的关键特征。接着,文章对韧性概念的发展历程进行了梳理,并对比分析了不同韧性理论及其侧重点。在城市韧性多学科视角下,提出了城市洪涝灾害韧性的主要特征与核心内涵,并回顾了相关研究进展,同时指出了社区韧性评价的主要聚焦点。再次,论述了城市社区在面对洪涝灾害时的稳健性、适应性和可转换性特征。最后,从韧性治理的角度,构建了“制度-网络-能力”的分析框架,并详细阐释了城市社区洪涝灾害韧性分析的五个维度:制度韧性、组织韧性、社会韧性、基础设施韧性和技术韧性,以及这些维度之间的内容特征和逻辑联系。

关键词：灾害韧性脆弱性社区洪涝灾害治理气候变化灾害治理的复杂性工程韧性生态韧性演进韧性

Image Inpainting Based on Structural Tensor Edge Intensity Model

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International Journal of Automation and computing 2021年第2期18卷 256-265页

作者： Jing Wang Yan-Hong Zhou hai-feng Sima Zhan-Qiang Huo Ai-Zhong mi College of Computer Science and Technology Henan Polytechnic UniversityJiaozuo 454003China

In the exemplar-based image inpainting approach,there are usually two major problems:the unreasonable calculation of priority and only considering the color features in the patch lookup *** this paper,we propose an image inpainting approach based on the structural tensor edge intensity ***,we use the progressive scanning inpainting method to avoid the image filling order being affected by the priority ***,we use the edge intensity model to build the patches similarity function for correctly identifying the local image ***,the balance operator is used to restrict the excessive propagation of structural information to ensure the correct structural *** experimental results show that the our approach is comparable and even superior to some state-of-the-art inpainting algorithms.

关键词： Exemplar-based technique image inpainting structural tensor edge intensity model structure propagation balance operator

Operation Risk Analysis of Electric Vehicle With Ultra-fast Charging Integrated to Distribution Network Considering the Bearing Capacity of Power System

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Dianwang Jishu/Power System Technology 2025年第1期49卷 187-197页

作者： Xu, Yanchun Li, Sijia Zhang, Tao mi, Lu Hubei Provincial Key Laboratory for Operation and Control of Cascaded Hydropower Station China Three Gorges University Hubei Province Yichang 443002 China Department of Electrical and Computer Engineering Texas A & M University TX 77840 United States

At present, the access of distributed generation and electric vehicles with ultra-fast charging to the distribution network will increase the operational risk of the system. Aiming at the problem that the existing risk assessment indicators fail to consider the system capacity effectively, this paper proposed a comprehensive index of risk assessment of distribution networks considering the power system's capacity. The distributed generation output model and the electric vehicle load model with ultra-fast charging were first constructed. Then, the index based on the distribution entropy theory was used to measure the risk caused by the over-limit of state variables such as voltage and power and the uncertainty of their distribution. The index based on the Theil entropy theory was introduced to measure the risk caused by the equilibrium degree of the incremental distribution of state variables after the load impacted the system. The weight analysis method combining the order relationship method and the objective weighting method was used to evaluate the system risk comprehensively. Finally, the rationality of the comprehensive index was calculated and analyzed by testing the IEEE 33-node system. The results show that the comprehensive index proposed can effectively evaluate the potential risk when the system does not exceed the limit and consider that the ultra-fast charging of electric vehicles will change the time series distribution characteristics of comprehensive risk. The research in this paper can provide theoretical guidance for the safe operation of electric vehicles. with ultra-fast charging connected to the distribution network. © 2025 Power System Technology Press. All rights reserved.

关键词： Risk analysis