检索结果-南通市图书馆

Journal of Cotton Research 2020年第2期3卷 134-145页

作者： meeks calvin d SNIdER John L CULPEPPER Stanley HAWKINS Gary division of Plant Sciences University of MissouriPortagevilleMO 63873USA department of Crop and Soil Sciences University of GeorgiaTiftonGA 31793USA department of Crop and Soil Sciences University of GeorgiaWatkinsvilleGA 30677USA.

Background:This study addressed the potential of combining a high biomass rye winter cover crop with predawn leaf water potential(ΨPd)irrigation thresholds to increase agricultural water use efficiency(WUE)in *** this end,a study was conducted near Tifton,Georgia under a manually-controlled,variable-rate lateral irrigation system using a Scholander pressure chamber approach to measure leaf water potential and impose varying irrigation scheduling treatments during the growing season.ΨPdthresholds were-0.4 MPa(T1),-0.5 MPa(T2),and-0.7 MPa(T3).A winter rye cover crop or conventional tillage were utilized for T1-T3 as ***:Reductions in irrigation of up to 10%were noted in this study for the driest threshold(-0.7 MPa)with no reduction in lint yield relative to the-0.4 MPa and-0.5 MPa *** conditions during flowering(2014)limited plant growth and node production,hastened cutout,and decreased yield and WUE relative to ***:We conclude thatΨPdirrigation thresholds between-0.5 MPa and-0.7 MPa appear to be viable for use in aΨPdscheduling system with adequate yield and WUE for cotton production in the southeastern *** cover positively impacted water potential at certain points throughout the growing season but not yield or WUE indicating the potential for rye cover crops to improve water use efficiency should be tested under longer-term production scenarios.

关键词： Cotton Irrigation management Water use efficiency Cover crops Cotton sustainability

Effects of temperature and SO_3 on re-emission of mercury from activated carbon under flue gas conditions

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2019年第5期31卷 67-73页

作者： Michael Royko Benjamin Galloway Noah d.meeks Bihter Padak department of Chemical Engineering University of South Carolina Southern Company Services Inc.600 18th Street North

Mercury(Hg) is a toxic and bio-accumulating heavy metal that is predominantly released via the combustion of coal. due to its toxicity, the Environmental Protection Agency(EPA)has introduced Mercury and Air Toxics Standards(MATS) Rule regarding allowable Hg emissions. In order to reduce emissions, power plants have widely adopted activated carbon(AC) injection. AC injection has proven to be an effective method to reduce Hg emissions, but the re-emission of previously adsorbed Hg during unit operation, likely due to changing temperature or flue gas composition, could be problematic. This study specifically examined the effects of temperature and sulfur trioxide(SO3) concentration,by ramping temperature and SO3 concentration independently and simultaneously, on AC samples that are already exposed to flue gas and saturated in presence of Hg, sulfur dioxide(SO2) and nitric oxide(NO). Of these two suspected factors to cause re-emission,temperature had the greater impact and resulted in re-emission of both elemental and oxidized Hg with a greater fraction of oxidized Hg, which can be attributed to elemental Hg being more strongly bonded to the AC surface. Surprisingly, exposing the samples to increasing concentrations of SO3 had nearly no effect under the conditions examined in this study, possibly as a result of the samples being already saturated with sulfur prior to the SO3 ramp tests to simulate transient conditions in the plant.

关键词： Mercury re-emission Sulfur trioxide Activated carbon

Conducting health policy analysis in primary care research: turning clinical ideas into action

在线全文

学校读者我要写书评

暂无评论

Family Medicine and Community Health 2019年第2期7卷 53-59页

作者： Alina Engelman Ben Case Lisa meeks Michael d Fetters Health Sciences California State UniversityEast BayHaywardCaliforniaUSA department of Family Medicine University of MichiganAnn ArborMichiganUSA Family Medicine University of MichiganAnn ArborMichiganUSA

Healthcare guidelines play a prominent role in the daytoday practice of primary care providers,and health policy research leads to the formation of these *** policy research is the multidisciplinary approach to public policy explaining the interaction between health institutions,special interests and theoretical *** this article,we demonstrate how primary care providers can conduct high-impact health policy research using Eugene Bardach’s eightfold policy analysis framework in a primary care *** a medical case,a woman with a history of total hysterectomy had scheduled a visit for a Papanicolaou(Pap)smear screening test as part of a well-woman health check-up with a family medicine *** recommendations on Pap smear screening after total hysterectomy sparked an investigation using the US Preventive Services Task Force criteria for conducting a health policy *** illustrate broadly how clinical care dilemmas can be examined by using Bardach’s broadly applicable health policy framework in order to inform meaningful policy ***’s framework includes(1)defining the problem,(2)assembling evidence,(3)constructing alternatives,(4)selecting criteria,(5)projecting outcomes,(6)confronting trade-offs,(7)decision-making and(8)sharing the results of the *** policy analysis demonstrated insufficient evidence to recommend Pap test screening after hysterectomy and the findings contributed to national *** following Bardach’s steps,primary care researchers have a feasible and powerful tool for conducting meaningful health policy research and analysis that can influence clinical practice.

关键词： policy meaningful conducting

development of a miniaturized 3d organoid culture platform for ultra-high-throughput screening

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Molecular Cell Biology 2020年第8期12卷 630-643页

作者： Yuhong du Xingnan Li Qiankun Niu Xiulei Mo Min Qui Tingxuan Ma calvin J.Kuo Haian Fu department of Pharmacology and Chemical Biology and Emory Chemical Biology discovery Center Emory University School of MedicineAtlantaGAUSA department of Medicine Division of HematologyStanford University School of MedicineStanfordCAUSA

The recent advent of robust methods to grow human tissues as 3d organoids allows us to recapitulate the 3d architecture of tumors in an in vitro setting and offers a new orthogonal approach for drug ***,organoid culturing with extracellular matrix to support 3d architecture has been challenging for high-throughput screening(HTS)-based drug discovery due to technical *** genetically engineered human colon organoids as a model system,here we report our effort to miniaturize such 3d organoid culture with extracellular matrix support in high-density plates to enable *** first established organoid culturing in a 384-well plate format and validated its application in a cell viability HTS assay by screening a 2036-compound *** further miniaturized the 3d organoid culturing in a 1536-well ultra-HTS format and demonstrated its robust performance for large-scale primary compound *** miniaturized organoid culturing method may be adapted to other types of *** leveraging the power of 3d organoid culture in a high-density plate format,we provide a physiologically relevant screening platform to model tumors to accelerate organoid-based research and drug discovery.

关键词： human colon organoids KRAS^G12d 3d culture 384-well plate high-throughput screening(HTS) 1536-well plate ultra-HTS(uHTS)

A Comparison between the Mechanical Behaviour of Steel Wires and Ultra High Molecular Weight Poly Ethylene Cables for Sternum Closure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Materials Sciences and Applications 2011年第10期2卷 1367-1374页

作者： Roelof Marissen Mischa Nelis Mildred Janssens Michelle d. M. E. meeks Jos G. Maessen 不详

Sternum closure after open heart surgery is typically done with steel wires. Final approximation of sternal parts and connection is achieved by twisting the ends of the wire and bending the twisted assembly towards the sternum in order to minimize outward protrusion. Though this routine procedure is highly effective, some failures do occur, e.g. due to wire fracture. Fatigue fracture of the wires, e.g. due to coughing implies a failure risk. An alternative development is to make cables from gel spun Ultra High Molecular Weight Poly Ethylene (UHMWPE) fibres, such fibres are extremely strong, yet flexible, and if made as a very pure grade, they are highly bio compatible. The optimal connection technique will be different from that of steel. Connection will rather be with knotting than twisting. A new sternum closure and fixation technique has been developed for the sternum. Additionally, a testing technique was developed, for a connection of simulated sternum parts, using different materials according to their respective optimal connection method and subsequently testing the mechanical properties of the connection. Substantial differences were observed. The mechanical behaviour of twisted steel wire connection showed more scatter than the knotted UHMWPE cables and some initial slack was sometimes present in the twisted cables. The maximum attainable force in the steel wires was determined by “untwisting” due to the external load. The maximum force in the UHMWPE cables was determined by the knot strength, either slipping for small knots, or breaking of the cables at the knots for slip-improved knots. The maximum force on the knotted UHMWPE cables was substantially larger than the maximum force on the twisted steel wires. Fatigue tests were performed on both the steel solution and the UHMWPE cables solution. The performance was about similar, although the simulated sternum opening was smaller for the UHMWPE cables at higher load levels. Summarizing, the UHMWPE cables sh

关键词： Heart Surgery Load displacement Fracture deformation Twisting Knotting Slip Fatigue

Beclin 1-Vps34 complex architecture： Understanding the nuts and bolts of therapeutic targets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers in Biology 2015年第5期10卷 398-426页

作者： deanna H. Morris calvin K. Yip Yi Shi Brian T. Chait Qing Jun Wang department of Molecular and Cellular Biochemistry University of Kentucky Lexington KY 40536 USA department of Biochemistry and Molecular Biology The University of British Columbia Vancouver BC V6TIZ3 Canada Laboratory of Mass Spectrometry and Gaseous Ion Chemistry The Rockefeller University New York NY 10065 USA department of Toxicology and Cancer Biology University of Kentucky Lexington KY 40536 USA Markey Cancer Center University of Kentucky Lexington KY 40536 USA

Autophagy is an important lysosomal degradation pathway that aids in the maintenance of cellular homeostasis by breaking down and recycling intracellular contents. dysregulation of autophagy is linked to a growing number of human diseases. The Beclin 1-Vps34 protein-protein interaction network is critical for autophagy regulation and is therefore essential to cellular integrity. Manipulation of autophagy, in particular via modulation of the action of the Beclin I-Vps34 complexes, is considered a promising route to combat autophagy-related diseases. Here we summarize recent findings on the core components and structural architecture of the Beclin 1-Vps34 complexes, and how these findings provide valuable insights into the molecular mechanisms that underlie the multiple functions of these complexes and for devising therapeutic strategies.

关键词： Beclin 1 Vps34 Nrbf2 complex structure CX-MS EM inhibitor drag design

分析影响经济增长的决定因素。东盟+3的面板数据研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

分析影响经济增长的决定因素。东盟+3的面板数据研究

作者： calvin Chandra 上海财经大学

学位级别：硕士

本研究旨在考察2000-2020年间外国直接投资、通货膨胀、开放度、人类发展指数、全球治理指数和基尼指数对所有东盟+3(中国、日本和韩国)国家经济增长的影响。通过本研究,使用变量基尼将大大减少本研究中的观察次数,因此需要进行额外的... 详细信息

本研究旨在考察2000-2020年间外国直接投资、通货膨胀、开放度、人类发展指数、全球治理指数和基尼指数对所有东盟+3(中国、日本和韩国)国家经济增长的影响。通过本研究,使用变量基尼将大大减少本研究中的观察次数,因此需要进行额外的研究模型。使用包括基尼指数在内的面板最小二乘法得出的结果显示,外国直接投资、政治稳定、没有暴力/恐怖主义、控制腐败以及基尼指数都对东盟+3国家的经济增长产生了重大影响。而排除基尼指数和使用稳健最小二乘法的研究表明,外国直接投资、开放度和腐败控制都是东盟+3国家经济增长的重要因素。此外,还对仅东盟国家进行了另一项使用稳健最小二乘法的测试,贸易开放、发言权和问责制、政治稳定和没有暴力/恐怖主义、监管质量、法治和腐败控制都是影响仅东盟国家经济增长的重要因素。

关键词：经济增长东盟+3 面板数据

Numerical simulation of ultrashort-pulse reflectometry(USPR)on EAST

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Plasma Science and Technology 2023年第12期25卷 105-114页

作者：俞潇烽陈冉李小良朱逸伦 calvin W dOMIER 阮行磊黄泰豪郭晋林子钰徐国盛毛世峰 Neville C LUHMANN JR 叶民友 School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026People’s Republic of China Institute of Plasma Physics Chinese Academy of SciencesHefei 230031People’s Republic of China University of California at davis 1 Shields AvenueDavis CA 95616United States of America

The microwave reflectometer is a popular non-intrusive plasma density diagnostic instrument on tokamaks that provides centimeter and millisecond level *** ultrashort-pulse reflectometer(USPR)achieves plasma density measurement by emitting a chirped wave containing a broadband signal and measuring the time of flight from different frequency components.A USPR system is currently being built on EAST(Experimental Advanced Superconducting Tokamak)to meet the needs of diagnostic of the pedestal density evolution,such as high-frequency small edge-localized *** order to predict the density reconstruction of the EAST USPR system,this work presents a numerical simulation study of the beam propagation of the chirped wave of extraordinary waves(X-mode)in the plasma based on *** electron density profile has been successfully reconstructed by the reflection signal *** small gap between the right-hand cut-off layer and the electron cyclotron resonance layer,due to the low plasma density on the plasma edge,causes unexpected leakage from the transmitting microwave beam to the pedestal and the core *** kind of‘tunneling’effect will cause the reflected signal to have energy loss in the low-frequency *** study also discusses the influence of the poloidal magnetic field on the reflected *** spatial variation of the poloidal magnetic field will lead to the conversion between extraordinary(X)waves and ordinary(O)waves,which leads to energy loss in the reflected *** simulation results show that the‘tunneling’effect and the O-X mode conversion effect have little effect on the EAST USPR ***,the currently designed transmit power meets the working requirements.

关键词： reflectometer pedestal density profile beam mode conversion

乙型肝炎病毒母婴传播及其阻断研究的现状与存在问题

在线全文

学校读者我要写书评

暂无评论

中华肝脏病杂志 2010年第7期18卷 556-558页

作者：邹怀宾陈煜张华段钟平李杰庄辉梁晓峰 calvin Q.Pan 首都医科大学附属北京佑安医院人工肝中心北京100069 首都医科大学附属北京佑安医院肝病产科北京100069 北京大学医学部病原生物学系中国疾病预防控制中心免疫规划中心 Mount Sinai School of Medicine New York

HBV可经血液、母婴、性接触等多种途径传播,其中母婴传播是我国HBV传播的主要途径之一.乙型肝炎母婴阻断是指通过产前、产时,产后采取一系列措施对新生儿进行保护以减少感染HBV机会的方法.近年来,HBV的母婴阻断取得了较好效果,总体阻断... 详细信息

HBV可经血液、母婴、性接触等多种途径传播,其中母婴传播是我国HBV传播的主要途径之一.乙型肝炎母婴阻断是指通过产前、产时,产后采取一系列措施对新生儿进行保护以减少感染HBV机会的方法.近年来,HBV的母婴阻断取得了较好效果,总体阻断成功率约在90%以上,但仍有一定的失败率,在相关机制、方案优化等方面仍面临一些亟待解决的问题.

关键词：肝炎病毒,乙型母亲婴儿疫苗

在线全文

学校读者我要写书评

暂无评论

陌生的地方，熟悉的面孔

英语学习 2009年第6期 32-33页

作者： Elly Schull meeks

在故乡美国，我迷上了一本描绘都柏林风情的书，书中的每一张照片都令我心动；迁居到这里之后，寂寞的我有天突然发现，书里的人物赫然出现在我的眼前。

关键词：英语学习学习方法阅读翻译