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真空灭弧室配电开关断路器和接触器的高可靠性元件

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电气时代 2007年第12期 100-102,104页

作者： SLADE Paul G LI Wangpei mayo stephen SMITH R.Kirkland TAYLOR Erik D

自从20世纪50年代中期将真空灭弧室(VI)用作配电操作开关、断路器和接触器的电流分断元件以来,其作用逐步增强。在电路的开断和配电保护领域,该电气产品已经占统治地位。真空灭弧室甚至被引入到电力输送中的通断产品的领域上。真空灭弧... 详细信息

自从20世纪50年代中期将真空灭弧室(VI)用作配电操作开关、断路器和接触器的电流分断元件以来,其作用逐步增强。在电路的开断和配电保护领域,该电气产品已经占统治地位。真空灭弧室甚至被引入到电力输送中的通断产品的领域上。真空灭弧室受到追捧的原因有:结构紧凑、适用范围广、成本低、极好的电寿命和机械寿命,以及使用方便。其中,最重要的优点是公认的高可靠性。

关键词：真空灭弧室配电开关高可靠性接触器断路器元件电气产品操作开关

Neuropeptide cholecystokinin:a key neuromodulator for hippocampal functions

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Neural Regeneration Research 2025年第7期20卷 1991-1992页

作者： Fengwen Huang stephen Temitayo Bello Department of Neuroscience City University of Hong KongKowloon TongHong Kong Special Administrative RegionChina Center for Regenerative Medicine and Health Hong Kong Institute of Science&InnovationChinese Academy of SciencesHong Kong Special Administrative RegionChina

Spatial memory is crucial for survival within external surroundings and wild *** hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodulators shape its functions(Teixeira et al.,2018;Zhang et al.,2024).However,the landscape of neuromodulations in the hippocampal system remains poorly understood because most studies focus on classical monoamine neuromodulators,such as acetylcholine,serotonin,dopamine,and *** neuropeptides,comprising the most abundant neuromodulators in the central nervous system,play a pivotal role in neural information processing in the hippocampal ***(CCK),one of the most abundant neuropeptides,has been implicated in regulating various physiological and neurobiological statuses(Chen et al.,2019).CCK-A receptor(CCK-AR)and CCK-B receptors(CCK-BR)are two key receptors mediating the biological functions of CCK,both of which belong to class-A sevenfold transmembrane G protein-coupled receptors(Nishimura et al.,2015).CCK-AR preferentially reacts to sulfated CCK,whereas CCK-BR binds both CCK and gastrin with similar affinities(Ding et al.,2022).The expression patterns of CCK-AR and CCK-BR are distinct,implying that CCK has various functions in target *** instance,CCK-AR is widely expressed in the GI and brain subregions and is hence implicated in the control of digestive function and satiety ***,CCK-BR is abundantly and widely distributed in the central nervous system,which majorly regulates anxiety,learning,and memory(Ding et al.,2022).However,the roles of endogenous CCK and CCK receptors in regulating hippocampal function at electrophysiological and behavioral levels have received less attention.

关键词： abundant functions modulator

Human induced pluripotent stem cell-derived therapies for regeneration after central nervous system injury

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Neural Regeneration Research 2025年第11期20卷 3063-3075页

作者： stephen Vidman Yee Hang Ethan Ma Nolan Fullenkamp Giles W.Plant Department of Neuroscience Ohio State UniversityColumbusOHUSA

In recent years,the progression of stem cell therapies has shown great promise in advancing the nascent field of regenerative *** the non-regenerative nature of the mature central nervous system,the concept that“blank”cells could be reprogrammed and functionally integrated into host neural networks remained *** work has also demonstrated the ability of such cells to stimulate intrinsic growth programs in post-mitotic cells,such as *** embryonic stem cells demonstrated great potential in treating central nervous system pathologies,ethical and technical concerns *** barriers,along with the clear necessity for this type of treatment,ultimately prompted the advent of induced pluripotent stem *** advantage of pluripotent cells in central nervous system regeneration is multifaceted,permitting differentiation into neural stem cells,neural progenitor cells,glia,and various neuronal *** precise spatiotemporal application of extrinsic growth factors in vitro,in addition to microenvironmental signaling in vivo,influences the efficiency of this directed *** the pluri-or multipotency of these cells is appealing,it also poses the risk of unregulated differentiation and teratoma *** of the neuroectodermal lineage,such as neuronal subpopulations and glia,have been explored with varying degrees of *** the risk of cancer or teratoma formation is greatly reduced,each subpopulation varies in effectiveness and is influenced by a myriad of factors,such as the timing of the transplant,pathology type,and the ratio of accompanying progenitor ***,successful transplantation requires innovative approaches to develop delivery vectors that can mitigate cell death and support ***,host immune responses to allogeneic grafts must be thoroughly characterized and further developed to reduce the need for *** to a clinical setting wi

关键词： axon regeneration central nervous system regeneration induced pluripotent stem cells neurotrauma regenerative medicine spinal cord injury stem cell therapy

Convradiomics: Convolutional Radiomics Feature Extraction Toolkit

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Convradiomics: Convolutional Radiomics Feature Extraction To...

作者： OIHANE mayo IJURRA 上海交通大学

学位级别：硕士

Radiomics is a powerful tool in imaging-based clinical studies and it is gaining importance in oncology due to its ability to extract high-throughput image-based biomarkers in a non-invasive ***,common methods for extracting radiomics features are mainly designed in the CPU,being an extremely time-consuming process when complicated method verifications or large datasets are *** this study,a deep learning-based radiomics sequencer was developed that is capable to extract a total of 93 features,including all histogram and texture-based *** proposed network exploits the advantage of current CPU-based radiomics feature extraction methods because it has the potential to maintain the interpretability of radiomics features while reducing considerably the computation time of the feature extraction *** illustrate the effectiveness of the network,we perform the experiments on BRATS17 image dataset obtaining the mean squared error（MSE）of 0.00092 in training,0.0023 in validation and 0.00197 in test *** feature extraction process was completed in 22.21 seconds,being 72.05 times faster than conventional CPU-based *** this way,the potential advantages provided by the proposed network allow radiomics feature extraction process to be faster and more adaptive.

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Infuence of elemental composition in environmental impacts of steel

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Journal of Iron and Steel Research International 2020年第5期27卷 598-607页

作者： E.Batuecas C.mayo R.Diaz F.J.Perez Thermal and Fluid Engineering Department Carlos III University of Madrid28911 LeganesMadridSpain Chemical and Materials Engineering Department Complutense University of Madrid28040 MadridSpain Technical Sciences and Engineering UDIMA University28400 Collado VillalbaMadridSpain。

The environmental behavior of four steels was *** the operation phase of concentrating solar power plants,steels withstand high temperature because of its contact with molten ***,choosing the steel type for the molten salt tanks remains a great *** the cold tank,carbon steel is usually used although an approach with low chromium content steel is being studied for these ***,in high temperature applications,such as hot store tank,austenitic stainless steel is the most frequent ***,ferritic steel is being considered as a promising material in these *** many researchers studied the steel technical properties without considering their environmental damages,this work aimed to introduce the environmental aspects into the material choice by using the life cycle assessment *** one hand,the results showed the environmental adequacy of carbon steel against low chromium content *** the other hand,the results obtained in those steels suitable in high temperature application revealed signifcant environmental benefts from the ferritic steel instead of the austenitic steel.

关键词： Renewable energy Concentrating solar power Life cycle assessment Molten salt Ferritic steel Austenitic steel

Cytomegalovirus infection after liver transplantation

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World Journal of Transplantation 2020年第7期10卷 183-190页

作者： Blanca C Lizaola-mayo Eduardo A Rodriguez Division of Gastroenterology and Hepatology Mayo ClinicPhoenixAZ 85259United States Division of Gastroenterology Hepatology&NutritionUniversity of UtahSalt Lake CityUT 84132United States

Human cytomegalovirus(CMV)represents the most common opportunistic infection in liver transplant *** infections in post liver transplant patients cause significant morbidity and mortality,directly affecting posttransplant *** review will provide the framework for the surveillance,diagnosis,prophylaxis and treatment of CMV in the liver transplant population.

关键词： Cytomegalovirus Liver transplant Immunosuppression Serostatus

Autosub6000:A Deep Diving Long Range AUV

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Journal of Bionic Engineering 2009年第1期6卷 55-62页

作者： stephen McPhail Underwater Systems Laboratory National Marine Facilities DivisionNational Oceanography CentreSouthampton SO14 3ZHUK

With an ultimate range up to 1000 km,a maximum operating depth of 6000 m,and a generous payload capacity,Autosub6000 is well placed to become one of the world's most capable deep diving Autonomous Underwater Vehicles(AUVs). Recently,Autosub6000 successfully completed its first deep water engineering trials,and in September 2008,fitted with a multibeam sonar,will carry out its first science *** paper will describe how we are tackling the design issues that specifically affect a deep diving AUV which must be capable of operating with true autonomy,independently of the mother ship, namely:carrying adequate energy for long endurance and range,coping with varying buoyancy,and maintaining accurate navigation throughout missions lasting up to several *** from the recent engineering trails are presented,and future missions and development plans are discussed.

关键词： AUV robotics navigation lithium polymer battery deep ocean research

A COMPARISON OF SEALED AND VENTILATED ATTIC SPACES: A CASE STUDY OF RESIDENTIAL ATTIC DESIGN

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Journal of Green Building 2018年第3期13卷 89-100页

作者： Aneurin Grant Glenda mayo Andy Heitman Department of Instructional Workforce and Applied Technology University of West FloridaPensacolaFL The William States Lee College of Engineering Engineering Technology and Construction ManagementUniversity of North Carolina Charlotte Building Energy Sciences PensacolaFL

Two attics were constructed as part of a building renovation project at the University of West *** first attic is described as a traditional ventilated attic,with open-ings in the soffits and a small dormer vent on the *** second attic is described as a sealed attic(with no ventilation),and open-cell spray foam insulation installed on the underside of the roof *** study was undertaken to demonstrate hypoth-esized performance differences between attic *** and relative humidity sensors were installed to measure the condition of the air in the two attics spaces,and measurements were taken at 15 minute *** of relative humidity were later calculated as dew point and specific *** studies are often conducted by comparison of attics in separate buildings under different use *** project offers a unique opportunity to explore data collected from a single structure,and provides support for existing research on attic design in southern *** resultant data show significant differences in attic temperatures,with the sealed attic exhibiting a much more thermally stable *** were also significant differences in attic dew points and specific humidity,although these dif-ferences appear to be much less *** were analyzed using independent t-tests to establish significant differences between ***,the sealed attic performed better than the ventilated attic,although dew point and specific humidity remain concerns.

关键词： energy efficiency sealed attic ventilated attic roof design residential construction cool roof

The effect of bacterial challenge on ferritin regulation in the yellow fever mosquito, Aedes aegypti

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Insect Science 2013年第5期20卷 601-619页

作者： Dawn L. Geiser Guoli Zhou Jonathan J. mayo Joy J. Winzerling Department of Nutritional Sciences College of Agriculture and Life Sciences the University of Arizona Tucson Arizona 85721 USA

Secreted ferritin is the major iron storage and transport protein in insects. Here, we characterize the message and protein expression profiles of yellow fever mosquito （Aedes aegypti） ferritin heavy chain homologue （HCH） and light chain homologue （LCH） subunits in response to iron and bacterial challenge. In vivo experiments demonstrated tissue-specific regulation of HCH and LCH expression over time post-blood meal （PBM）. Transcriptional regulation of HCH and LCH was treatment specific, with differences in regulation for na？ve versus mosquitoes challenged with heat-killed bacteria （HKB）. Translational regulation by iron regulatory protein （IRP） binding activity for the iron-responsive element （IRE） was tissue-specific and time-dependent PBM. However, mosquitoes challenged with HKB showed little change in IRP/IRE binding activity compared to na？ve animals. The changes in ferritin regulation and expression in vivo were confirmed with in vitro studies. We challenged mosquitoes with HKB followed by a blood meal to determine the effects on ferritin expression, and demonstrate a synergistic, time-dependent regulation of expression for HCH and LCH.

关键词： Aedes aegypti bacteria ferritin iron IRP mosquito