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Epidemiological and Diagnostic Features of Non-Traumatic Gonalgia in Adults in Bouake (Ivory Coast): About 140 Patients

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Open Journal of Rheumatology and Autoimmune Diseases 2023年第4期13卷 78-87页

作者： Kouakou Ehaulier Soh Christian louis Sougué Charles Yao Konan Joe Clauvis Traore Aissata Koffi Joseph Kan Enock Goua jean Jacques Same Bebey Francine Goupille Phillipe Daboiko jean Claude Felix Rheumatology Department University Hospital Center Bouaké Bouaké C&#244te d’Ivoire Internal Medicine Department University Hospital Center Sour&#244 Sanou Bobo Dioulasso Burkina Faso Rheumatology Department Laquintinie Hospital Douala Cameroon Rheumatology Department University Hospital Center Tours France

Background: Non traumatic gonalgia is the second most common reason for rheumatology consultations and accounted for 15.6% of rheumatological disorders in Abidjan. Objective: The aim of this work was to study the epidemiological and diagnostic features of non-traumatic gonalgia (NTG) in a black adult population from sub-Saharan Africa. Patients and Methods: This was a five-year retrospective descriptive study (January 2014 to December 2018) of black sub-Saharan African adult patients with non traumatic gonalgia seen in the rheumatology department of the Bouake University Hospital in Côte d’Ivoire. Results: Of 2198 patients seen for rheumatological conditions, 140 had non traumatic gonalgia (6.4%). The mean age of patients was 56.13 ± 13.3 years (extremes 20 and 87 years), and the sex ratio was 0.43 (42 men and 98 women). Gonalgia without swelling was observed in 33.6% of cases. Symptoms were predominantly progressive (97.1%), chronic (82.1%) and bilateral (50%). The causes of TNM were gonarthrosis (85%), septic arthritis (7.1%), reactive arthritis (2.9%), gout (2.9%), rheumatoid arthritis (1.4%) and chondrocalcinosis (0.7%). Gonarthrosis (119/140) was bilateral in 65 patients, bi- or tri-compartmental in 83, radiographic stage (Kellgren and Lawrence) III in 80 and IV in 15. A germ was isolated in two cases of septic arthritis (methicillin-sensitive Staphylococcus aureus and Streptococcus pneumoniae). Conclusion: GNT is common in rheumatology practice in Bouake, and mainly affects women in their fifties. It is most often a chronic bilateral gonalgia, with gonarthrosis as the main etiology.

关键词： Non-Traumatic Gonalgia Gonarthrosis Bouake

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Shared Resource Quality Monitoring and Dynamic Trust Management in a Community Cloud

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Open Journal of Applied Sciences 2022年第11期12卷 1898-1914页

作者： Rodrigue N’goran Linda N. Vallee Grâce Y. E. Johnson jean-louis Tetchueng Yvon Kermarrec Olivier Asseu Lastic ESATIC Abidjan Ivory Coast University of Rennes 1 Rennes France Lab-STICC IMT-Atlantique Brest France

The collaboration tools offered by Cloud Computing have increased the need to share data and services within companies or between autonomous organizations. This has led to the deployment of community cloud infrastructures. However, several challenges will arise from this grouping of heterogeneous organizations. One of the main challenges is the management of trust between the actors of the community. Trust issues arise from the uncertainty about the quality of the resources and entities involved. The quality of a resource can be examined from a security or functional perspective. Therefore, ensuring security and monitoring the quality of resources is to ensure a high level of trust. Therefore, we propose in this paper a technique for dynamic trust management and quality monitoring of resources shared between organizations. Our approach consists, on the one hand, in evaluating the quality of resources based on quality of service measurement attributes and, on the other hand, in updating the trust values according to the information deduced from these measurements. The proposed framework is evaluated in terms of resource sharing success rate and execution time. Experimental results and comparison with TNA-SL and InterTrust models show that the framework can identify and track the behavior of malicious organizations with relatively low execution time.

关键词： SMI (Service Measure Index) Trust Management SLA QoS Community Cloud

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Sliding walls: a new paradigm for fluidic actuation and protocol implementation in microfluidics

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Microsystems & Nanoengineering 2020年第1期6卷 1093-1102页

作者： Bastien Venzac Yang Liu Ivan Ferrante Pablo Vargas Ayako Yamada Remi Courson Marine Verhulsel Laurent Malaquin jean-louis Viovy Stephanie Descroix Laboratoire Physico Chimie Curie Institut CuriePSL Research UniversityCNRS UMR16875005 ParisFrance Sorbonne Universites UPMC Univ Paris 0675005 ParisFrance Institut Pierre-Gilles de Gennes PSL Research University75005 ParisFrance Institut Curie PSL Research UniversityCNRS UMR 14475005 ParisFrance LAAS-CNRS Universitéde ToulouseCNRS31400 ToulouseFrance

Currently,fluidic control in microdevices is mainly achieved either by external pumps and valves,which are expensive and bulky,or by valves integrated in the *** types of internal valves or actuation methods have been proposed,but they generally impose difficult compromises between performance and fabrication *** propose here a new paradigm for actuation in microfluidic devices based on rigid or semi-rigid walls with transversal dimensions of hundreds of micrometres that are able to slide within a microfluidic chip and to intersect microchannels with hand-driven or translation stage-based *** this new concept for reconfigurable microfluidics,the implementation of a wide range of functionalities was facilitated and allowed for no or limited dead volume,low cost and low *** demonstrate here several fluidic operations,including on/off or switch valving,where channels are blocked or reconfigured depending on the sliding wall *** valves sustain pressures up to *** and reversible compartmentalisation of large microfluidic chambers were also *** last possibility was applied to a“4D”migration assay of dendritic cells in a collagen ***,sliding walls containing a hydrogel-based membrane were developed and used to concentrate,purify and transport biomolecules from one channel to another,such functionality involving complex fluidic transport patterns not possible in earlier microfluidic ***,this toolbox is compatible with“soft lithography”technology,allowing easy implementation within usual fabrication workflows for polydimethylsiloxane *** new technology opens the route to a variety of microfluidic applications,with a focus on simple,hand-driven devices for point-of-care or biological laboratories with low or limited equipment and resources.

关键词： walls hundreds operations

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Genetics of seed flavonoid content and antioxidant activity in cowpea(Vigna unguiculata L. Walp.)

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The Crop Journal 2016年第5期4卷 391-397页

作者： Maina Antoine Nassourou Yanou Nicolas Njintang Tchiagam jean-Baptiste Noubissié Richard Marcel Nguimbou Joseph martin Bell Department of Biological Sciences Faculty of Science University of Ngaoundéré Department of Food Science and Nutrition ENSAI University of Ngaoundéré Genetics and Plant Breeding Unit Department of Plant Biology Faculty of Science University of Yaoundé I

Information about the type of gene action governing the inheritance of cowpea seed flavonoid content and antioxidant activity is prerequisite for starting an effective breeding program for developing improved varieties. For this purpose, half-diallel crosses among seven diverse parents were made. The homozygous parents and 21 F1 hybrids were evaluated at Maroua in the Sudano-Sahelian zone of Cameroon using a randomized complete block design with three replicates. Flour samples produced from decorticated seeds were used for biochemical analysis. Analysis of variance showed significant differences(P < 0.001) among genotypes for the studied traits with ranges of 363.6–453.9 mg rutin equivalent per 100 g dry weight(DW) for total flavonoids, 13.38–30.73 mg ascorbic acid equivalent per 1 g DW for ferric iron reducing activity, 70.98–266.93 mg trolox equivalent per 100 g DW for 2,2-diphenyl-1-picrylhydrazyl(DPPH) free radical scavenging activity, and 90.93–370.62 mg trolox equivalent per 100 g DW for 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS) free radical scavenging activity. Both additive and non-additive gene effects were significant in the genetic control of these traits, but dominance variance was greater than additive variance. The traits were mainly controlled by overdominance model suggesting a selection in the delayed ***- and narrow-sense heritability estimates varied from 0.90 to 0.99 and from 0.12 to 0.45,respectively. The variances due to both general and specific combining ability were highly significant for all studied traits. Recessive alleles had positive effects on DPPH and ABTS scavenging activities, whereas dominant alleles had positive effects on flavonoid content and ferric iron reducing activity. These results could help cowpea breeders to improve the antioxidant potential of cowpea seeds by appropriate selection.

关键词： Cowpea Genetic improvement Diallel analysis Antioxidant properties

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The ecology of sexual dimorphism in size and shape of the freshwater blenny Salaria fluviatilis

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Current Zoology 2018年第2期64卷 183-191页

作者： martin LAPORTE Patrick BERREBI Julien CLAUDE Dolors VINYOLES Quim Pou-RoVIRA jean-Claude RAYMOND Pierre MAGNAN lnstitut des Sciences de I'Evolution de Montpellier (ISEM) UMR 5554 UM2-CNRS-IRD Universite de Montpellier II CC065 Place E. Bataillon Montpellier Cedex 534095 France Departement de Biologie Institut de Biologie Integrative et des Systemes (IBIS) Universite Laval Quebec Quebec City Canada G1V 0A6 Department of Evolutionary Biology Ecology and Environmental Sciences Faculty of Biology University of Barcelona Avda. Diagonal 643 Barcelona 08028 Spain Sorello estudis al medi aquatic Placa St. Pere 15 Baixos 17007 Girona Spain Office National de I'Eau et des Milieux Aquatiques (0NEMA) Unite Specialisee Milieux Lacustres Pisciculture de Rives 13 Quai de Rives Thonon-les-Bains 74200 France Centre de recherche sur les interactions bassins versants-ecosystemes aquatiques (RIVE) Universite du Quebec a Trois-Rivieres C. P. 500 Trois-Rivieres Quebec City Canada G9A 5H7

Sexual selection is considered the major cause of sexual dimorphism, but recent observations suggest that natural selection may play a more important role in the evolution of sex differentiation than previously recognized. Therefore, studying the trade-offs between natural selection and sexual selection is crucial to a better understanding of the ecology underlying the evolution of sexual dimorphism. The freshwater blenny , a fish inhabiting lakes and rivers around the Mediterranean Sea, displays strong sexual dimorphism in size, shape, and behavior (i.e., larger body and head size for males and higher swimming requirements for females during the reproductive period). We tested for differences in sexual dimorphism in size and shape between the populations from lake and river habitats with the goal of identifying the trade-offs between natural and sexual selection that underlie variations in sexual dimorphism in this species. Our results show i) differences in sexual size dimorphism (SSizeD) in accordance to Rensch's rule (i.e., larger individuals in rivers associated with higher SSizeD), and ii) a decrease in shape differentiation between males and females in lake populations. Together, this suggests that the different environmental conditions between lake and river habitats (e.g., resource limitations, predation pressure, water velocity) affect the relative importance of sexual selection in the display of sexual dimorphism within the species. This study highlights the importance of considering the environmental conditions to which populations are exposed to better understand the ecology underlying the evolution of sexual dimorphism.

关键词：生态学形状尺寸淡水鱼自然选择繁殖时期资源限制

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The Global Boundary Stratotype Section and Point （GSSP） for the base of the Pliensbachian Stage （Lower Jurassic）, Wine Haven, Yorkshire, UK

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Episodes 2006年第2期29卷 93-106页

作者： Christian Meister martin Aberhan Joachim Blau jean-louis Dommergues Susanne Feist-Burkhardt Ernie A. Hailwood Malcom Hart Stephen P. Hesselbos Mark W. Hounslow Mark Hylton Nicol Morton Kevin Page Greg D. Price Département de Géologie et de Paléontologie 1 route de Malagnou c.p. 6434 CH-1211 Genève 6 Switzerland Museum der Naturkunde Zentralinstitut der Humboldt-Universitat zu Berlin Institut für Palaiontolgie Invalidenstr. 43 D-10115 Berlin Germany Institut für Geowissenschaften Diezstrasse 15 D-35390 Giessen Germany Centre des Sciences de la Terre de I＇Université de Bourgogne UMR CNRS 5561： Paléontologie analytique et Géologie sédimentaire 6 Boulevard Gabriel F-21100 Dijon. France Department of Palaeontology The Natural History Museum Cromwell Road London SW7 5BD UK Core Magnetics The Green Sedbergh Cumbria LA10 5JS UK Department of Geological Sciences University of Plymouth Drake Circus Plymouth Devon PL4 8AA UK Department of Earth Sciences University of Oxford Parks Road Oxford OXI 3PR UK CEMP Geography Dept. Lancaster Environment Centre Lancaster University Bailrigg Lancaster UK. LA1 4YB Le Chardon Quarrier Brugière F-07200 Vogüé France

Following votes by the Pliensbachian Working Group, the Jurassic Subcommission and the International Commission on Stratigraphy, IUGS ratified the proposed Global Boundary Stratotype Section and Point (GSSP) for the base of the Pliensbachian Stage (Lower Jurassic) at the base of bed 73b in the Wine Haven section, Robin Hood's Bay, Yorkshire Coast, UK. This level contains the characteristic ammonite association Bifericeras donovani Dommergues and Meister and Apoderoceras sp. Complementary data include: a) Strontium-isotope stratigraphy, based on analysis of belemnites which yield a calcite 87Sr/86Sr ratio for the boundary level of 0.707425 and data supporting interpretation of continuous sedimentation; b) Belemnite oxygen-isotope data indicate a significant temperature drop (∼5 °C) across the boundary at this locality; c) A Transgressive Systems Tract (TST) initiated in the Aplanatum Subzone (uppermost Sinemurian) continues into the Lowermost Pliensbachian (Taylori Subzone); it forms part of a transgressive facies cycle sensu Graciansky et al. (1998); d) The Upper Sinemurian to lowermost Pliensbachian at Wine Haven section has a predominantly normal magnetic polarity, but two discrete reversed polarity magnetozones are present. The first spans much of the latest Sinemurian Aplanatum Subzone. It terminates <0.5m below the Sinemurian-Pliensbachian boundary and may prove a valuable chronostratigraphic marker. The second extends from the latest Oxynotum Subzone probably through to the lower part of the Raricostatum Subzone.

关键词：普连斯巴奇阶侏罗纪 GSSP 全球界线层型剖面点

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Urinary metabolic insights into host-gut microbial interactions in healthy and IBD children

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World Journal of Gastroenterology 2017年第20期23卷 3643-3654页

作者： Francois-Pierre martin Ming-Ming Su Guo-Xiang Xie Seu Ping Guiraud martin Kussmann jean-Philippe Godin Wei Jia Andreas Nydegger NestléInstitute of Health Sciences University of Hawaii Cancer Center Metabo-Profile Biotechnology(Shanghai)Co. Ltd. The Liggins Institute The University of Auckland NestléResearch Center Division of Pediatric Gastroenterology University of Lausanne

AIMTo identify metabolic signatures in urine samples from healthy and inflammatory bowel disease(IBD)*** applied liquid chromatography and gas chromatography coupled to targeted mass spectrometry(MS)-based metabolite profiling to identify and quantify bile acids and host-gut microbial metabolites in urine samples collected from 21 pediatric IBD patients monitored three times over one year(baseline,6 and 12 mo),and 27age-and gender-matched healthy *** metabolic profiles of IBD children differ significantly from healthy *** metabolic differences encompass central energy metabolism,amino acids,bile acids and gut microbial *** particular,levels of pyroglutamic acid,glutamic acid,glycine and cysteine,were significantly higher in IBD children in the course of the *** suggests that glutathione cannot be optimally synthesized and *** alterations of the enterohepatic circulation of bile acids in pediatric IBD patients is known,we show here that non-invasive urinary bile acid profiling can assess those altered hepatic and intestinal barrier *** present study shows how non-invasive sampling of urine followed by targeted MS-based metabonomic analysis can elucidate and monitor the metabolic status of children with different GI health/disease status.

关键词：小儿科新陈代谢显型生长煽动性的肠疾病 Crohns 疾病 Ulcerative 大肠炎

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Clinical Factors Influencing the Neurological Recovery of Patients Operated for a Cervical Myelopathy at the Teaching Hospital of Bouake

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Open Journal of Modern Neurosurgery 2023年第2期13卷 51-59页

作者： Derou louis Dongo Soress Yao Konan Serge Teti Landry Keke jean-Baptiste Fionko Yao Bernard Tokpa André Broalet Espérance Haidara Aderehime Neurosurgery Department Bouaké Teaching Hospital Bouaké Ivory Coast Neurosurgery Department Yamoussoukro Saint Joseph Moscatti’s Hospital Yamoussoukro Ivory Coast

Introduction: Cervical myelopathy is the most common myelopathy among people over 50 of age. Cervicosteoarthritis is the main etiology. The purpose of this work was to identify clinical factors that may influence neurological recovery in patients undergoing surgery for cervical myelopathy in our work setting. Materials and Methods: We performed a retrospective analytical study on patients operated on for cervical myelopathy at the teaching hospital of Bouake. The logistic regression model was used to identify the factors influencing post-operative neurological recovery. Results: 50 patients’ records have been enrolled in this study. The mean age of our patients was 53 years with extremes ranging from 25 to 78 years and 39 of our patients (62%) were male. The mean modified pre-operative JOA score was 11.62 versus 12.94 after the surgery. Age, sex, the number of levels operated on and the duration of the evolution of the signs showed no significant link with neurological recovery. Preoperative mild myelopathy (P = 0.0491) and post-operative functional rehabilitation (P = 0.0459) were identified as factors favouring neurological recovery after cervical myelopathy surgery. Conclusion: The good conducts of functional rehabilitation sessions as well as a mild myelopathy were the factors favouring neurological recovery.

关键词： Spinal Spondylosis Medullary Compression Myelopathy

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Age,smoking and overweight contribute to the development of intestinal metaplasia of the cardia

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World Journal of Gastroenterology 2012年第17期18卷 2076-2083页

作者： Christian Felley Hanifa Bouzourene Marianne Bründler G VanMelle Antoine Hadengue Pierre Michetti Gian Dorta Laurent Spahr Emiliano Giostra jean louis Frossard Service of Gastroenterology University Hospital1000 LausanneSwitzerland Institute of Pathology University Hospital1000 LausanneSwitzerland Institute of Social and Preventive Medicine University of Lausanne1000 LausanneSwitzerland Service of Gastroenterology Geneva University Hospital1211 GenevaSwitzerland

AIM:To assess the role of Helicobacter pylori(***),gastroesophageal reflux disease(GERD),age,smoking and body weight on the development of intestinal metaplasia of the gastric cardia(IMC).METHODS:Two hundred and seventeen patients scheduled for esophagogastroduodenoscopy were enrolled in this *** biopsies from the esophagus,gastroesophageal junction and stomach were evaluated for inflammation,the presence of *** and intestinal *** correlation of these factors with the presence of IMC was assessed using logistic ***:IMC was observed in 42% of the *** age,smoking habit and body mass index(BMI) were found as potential contributors to *** risk of developing IMC can be predicted in theory by combining these factors according to the following formula:Risk of IMC = a + s-2B where a = 2,…6 decade of age,s = 0 for non-smokers or ex-smokers,1 for 10 cigarettes/d and B = 0 for BMI 25 kg/m2(BMI > 27 kg/m2 in females).Among potential factors associated with IMC,*** had borderline signif icance(P = 0.07),while GERD showed no signif ***:Age,smoking and BMI are potential factors associated with IMC,while *** and GERD show no significant *** can be predicted in theory by logistic regression analysis.

关键词：吸烟者肠上皮年龄 Logistic回归分析 logistic回归幽门螺旋杆菌幽门螺杆菌超重

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Theoretical study of defect impact on two-dimensional MoS_2

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Journal of Semiconductors 2015年第12期36卷 18-23页

作者： Anna V.Krivosheeva Victor L.Shaposhnikov Victor E.Borisenko jean-louis Lazzari Chow Waileong Julia Gusakova Beng Kang Tay Belarusian State University of Informatics and Radioelectronics CNRS Aix-Marseille Université NOVITAS Nanoelectronics Centre of Excellence School of Electrical and Electronic Engineering Nanyang Technological University CINTRA CNRS NTUTHALES Nanyang Technological University

Our theoretical findings demonstrate for the first time a possibility of band-gap engineering of monolayer MoS2 crystals by oxygen and the presence of vacancies. Oxygen atoms are revealed to substitute sulfur ones, forming stable MoS2-xOx ternary compounds, or adsorb on top of the sulfur atoms. The substituting oxygen provides a decrease of the band gap from 1.86 to 1.64 eV and transforms the material from a direct-gap to an indirect-gap semiconductor. The surface adsorbed oxygen atoms decrease the band gap up to 0.98 eV depending on their location tending to the metallic character of the electron energy bands at a high concentration of the adsorbed atoms. Oxygen plasma processing is proposed as an effective technology for such band-gap modifications.

关键词： two-dimensional crystal molybdenum disulfide band gap vacancy oxygen

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