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sTGNN-LMR:A spatial–Temporal Graph Neural Network Approach Based on sEMG Lower Limb Motion Recognition

Journal of Bionic Engineering 2024年第1期21卷 256-269页

作者： Weifan mao Bin Ma Zhao Li Jianxing Zhang Yizhou Lu Zhuting Yu Feng Zhang shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China University of Chinese Academy of sciences Beijing 101408China University of science and Technology of China Hefei 230026China shanghai Zhongyan Jiuyi Technology Co. Ltd.Shanghai 201821China Academy of Military science Bejing 100091China

Lower limb motion recognition techniques commonly employ surface Electromyographic signal(sEMG)as input and apply a machine learning classifier or Back Propagation Neural Network(BPNN)for ***,this artificial feature engineering technique is not generalizable to similar tasks and is heavily reliant on the researcher’s subject *** contrast,neural networks such as Convolutional Neural Network(CNN)and Long short-term Memory Neural Network(LsTM)can automatically extract features,providing a more generalized and adaptable approach to lower limb motion *** this approach overcomes the limitations of human feature engineering,it may ignore the potential correlation among the sEMG *** paper proposes a spatial–temporal graph neural network model,sTGNN-LMR,designed to address the problem of recognizing lower limb motion from multi-channel ***-LMR transforms multi-channel sEMG into a graph structure and uses graph learning to model spatial–temporal *** 8-channel sEMG dataset is constructed for the experimental stage,and the results show that the sTGNN-LMR model achieves a recognition accuracy of 99.71%.Moreover,this paper simulates two unexpected scenarios,including sEMG sensors affected by sweat noise and sudden failure,and evaluates the testing results using hypothesis *** to the experimental results,the sTGNN-LMR model exhibits a significant advantage over the control models in noise scenarios and failure *** experimental results confirm the effectiveness of the sTGNN-LMR model for addressing the challenges associated with sEMG-based lower limb motion recognition in practical scenarios.

关键词： Lower limb motion recognition Exoskeleton sEMG.Graph neural network Noise sensor failure

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Evaluation of microRNA expression profiles in human sperm frozen using permeable cryoprotectant-free droplet vitrification and conventional methods

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Asian Journal of Andrology 2024年第4期26卷 366-376页

作者： Li-Xin Zhang Jing mao Yan-Dong Zhou Guang-Yao mao Run-Fa Guo Hong-shan Ge Xia Chen Department of Histology and Embryology Medical SchoolNantong UniversityNantong 226001China Department of Reproductive Medicine The Affiliated Taizhou People’s Hospital of Nanjing Medical UniversityTaizhou School of Clinical MedicineNanjing Medical UniversityTaizhou 225300China.

For sperm cryopreservation,the conventional method,which requires glycerol,has been used for a long *** addition,the permeable cryoprotectant-free vitrification method has been continuously *** the differences of cryopreservation effects between the two methods have being studied,differences in microRNA(miRNA)profiles between them remain *** this study,we investigated the differences in miRNA expression profiles among conventional freezing sperm,droplet vitrification freezing sperm and fresh human *** also analyzed the differences between these methods in terms of differentially expressed miRNAs(DEmiRs)related to early embryonic development and paternal *** results showed no significant differences between the cryopreservation methods in terms of sperm motility ratio,plasma membrane integrity,DNA integrity,mitochondrial membrane potential,acrosome integrity,and ultrastructural ***,sperm miRNA-sequencing showed differences between the two methods in terms of the numbers of DEmiRs(28 and 19 with vitrification using a nonpermeable cryoprotectant and the conventional method,respectively)in postthaw and fresh sperm *** related to early embryonic development and paternal epigenetics mainly included common DEmiRs between the *** results showed that the differences between conventional freezing and droplet vitrification were minimal in terms of miRNA expression related to embryonic development and *** in sperm miRNA expression due to freezing are not always detrimental to embryonic *** study compared differences in miRNA expression profiles before and after cryopreservation between cryopreservation by conventional and vitrification *** offers a new perspective to evaluate various methods of sperm cryopreservation.

关键词： cryopreservation cryoprotectant-free vitrification early embryonic development paternal epigenetic inheritance sperm miRNAs sucrose

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Diverse responses of fungal functional groups to desertification in forest soils of Pinus densata on the Chinese Tibetan plateau

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Journal of Forestry Research 2024年第5期35卷 120-130页

作者： Jiani Hua Jiangbao Zhang Baohan song Tianyi Wang Jingji Li Nan Yang Lingfeng mao Co-Innovation Center for sustainable Forestry in southern China Laboratory of Biodiversity and ConservationCollege of Ecology and EnvironmentNanjing Forestry University210037 NanjingPeople’s Republic of China Institute of Ecological Resources and Landscape Architecture Chengdu University of Technology610059 ChengduPeople’s Republic of China

Rapid increase in desertification is an environ-mental concern,especially for the health and sustainabil-ity of ecosystems in changing *** ecosystems respond to such changes may be partially understood by studying interactions and performance of critically impor-tant groups such as soil fungi functional *** study investigated variations in diversities of three soil fungi functional guilds(saprotrophic,symbiotic,pathogenic)and influencing abiotic factors in a Pinus densata forest on the southeast Tibetan Plateau where desertification is *** results indicate desertification significantly decreased the proportion of dominant fungal guild-symbiotic fungi(mean relative abundance decreasing from 97.0%to 68.3%),in contrast to saprotrophic fungi(increasing from 2.7%to 25.7%)and pathogenic(from 0.3%to 5.9%).soil pH had the most significant impact on fungal community structure and negatively correlated with symbiotic fungal richness,which was significantly lower in arid soils,and positively correlated with saprotrophic and pathogenic fungal alpha-diversity,which were *** community struc-tures and regulators of the three fungi communities were observed,with pH,total phosphorus and ammonium(NH_(4)^(+))as the main *** study links the biotic and abi-otic components during desertification and the interactions between them,and may be used as indicators of ecosystem health and for amendments to mitigate the effects of a chang-ing climate.

关键词： Desertification Fungal diversity saprotrophs Ectomycorrhizal fungi Climate change

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Decreasing productivity of pine forests on the southern edge of the Mongolian Plateau as indicated by tree rings

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Journal of Forestry Research 2024年第5期35卷 171-181页

作者： Zhuolan shen shijie Wang Feng Chen Heli Zhang Xiaoen Zhao Youping Chen mao Hu Yunnan Key Laboratory of International Rivers and Transboundary Eco‑security Institute of International Rivers and Eco‑SecurityYunnan UniversityKunming 650500People’s Republic of China southwest United Graduate school Kunming 650500People’s Republic of China Key Laboratory of Tree-Ring Physical and Chemical Research of China Meteorological Administration/Xinjiang Laboratory of Tree-Ring Ecology Institute of Desert MeteorologyChina Meteorological AdministrationÜrümqi 830002People’s Republic of China

Vegetation productivity on the southern edge of the Inner Mongolian Plateau,which plays a vital role in the ecological environment and in the arable and pasto-ral production in this region,can be characterized by the NDVI(normalized difference vegetation index).However,the observed NDVI data span only the last~40 *** growth of Pinus tabulaeformis *** strongly correlated with the NDVI,making it a valuable proxy for extend-ing the length of observed NDVI *** this study,we reconstructed an NDVI series for 1776–2021 for the Daqing Mountains,based on a tree-ring width *** reconstructed data accounted for 55%of the variance in the observed data,and its statistical characteristics and validation indicate that the reconstruction is *** correlation analysis demonstrated the consistency of climate signals in central Inner Mongolia in both the arable and pastoral *** results of superposed epoch analysis revealed a good temporal consistency between drought and flood events and the reconstructed NDVI sequence in this region.

关键词： Drought semi-arid area Peru current Yinshan Mountains

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Psychological intervention based on social cognitive theory: Treating pain, anxiety, and depression in perioperative patients

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World Journal of Psychiatry 2024年第8期14卷 1199-1207页

作者： Hai-Jian mao Lin-Fei Wang Chun Lin Department of surgical Anesthesiology The First People’s Hospital of Lin’an DistrictHangzhouHangzhou 311300Zhejiang ProvinceChina Department of Gastrointestinal surgery Hangzhou First People’s HospitalHangzhou 310006Zhejiang ProvinceChina Department of Comprehensive Intervention The First People’s Hospital of Lin’an DistrictHangzhouHangzhou 311300Zhejiang ProvinceChina

BACKGROUND surgery is an effective method for treating certain *** such as disease,preoperative fear and tension,surgical stress,postoperative pain,and related complications directly affect the smooth progression and outcome of *** may experience a series of psychological and physiological changes during the perioperative period,resulting in anxiety and depression,which may reduce the pain threshold and worsen their *** We enrolled 200 patients who underwent surgical care at The First People’s Hospital of Lin’an District,Hangzhou between January and December *** were categorized into a routine intervention group(n=103)and a psychological intervention group(n=97),based on the intervention strategies *** assessment tools,including the self-rating anxiety scale(sAs),the self-rating depression scale(sDs),and the Connor–Davidson Resilience scale,were used to measure patients’negative states and *** pre-and post-intervention scores for these metrics in the two groups were then *** In the psychological intervention group,the sAs and sDs scores(31.56±5.18 and 31.46±4.57,respectively)were significantly reduced compared to the routine intervention group(Psual analog scale pain scores at 12 and 24 hours after intervention(6.85±1.21,4.24±0.72)were notably higher than those in the routine intervention group(Psychological intervention group also demonstrated superior scores in perseverance(36.08±3.29),self-reliance(22.63±2.91),optimism(11.42±1.98),and resilience(70.13±5.37),compared to the routine intervention group(Psychological intervention group’s confrontation score(23.16±4.29)was higher(Ps group also reported lower scores in avoidance(9.28±1.94)and yielding(6.19±1.92)(Pstly,the short Form 36 Health survey scores were significantly higher in the psychological intervention group,indicating a better quality of life(PsION

关键词： Perioperative period social cognitive theory Psychological intervention Pain Anxiety and depression

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Imaging mass spectrometry:a molecular microscope for studying the role of lipids in Parkinson's disease

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Neural Regeneration Research 2024年第6期19卷 1179-1180页

作者： Vinata Vedam-Mai Jacob M.samuel Boone M.Prentice Department of Neurology University of FloridaGainesvilleFLUSA Department of Chemistry University of FloridaGainesvilleFLUSA

Parkinson's disease–A lipidopathy?The histopathological hallmark of Parkinson's disease(PD)and dementia with Lewy bodies are inclusions enriched inα-synuclein(α-syn),known as Lewy bodies,which are not only composed of proteins,but also a core of lipid *** has been thus far principally thought of as a“proteinopathy”caused by the misfolding of α-syn.

关键词： lipids species folding

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Efficacy and predictive factors of transarterial chemoembolization combined with lenvatinib plus programmed cell death protein-1 inhibition for unresectable hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1236-1247页

作者： Kun-Peng Ma Jin-Xin Fu Feng Duan mao-Qiang Wang Department of Interventional Radiology The Fifth Medical Center of Chinese People's Liberation Army General HospitalBeijing 100853China Chinese People's Liberation Army Medical school Beijing 100853China

BACKGROUND The efficacy and safety of transarterial chemoembolization(TACE)combined with lenvatinib plus programmed cell death protein-1(PD-1)for unresectable hepato-cellular carcinoma(HCC)have rarely been evaluated and it is unknown which factors are related to *** To evaluate the efficacy and independent predictive factors of TACE combined with lenvatinib plus PD-1 inhibitors for unresectable *** This study retrospectively enrolled patients with unresectable HCC who received TACE/lenvatinib/PD-1 treatment between March 2019 and April *** survival(Os)and progression-free survival(PFs)were *** objective response rate(ORR)and disease control rate(DCR)were evaluated in accordance with the modified Response Evaluation Criteria in solid ***,the prognostic factors affecting the clinical outcome were *** One hundred and two patients were enrolled with a median follow-up duration of 12.63 *** median Os was 26.43 months(95%CI:17.00-35.87),and the median PFs was 10.07 months(95%CI:8.50-11.65).The ORR and DCR were 61.76%and 81.37%,*** patients with Barcelona Clinic Liver Cancer Classification(BCLC)B stage,early neutrophil-to-lymphocyte ratio(NLR)response(decrease),or early alpha-fetoprotein(AFP)response(decrease>20%)had superior Os and PFs than their *** This study showed that TACE/lenvatinib/PD-1 treatment was well tolerated with encouraging efficacy in patients with unresectable *** patients with BCLC B-stage disease with early NLR response(decrease)and early AFP response(decrease>20%)may achieve better clinical outcomes with this triple therapy.

关键词： Transarterial chemoembolization Efficacy Lenvatinib Programmed cell death protein-1 inhibitors Unresectable hepatocellular carcinoma

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Pillar effect induced by ultrahigh phosphorous/nitrogen doping enables graphene/MXene film with excellent cycling stability for alkali metal ion storage

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Journal of Energy Chemistry 2024年第6期93卷 146-156,I0004页

作者： Meng Qin Yiwei Yao Junjie mao Chi Chen Kai Zhu Guiling Wang Dianxue Cao Jun Yan Key Laboratory of superlight Materials and surface Technology Ministry of EducationCollege of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001HeilongjiangChina Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials and Xiamen Institute of Rare Earth MaterialsHaixi InstituteChinese Academy of SciencesXiamen 361021FujianChina

Graphene's large theoretical surface area and high conductivity make it an attractive anode material for potassium-ion batteries(PIBs).However,its practical application is hindered by small interlayer distance and long ion transfer ***,this paper aims to address the issue by introducing MXene through a simple and scalable method for assembling graphene and realizing ultrahigh P doping *** findings reveal that MXene and P-C bonds have a "pillar effect" on the structure of graphene,and the P-C bond plays a primary *** addition,N/P co-doping introduces abundant defects,providing more active sites for K^(+) storage and facilitating K^(+) *** expected,the developed ultrahigh phosphorous/nitrogen co-doped flexible reduced graphene oxide/MXene(NPrGM) electrode exhibits remarkable reversible discharge capacity(554 mA hg^(-1) at 0.05 A g^(-1)),impressive rate capability(178 mA h g^(-1) at 2 A g^(-1)),and robust cyclic stability(0.0005% decay per cycle after 10,000 cycles at 2 A g^(-1)).Furthermore,the assembled activated carbon‖NPrGM potassium-ion hybrid capacitor(PIHC) can deliver an impressive energy density of 131 W h kg^(-1) and stable cycling performance with 98.1% capacitance retention after5000 cycles at 1 A g^(-1).such a new strategy will effectively promote the practical application of graphene materials in PIBs/PIHCs and open new avenues for the scalable development of flexible films based on two-dimensional materials for potential applications in energy storage,thermal interface,and electromagnetic shielding.

关键词： Graphene MXene Phosphorous doping Pillar effect Potassium-ion batteries

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Ten-Minute synthesis of a New Redox-Active Aqueous Binder for Flame-Retardant Li-s Batteries

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Energy & Environmental Materials 2024年第2期7卷 48-57页

作者： Tianpeng Zhang Borui Li Zihui song Wanyuan Jiang siyang Liu Runyue mao Xigao Jian Fangyuan Hu school of Materials science and Engineering State Key Laboratory of Fine ChemicalsFrontiers Science Center for Smart Materials Oriented Chemical Engineering Technology Innovation Center of High Performance Resin Materials(Liaoning Province)Key Laboratory of Energy Materials and Devices(Liaoning Province)Dalian University of TechnologyDalian 116024China state Key Laboratory of Fine Chemicals Frontiers Science Center for Smart Materials Oriented Chemical EngineeringSchool of Chemical Engineering Technology Innovation Center of High Performance Resin Materials(Liaoning Province)Key Laboratory of Energy Materials and Devices(Liaoning Province)Dalian University of TechnologyDalian 116024China

As a critical role in battery systems,polymer binders have been shown to efficiently suppress the lithium polysulfide shuttling and accommodate volume changes in recent ***,preparation processes and safety,as the key criterions for Li-s batteries'practical applications,still attract less ***,an aqueous multifunction binder(named PEI-TIC)is prepared via an easy and fast epoxy-amine ring-opening reaction(10 min),which can not only give the sulfur cathode a stable mechanical property,a strong chemical adsorption and catalytic conversion ability,but also a fire safety *** Li-s batteries based on the PEI-TIC binder display a high discharge capacity(1297.8 mAh g^(-1)),superior rate performance(823.0 mAh g^(-1)at 2 C),and an ultralow capacity decay rate of 0.035%over more than 800 *** under 7.1 mg cm^(-2)s-loaded,the PEI-TIC electrode can also achieve a high areal capacity of 7.2 mA h g^(-1)and excellent cycling stability,confirming its application ***,it is also noted that TG-FTIR test is performed for the first time to explore the flame-retardant mechanism of polymer *** work provides an economically and environmentally friendly binder for the practical application and inspires the exploration of the flame-retardant mechanism of all electrode components.

关键词： 3D cross-linked network environmentally friendly flame retardant Li-s batteries multifunction binder

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Clinical characteristics and treatment compounds of obesity-related kidney injury

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World Journal of Diabetes 2024年第6期15卷 1091-1110页

作者： Tuo-Hua mao Han-Qi Huang Chuan-Hai Zhang Department of Endocrinology Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina Department of Endocrinology Hubei No.3 People’s Hospital of Jianghan UniversityWuhan 430033Hubei ProvinceChina Department of Physiology UT Southwestern Medical CenterDallasTX 75390United States

Disorders in energy homeostasis can lead to various metabolic diseases,particularly *** obesity epidemic has led to an increased incidence of obesityrelated nephropathy(ORN),a distinct entity characterized by proteinuria,glomerulomegaly,progressive glomerulosclerosis,and renal function *** and its associated renal damage are common in clinical practice,and their incidence is increasing and attracting great *** is a great need to identify safe and effective therapeutic modalities,and therapeutics using chemical compounds and natural products are receiving increasing ***,the summary is lacking about the specific effects and mechanisms of action of compounds in the treatment of *** this review,we summarize the important clinical features and compound treatment strategies for obesity and obesityinduced kidney *** also summarize the pathologic and clinical features of ORN as well as its pathogenesis and potential therapeutics targeting renal inflammation,oxidative stress,insulin resistance,fibrosis,kidney lipid accumulation,and dysregulated *** addition,detailed information on natural and synthetic compounds used for the treatment of obesity-related kidney disease is *** synthesis of detailed information aims to contribute to a deeper understanding of the clinical treatment modalities for obesity-related kidney diseases,fostering the anticipation of novel insights in this domain.

关键词： Compounds Obesity Kidney injury Obesity-related nephropathy Clinical features and treatment

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