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Subtle traps prediction using sequence stratigraphy and 3D seismic technology: A case study from Qikou depression in Huanghua basin

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Journal of Central South University of Technology 2005年第Z1期12卷 141-145页

作者： mao ning-bo dai ta-gen peng sheng-lin Key Laboratory of Exploration Technologies for Oil and Gas Resources Ministry of Education Yangtze University Jingzhou 434023 China School of Geoscience and Enviromental Engineering Central South University Changsha 410083 China School of Geoscience and Enviromental Engineering Central South University Changsha 410083 China School of Geoscience and Enviromental Engineering Central South University Changsha 410083 China

Forecasting subtle traps by sequence stratigraphy and 3D seismic data is a sensitive topic in hydrocarbon exploration. Research on subtle traps by geophysical data is the most popular and difficult. Based on the sufficiently drilling data, log data, core data and 3D seismic data, sediment sequence of Qikou depression, Huanghua basin was partitioned by using sequence stratigraphy theory. Each sediment sequence system mode was built. Sediment faces of subtle traps were pointed out. Dominating factors forming subtle traps were analyzed. Sandstone seismic rock physics and its response were studied in Tertiary System. Sandstone geophysical response and elastic modulus vary laws with pressure, temperature, porosity, depth were built. Experimental result and practice shows that it is possible using seismic information forecasting subtle traps. Integrated using geology, log, drilling data, special seismic processing technique, interpretation technique, high precision horizon calibration technique, 3D seismic visualizing interpretation, seismic coherence analysis, attribute analysis, logging-constrained inversion, time frequency analysis, subtle trapsobject is identified and interpreted. Finally, advantage object of subtle trap in this area was determined. bottomland sand stratigraphic and lithologic reservoirs in Qinan slope zone have been founded by means of high resolution 3D seismic data field technique, high resolution 3D seismic data processing technique and seismic wave impendence inversion technique.

关键词： Huanghua basin sequence stratigraphy subtle trap seismic exploration 3D seismic ultrasonic wave

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Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n

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Nuclear Science and Techniques 2024年第1期35卷 178-187页

作者： sheng-Da tang Yong-Hao Chen Jing-Yu tang Rui-Rui Fan Qiang Li Gong Li Dong Liu Zheng-Yao Jin Xing-Zhu Cui Tian-Xiang Chen Yi-Wei Yang Rong Liu Han Yi Yang Li Zhen Yang Qi An Hao-Fan Bai Jiang-bo Bai Jie Bao Ping Cao Qi-Ping Chen Zhen Chen Zeng-Qi Cui An-Chuan Fan Chang-Qing Feng Fan-Zhen Feng Ke-Qing Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Wei-Hua Jia Hao-yu Jiang Wei Jiang Zhi-jie Jiang ling Kang bo Li Chao Li Jia-Wen Li Xiao Li Jie Liu Shu-Bin Liu Guang-Yuan Luan Chang-Jun ning Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Xin tan Li-Jiao Wang peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Yong-Ji Yu Guo-Hui Zhang lin-Hao Zhang Mo-Han Zhang Qi-Wei Zhang Xian-peng Zhang Yu-Liang Zhang Yue Zhang Zhi-Yong Zhang mao-Yuan Zhao Lu-Ping Zhou Zhi-Hao Zhou Ke-Jun Zhu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China Institute of High-Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China USTC Archaeometry Laboratory University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Nondestructive and noninvasive neutron assays are essential applications of neutron techniques.Neutron resonance transmission analysis(NRta)is a powerful nondestructive method for investigating the elemental composition of an object.The back-streaming neutron line(Back-n)is a newly built time-of-flight facility at the China Spallation Neutron Source(CSNS)that provides neutrons in the eV to 300 MeV range.A feasibility study of the NRta method for nuclide identification was conducted at the CSNS Back-n via two test experiments.The results demonstrate that it is feasible to identify different elements and isotopes in samples using the NRta method at Back-n.This study reveals its potential future applications.

关键词： CSNS White neutron beam NRta Nuclide identification Nondestructive method

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Induction chemotherapy with albumin-bound paclitaxel plus lobaplatin followed by concurrent radiochemotherapy for locally advanced esophageal cancer

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World Journal of Gastrointestinal Oncology 2021年第11期13卷 1781-1790页

作者： mao-Hui Yan Fang Liu Bao-lin Qu bo-ning Cai Wei Yu Xiang-Kun dai Department of Radiotherapy The First Medical Center of the Chinese People's Liberation Army(PLA)General HospitalBeijing 100853China

BACKGROUND Albumin-bound paclitaxel(ABP)has been used as second-and higher-line treatments for advanced esophageal cancer,and its efficacy and safety have been well demonstrated.Lobaplatin(LBP)is a third-generation platinum antitumor agent;compared with the first two generations of platinum agents,it has lower toxicity and has been approved for the treatment of breast cancer,small cell lung cancer,and chronic granulocytic leukemia.However,its role in the treatment of esophageal cancer warrants further investigations.AIM To investigate the efficacy and safety of induction chemotherapy with ABP plus LBP followed by concurrent radiochemotherapy(RCT)for locally advanced esophageal cancer.METHODS Patients with pathologically confirmed advanced esophageal squamous cell carcinoma(ESCC)at our hospital were enrolled in this study.All patients were treated with two cycles of induction chemotherapy with ABP plus LBP followed by concurrent RCT:ABP 250 mg/m^(2),ivgtt,30 min,d1,every 3 wk;and LBP,30 mg/m^(2),ivgtt,2 h,d1,every 3 wk.A total of four cycles were scheduled.The dose of the concurrent radiotherapy was 56-60 Gy/28-30 fractions,1.8-2.0 Gy/fraction,and 5 fractions/wk.RESULTS A total of 29 patients were included,and 26 of them completed the treatment protocol.After the induction chemotherapy,the objective response rate(ORR)was 61.54%,the disease control rate(DCR)was 88.46%,and the progressive disease(PD)rate was 11.54%;after the concurrent RCT,the ORR was 76.92%,the DCR was 88.46%,and the PD rate was 11.54%.The median progression-free survival was 11.1 mo and the median overall survival was 15.83 mo.Cox multivariate analysis revealed that two cycles of induction chemotherapy followed by concurrent RCT significantly reduced the risk of PD compared with two cycles of chemotherapy alone(P=0.0024).Non-hematologic toxicities were tolerable,and the only grade 3 non-hematologic toxicity was radiation-induced esophagitis(13.79%).The main hematologic toxicity was neutropenia,and no grade 4 adverse event occurred.CONCLUSION Induc

关键词： Esophageal squamous cell carcinoma Esophagus cancer Induction chemotherapy Concurrent radiochemotherapy Radiotherapy Chemotherapy Albuminbound paclitaxel Lobaplatin

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Comprehensive treatment for gas gangrene of the limbs in earthquakes

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中华医学杂志(英文版) 2013年第20期126卷 3833-3839页

作者： WANG Yue LU bo HAO peng YAN Meng-ning dai Ke-rong Department of Orthopaedics Sichuan Provincial People's HospitalSichuan Academy of Medical Sciences Department of Orthopaedics the Ninth People's HospitalShanghai Jiao Tong University School of Medicine

Background Mortality rates for patients with gas gangrene from trauma or surgery are as high as 25%,but they increase to 50%-80%for patients injured in natural hazards.Early diagnosis and treatment are essential for these patients.Methods We retrospectively analyzed the clinical characteristics and therapeutic results of 19 patients with gas gangrene of the limbs,who were injured in the May 2008 earthquake in the Wenchuan district of China’s Sichuan province and treated in our hospital,to seek how to best diagnose and treat earthquake-induced gas gangrene.Results Of 226 patients with limbs open injuries sustained during the earthquake,53 patients underwent smear analysis of wound exudates and gas gangrene was diagnosed in 19 patients.The average elapsed time from injury to arrival at the hospital was 72 hours,from injury to definitive diagnosis was 4.3 days,and from diagnosis to conversion of negative findings on wound smear analysis to positive findings was 12.7 days.Anaerobic cultures were also obtained before wound closure.The average elapsed time from completion of surgery to recovery of normal vital signs was 6.3 days.Of the19 patients,16 were treated with open amputation,two with closed amputation,and 1 with successful limb salvage;18patients were successfully treated and one died.Conclusions In earthquakes,rapid,accurate screening and isolation are essential to successful treatment of gas gangrene and helpful in preventing nosocomial diffusion.Early and thorough debridement,open amputation,and active supportive treatment can produce satisfactory therapeutic results.

关键词： gas gangrene limb earthquakes

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Neoadjuvant chemoradiotherapy plus surgery in the treatment of potentially resectable thoracic esophageal squamous cell carcinoma

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World Journal of Clinical Cases 2020年第24期8卷 6315-6321页

作者： mao-Hui Yan bo-ning Cai Bao-lin Qu Xiang-Kun dai Fang Liu Xiao-Bin Hou Department of Radiotherapy The First Medical Center of the Chinese PLA General HospitalBeijing 100853China Department of Thoracic Surgery The First Medical Center of the Chinese PLA General HospitalBeijing 100853China

BACKGROUNDIn recent years, neoadjuvant chemoradiotherapy (NCRT) combined with surgeryhas been gradually applied in patients with locally advanced thoracic esophagealcancer, but its effectiveness and safety remains unclear. In this clinical trial, weprospectively investigated the efficacy and safety of NCRT plus surgery in thetreatment of thoracic esophageal squamous cell carcinoma (TESCC).AIMTo investigate the efficacy and safety of NCRT combined with surgery in thetreatment of potentially resectable TESCC.METHODSThirty patients with advanced TESCC hospitalized in our hospital from July2016 to June 2019 were prospectively studied. All patients received NCRT, whichincluded intensity modulated conformal radiotherapy (40-44 Gy/20-22f, 2 Gy/f)and chemotherapy (paclitaxel 150-175 mg/m2d1, 22 + lobaplatin 25-30 mg/m2d2,23 for two cycles). Surgery was performed after radiotherapy and chemotherapy.The effectiveness and safety of these treatments were observed.RESULTSAmong these 30 patients, complete response was achieved in two cases (6.7%) andpartial response in 26 cases (86.7%), yielding an objective response rate of 100%.All patients underwent radical surgery successfully. The R0 resection rate was100%, and the pathologic complete response rate was 33.3%. The incidence ofgrade III- IV granulocytopenia was 10% during the NCRT, and anastomoticleakage occurred in one patient after surgery.CONCLUSIONFor patients with potentially resectable TESCC, NCRT can effectively reduce thetumor size, increase R0 resection rate, and achieve obvious pathologicaldegradation, with mild adverse reactions. Thus, it is worthy of wider clinicalapplication.

关键词： Esophageal cancer Neoadjuvant chemoradiotherapy Surgical treatment Radiotherapy Chemotherapy Toxicity

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Primary Selection of MicroRNA Acting on Classical Swine Fever Virus in Swine Umbilical Vein Endothelial Cells

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畜牧兽医学报 2011年第B12期42卷 30-33页

作者： HOU bo ZHANG Yan-ming ning peng-bo KANG Kai DENG Li dai Chen rANG Qing-hai （College of Veterinary Medicine Northwest A ＆ F University Yangling 712100 China）

The aim of the study was to identify the microRNAs that act on classical swine fever virus (CSFV) in swine umbilical vein endothelial cells (SUVECs). The 3'-and 5'-untranslated regions ( UTR) of CSFV were cloned and then inserted into psiCHECH TM-2 plasmids carrying Firefly and Renilla luciferases reporter genes; microRNAs that acted with CSFV were predicted by bio-informatics analysis; then the recombinant plasmids and inhibitors of the predicted microRNA were co-transfected into SUVECs. The activities of Firefly and Renilla luciferases were detected by luminometry. The PCR products of the CSFV 5'-UTR (373 bp) and 3'-UTR (252 bp) were detected by electrophoresis on 1% agarose gels. Four microRNAs (ssc-miR-let7c, ssc-miR-106a, ssc-miR-18, ssc-miR-139) were screened out and evaluated. The CSFV 3'-UTR is the important target site of microRNA in SUVECs. The four microRNAs mentioned above had different inhibitory effects on the CSFV 3'-UTR, of which the ssc-miR-18 played the most important role.

关键词：脐静脉内皮细胞猪瘟病毒血管内皮细胞 microRNA 荧光素酶报告基因小分子RNA 重组质粒电泳检测

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Primary Selection of MicroRNA Acting on Classical Swine Fever Virus in Swine Umbilical Vein Endothelial Cells

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畜牧兽医学报 2011年第S1期 30-33页

作者： HOU bo,ZHANG Yan-ming,ning peng-bo,KANG Kai,DENG Li,dai Chen,taNG Qing-hai (College of Veterinary Medicine,Northwest A & F University,Yangling 712100,China)

The aim of the study was to identify the microRNAs that act on classical swine fever virus (CSFV) in swine umbilical vein endothelial cells (SUVECs). The 3’-and 5’-untranslated regions ( UTR) of CSFV were cloned and then inserted into psiCHECH TM-2 plasmids carrying Firefly and Renilla luciferases reporter genes; microRNAs that acted with CSFV were predicted by bio-informatics analysis; then the recombinant plasmids and inhibitors of the predicted microRNA were co-transfected into SUVECs. The activities of Firefly and Renilla luciferases were detected by luminometry. The PCR products of the CSFV 5’-UTR (373 bp) and 3’-UTR (252 bp) were detected by electrophoresis on 1% agarose gels. Four microRNAs (ssc-miR-let7c, ssc-miR-106a, ssc-miR-18, ssc-miR-139) were screened out and evaluated. The CSFV 3’-UTR is the important target site of microRNA in SUVECs. The four microRNAs mentioned above had different inhibitory effects on the CSFV 3’-UTR, of which the ssc-miR-18 played the most important role.

关键词： classical swine fever virus microRNA SUVECs

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Expert Consensus on Diagnosis and Treatment of End-Stage Liver Disease Complicated with Infections

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Infectious Diseases & Immunity 2022年第3期2卷 168-178页

作者： Qin ning tao Chen Guiqiang Wang Dong Xu Yanyan Yu Qing mao taisheng Li Lanjuan Li Jun Li Xiaoju Lu Jiabin Li Zhiwei Li Wenhong Zhang Yonghong Xiao Qinghua Meng Yuqiang Mi Jia Shang Yunsong Yu Yingren Zhao Caiyan Zhao Hong Zhao Jianrong Huang Jie peng Hong tang Xiaoping tang Jinhua Hu Bijie Hu Wei Guo bo Zheng Baiyi Chen Yuexin Zhang Jia Wei Jifang sheng Zhi Chen Minggui Wang Qing Xie Yuming Wang Fu-sheng Wang Jinlin Hou Zhongping Duan Lai Wei Jidong Jia Chinese Society of Infectious Disease of Chinese Medical Association Department of Infectious Disease Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Infectious Disease Center for Liver DiseasePeking University First HospitalBeijing 100034China Department of Infectious Diseases Southwest HospitalArmy Medical UniversityChongqing 400038China Department of Infectious Diseases Peking Union Medical College HospitalPeking Union Medical College and Chinese Academy of Medical SciencesBeijing 100730China State Key Laboratory for Diagnosis and Treatment of Infectious Diseases Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310003China Department of Infectious Disease The First Affiliated Hospital with Nanjing Medical UniversityNanjing 210029China Center of Infectious Diseases West China Hospital of Sichuan UniversityChengdu 610041China Department of Infectious Diseases First Affiliated Hospital of Anhui Medical UniversityHefei 230031China Department of Infectious Diseases Shengjing HospitalAffiliated Hospital of China Medical UniversityShenyang 110801China Department of Infectious Diseases Institute of Infectious DiseasesHuashan HospitalFudan UniversityShanghai 200040China Department of Severe Liver Diseases Beijing Youan HospitalCapital Medical UniversityBeijing 100069China Nankai University Second People’s Hospital Tianjin 300071China Department of Infectious Disease People’s Hospital of Henan ProvinceZhengzhou 450003China Department of Infectious Diseases Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310020China Department of Infectious Diseases First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061China Department of Infectious Diseases Third Affiliated Hospital of Hebei Medical UniversityShijiazhuang 050051China State Key Laboratory of Organ Failure Research Guangdong Provincial Key Laboratory of Viral Hepatitis ResearchDepartment o

End-stage liver disease(ESLD)is a life-threatening clinical syndrome that markedly increases mortality in patients with infections.In patients with ESLD,infections can induce or aggravate the occurrence of liver decompensation.Consequently,infections are among the most common complications of disease progression.There is a lack of working procedure for early diagnosis and appropriate management for patients with ESLD complicated by infections as well as local and international guidelines or consensus.This consensus assembled up-to-date knowledge and experience across Chinese colleagues,providing data on principles as well as working procedures for the diagnosis and treatment of patients with ESLD complicated by infections.

关键词： Consensus Diagnosis End stage of liver disease Infection Therapy

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边坡稳定性的多米诺骨牌模型分析方法

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岩土工程学报 2021年第1期43卷 112-120页

作者：陈文胜蒋茂林戴嘉宁丁博尹平保长沙理工大学土木工程学院湖南长沙410114

边坡稳定性分析的条分法现仍是边坡分析和评估的主要方法。然而,现今条分法分析均是基于整体分析思想,获得整体或常安全系数,这是一理想的模式。真实的边坡失稳一般是渐进的过程,而这种渐进的失稳模式与多米诺骨牌的失稳倒塌有很多相似... 详细信息

边坡稳定性分析的条分法现仍是边坡分析和评估的主要方法。然而,现今条分法分析均是基于整体分析思想,获得整体或常安全系数,这是一理想的模式。真实的边坡失稳一般是渐进的过程,而这种渐进的失稳模式与多米诺骨牌的失稳倒塌有很多相似之处。基于这种边坡渐进失稳的考虑,提出了一种新的分析边坡稳定性的条分方法,即多米诺骨牌模型分析方法(简称骨牌模型)。骨牌模型定义了每个条块的局部安全系数和边坡的安全系数,也即边坡的安全系数由控制条块的局部安全系数决定。而控制条块是在形成某一滑动面时,所有组成滑体条块中具有最大局部安全系数的条块。而边坡的安全系数则为所有滑动面所对应的控制条块的安全系数中,最小的安全系数。这样定义安全系数是出于骨牌模型的渐进破坏机制而考虑的,突破了传统条分法的整体或常安全系数的局限。给出了骨牌模型的求解方法和求解步骤,并通过算例分析了骨牌模型的求解特点。

关键词：边坡条分法多米诺骨牌模型控制条块

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钠离子电池复合负极材料MoSe_(2)@N,P-C的合成与性能研究

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Journal of Central South University 2022年第9期29卷 2991-3002页

作者：彭涛罗玉红汤林波贺振江闫澄毛景代克华吴贤文郑俊超 School of Metallurgy and Environment Central South UniversityChangsha 410083China National Engineering Research Center of Low-carbon Nonferrous Metallurgy (Central South University)Changsha 410083China Engineering Research Center of Ministry of Education for Advanced Battery Materials Central South UniversityChangsha 410083China School of Mechanical Medical and Process EngineeringQueensland University of TechnologyBrisbaneQueensland 4001Australia School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China College of Chemistry Tianjin Normal UniversityTianjin 300387China School of Chemistry and Chemical Engineering Jishou UniversityJishou 416000China School of Materials Science and Engineering Central South UniversityChangsha 410083China

在钠离子电池体系中,基于转化反应机理的负极材料具有极高的比容量。然而,这类材料的结构稳定性差,可能出现结构坍塌,限制其应用。本文采用水热法,合成了MoSe_(2)@N,P-C复合材料,作为钠离子电池负极材料。以有机溶剂作为插层剂,扩大MoSe... 详细信息

在钠离子电池体系中,基于转化反应机理的负极材料具有极高的比容量。然而,这类材料的结构稳定性差,可能出现结构坍塌,限制其应用。本文采用水热法,合成了MoSe_(2)@N,P-C复合材料,作为钠离子电池负极材料。以有机溶剂作为插层剂,扩大MoSe_(2)纳米片的层间距,从而提升其导电能力,并在后续烧结过程中引入碳源,使MoSe_(2)表面形成独特的碳层,实现纳米材料的表面杂化。这种方法制备的MoSe_(2)@N,P-C复合材料表现出优异的倍率性能,在大电流密度下进行充放电仍能维持其结构稳定。在0.5 A/g恒定电流密度下循环100圈后,其放电容量达302.4 mA·h/g,容量保持率为84.96%。

关键词：钠离子电池 MoSe_(2) 负极材料原子掺杂电化学性能

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