检索结果-南通市图书馆

Particle residence time distribution and axial dispersion coefficient in a pressurized circulating fluidized bed by using multiphase particle-in-cell simulation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2024年第5期69卷 167-176页

作者： Jinnan Guo Daoyin Liu Jiliang Ma cai Liang Xiaoping Chen Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education Southeast UniversityNanjing 210096China

The particle residence time distribution(RTD)and axial dispersion coefficient are key parameters for the design and operation of a pressurized circulating fluidized bed(PCFB).In this study,the effects of pressure(0.1-0.6 MPa),fluidizing gas velocity(2-7 m·s^(-1)),and solid circulation rate(10-90 kg·m^(-2)·s^(-1))on particle RTD and axial dispersion coefficient in a PCFB are numerically investigated based on the multiphase particle-in-cell(MP-PIC)*** details of the gas-solid flow behaviors of PCFB are *** on the gas-solid flow pattern,the particles tend to move more orderly under elevated *** an increase in either fluidizing gas velocity or solid circulation rate,the mean residence time of particles decreases while the axial dispersion coefficient *** an increase in pressure,the core-annulus flow is strengthened,which leads to a wider shape of the particle RTD curve and a larger mean particle residence *** back-mixing of particles increases with increasing pressure,resulting in an increase in the axial dispersion coefficient.

关键词： Pressurized circulating fluidized bed MP-PIC method Residence time distribution Axial dispersion coefficient

A Piezoelectrically Driven Microrobot Using a Novel Monolithic Spatial Parallel Mechanism as Its Hip Joint

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2024年第2期21卷 803-820页

作者： Guangping Wu Ziyang Wang Jiaxin Zhao Feng Cui Xinghan cai National Key Laboratory of Advanced Micro and Nano Manufacture Technology Shanghai Jiao Tong UniversityShanghai200240China Department of Micro-Nano Electronics School of Electronic Information and Electrical EngineeringShanghai Jiao Tong UniversityShanghai200240China

Inspired by the fast,agile movements of insects,we present a 1.9 g,4.5 cm in length,piezoelectrically driven,quadrupedal *** microrobot uses a novel spatial parallel mechanism as its hip joint,which consists of two spatially orthogonal slider-crank *** mechanism maps two inputs of two independent actuators to the decoupled swing and lift outputs of a leg,and each leg can produce the closed trajectories in the sagittal plane necessary for robot ***,the kinematics of the transmission are analyzed,and the parameters of the flexure hinges are designed based on geometrical constraints and yield *** hip joints,legs and exoskeletons are integrated into a five-layer standard laminate for monolithic fabrication which is composed of two layers of carbon fiber,two layers of acrylic adhesive and a polyimide *** measured output force(15.97 mN)of each leg is enough to carry half of the robot’s weight,which is necessary for the robot to move *** has been proven that the robot can successfully perform forward and turning *** to the microrobot fabricated with discrete components,the monolithically fabricated microrobot is more capable of maintaining the original direction of locomotion when driven by a forward signal and has a greater speed,whose maximum speed is 25.05 cm/s.

关键词： Insect-like Crawling microrobot Piezoelectric drive Parallel mechanism Monolithic fabrication

Ubiquitin-specific protease 21 promotes tumorigenicity and stemness of colorectal cancer by deubiquitinating and stabilizing ZEB1

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第3期16卷 1006-1018页

作者： Jun-Jun Lin Ye-cai Lu Department of Gastrointestinal Surgery Chaohu Hospital of Anhui Medical UniversityChaohu 238000Anhui ProvinceChina

BACKGROUND Colorectal cancer(CRC)is one very usual tumor together with higher death ***-specific protease 21(USP21)has been confirmed to take part into the regulation of CRC progression through serving as a ***,the promotive function of USP21 has also discovered in the progression of ***1 has illustrated to be modulated by USP7,USP22 and USP51 in ***,the regulatory functions of USP21 on ZEB1 in CRC progression need more *** To investigate the relationship between USP21 and ZEB1 in CRC *** The mRNA and protein expressions were assessed through RT-qPCR,western blot and IHC *** interaction between USP21 and ZEB1 was evaluated through Co-IP and GST pull down *** cell proliferation was detected through colony formation *** cell migration and invasion abilities were determined through Transwell *** stemness was tested through sphere formation *** tumor growth was evaluated through in vivo mice *** In this work,USP21 and ZEB1 exhibited higher expression in CRC,and resulted into poor ***,the interaction between USP21 and ZEB1 was further *** was demonstrated that USP21 contributed to the stability of ZEB1 through modulating ubiquitination *** addition,USP21 streng-thened cell proliferation,migration and stemness through regulating *** last,through in vivo assays,it was illustrated that USP21/ZEB1 axis aggravated tumor *** For the first time,these above findings manifested that USP21 promoted tumorigenicity and stemness of CRC by deubiquitinating and stabilizing *** discovery suggested that USP21/ZEB1 axis may provide novel sights for the treatment of CRC.

关键词： Ubiquitin-specific protease 21 ZEB1 Stemness Colorectal cancer

Monitoring of Cell Membrane Microenvironment Based on DNA Nanodevices

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2024年第2期40卷 255-267页

作者： NAN Hexin cai Ming KUANG Shi NIE Zhou State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan Provincial Key Laboratory of Biomacromolecular Chemical BiologyHunan UniversityChangsha410082P.R.China

The cell membrane is a critical barrier for cellular homeostasis,integral to signaling and intercellular communication,and vital for understanding cellular functions and disease *** its microenvironment is crucial for uncovering the molecular basis of physiological and pathological processes associated with the cell membrane,driving the development of bioanalytical toolkits capable of dynamically monitoring the cell surface *** the continuous advancement of functional nucleic acids and dynamic DNA nanotechnology,DNA nanodevices with controllable nanosized geometry,specific molecular recognition,and selective membrane-localization properties offer a versatile platform for probing the cell membrane *** this review,we summarize the current biosensing and membrane-anchoring mechanisms of DNA nanodevices and highlight their use in studying key cell membrane events,including membrane lipid dynamics,transmembrane transport,receptor dimerization,and signal ***,we discuss the challenges and potential future applications of DNA nanodevices in advancing cell membrane biology research and biomedical applications.

关键词： DNA nanodevice Cell membrane Cellular micro-environment Monitoring

A LINEARLY-IMPLICIT STRUCTURE-PRESERVING EXPONENTIAL TIME DIFFERENCING SCHEME FOR HAMILTONIAN PDEs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Computational Mathematics 2024年第4期42卷 1063-1079页

作者： Yayun Fu Dongdong Hu Wenjun cai Yushun Wang Henan Joint International Research Laboratory of High Performance Computation for Comples Systems School of ScienceXuchang UniversityXuchang 461000China School of Mathematics and Statistics Jiangci Normal UniversityJiangciNanchang 330022China Jiangsu Key Laboratory for NSLSCS Jiangsu Collaborative Innovation Center of Biomedial Functional MaterialsSchool of Mathematical SciencesNanjing Normal UniversityNanjing 210023China

In the paper,we propose a novel linearly implicit structure-preserving algorithm,which is derived by combing the invariant energy quadratization approach with the exponential time differencing method,to construct efficient and accurate time discretization scheme for a large class of Hamiltonian partial differential equations(PDEs).The proposed scheme is a linear system,and can be solved more efficient than the original energy-preserving ex-ponential integrator scheme which usually needs nonlinear *** experiments are performed to verify the conservation,efficiency and good performance at relatively large time step in long time computations.

关键词： Structure-preserving algorithm Hamiltonian PDE Energy quadratization method Exponential time differencing

Heavier Group 14 Congeners of Metalla-isobenzenes:Access to Metalla-isosilabenzene and Metalla-isogermabenzene by One-Pot Reactions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2024年第10期42卷 1121-1127页

作者： Jinyu Zhao Yapeng cai Xin Yang Hong Zhang Department of Chemistry Xiamen UniversityXiamenFujian 361005China

Metalla-isosilabenzenes and metalla-isogermabenzenes have been successfully synthesized by the formal[5+1]-cycloaddition of diethynylsilane or diethynylgermane with simple metal *** is the first example of a heavier Group 14 metalla-isobenzene isomer bearing a cumulative double bond motif within a *** novel complexes were fully characterized by NMR spectroscopy and single-crystal X-ray diffraction *** stabilization of the cyclic metal-vinylidene complexes has been analyzed using density functional theory(DFT)*** the metalla-isosilabenzenes bearing Si—H bond were treated with the trityl salt as a hydride scavenger,the formation of silylium cation was observed *** of metalla-isosilabenzenes and metalla-isogermabenzenes can readily undergo migratory insertion reactions to furnish siloles or germoles.

关键词： Metalla-isosilabenzene Metalla-isogermabenzene Density functional calculations Cycloaddition Metallacycles

Study on the evolution of solid–liquid–gas in multi-scale pore methane in tectonic coal

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2024年第7期71卷 122-131页

作者： Junjie cai Xijian Li Hao Sui Honggao Xie College of Resources and Environmental Engineering Guizhou UniversityGuiyang 550025China Mining College Guizhou UniversityGuiyang 550025China

The rich accumulation of methane(CH_(4))in tectonic coal layers poses a significant obstacle to the safe and efficient extraction of coal seams and coalbed *** coal samples from three geologically complex regions were selected,and the main results obtained by using a variety of research tools,such as physical tests,theoretical analyses,and numerical simulations,are as follows:22.4–62.5 nm is the joint segment of pore volume,and 26.7–100.7 nm is the joint segment of pore specific surface *** the dynamic gas production process of tectonic coal pore structure,the adsorption method of methane molecules is“solid–liquid adsorption is the mainstay,and solid–gas adsorption coexists”.Methane stored in micropores with a pore size smaller than the jointed range is defined as solid-state *** within the jointed range,which transition from micropore filling to surface adsorption,are defined as gaseous *** outside the jointed range,where solid–liquid adsorption occurs,are defined as liquid *** evolution of pore structure affects the methane adsorption mode,which provides basic theoretical guidance for the development of coal seam resources.

关键词： Tectonic coal Multiscale pore structure Methane adsorption Micropore filling Monolayer Molecular simulation

Analysis on characteristics of extreme precipitation indices and atmospheric circulation in Northern Shanxi

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Cold and Arid Regions 2024年第2期16卷 84-97页

作者： Xia cai Yan Song Lin cai Xin Su GuiHua Liang YanMing Xu Shuozhou Meteorological Bureau of Shanxi Province ShuozhouShanxi 036002China China Meteorological Administration Training Center Beijing 100081China Heze University of Shandong Province HezeShandong 274000China Huafeng Meteorological Media Group Beijing 100081China Shuocheng Meteorological Bureau ShuozhouShanxi 036002China

This article utilizes daily precipitation data from 28 national meteorological stations in northern Shanxi Province spanning from 1972 to 2020,and the US NCEP/NCAR monthly average reanalysis and ERA5 monthly average reanalysis *** study employs techniques such as empirical orthogonal function(EOF)decomposition,MannKendall mutation and other methods to investigate the spatiotemporal distribution of extreme precipitation index in northern Shanxi and their correlation with atmospheric *** research results show that:the absolute index,relative index,intensity index and sustained dry period index(CDD)in the continuous index appear from southwest to *** spatial distribution characteristics of the central region decrease,while the continuous wet period(CWD)decreases from the central to the east and *** three indices Rx1day,Rx5day,and CWD mutated in 1978,1975,and 1983 respectively,and other extreme precipitation indices all appeared in a sudden change from a low-value period to a high-value period occurred around *** the high-value years of the summer extreme precipitation index,there is a significant negative anomaly in the height field in the mid-high latitude regions of *** Shanxi is controlled by a broad low-pressure trough in the Lake Baikal *** vapor transported via the east,west,and south routes converges in the northern Shanxi region and encounters cold air from the *** is a strong upward motion anomaly at 500 hPa in the troposphere,and the dynamic conditions of upper-level divergence and lower-level convergence lead to more summer extreme precipitation in the northern Shanxi ***,in the low-value years of the summer extreme precipitation index,northern Shanxi is affected by a strong high-pressure ridge north of Lake *** is a downward motion anomaly at 500 hPa,and the northern Shanxi region lacks water *** cold and warm air cannot converge,and both the water vapor conditions

关键词： Northern Shanxi Extreme precipitation indices Spatio-temporal distribution and evolution Mutations Atmospheric circulation anomaly

Machine learning-driven optimization of plasma-catalytic dry reforming of methane

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第9期96卷 153-163页

作者： Yuxiang cai Danhua Mei Yanzhen Chen Annemie Bogaerts Xin Tu Department of Electrical Engineering and Electronics University of LiverpoolLiverpool L693GJUK Research Group PLASMANT Department of ChemistryUniversity of AntwerpUniversiteitsplein 1BE-2610 Wilrijk-AntwerpBelgium College of Electrical Engineering and Control Science Nanjing Tech UniversityNanjing 211816JiangsuChina

This study investigates the dry reformation of methane(DRM)over Ni/Al_(2)O_(3)catalysts in a dielectric barrier discharge(DBD)non-thermal plasma reactor.A novel hybrid machine learning(ML)model is developed to optimize the plasma-catalytic DRM reaction with limited experimental *** address the non-linear and complex nature of the plasma-catalytic DRM process,the hybrid ML model integrates three well-established algorithms:regression trees,support vector regression,and artificial neural networks.A genetic algorithm(GA)is then used to optimize the hyperparameters of each algorithm within the hybrid ML *** ML model achieved excellent agreement with the experimental data,demonstrating its efficacy in accurately predicting and optimizing the DRM *** model was subsequently used to investigate the impact of various operating parameters on the plasma-catalytic DRM *** found that the optimal discharge power(20 W),CO_(2)/CH_(4)molar ratio(1.5),and Ni loading(7.8 wt%)resulted in the maximum energy yield at a total flow rate of∼51 mL/***,we investigated the relative significance of each operating parameter on the performance of the plasma-catalytic DRM *** results show that the total flow rate had the greatest influence on the conversion,with a significance exceeding 35%for each output,while the Ni loading had the least impact on the overall reaction *** hybrid model demonstrates a remarkable ability to extract valuable insights from limited datasets,enabling the development and optimization of more efficient and selective plasma-catalytic chemical processes.

关键词： Plasma catalysis Machine learning Process optimization Dry reforming of methane Syngas production