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Simulation of Cobalt-Rich Crust’s Crushing Process Based on ANSYS

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Journal of China University of Mining and Technology 2006年第1期16卷 28-32页

作者： XIA Yi-min ma zhi-guo BU Ying-yong ZHAO Hai-ming College of Mechanical and electronic Engineering Central South University Changsha Hunan 410083 China

It is a great concern in international oceanology to mine cobalt-rich crust. At present, spiral mining head is regarded as the best crushing scheme. Based on the dynamic model of spiral mining head, the of cobalt crust’s crushing process was simulated with the ANSYS software. The material model of Johnson and Cook Plasticity, maximal princi- pal stress failure criterion, and eroding contact arithmetic were selected. At the same time, the influence of cutting depth, feed speed, rotational speed of mining head on torque and force subjected by mining head was taken into account. At last a computer simulation model of crushing process of cobalt crust was established. By analyzing simulation results, the relationships among these controllable process parameters, torque and force can be obtained, which will provide a technical reference for practical mining system.

关键词： cobalt-rich crust mining head simulation finite element ANSYS

Isolation and Characterization of GmSTY1,a Novel Gene Encoding a Dual-Specificity Protein Kinase in Soybean（ Glycme max L.）

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Journal of Integrative Plant Biology 2006年第7期48卷 857-866页

作者： Zhao-Shi Xu You-zhi ma Xian-guo Cheng Li-Xia Cao Lian-Cheng Li Ming Chen Key Laboratory of Crop Genetics and Breeding Ministry of Agriculture Institute of Crop Science the Chinese Academy of Agricultural Sciences Beijing 100081 China

Phosphorylation of protein klnases has profound effects on their activity and interaction with other proteins. Tyroslne phosphorylation was reported to be involved in various physiological processes in plants; however, no typical receptor tyrosine kinase has been isolated from plants thus far. Dual-specificity kinases are potentially responsible for the phosphorylation of both tyrosine and serine/threonine of target proteins. A cDNA clone encoding a putative dual-specificity protein kinase was isolated by screening the cDNA GAL4 activation domain （AD） fusion library of soybean （Glycine max L.）, and its entire length was obtained using 5＇-rapid ampUflcatlon of cDNA ends. The predicted polypeptide of 330 amino acid residues, designated as GmSTY1, contains all 11 conserved subdomains, which share common characteristics with both the serine/ threonine and tyroslne protein klnases reported thus far. In addition, three potential N-linked glycosylation sites （NXS/T）, as well as phosphorylation motifs （SXXXS/T）, were observed, suggesting that GmSTY1 may be post-translationally modified. Furthermore, a potential N-myristoylation motif （MGARCSK） was found, suggesting that the GmSTY1 protein could associate with membranes in vivo. Southern blotting analysis revealed a single-copy of GmSTY1 in the genome. Northern blotting analysis showed that this gene was upregulated by drought and salt treatment in a time-dependent manner; however, exogenous abscisic acid （ABA） could not significantly affect the mRNA accumulation of GmSTY1. Interestingly, the transcript of this gene was remarkably downregulated by cold treatment during the early stages of the response, but upregulated later. These results Indicate that the protein kinase was possibly regulated by abiotic stresses in an ABA-independent pathway.

关键词： abiotic stress dual-specificity Glycine max , serine/threonine/tyrosine protein kinase.

Identification of poliumoside metabolites in rat plasma, urine, bile, and intestinal bacteria with UPLC/Q-TOF-MS

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Chinese Journal of Natural Medicines 2018年第11期16卷 871-880页

作者： QIAN Hao YU Fang-Jun LU Dan-Yi WU Bao-Jian ZHANG Xing-Wang WANG Huan ma zhi-guo College of Pharmacy Jinan University

Poliumoside is representative of phenylethanoid glycosides, which are widely found in many plants. Poliumoside is also regarded as the main active component of Callicarpa kwangtungensis Chun(CK), though its oral bioavailability in rat is extremely low(0.69%) and its in vivo and in vitro metabolism has not yet been systematically investigated. In the present study, an ultra performance liquid chromatography/quadrupole time-of-flight mass spectrometry(UPLC/Q-TOF-MS) method was employed to identify the metabolites and investigate the metabolic pathways of poliumoside in rat after oral administration 1.5 g·kg–1 of poliumoside. As a result, a total of 34 metabolites(30 from urine, 17 from plasma, and 4 from bile) and 9 possible metabolic pathways(rearrangment, reduction, hydration, hydrolyzation, dehydration, methylation, hydroxylation, acetylation, and sulfation) were proposed in vivo. The main metabolite, acteoside, was quantified after incubated with rat intestinal bacteria in vitro. In conclusion, the present study systematically explored the metabolites of poliumoside in vivo and in vitro, proposing metabolic pathways that may be significant for further metabolic studies of poliumoside.

关键词： Poliumoside Rat Metabolites Intestinal bacteria UPLC/Q-TOF-MS

媒体收视率调查公司样本户数据的商业秘密保护——对国内首例干扰样本户信息案件的分析

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西安交通大学学报（社会科学版） 2011年第2期31卷 61-66页

作者：马治国西安交通大学法学院陕西西安710049

在对国内首起收视率数据侵权案件分析的基础上,对此类特殊经营信息的认定与保护提出法律建议;认为商业秘密的本质是信息,包含技术信息与经营信息;相对而言,技术信息比较"硬",更容易被理解和保护,而经营信息比较"软",往往难以界定,保护... 详细信息

在对国内首起收视率数据侵权案件分析的基础上,对此类特殊经营信息的认定与保护提出法律建议;认为商业秘密的本质是信息,包含技术信息与经营信息;相对而言,技术信息比较"硬",更容易被理解和保护,而经营信息比较"软",往往难以界定,保护起来也更加困难;针对于从事媒体的收视率调查公司而言,其提供的调查数据就是其主营业务的产品,以数据所包含的信息为媒体提供服务,获得相应的报酬;该信息是生产要素、主导产品和企业财产,同时也属于商业秘密,应当受到保护。

关键词：知识产权收视率调查样本户数据商业秘密

学校教育中培养学生实践能力的基本模式及启示——建国后17年(1949年-1966年)的教育成就研究

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教育科学 2005年第4期21卷 21-24页

作者：马治国辽宁师范大学田家炳教育书院暨教育学院辽宁大连116029

建国之初的17年里,学校教育在培养学生实践能力方面形成了一些基本模式,如校内模式、校外模式和半工半读模式等。这些基本模式是对比较充足的、翔实的教育实践历史资料进行了全面、深入的研究而概括出来的,对当代素质教育中学生实践能... 详细信息

建国之初的17年里,学校教育在培养学生实践能力方面形成了一些基本模式,如校内模式、校外模式和半工半读模式等。这些基本模式是对比较充足的、翔实的教育实践历史资料进行了全面、深入的研究而概括出来的,对当代素质教育中学生实践能力的培养具有重要实践价值。

关键词：建国后17年学校教育实践能力基本模式启示

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佛教与现代法律的关系

西安交通大学学报（社会科学版） 2010年第2期30卷 80-84页

作者：马治国西安交通大学法学院陕西西安710049

佛法无边、世法有界体现的是无为法和有为法的差别。佛法教化众生向善,达到解脱、觉悟,实现佛国净土;世法规范世人言行,达到尊规、守法,维护社会秩序。虽然是两个不同的知识体系,但追求目标异中有同,本质上都属于行为规范,基本价值都是... 详细信息

佛法无边、世法有界体现的是无为法和有为法的差别。佛法教化众生向善,达到解脱、觉悟,实现佛国净土;世法规范世人言行,达到尊规、守法,维护社会秩序。虽然是两个不同的知识体系,但追求目标异中有同,本质上都属于行为规范,基本价值都是追求向善,而且无论是佛法还是世法,都在人类世界共行,适用对象在很大范围相同。佛教是对人的至高境界的追求,法律是对人的行为底线的设置。所以,佛教和现代法律之间其实存在着不解之缘,相互影响、相互借鉴、相互尊重,世出世间,共同发展。

关键词：佛教现代法律法律制度

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软件最终用户侵权的刑事责任

西安交通大学学报（社会科学版） 2006年第5期26卷 10-18页

作者：马治国西安交通大学知识产权研究中心陕西西安710049

针对目前社会上侵权盗版猖獗,法律发挥的效用却很有限的现状,认为最终用户或者称为消费者——一类特殊的侵犯主体,他们在市场中一方面是上帝,只有权利没有义务,另一方面却是软件侵权的最终完成人；如何处理二者关系,使得软件这种特殊的... 详细信息

针对目前社会上侵权盗版猖獗,法律发挥的效用却很有限的现状,认为最终用户或者称为消费者——一类特殊的侵犯主体,他们在市场中一方面是上帝,只有权利没有义务,另一方面却是软件侵权的最终完成人；如何处理二者关系,使得软件这种特殊的技术产品的知识产权既得到保护．又不侵害消费者的权益；而软件侵权的民事责任问题已经基本清楚,但是由于不足以威慑侵权人,所以追究刑事责任就成为软件业的期望；指出中国大陆目前尚不完全具备对最终用户侵权追究刑事责任的条件,只能逐步有条件地过渡到对最终用户承担刑事责任。

关键词：知识产权软件最终用户刑事责任