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AgInS_(2)/ZnS quantum dots for noninvasive cervical cancer screening with intracellular pH sensing using fluorescence lifetime imaging microscopy

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Nano Research 2022年第6期15卷 5193-5204页

作者： Wenhua Su Dan Yang Yulan wang Yawei Kong Wanlu Zhang Jing wang Yiyan Fei Ruiqian Guo Jiong ma Lan Mi Department of Optical Science and engineering Shanghai Engineering Research Center of Ultra-precision Optical ManufacturingKey Laboratory of Micro and Nano Photonic Structures(Ministry of Education)School of Information Science and TechnologyFudan UniversityShanghai 200433China Institute for Electric Light Sources School of Information Science and TechnologyFudan UniversityShanghai 200433China Department of Gynecology and Obstetrics The Central Hospital of WuhanTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430014China Institute of Photonic Chips University of Shanghai for Science and TechnologyShanghai 200093China Centre for Artificial-Intelligence NanophotonicsSchool of Optical-Electrical and Computer EngineeringUniversity of Shanghai for Science and TechnologyShanghai 200093China Institute of Biomedical engineering and Technology Academy for Engineer and TechnologyFudan University220 Handan RoadShanghai 200433China Shanghai engineering Research Center of Industrial Microorganisms the Multiscale Research Institute of Complex Systems(MRICS)School of Life SciencesFudan University220 Handan RoadShanghai 200433China

Intracellular pH plays a critical role in biological functions,and abnormal pH values are related to various ***,we report on an intracellular pH sensor AgInS_(2)(AIS)/ZnS quantum dots(QDs)that show long fluorescence lifetimes of hundreds of nanoseconds and low *** lifetime imaging microscopy(FLIM)combined with AIS/ZnS QDs is used for the imaging of live cells in different pH buffers and different cell *** FLIM images of AIS/ZnS QDs in live cells demonstrate different intracellular pH values in different regions,such as in lysosomes or *** method can also distinguish cancer cells from normal cells,and the fluorescence lifetime difference of the AIS/ZnS QDs between the two types of cells is 100±7 *** importantly,the exfoliated cervical cells from 20 patients are investigated using FLIM combined with AIS/ZnS *** lifetime difference value between the normal and cervical cancer(CC)groups is 115±9 ns,and the difference between the normal and the precancerous lesion group is 64±9 *** the first time,the noninvasive method has been used for cervical cancer screening,and it has shown great improvement in sensitivity compared with a clinical conventional cytology examination.

关键词： AIS/ZnS quantum dots fluorescence lifetime imaging microscopy intracellular pH sensing cervical cancer screening noninvasive

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基于轨道角动量谱分解的多通道水声通信及系统实现

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南京师大学报（自然科学版） 2024年第1期47卷 103-110页

作者：开诚治刘天颀王青东李禹志郭各朴马青玉南京师范大学计算机与电子信息学院/人工智能学院江苏南京210023 山东科技大学海洋工程学院山东青岛266590

水声通信能够实现信息的长距离传输,在深海探索和军事领域发挥重要作用.然而,由于换能器带宽和声波波长的影响,水声通信的发展与应用受到传输衰减大和信道容量低以及频谱利用率不足的限制.本文结合复用涡旋声束(AV)和轨道角动量(OAM)谱... 详细信息

水声通信能够实现信息的长距离传输,在深海探索和军事领域发挥重要作用.然而,由于换能器带宽和声波波长的影响,水声通信的发展与应用受到传输衰减大和信道容量低以及频谱利用率不足的限制.本文结合复用涡旋声束(AV)和轨道角动量(OAM)谱分解技术,研究了基于环形收发阵列的多通道水声通信方法,并系统实现.基于发送数据的ASCII编码,利用全息信号的幅度和相位调制,驱动环形换能器阵列发射沿轴传输的多通道OAM复用涡旋声束,并通过环形换能器阵列的信号采样和OAM谱分解完成复用涡旋声束的OAM模态解码,实现了高效的并行数据传输.构建了8声源环形收发阵列和全息相控系统,开展了6通道水声通信研究,成功实现了复用涡旋声场的实验测量和OAM解码,并与传统单通道二进制串行数据通信进行性能比较.理论和实验结果证明,基于OAM谱分解的通信通道数由发射阵列的阵元数N决定,其解码精度由发射信号的相位精度和接收阵列的阵元数决定;阵元数N≥1的大阵列系统在满OAM模式复用条件下的传输速率约为传统水声通信的N倍.本研究表明基于OAM谱分解的多通道通信可大幅提高信道容量和频谱利用率,为其在水声通信中的实际应用提供了一种实用方案.

关键词：多通道水声通信轨道角动量复用环形收发阵列全息信号谱分解

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malicious Code Modeling and Analysis in Weighted Scale-Free Networks

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Wuhan university Journal of Natural Sciences 2007年第1期12卷 51-54页

作者： wang Changguang wang Fangwei ZHANG Yangkai ma Jianfengi School of computer Xidian University Xi＇an 710071 ShaanxiChina college of Physics and information engineering Hebei NormalUniversity Shijiazhuang 050016 Hebei China Network Center Hebei Normal University Shijiazhuang 050016Hebei China

We study the detailed malicious code propagating process in scale-free networks with link weights that denotes traffic between two nodes. It is found that the propagating velocity reaches a peak rapidly then decays in a power-law form, which is different from the well-known result in unweighted network case. Simulation results show that the nodes with larger strength are preferential to be infected, but the hierarchical dynamics are not clearly found. The simulation results also show that larger dispersion of weight of networks leads to slower propagating, which indicates that malicious code propagates more quickly in unweighted scale-free networks than in weighted scale-free networks under the same condition. These results show that not only the topology of networks but also the link weights affect the malicious propagating process.

关键词： malicious code weighted scale-free networks propagation model

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Self-adaptive resource allocation for cloud-based software services based on progressive QoS prediction model

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Science china(information Sciences) 2019年第11期62卷 192-194页

作者： Xing CHEN Junxin LIN Yun ma Bing LIN Haijiang wang Gang HUANG college of mathematics and computer Science Fuzhou University Fujian Key Laboratory of Network Computing and Intelligent information Processing Fuzhou University School of Software Tsinghua University college of Physics and Energy Fujian Normal University Key Laboratory of High Confidence Software Technologies Ministry of Education

Dear editor,Self-adaptation is a promising approach to allocate resources for cloud-based software services [1, 2].Traditional self-adaptive resource-allocation methods are rule-driven, which leads to high administrat... 详细信息

关键词： service Self-adaptive resource allocation for cloud-based software services based on progressive QoS prediction model

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Community detection with attributed random walk via seed replacement

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Frontiers of computer Science 2022年第5期16卷 45-56页

作者： Yang CHANG Huifang ma liang CHANG Zhixin LI college of computer Science and engineering Northwest Normal UniversityLanzhou 730070China Guangxi Key Lab of Multi-source information Mining and Security Guangxi Normal UniversityGuilin 541004China Guangxi Key Laboratory of Trusted Software Guilin University of Electronic TechnologyGuilin 541004China

Community detection methods based on random walks are widely adopted in various network analysis *** could capture structures and attributed information while alleviating the issues of *** random walks on plain networks have been studied before,in real-world networks,nodes are often not pure vertices,but own different characteristics,described by the rich set of data associated with *** node attributes contain plentiful information that often complements the network,and bring opportunities to the random-walk-based ***,node attributes make the node interactions more complicated and are heterogeneous with respect to topological ***,attributed community detection based on random walk is challenging as it requires joint modelling of graph structures and node *** bridge this gap,we propose a Community detection with Attributed random walk via Seed replacement(CAS).Our model is able to conquer the limitation of directly utilize the original network topology and ignore the attribute *** particular,the algorithm consists of four stages to better identify communities.(1)Select initial seed nodes in the network;(2)Capture the better-quality seed replacement path set;(3)Generate the structure-attribute interaction transition matrix and perform the colored random walk;(4)Utilize the parallel conductance to expand the *** on synthetic and real-world networks demonstrate the effectiveness of CAS.

关键词： community detection seeds colored random walk parallel conductance

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基于J2EE的高校教育服务学生满意度调查系统的实现

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新疆师范大学学报（自然科学版） 2011年第4期30卷 109-113页

作者：杨婷婷马致明杨丽丽新疆师范大学计算机科学技术学院新疆乌鲁木齐830054

现代信息技术和互联网的飞速发展,极大提高了人类的生产效率,也为解决高校教育服务学生满意度调查的难题提供了良好的网络解决方案。本系统采用J2EE框架并结合JAVA插件设计完成,实际应用表明本系统可通过网络调查为高校获取各种学生满... 详细信息

现代信息技术和互联网的飞速发展,极大提高了人类的生产效率,也为解决高校教育服务学生满意度调查的难题提供了良好的网络解决方案。本系统采用J2EE框架并结合JAVA插件设计完成,实际应用表明本系统可通过网络调查为高校获取各种学生满意度信息,从而为学校的发展提供必要的数据参考和决策依据。文中对系统的体系结构、系统中的类及系统功能模块的实现过程和部分关健代码做了详细的介绍。

关键词： J2EE 系统体系结构高等教育满意度调查系统

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基于边缘信息增强的前列腺MR图像分割网络

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中国图象图形学报 2024年第3期29卷 755-767页

作者：张蝶黄慧马燕黄丙仓陆炜平上海师范大学信息与机电工程学院上海201400 上海市浦东新区公利医院影像科上海200120

目的前列腺图像精确分割对评估患者健康和制定治疗方案至关重要。然而传统U-Net模型在前列腺MR(magnetic resonance)图像分割上存在过拟合、边缘信息丢失等问题。针对上述问题,提出一种改进的U-Net 2D分割模型,旨在增强边缘信息、降低... 详细信息

目的前列腺图像精确分割对评估患者健康和制定治疗方案至关重要。然而传统U-Net模型在前列腺MR(magnetic resonance)图像分割上存在过拟合、边缘信息丢失等问题。针对上述问题,提出一种改进的U-Net 2D分割模型,旨在增强边缘信息、降低噪声影响,进而提高前列腺分割效果。方法为缓解过拟合现象,新模型通过对标准U-Net架构进行修改,将普通卷积替换为深度可分离卷积,重新设计编码器和解码器结构,降低模型参数量;为保存分割结果中的边缘信息,新模型通过ECA(efficient channel attention)注意力机制对U-Net解码器特征进行优化,以放大并保存小尺度目标的信息,并提出边缘信息模块和边缘信息金字塔模块,恢复并增强边缘信息,以缓解频繁下采样带来的边缘信息衰退以及编码器和解码器特征之间的语义差距问题;利用空洞空间金字塔池化(atrous spatial pyramid pooling,ASPP)模块对特征进行重采样,扩大感受野,以消除特征噪声。结果在PROMISE12(prostate MR image segmentation 2012)数据集上验证模型的有效性,并与6种基于U-Net的图像分割方法进行对比,实验证明其分割结果在Dice系数(Dice coefficient,DC)、HD95(95%Hausdorff distance)、召回率(recall)、Jaccard系数和准确度(accuracy)等指标上均有提高,DC较U-Net提高了8.87%,HD95较U-Net++和Attention U-Net分别降低了12.04 mm和3.03 mm。结论提出一种基于边缘信息增强的前列腺MR图像分割网络(attention mechanism and marginal information fusion U-Net,AIM-U-Net),其生成的分割图像具有丰富的边缘信息和空间信息,其主观效果和客观评价指标均优于其他同类方法,为提高临床诊断的准确度提供帮助。

关键词：医学图像分割前列腺 MR图像 U-Net 边缘信息

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Stability evaluation for steep bank slope with microseismic monitoring in Three Gorges Reservoir area

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Journal of Mountain Science 2022年第6期19卷 1588-1601页

作者： XIE Qing-ming LONG Kui LI Zi-mu CHEN Li-chuan LIU Hong XU Hong HE Fei liang Dan XIANG Xue-kun ma Qiang Chongqing college of Electronic engineering Chongqing 401331China Technology Innovation Center of Geohazards Automatic Monitoring Ministry of Natural ResourcesChongqing Institute of Geology and Mineral ResourcesChongqing 401120China college of computer and information Science college of Software Southwest UniversityChongqing 400715China Chongqing Rail Transit Design and Research Institute Chongqing 401122China

Rock slide is one of the common geohazard in the Three Gorges Reservoir area, and it affects the shipping of the Yangtze River and the safety of people living on the banks. In order to investigate the internal fracturing mechanism of rock mass, distributed microseismic monitoring network was arranged with 15 three component geophones(3C geophones), deployed at borehole and out of the sliding mass in the unstable Dulong slope. Stein Unbiased Risk Estimation(SURE) method was used to noise suppression for the microseismic record, and decomposition parameters of the Continuous Wavelet Transform(CWT) were determined with maximum energy of correlation coefficient(MECC) method. The signal-to-noise ratio was tripled after the process, and source parameters are obtained with full waveform inversion. The rupture volume model was counted by the irregular grid statistics with the events’ density. It shows that the rock slide is of a small scale and composed of a single block. Moreover, the relationship among microseismicity, displacement and rainfall were discussed in the paper. The deformation rate was dramatically changed in the period of intensive events. There is a good consistency especially in the rainfall period. Although there is a time delay, continuous rainfall is more likely to cause the increase of microseismic events. The results show that the Dulong slope is a shallow rock slide in the state of creep deformation, and the rupture mechanism of the rock mass is left-lateral normal fault with shear failure. The research provides more key information for the early warning and prevention of rock slides and helps to reduce the risk of geohazards.

关键词： Stability evaluation Microseismic monitoring Rock slide Rainfall Displacement

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Beam alignments based on the spectrum decomposition of orbital angular momentums for acoustic-vortex communications

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Chinese Physics B 2022年第12期31卷 296-304页

作者： Gepu Guo Xinjia Li Qingdong wang Yuzhi Li Qingyu ma Juan Tu Dong Zhang School of computer and Electronic information Nanjing Normal UniversityNanjing 210023China Haiying Enterprise Group Co. Ltd.Wuxi 214061China college of Ocean Science and engineering Shandong University of Science and TechnologyQingdao 266590China Institute of Acoustics Nanjing UniversityNanjing 210093China

Given the enhanced channel capacity of wave chirality,acoustic communications based on the orbital angular momentum(OAM)of acoustic-vortex(AV)beams are of significant interest for underwater data ***,the stringent beam alignment is required for the coaxial arrangement of transceiver arrays to ensure the accuracy and reliability of OAM *** avoid the required multiple measurements of the traditional orthogonality based algorithm,the beam alignment algorithm based on the OAM spectrum decomposition is proposed for AV communications by using simplified *** studies of the single-OAM and OAM-multiplexed AV beams show that the error of the OAM spectrum increases with the translation distance and the deflection angle of the transceiver *** achieve an ideal arrangement,two methods of the single-array translation alignment and the dual-array deflection alignment are developed based on the least standard deviation of the OAM spectrum(SD-OAM).By decreasing the SD-OAM towards zero using transceiver arrays of 16 transmitters and 16 receivers,accurate beam alignments are accomplished by multiple adjustments in three *** proposed method is also demonstrated by experimental measurements of the OAM dispersion and the SD-OAM for misaligned *** results demonstrate the feasibility of the rapid beam alignment based on the OAM spectrum decomposition by using simplified transceiver ring-arrays,and suggest more application potentials for acoustic communications.

关键词： acoustic-vortex beam beam alignment orbital angular momentum(OAM)spectrum least standard deviation acoustic communication

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基于层次聚类的三维点云特征点检测算法

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应用激光 2024年第4期44卷 164-170页

作者：马学磊薛河儒周艳青内蒙古农业大学计算机与信息工程学院内蒙古呼和浩特010018

针对传统方法对点云中的细节特征不能准确检测,无法反映物体的真实信息的问题,提出了一种基于层次聚类算法的点云特征点检测方法。使用最小生成树结合深度优先遍历算法,对点云中各点与其邻域点所形成三角形的法向量方向进行调整;使用法... 详细信息

针对传统方法对点云中的细节特征不能准确检测,无法反映物体的真实信息的问题,提出了一种基于层次聚类算法的点云特征点检测方法。使用最小生成树结合深度优先遍历算法,对点云中各点与其邻域点所形成三角形的法向量方向进行调整;使用法向量的高斯隐射检测出点云模型中的非特征点和候选特征点;对于候选特征点使用层次聚类算法判断其是否为特征点。试验结果表明,基于层次聚类的点云特征点检测算法可准确地检测出散乱点云数据中位于特征区域内的特征点,对细节不明显的特征点也可进行有效检测。研究方法对Sheep、Fandisk、Bunny和Dragon 4种点云模型检测的特征点数量分别为810、933、2 955、3 941个,多于其他特征点检测方法。

关键词：点云特征检测高斯隐射层次聚类

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