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Epidemic Characteristics and Spatio-Temporal patterns of HFrS in Qingdao City,china,2010-2022

第二十九届中国控制会议

作者： ma ming-da,zeng xian-lin,duan guang-ren center for control and guidance technology,harbin institute of technology,harbin 150001,p.r.china

This paper consider the minimum fuel two-impulse orbital transfer between coplanar *** transfer orbit is parameterized in terms of the eccentricity vector component in the direction perpendicular to the chord connecting the two *** total increment of the velocity is expressed as a function of the transverse *** proposed method accommodates for both circular orbits and elliptic orbits and it does not have the limitations that the apsidal lines must be *** is proved that Hohmann transfer is a special case of the proposed method when the transfer angle is 180 *** simulation example is given to show the effectiveness of the proposed method.

关键词： Optimal orbital transfer Impulsive transfer Minimum-fuel

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Biomedical and Environmental Sciences 2024年第9期37卷 1015-1029页

作者： Ying Li runze Lu Liyan Dong Litao Sun Zongyi Zhang Yating Zhao Qing duan Lijie Zhang Fachun Jiang Jing Jia Huilai ma Chinese Field Epidemiology Training program Chinese Center for Disease Control and PreventionBeijing 100050China National institute for Viral Disease control and prevention Chinese Center for Disease Control and PreventionBeijing 102206China Qingdao Municipal center for Disease control and prevention Qingdao 266024ShandongChina Jiaozhou center for Disease control and prevention Qingdao 266399ShandongChina institute for Infectious Disease control and prevention Shandong Center for Disease Control and PreventionJinan 250013ShandongChina Office of Epidemiology(Technical guidance Office for patriotic Health Work) Chinese Center for Disease Control and PreventionBeijing 102206China

Objective This study investigated the epidemic characteristics and spatio-temporal dynamics of hemorrhagic fever with renal syndrome(HFrS)in Qingdao City,*** Information was collected on HFrS cases in Qingdao City from 2010 to *** epidemiologic,seasonal decomposition,spatial autocorrelation,and spatio-temporal cluster analyses were *** A total of 2,220 patients with HFrS were reported over the study period,with an average annual incidence of 1.89/100,000 and a case fatality rate of 2.52%.The male:female ratio was 2.8:1.75.3%of patients were aged between 16 and 60 years old,75.3%of patients were farmers,and 11.6%had both“three red”and“three pain”*** HFrS epidemic showed two-peak seasonality:the primary fall-winter peak and the minor spring *** HFrS epidemic presented highly spatially heterogeneous,street/township-level hot spots that were mostly distributed in Huangdao,pingdu,and *** spatio-temporal cluster analysis revealed three cluster areas in Qingdao City that were located in the south of Huangdao District during the fall-winter *** The distribution of HFrS in Qingdao exhibited periodic,seasonal,and regional characteristics,with high spatial clustering *** typical symptoms of“three red”and“three pain”in patients with HFrS were not obvious.

关键词： Hemorrhagic fever with renal syndrome Epidemic characteristics Spatio-temporal distribution

Adaptive Dynamic Surface control for Integrated Missile guidance and Autopilot

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International Journal of Automation and computing 2011年第1期8卷 122-127页

作者： ming-Zhe Hou guang-ren duan center for control Theory and guidance technology Harbin Institute of Technology Harbin 150001 PRC

Integrated guidance and control for homing missiles utilizing adaptive dynamic surface control approach is considered based on the three channels independence design idea. A time-varying integrated guidance and control model with unmatched uncertainties is first formulated for the pitch channel, and an adaptive dynamic surface control algorithm is further developed to deal with these unmatched uncertainties. It is proved that the proposed feedback controller can ensure not only the accuracy of target interception, but also the stability of the missile dynamics. Then, the same control approach is further applied to the control design of the yaw and roll channels. The 6-degree-of-freedom （6-DOF） nonlinear missile simulation results demonstrate the feasibility and advantage of the proposed integrated guidance and control design scheme.

关键词： Integrated guidance and control unmatched uncertainty adaptive control dynamic surface control homing missiles.

Output Feedback Stabilization of Switched Stochastic Nonlinear Systems Under Arbitrary Switchings

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International Journal of Automation and computing 2013年第6期10卷 571-577页

作者： Xiao-ling Liang ming-Zhe Hou guang-ren duan center for control Theory and guidance technology Harbin Institute of Technology

This paper is concerned with the problem of global output feedback stabilization in probability for a class of switched stochastic nonlinear systems under arbitrary switchings. The subsystems are assumed to be in output feedback form and driven by white noise. By introducing a common Lyapunov function, the common output feedback controller independent of switching signals is constructed based on the backstepping approach. It is proved that the zero solution of the closed-loop system is fourth-moment exponentially stable. An example is given to show the effectiveness of the proposed method.

关键词： Stochastic nonlinear system switched nonlinear system output feedback under arbitrary switchings moment expo-nential stability.

Adaptive fuzzy backstepping control for attitude stabilization of flexible spacecraft with signal quantization and actuator faults

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Science china(Information Sciences) 2021年第5期64卷 135-150页

作者： Qiuhong LIU ming LIU guangren duan research institute of Intelligent control Systems Harbin Institute of Technology research center of Satellite technology Harbin Institute of Technology center for control Theory and guidance technology Harbin Institute of Technology

In this study, the fault-tolerant attitude control of flexible spacecraft is investigated over digital communication channels, where a uniform quantizer is considered with respect to the sensor signals and controller indexes. Further, an adaptive fuzzy backstepping control strategy has been developed for the considered attitude stabilization issue, where the adaptive fuzzy logic method is used to approximate the rigid-flexible coupled nonlinearity of the spacecraft. In this design, the online adjusting quantizer parameters are injected into the controller gains to simultaneously compensate for the quantization errors and timevarying actuator faults. In the proposed control method, the attitude stabilization task is achieved in the presence of external disturbances, time-varying actuator faults, and signal quantization. Finally, the practical examples are compared to demonstrate the effectiveness of the proposed control strategy.

关键词： fault-tolerant control attitude stabilization signal quantization adaptive fuzzy control backstepping control

Fault diagnosis of control moment gyroscope based on a new CNN scheme using attention-enhanced convolutional block

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Science china(Technological Sciences) 2022年第11期65卷 2605-2616页

作者： ZHAO HaoTian LIU ming SUN YiYong CHEN Zhang duan guangren CAO XiBin research center of Satellite technology School of AstronauticsHarbin Institute of TechnologyHarbin 150001China School of Aerospace Engineering Beijing Institute of TechnologyBeijing 100081China Department of Automation TsinghuaUniversityBeijing 100084China control Theory and guidance technology School of AstronauticsHarbin Institute of TechnologyHarbin150001China

control moment gyroscope(CMG)is a typical attitude control system component for satellites and mobile robots,and the online fault diagnosis of CMG is crucial because it determines the stability and accuracy of the attitude control *** paper develops a data-driven CMG fault diagnosis scheme based on a new CNN *** this design,seven types of fault signals are converted into spectrum datasets through short-time Fourier transformation(STFT),and a new CNN network scheme called AECB-CNN is proposed based on attention-enhanced convolutional blocks(AECB).AECB-CNN can achieve high training accuracy for the CMG fault diagnosis datasets under different sliding window ***,simulation results indicate that the proposed fault diagnosis method can achieve an accuracy of nearly 95%in 1.28 s and 100%in 2.56 s,respectively.

关键词： fault diagnosis control moment gyroscope CNN scheme attention-enhanced convolutional block

A model validation method based on the orthogonal polynomial transformation and area metric

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International Journal of Modeling, Simulation, and Scientific Computing 2022年第2期13卷 215-232页

作者： Huan Zhang Wei Li ping ma ming Yang control and Simulation center harbin institute of technology harbin P.R.China

Modeling and Simulation technology has become an important means to study various complex systems with its extensive ***,the accuracy of the simulation models becomes a critical problem and needs to be assessed by employing an appropri-ate model validation *** simulation models often have multivariate dynamic responses with uncertainty,while most of the existing validation methods concentrate on the validation of the static ***,a new validation method is proposed in this paper to validate the dynamic responses of the simulation models over the time domain at a single validation site and multiple validation sites through introducing the discrete Chebyshev polynomials and area *** each time series,the orthogonal expan-sion coefficients are extracted primarily by representing the time series with the discrete orthogonal ***,the area metric and the u-pooling metric are employed to validate all the uncorrelated coefficients at a single validation site and multiple vali-dation sites,respectively,and the final validation result is obtained by summarizing the metric *** feasibility and effectiveness of the proposed model validation method are illustrated through the example of the terminal guidance stage of the flight vehicle.

关键词： Model validation dynamic response uncertainty orthogonal polynomial area metric

Single-cell immune profiling reveals distinct immune response in asymptomatic COVID-19 patients

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Signal Transduction and Targeted Therapy 2021年第10期6卷 3108-3118页

作者： xiang-Na Zhao Yue You Xiao-ming Cui Hui-Xia Gao Guo-lin Wang Sheng-Bo Zhang lin Yao Li-Jun duan Ka-Li Zhu Yu-ling Wang Li Li Jian-Hua Lu Hai-Bin Wang Jing-Fang Fan Huan-Wei Zheng Er-Hei dai Lu-Yi Tian mai-Juan ma center for Disease control and prevention of Chinese people's Liberation Army BeijingChina The Walter and Eliza Hall institute of Medical research ParkvilleVicAustralia Department of Medical Biology The University of MelbourneParkvilleVicAustralia State Key Laboratory of pathogen and Biosecurity Beijing Institute of Microbiology and EpidemiologyBeijingChina The Fifth Hospital of Shijiazhuang Hebei Medical UniversityShijiazhuangChina

While some individuals infected by severe acute respiratory syndrome coronavirus 2(SArS-CoV-2)present mild-to-severe disease,many SArS-CoV-2-infected individuals are *** sought to identify the distinction of immune response between asymptomatic and moderate *** performed single-cell transcriptome and T-cell/B-cell receptor(TCr/BCr)sequencing in 37 longitudinal collected peripheral blood mononuclear cell samples from asymptomatic,moderate,and severe patients with healthy *** patients displayed increased CD56^(bri)CD16^(-) natural killer(NK)cells and upregulation of interferon-gamma in effector CD4^(+) and CD8^(+) T cells and NK *** showed more robust TCr clonal expansion,especially in effector CD4^(+) T cells,but lack strong BCr clonal expansion compared to moderate ***,asymptomatic patients have lower interferon-stimulated genes(ISGs)expression in general but large interpatient variability,whereas moderate patients showed various magnitude and temporal dynamics of the ISGs expression across multiple cell populations but lower than a patient with severe *** data provide evidenee of different immune signatures to SArS-CoV-2 in asymptomatic infections.

关键词： patients asymptomatic interferon

Efficacy and safety of Shenyankangfu Tablet,a Chinese patent medicine,for primary glomerulonephritis:A multicenter randomized controlled trial

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Journal of Integrative Medicine 2021年第2期19卷 111-119页

作者： Jie Wu Shu-wei duan Hong-tao Yang Yue-yi Deng Wei Li Ya-ni He Zhao-hui Ni Yong-li Zhan Shan lin Zhi-yong Guo Jun Zhu Jing-ai Fang Xu-sheng Liu Li-hua Wang rong Wang Nian-song Wang Xiao-hong Cheng Li-qun He ping Luo Shi-ren Sun Ji-feng Sun Ai-ping Yin Geng-ru Jiang Hong-yu Chen Wen-hu Liu Hong-li lin Meng Liang Lu ma ming Chen Li-qun Song Jian Chen Qing Zhu Chang-ying Xing Yun Li Ji-ning Gao rong-shan Li Ying Li Hao Zhang Ying Lu Qiao-ling Zhou Jun-zhou Fu Qiang He guang-yan Cai xiang-mei Chen Department of Nephrology Chinese People’s Liberation Army General HospitalChinese People’s Liberation Army Institute of NephrologyState Key Laboratory of Kidney Diseases(2011DAV00088)National Clinical Research Center for Kidney DiseasesBeijing 100853China Department of Nephrology First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300192China Department of Nephrology Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China Department of Nephrology Shandong University of Traditional Chinese Medicine Affiliated HospitalJinan 250011.Shandong ProvinceChina Department of Nephrology Daping HospitalArmy Medical UniversityChongqing 400042China Department of Nephrology Renji HospitalShanghai Jiao Tong UniversityShanghai 200127China Department of Nephrology Guang’anmen HospitalChina Academy of Traditional Chinese Medical SciencesBeijing 100053China Department of Nephrology Tianjin Medical University General HospitalTianjin 300052China Department of Nephrology Changhai Hospital of ShanghaiNaval Medical UniversityShanghai 200433China Department of Nephrology West China HospitalChengdu 610083Sichuan ProvinceChina Department of Nephrology First Affiliated Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Nephrology Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Department of Nephrology Shanxi Medical University Second Affiliated HospitalTaiyuan 030001Shanxi ProvinceChina Department of Nephrology Shandong Provincial HospitalJinan 250021Shandong ProvinceChina Department of Nephrology and rheumatology Affiliated Sixth People’s HospitalShanghai Jiao Tong UniversityShanghai 200233China Department of Nephrology Shaanxi Traditional Chinese Medicine HospitalXi'an 710003Shaanxi ProvinceChina Department of Nephrology Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghai 200021China Department of Nephrology Jilin University Se

Background:Shenyankangfu Tablet(SYKFT)is a Chinese patent medicine that has been used widely to decrease proteinuria and the progression of chronic kidney ***:This trial compared the efficacy and safety of SYKFT,for the control of proteinuria in primary glomerulonephritis patients,against the standard drug,losartan ***,setting,participants and intervention:This was a multicenter,double-blind,randomized,controlled clinical *** glomerulonephritis patients,aged 18-70 years,with blood pressure≤140/90 mmHg,estimated glomerular filtration rate(eGFr)>45 mL/min per 1.73 ㎡,and 24-hour proteinuria level of 0.5-3.0 g,were recruited in 41 hospitals across 19 provinces in china and were randomly divided into five groups:SYKFT,losartan potassium 50 mg or 100 mg,SYKFT plus losartan potassium 50 mg or 100 *** outcome measu res:The primary outcome was change in the 24-hour proteinuria level,after 48 weeks of ***:A total of 735 participants were *** percent decline of urine protein quantification in the SYKFT group after 48 weeks was 8.78%±2.56%(p=0.006)more than that in the losartan 50 mg group,which was 0.51%±2.54%(p=1.000)less than that in the losartan 100 mg *** with the losartan potassium 50 mg group,the SYKFT plus losartan potassium 50 mg group had a 13.39%±2.49%(preater reduction in urine protein *** with the losartan potassium 100 mg group,the SYKFT plus losartan potassium 100 mg group had a 9.77%±2.52%(p=0.001)greater reduction in urine *** a superiority threshold of 15%,neither was statistically ***,serum creatinine and serum albumin from the baseline did not change statistically *** average change in TCM syndrome score between the patients who took SYKFT(-3.00[-6.00,-2.00])and who did not take SYKFT(-2.00[-5.00,0])was statistically significant(p=0.003).No obvious adverse reactions were observed in any ***:SYKFT decreased the proteinur

关键词： Herbal medicine,Chinese Shenyankangfu Tablet primary glomerulonephritis randomized controlled trial Double blind Double dummy