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Pulmonary vein tachycardia after pulmonary vein isolation in patients with atrial fibrillation

Chinese Medical Journal 2006年第7期119卷 551-556页

作者： ma chang-shen dong jian-zeng liu xing-peng long de-yong fang dong-ping hu fu-li yu rong-hui tang ri-bo hao peng lu chun-shan department of Cardiology Beijing Anzhen Hospital CapitalUniversity of Medical Sciences Beijing 100029 China

Background Pulmonary vein （PV） isolation has been developed to treat patients with atrial fibrillation （AF）, and the electrophysiological endpoint of PV isolation is the disappearance or dissociation of pulmonary vein potentials （PVPs）. Pulmonary vein tachycardia （PVT） is the dissociated PV rhythm with a rapid rate. However, the characteristics and significance of PVT after pulmonary vein isolation in patients with AF remains unclear. Methods From June 2003 to June 2005, a total of 285 consecutive patients with drug refractory AF were included in this study, and they underwent segmental pulmonary vein ablation （SPVA） or circumferential pulmonary vein ablation （CPVA）. PV isolation was the initial endpoint for both approaches with documenting disappearance or dissociation of PVPs. PVT was characterized as dissociated activities within PVs with a circle length （CL） of 〈300 ms, and was classified into organized PVT or disorganized PVT according to the variance of CL. Systematic follow-up was conducted after initial procedures. Continuous variables were analyzed by Student＇s t test and categorical variables were analyzed by chi-square test. Results Three hundred and fifteen PVs were ablated in 85 patients underwent SPVA approach, 400 circular lesions surrounding ipsilateral PVs （including 790 PVs） were produced in the rest of 200 patients received CPVA approach. Electrical isolation was achieved in all of these PVs. Of these, PVPs were abolished in 89.8% （992/1105） of the ablated PVs, dissociated PV rhythms were documented in the rest 10.2 % （113/1105） of the treated PVs. Among the 113 dissociated PV rhythms, 28 met the criteria of PVT with mean CL of （155±43） ms （2 PYTs in 2 patients received SPYA, 26 PYTs in 18 patients underwent CPVA）. PVT was more frequently documented in patients underwent CPVA approach [9.0% （18/200） vs 2.3% （2/85）, P=0.04]. During the 6-month follow-up, it was indicated that no significant difference existed in AF free rate between patients wi

关键词： atrial fibrillation pulmonary vein tachycardia

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Transient ST-segment elevation after transseptal puncture for atrial fibrillation ablation in two cases

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Chinese Medical Journal 2012年第5期125卷 941-944页

作者： CHENG Yan-li dong jian-zeng liu xing-peng long de-yong fang dong-ping yu rong-hui tang ri-bo ma chang-sheng department of Cardiology Beijing An Zhen HospitalCapital Medical UniversityBeijing100029China

The present report demonstrates two cases of transient inferior ST-segment elevation accompanied by profound hypotension and bradycardia immediately after transseptal puncture for catheter ablation of atrial fibrillation. This rare complication of transseptal puncture was resolved quickly within several minutes. The most likely mechanism of this phenomenon is coronary vasospasm, although coronary embolism can not be ruled out completely. This complication is characterized as follows：（1） The right coronary artery might be the most likely involved vessel and therefore myocardial ischemia usually occurs in the inferior wall of left ventricular; （2） Reflex hypotension and bradycardia by the Bezold-Jarisch reflex secondary to inferior ischemia often occur at the same time. Though it appears to be a transient and completely reversible phenomenon, there are still potential life-threatening risks because of myocardial ischemia and profound haemodynamic instability. Clinical cardioloaists should be aware of this rare comolication and orooerlv deal with it.

关键词： ST-segment elevation transseptal puncture atrial fibrillation catheter ablation

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Unconscious sedation/analgesia with propofol versus conscious sedation with fentanyl/midazolam for catheter ablation of atrial fibrillation:a prospective,randomized study

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Chinese Medical Journal 2007年第22期120卷 2036-2038页

作者： tang ri-bo dong jian-zeng Zhao Wen-du liu xing-peng KANG Jun-ping long de-yong yu rong-hui hu fu-li liu Xiao-hui ma chang-sheng department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China department of Anesthesiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

Catheter ablation of atrial fibrillation （AF） has been ,increased dramatically recently. However, it is an unpleasant procedure with intolerable pain without sedation. Propofol and fentanyl/midazolam have been widely used in painful clinical examination and cardiovascular procedures with established safety and efficacy. Propofol, alfentanyl and midazolam were administrated for catheter ablation in some electrophysiological labs for a less painful procedure. However, there is few published work on the sedation regimen for catheter ablation of AF.

关键词： atrial fibrillation ablation sedation

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Late intra-atrial reentrant tachycardia would be prevented by ablation of right atrial potential isthmuses during the surgical operation for congenital heart disease

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Chinese Medical Journal 2010年第18期123卷 2613-2615页

作者： SANG Cai-hua dong jian-zeng liu xing-peng yu rong-hui long de-yong tang ri-bo ma chang-sheng department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

Intra-atrial reentrant tachycardia （IART） is not uncommon after surgical correction of congenital heart disease （CHD）. The patients with IART are often refractory to antiarrhymic agents and present with severe symptoms. Current treatment approach to IART has shifted largely to interventional procedures which have a good short-term success rate, however, late recurrence rate is still high. With the development of mapping technique especially the application of three-dimensional electroanatomic mapping,

关键词： congenital heart disease intra-atrial reentrant tachycardia prevention ablation

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Recurrent atrial tachycardia and atrial fribrillation after circumferential pulmonary vein ablation:What’s the difference?

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Chinese Medical Journal 2005年第21期118卷 1773-1778页

作者： liu xing-peng long de-yong dong jian-zeng liu Xiao-qing fang dong-ping hao peng ma chang-sheng department of Cardiology Beijing Anzhen Hospital Capital University of Medical Science Beijing 100029 China

Background Recurrent atrial tachyarrhythmia （ATa） after circumferential pulmonary vein ablation （CPVA） includes atrial tachycardia （AT） and atrial fribrillation （AF）. However, whether there are some differences in clinical course and mechanisms between the recurrent AT and the recurrent AF remained unclear. This study was conducted to investigate the incidence, mechanism, clinical course of the recurrent AT and AF in patients under *** One hundred and thirty consecutive patients （M/F = 95/35 ） with highly symptomatic ano multiple antiarrhythmic drugs （AADs） refractory paroxysmal （ n = 91 ） or persistent （ n = 39 ） AF were included. The ablation protocol consisted solely of two continuous circular lesions around the ipsilateral pulmonary veins （PV） guided by CARTO system. The endpoint of CPVA is PV isolation. For patients with recurrent ATa within 2 months after the initial procedure, cardioversion with direct current was attempted if the ATa lasted for more than 24 hours. A repeat ablation procedure was performed only for patients with AADs refractory recurrent ATa and at least followed up for 2 months after the initial *** Within 2 months after the initial procedure, 52 patients （40. 0% ） had experienced episodes of symptomatic recurrent ATa. Among them, 23 patients （44.2%） with recurred AT alone （AT group ）, 14 patients （26.9%） with recurred AF alone （AF group）, and 15 patients （28.8%） with recurred AT and AF （AT plus AF group）. The delayed cure rate （65.2%） in AT group was significant higher than that in AF group （21.4%, P〈0.05） and AF plus AT group （26.7%, P 〈0.05）. A repeat ablation was performed in 21 patients, including 6 patients with recurrent AT alone, 8 patients with recurrent AF alone, and 7 patients with recurrent AF plus AT. The mean number of PV gaps was 1.2 ± 0. 4 in AT group, which was significantly lower than that in AF group （2.6 ± 0. 7, P 〈 0.05） and AF plus AT group （2.0 ± 0.6, P 〈 0.05）. delayed cure rate and number of PV

关键词： atrial fibrillation catheter ablation pulmonary vein

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Mechanisms of organized atrial tachycardia during catheter ablation of chronic atrial fibrillation by stepwise approach

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Chinese Medical Journal 2010年第7期123卷 852-856页

作者： NING man dong jian-zeng liu xing-peng yu rong-hui long de-yong tang ri-bo SANG Cai-hua ma chang-sheng department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

Background Extensive atrial fibrillation （AF） ablation is associated with an increased success rate of catheter ablation in chronic AF patients and an increased rate of atrial tachycardia （AT） during the procedure. The mechanism of these Ats varies in previous studies. Our study aimed to report the mechanism of organized AT occurring during the stepwise ablation procedure of chronic *** A prospective cohort of 86 consecutive patients who underwent an ablation procedure for chronic atrial fibrillation （CAF） was investigated. The stepwise procedure was performed in the following order： circumferential pulmonary vein ablation, complex fractionated atrial electrograms ablation, mapping and ablation of AT. The endpoint was noninducibility of AF/AT after sinus rhythm （SR） was restored or the procedure time was beyond 6 *** Sixty-nine （80%） of patients converted to SR via AT. A total of 179 sustained ATs were observed in 69 patients during the procedure. There were 81% （n=145） macroreentrant ATs which included 65 perimitral circuits, 48 peritricuspid tachycardia and 32 roof dependent circuits, 12% （n=21） localized reentrant and 7% （n=13） focal ATs. Thirty （15%） patients experienced significant left atrium （LA） and LA appendage （LAA） conduction delay or dissociation in the procedure or during the follow-up *** Most CAF patients converted to SR via ablation of organized AT occurring during the stepwise procedure. The mechanism of most of these ATs was macro-reentry.

关键词： organized atrial tachycardia chronic atrial fibrillation catheter ablation stepwise approach

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Image integration system to guide catheter ablation of atrial tachycardia with a multi-key-isthmus reentrant in a patient with a repaired atrial septal defect： a case report

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Chinese Medical Journal 2008年第9期121卷 859-861页

作者： yu rong-hui dong jian-zeng liu xing-peng long de-yong KANG Jun-ping ma chang-sheng department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

Recurrent atrial tachycardia （AT） is often observed late .after heart surgery and it contributes significantly to the morbidity and mortality of this group of patients. In patients with structurally normal hearts the most prevalent type of AT is a macroreentrant atrial tachycardia （maT）, more specifically known as common atrial flutter （AFL）. In contrast, in patients with repaired structural heart disease other ATs may occur due to the existence of variable and multiple arrhythmogenic substrates, related to the underlying heart disease and/or the surgical incisions.

关键词： integration catheter ablation atrial tachycardia atrial septal defect macroreentry

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Catheter ablation of persistent atrial fibrillation with and without a history of paroxysmal atrial fibrillation

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Chinese Medical Journal 2012年第6期125卷 1175-1178页

作者： MIAO Cheng-long YIN Xian-dong dong jian-zeng liu xing-peng yu rong-hui long de-yong tang ri-bo SANG Cai-hua ma chang-sheng department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China Beijing Chaoyang Hospital Capital Medical University Beijing 100020 China.

Background It is unclear whether a history of paroxysmal atrial fibrillation （PAF） would impact the effect of catheter ablation on persistent atrial fibrillation （AF）. This study aimed to compare the effect of catheter ablation on persistent AF with and without a history of PAF. Methods One hundred and eighty-three patients underwent catheter ablation of persistent AF lasting for 〉1 month and were reviewed. Patients were divided into two groups according to whether they had a history of PAF or not. Group I consisted of persistent AF patients with a history of PAF, and group II consisted of persistent AF patients without such a history. All patients received catheter ablation focused on pulmonary vein isolation and were observed for arrhythmia recurrences, which were defined as documented episodes of AF or atrial tachycardia after a blanking period of 3 months. Results One hundred and three patients （60.9%） in group I and sixty-six patients （39.1%） in group II were successfully followed and included in analysis. There were no significant differences in clinical and echocardiographic characteristics between both groups except for a younger age and more male patients in group II. After （15.5±10.7） months of follow-up, 59 （57.3%） patients in group I and 49 （74.2%） patients in group II maintained sinus rhythm free of anti-arrhythmia drugs （P=0.025）. Multivariate analyses found left atrial anteroposterior diameter （P=0.006） and persistent AF with a history of PAF （OR 1.792, 95% CI 1.019-3.152; P=0.043） as the only independent statistical predictors of arrhythmia recurrences. Conclusion The arrhythmia recurrence rate of catheter ablation based on pulmonary vein isolation in persistent AF with a history of PAF was hiQher than those without a history of PAF

关键词： atrial fibrillation radiofrequency ablation recurrence

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CEPC Technical design Report

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Radiation detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade yong Ban Tripamo Bandyopadhyay Shou-shan Bao desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili deng Binglin denis bodrov Anton bogomyagkov Serge bondarenko Stewart boogert maarten boonekamp marcello borri Angelo bosotti Vincent boudry Mohammed boukidi Igor boyko Ivanka bozovic Giuseppe bozzi Jean-Claude Brient Anastasiia Budzinskaya masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao jianshe Cao Antoine Chance Xuejun chang yue chang Zhe chang Xinyuan chang Wei Chao Auttakit Chatrabhuti Yimin Che yuzhi Che Bin Chen Danping Chen fuqing Chen fusan Chen Gang Chen Guoming Chen hua-xing Chen huirun Chen Jinhui Chen Ji-yuan Chen Kai Chen mali Chen Mingjun Chen Mingshui Chen Ning Chen shanhong Chen shanzhen Chen Shao-long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen yukai Chen Zelin Chen Zilin Chen Gang Chen boping Chen chunhui Chen Hok Chuen Cheng huajie Cheng shan Cheng Tongguang Cheng yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-yun Dai Xinchen Dai Xuwen Dai Antonio de maria Nicola de Filippis Christophe de La Taille Francesca de Mori Chiara de Sio Elisa del Core Shuangxue deng Wei-Tian deng Zhi deng Ziyan deng Bhupal dev tang dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi dong jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhu&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian deutsches Elektronen-Synchrotron deSY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping ring,a booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping ring are situated on the surface,while the subterranean booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical design Report(TDR)follows the Preliminary Conceptual design Report(Pre-CDR,2015)and the Conceptual design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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Epicardial isolation of pulmonary veins with ethanol in open chest dogs

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Chinese Medical Journal 2011年第11期124卷 1714-1719页

作者： YIN Xian-dong NING man SANG Cai-hua MIAO Cheng-long liANG Cui tang ri-bo long de-yong yu rong-hui liu xing-peng dong jian-zeng ma chang-sheng department of Cardiology Beijing Anzhen Hospital CapitalMedical University Beijing 100029 China

Background Radiofrequency （RF） ablation has become a widely accepted treatment for atrial fibrillation （AF）. This study aimed to identify the efficacy and safety of pulmonary vein （PV） ablation with ethanol and to explore an alternative energy source for catheter ablation of AF. Methods Twelve open-chest mongrel dogs were randomized into ethanol ablation group and control group. both the injections and electrophysiological mapping procedures were performed epicardialy. In ethanol ablation group （n=-6）, injections were performed to circumferentially ablate the root of each PV （0.2 ml each site, 3 mm apart） with 95% ethanol using an 1 ml injector. In control group （n=6）, saline was injected other than ethanol.

关键词： ethanol pulmonary vein isolation epicardial atrial fibrillation

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