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Effect of special types of bread with select herbal components on postprandial glucose levels in diabetic patients

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World Journal of Diabetes 2024年第4期15卷 664-674页

作者： Drasko m Gostiljac srdjan s Popovic Vesna Dimitrijevic-sreckovic sasa m Ilic Jelena A Jevtovic Dragan m Nikolic Ivan A soldatovic Clinic for Endocrinology Diabetes and Metabolic DiseasesUniversity Clinical Centre of SerbiaBelgrade 11000Serbia Faculty of medicine University of BelgradeBelgrade 11000Serbia Clinic for Gastroenterology and Hepatology University Clinical Centre of SerbiaBelgrade 11000Serbia Clinic for Endocrinology Diabetes and Metabolic Diseases-Laboratory for Human Pancreatic Islets CultureUniversity Clinical Centre of SerbiaBelgrade 11000Serbia

BACKGROUND Nutrition recommendations in patients with type 2 diabetes mellitus(T2Dm)are to consume rye or integral bread instead of white bread.A positive effect on glucoregulation has been achieved by enriching food with various biologically active substances of herbal origin,so we formulated an herbal mixture that can be used as a supplement for a special type of bread(sTB)to achieve better effects on postprandial glucose and insulin levels in patients with *** To compare organoleptic characteristics and effects of two types of bread on postprandial glucose and insulin levels in T2Dm *** This trial included 97 patients with T2Dm.A parallel group of 16 healthy subjects was also *** participants were given 50 g of rye bread and the same amount of a sTB with an herbal mixture on 2 consecutive *** blood glucose and insulin levels were compared at the 30^(th),60^(th),90^(th) and 120th min.A questionnaire was used for subjective estimation of the organoleptic and satiety features of the two types of *** Compared to patients who consumed rye bread,significantly lower postprandial blood glucose and insulin concentrations were found in T2Dm patients who consumed *** relevant differences were found among the healthy *** estimated organoleptic and satiety characteristics are better for sTB than for rye *** sTB have better effects than rye bread on postprandial glucoregulation in T2Dm *** estimated organoleptic and satiety characteristics are better for sTB than for rye ***,sTB can be recommended for nutrition in T2Dm patients.

关键词： special types of bread Postprandial glucoregulation Insulin Nutrition Type 2 diabetes mellitus

The influence of resistance exercise training prescription variables on skeletal muscle mass,strength,and physical function in healthy adults:An umbrella review

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Journal of sport and Health science 2024年第1期13卷 47-60页

作者： Jonathan C.mcleod Brad s.Currier Caroline V.Lowisz stuart m.Phillips Department of Kinesiology Faculty of ScienceMcMaster UniversityHamilton L8S4L8Canada

Purpose:The aim of this umbrella review was to determine the impact of resistance training(RT)and individual RT prescription variables on muscle mass,strength,and physical function in healthy ***:Following Preferred Reporting Items for systematic Reviews and meta-Analyses(PRIsmA)guidelines,we systematically searched and screened eligible systematic reviews reporting the effects of differing RT prescription variables on muscle mass(or its proxies),strength,and/or physical function in healthy adults aged>18 ***:We identified 44 systematic reviews that met our inclusion *** methodological quality of these reviews was assessed using A measurement Tool to Assess systematic Reviews;standardized effectiveness statements were *** found that RT was consistently a potent stimulus for increasing skeletal muscle mass(4/4 reviews provide some or sufficient evidence),strength(4/6 reviews provided some or sufficient evidence),and physical function(1/1 review provided some evidence).RT load(6/8 reviews provided some or sufficient evidence),weekly frequency(2/4 reviews provided some or sufficient evidence),volume(3/7 reviews provided some or sufficient evidence),and exercise order(1/1 review provided some evidence)impacted RT-induced increases in muscular *** discovered that 2/3 reviews provided some or sufficient evidence that RT volume and contraction velocity influenced skeletal muscle mass,while 4/7 reviews provided insufficient evidence in favor of RT load impacting skeletal muscle *** was insufficient evidence to conclude that time of day,periodization,inter-set rest,set configuration,set end point,contraction velocity/time under tension,or exercise order(only pertaining to hypertrophy)influenced skeletal muscle adaptations.A paucity of data limited insights into the impact of RT prescription variables on physical ***:Overall,RT increased muscle mass,strength,and physical function compared to no ***

关键词： Hypertrophy Resistance training Resistance training prescription variables strength Umbrella review

RPLP0/TBP are the most stable reference genes for human dental pulp stem cells under osteogenic differentiation

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World Journal of stem Cells 2024年第6期16卷 656-669页

作者： Daniel B Ferreira Leticia m Gasparoni Cristiane F Bronzeri Katiucia B s Paiva Laboratory of Extracellular matrix Biology and Cellular Interaction Department of AnatomyInstitute of Biomedical SciencesUniversity of São PauloSão Paulo 05508-000São PauloBrazil

BACKGROUND Validation of the reference gene(RG)stability during experimental analyses is essential for correct quantitative real-time polymerase chain reaction(RT-qPCR)data ***,in an unreliable way,several studies use genes involved in essential cellular functions[glyceraldehyde-3-phosphate dehydro-genase(GAPDH),18s rRNA,andβ-actin]without paying attention to whether they are suitable for such experimental conditions or the reason for choosing such ***,such studies use only one gene when minimum Information for Publication of Quantitative Real-Time PCR Experiments guidelines recom-mend two or more *** impacts the credibility of these studies and causes dis-tortions in the gene expression *** tissue engineering,the accuracy of gene expression drives the best experimental or therapeutical *** cultivated DPsCs under two conditions:Undifferentiated and osteogenic dif-ferentiation,both for 35 *** evaluated the gene expression of 10 candidates for RGs[ribosomal protein,large,P0(RPLP0),TATA-binding protein(TBP),GAPDH,actin beta(ACTB),tubulin(TUB),aminolevulinic acid synthase 1(ALAs1),tyro-sine 3-monooxygenase/tryptophan 5-monooxygenase activation protein,zeta(YWHAZ),eukaryotic translational elongation factor 1 alpha(EF1a),succinate dehydrogenase complex,subunit A,flavoprotein(sDHA),and beta-2-micro-globulin(B2m)]every 7 d(1,7,14,21,28,and 35 d)by *** data were analysed by the four main algorithms,ΔCt method,geNorm,NormFinder,and BestKeeper and ranked by the RefFinder *** subdivided the samples into eight *** All of the data sets from clonogenic and osteogenic samples were analysed using the RefFinder *** final ranking showed RPLP0/TBP as the two most stable RGs and TUB/B2m as the two least stable *** theΔCt method or NormFinder analysis showed TBP/RPLP0 as the two most stable ***,geNorm analysis showed RPLP0/EF1αin the first *** algorithms’two least stab

关键词： Dental pulp stem cells Reference gene Housekeeping gene Endogenous gene Osteogenic differentiation RefFinder

Effects of low molecular weight polysaccharide from sargassum thunbergii against palmitic acid-induced intracellular lipid accumulation in 3T3-L1 adipocyte and HepG2 cells

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Food science and Human Wellness 2024年第4期13卷 2244-2252页

作者： Hyo-Geun Lee D.P.Nagahawatta m.J.m.s.Kurera Kyung-mo song Yun-sang Choi You-Jin Jeon min-Cheol Kang Department of marine Life sciences Jeju National UniversityJeju 63243Republic of Korea Department of Biotechnology Faculty of Agriculture and Plantation ManagementWayamba University of Sri LankaMakanduraGonawila(NWP)60170Sri Lanka Research Group of Food Processing Korea Food Research Institute245Wanju 55365Republic of Korea

Low molecular weight polysaccharides can be isolated from sargassum thunbergii(LmPsT)and in vitro experiments were conducted to evaluate the inhibitory effects on *** natures of LmPsT were attained from *** and appraised their LmPsT on palmitic acid(PA)induced lipid accretion in Hep G2,and 3T3-L1 *** treatment lessened lipid deposition and intracellular free fatty acid and triglyceride intensities in PA-treated above mentioned *** mechanistic study publicized that LmPsT2 significantly suppressed adipogenesis and stimulated the PA-treated 3T3-L1 cells occupied in the lipolysis ***,in PA-treated Hep G2 cells,the free fatty acid oxidation was significantly increased by *** these constructive properties of LmPsT2 from ***,is a potential candidate for diminishing the intracellular lipids,and for a therapeutic agent in those conditions.

关键词： sargassum thunbergii Low molecular weight polysaccharide Lipid accumulation Obesity Liver steatosis

Natural Convection and Irreversibility of Nanofluid Due to Inclined magnetohydrodynamics(mHD)Filled in a Cavity with Y-shape Heated Fin:FEm Computational

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Computer modeling in Engineering & sciences 2024年第5期139卷 1505-1519页

作者： Afraz Hussain majeed Rashid mahmood sayed m.Eldin Imran saddique s.saleem muhammad Jawad school of Energy and Power Engineering Jiangsu UniversityZhenjiang212013China Department of mathematics Air UniversityIslamabad44000Pakistan Center of Research Faculty of EngineeringFuture University in EgyptNew Cairo11835Egypt Department of mathematics University of Management and TechnologyLahore54770Pakistan Department of mathematics University of SargodhaSargodha40100Pakistan Department of mathematics College of ScienceKing Khalid UniversityAbha61413Saudi Arabia Faculty of sciences The Superior UniversityLahore54000Pakistan

This study explains the entropy process of natural convective heating in the nanofluid-saturated cavity in a heated fin andmagnetic *** temperature is constant on the Y-shaped fin,insulating the topwall while the remaining walls remain *** walls are subject to impermeability and non-slip *** mathematical modeling of the problem is demonstrated by the continuity,momentum,and energy equations incorporating the inclined magnetic *** elucidating the flow characteristics Finite Elementmethod(FEm)is implemented using stable FE pair.A hybrid fine mesh is used for discretizing the *** and thermal plots concerning parameters are *** addition,a detailed discussion regarding generation energy by monitoring changes in magnetic,viscous,total,and thermal irreversibility is *** addition,line graphs are created for the u and v components of the velocity profile to predict the flow *** simulations assume the dimensionless representative of magnetic field Hartmann number Ha between 0 and 100 and a magnetic field inclination between 0 and 90 degrees.A constant 4% volume proportion of nanoparticles is employed throughout all scenarios.

关键词： Finite element method nanomaterials entropy mHD square cavity Y-fin

surgical management of Lumbar spinal Canal stenosis with Instrumentation at the Yaounde Central Hospital: Comparison of Unilateral versus Bilateral Pedicle screw Fixation Combined with Transforaminal Lumbar Interbody Fusion

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Open Journal of modern Neurosurgery 2024年第3期14卷 179-189页

作者： Orlane Toto Ndome Nassourou Oumarou Haman Dimitri Fogue Jean Bruno Ndoumou Ronaldo Fonju Anu indira Baboke Vincent De Paul Djientcheu Faculty of medicine and Pharmaceutical sciences University of Douala Douala Cameroon Department of Neurosurgery Douala General Hospital Douala Cameroon Faculty of medicine and Biomedical sciences University of Yaounde 1 Yaounde Cameroon Department of Neurosurgery Yaounde General and Central Hospitals Yaounde Cameroon Cameroon Academy of Young scientists Yaounde Cameroon

Introduction: The choice of adopting unilateral pedicle screw fixation or using bilateral pedicle screw fixation in lumbar spinal stenosis remains controversial. In our context, very few studies have been performed comparing the clinical effectiveness of unilateral versus bilateral fixation in the surgical management of lumbar spinal canal stenosis. Objective: Evaluate the impact on quality of life and clinical efficacy of unilateral spondylodesis compared to bilateral spondylodesis in the surgical management of lumbar spinal canal stenosis at the Yaounde Central Hospital. methods: This was a retrospective descriptive cross-sectional study for a period of 4 years, from June 2015 to June 2019. It involved all patients operated for lumbar canal stenosis and who underwent spondylodesis or spinal fusion at the neurosurgery department of the Yaounde Central Hospital. Results: A total of 68 participants were recruited during our study period. 32 (47%) of the study population were in the 50 - 60 age group, with a mean age of 56.98 years ranging from 41 to 75 years. Females, housewives and farmers were the most affected. In our study, 72% of patients had unilateral spondylodesis and 28% had bilateral fusion. Preoperatively, 71% of patients had insurmountable pain, refractory to medical treatment. At 3 months postoperatively, 73.7% of patients with bilateral setup had moderate pain compared to 69% of those with unilateral setup. At 6 months postoperatively, 79% of patients with bilateral fusion had mild pain compared to 82% of patients with unilateral setup. At 1 year postoperatively, all patients had mild pain. Preoperatively, 66.2% of patients were unable to walk and 19.1% of patients were bedridden according to the Oswestry score. At 3 months postoperatively, 10.2% of patients with unilateral setup were unable to walk compared to 10.5% of patients with bilateral fixation, while 67.3% of patients with unilateral fixation had moderate disability compared to 52.6% of patient

关键词： Lumbar spinal Canal stenosis Instrumentation surgery Quality of Life

Nanomotion of bacteria to determine metabolic profile

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Nanotechnology and Precision Engineering 2024年第1期7卷 1-9页

作者： s.N.Pleskova E.V.Lazarenko N.A.Bezrukov R.N.Kriukov A.V.Boryakov m.E.Dokukin s.I.surodin Research Laboratory of scanning Probe microscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia Department of Nanotechnology and Biotechnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia sarov Physics and Technology Institute National Research Nuclear University MEPhISarov 607186Russia

In addition to their visible motion such as swimming(e.g.,with the help ofﬂagella),bacteria can also exhibit nanomotion that is detectable only with highly sensitive instruments,and this study shows that it is possible to detect bacterial nanomotion using an AFm detection *** results show that the nanomotion characteristics depend on the bacterial strain,and that nanomotion can be used to sense the metabolic activity of bacteria because the oscillations are sensitive to the food preferences of the bacteria and the type of surrounding medium.

关键词： Nanomotion Bacteria Cantilever Oscillation Atomic force microscopy metabolism

Neglected congenital bilateral knee dislocation treated by quadricepsplasty with semitendinosus and sartorius transfer:A case report

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World Journal of Orthopedics 2024年第8期15卷 807-812页

作者： Osama m Qasim Abdulaziz A Abdulaziz Nibras K Aljabri Khalid s Albaqami Rayan m suqaty College of medicine Umm Al-Qura UniversityMecca 21955Makkah al MukarramahSaudi Arabia Department of Orthopedic King Faisal Medical Complex TaifTaif 26514TaifSaudi Arabia Department of Orthopedic Alnoor Specialist HospitalMecca 24241Makkah al MukarramahSaudi Arabia

BACKGROUND Congenital knee dislocation(CKD)is a rare condition,which accounts for 1%of congenital hip *** can present as an isolated condition or coexist with other genetic *** options include serial casting,percutaneous quadriceps recession,and V-Y quadricepsplasty(VYQ).The pathogenesis and hereditary patterns of CKD are not fully understood,with most cases being *** is usually managed immediately after ***,in this report,the patient was neglected for 2 *** sUmmARY A 2-year-old girl with bilateral CKD after birth presented to our hospital after failed serial casting;the patient had seizures and limited access to healthcare because of her family’s low socioeconomic *** birth was noted for a breech presentation accompanied by *** delivery took a long time,requiring immediate medical *** an infant,she had chronic diseases,including a small patent ductus arteriole,multicystic dysplastic kidney disease,and *** was found to have a bilateral knee dislocation of approximately-90°on hyperextension.A multidisciplinary team was involved,and medical care was *** underwent VYQ plus semitendinosus and sartorius *** four postoperative follow-ups,her knees were regaining mobility,and she could walk for 2-3 steps without *** This report highlights the importance of early intervention and recommends extensive studies of the management in similar cases.

关键词： Knee dislocation Congenital knee dislocation V-Y quadricepsplasty Neglect Neglected knee dislocation Pediatric orthopedics Case report

A review on transition metal oxides based photocatalysts for degradation of synthetic organic pollutants

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Journal of Environmental sciences 2024年第5期139卷 389-417页

作者： Athira Krishnan Anna swarnalal Divine Das midhina Krishnan Viswanathan s.saji smAshibli Department of Chemistry Amrita Vishwa VidyapeethamAmritapuriKerala690525India Interdisciplinary Research Center for Advanced materials King Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia Department of Chemistry University of KeralaKariavattom CampusThiruvananthapuramKerala695581India

This review provides insight into the current research trend in transition metal oxides(TmOs)-based photocatalysis in removing the organic colouring matters from *** easy understanding,the research progress has been presented in four generations according to the catalyst composition and mode of application,viz:single component TmOs(the firstgeneration),doped TmOs/binary TmOs/doped binary TmOs(the second-generation),inactive/active support-immobilized TmOs(the third-generation),and ternary/quaternary compositions(the fourth-generation).The first two generations represent suspended catalysts,the third generation is supported catalysts,and the fourth generation can be suspended or *** review provides an elaborated comparison between suspended and supported catalysts,their general/specific requirements,key factors controlling degradation,and the methodologies for performance *** the plausible fundamental and advanced dye degradation mechanisms involved in each generation of catalysts were *** existing challenges in TmOs-based photocatalysis and how the researchers approach the hitch to resolve it effectively are *** research trends are also presented.

关键词： Photocatalysis Dye degradation Transition metal oxides and composites supported catalysts suspended catalysts