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Alloy solidification: Assessment and improvement of an easy-to-apply model

Journal of materials Science & Technology 2022年第35期130卷 1-11页

作者： H.Liu Y.Liu S.L.Lu Y.Zhang H.Chen Y.Chen m.qian School of materials Science and Engineering Southwest Jiaotong UniversityChengdu 610031China Centre for Additive manufacturing School of EngineeringRMIT UniversityMelbourneVIC 3000Australia School of materials Science and Engineering Sichuan UniversityChengdu 610065China

It has been a central task of solidification research to predict solute microsegregation. Apart from the Lever rule and the Scheil-Gulliver equation, which concern two extreme cases, a long list of microsegregation models has been proposed. However, the use of these models often requires essential experimental input information, e.g., the secondary dendrite arm spacing(λ), cooling rate( ˙T) or actual solidification range(△T). This requirement disables these models for alloy solidification with no measured values for λ,˙T and △T. Furthermore, not all of these required experimental data are easily obtainable. It is therefore highly desirable to have an easy-to-apply predictive model that is independent of experimental input,akin to the Lever rule or Scheil-Gulliver model. Gong, Chen, and co-workers have recently proposed such a model, referred to as the Gong-Chen model, by averaging the solid fractions(f_(s)) of the Lever rule and Scheil-Gulliver model as the actual solid fraction. We provide a systematic assessment of this model versus established solidification microsegregation models and address a latent deficiency of the model, i.e.,it allows the Lever rule solid fraction fsto be greater than one(f_(s)> 1). It is shown that the Gong-Chen model can serve as a generic model for alloy solidification until fsreaches about 0.9, beyond which(f_(s)> 0.9) its applicability is dictated by both the equilibrium solute partition coefcient(k) and the solute diffusion coefcient in the solid(Ds), which has been tabulated in detail.

关键词： Solidification microsegregation Solute Back diffusion Eutectic formation

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Variation in pore distribution along sample length in sintered 7xxx aluminum alloy

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Transactions of Nonferrous metals Society of China 2016年第8期26卷 2019-2028页

作者： Xi-ni YUAN[[ S.m.AmINOSSADATI m.qian Research Institute Baoshan Iron & Steel Co. Ltd. Shanghai 201900 China State Key Laboratory of Development and Application Technology of Automotive Steels (BaoSteel) Shanghai 201900 China

An experimental and computational fluid dynamics (CFD) numerical study of the sintering of an Al?7Zn?2.5mg?1Cu alloy in flowing nitrogen was presented. Three rectangular bars with dimensions of 56 mm × 10 mm × 4.5 mm each, equally spaced 2 or 10 mm apart, were sintered in one batch at 620 °C for 40 min in a tube furnace. The pore distribution in the selected cross section of sintered samples was found to be dependent on the sample separation distance and the distance from the cross section examined to the sample end. A three-dimensional (3D) CFD model was developed to investigate the nitrogen gas behavior near each sintering surface of the three samples during isothermal sintering. The variation in porosity in the cross section of each sintered sample along sample length was found to be closely related to the nitrogen gas flow field near the sintering surfaces.

关键词： aluminum alloy sintering pore distribution nitrogen computational fluid dynamics (CFD) modeling

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Ultralight,ductile metal mechanical metamaterials with super elastic admissible strain(0.1)

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Journal of materials Science & Technology 2023年第31期162卷 227-233页

作者： H.Z.Zhong T.Song R.Das C.W.Li J.F.Gu m.qian Institute of materials modification and modelling Shanghai Jiao Tong UniversityShanghai 200240China Centre for Additive manufacturing School of EngineeringRMIT UniversityMelbourneVIC 3000Australia Sir Lawrence Wackett Aerospace Research Centre School of EngineeringRMIT UniversityMelbourneVIC 3000Australia

mechanical metamaterials are architectured cellular materials with unusual *** we report another type of metal mechanical metamaterials-their elastic admissible strain(EAS)is on the order of 0.1,compared to about 0.01 for common metallic *** conditions are required for a metal mechanical metamaterial to achieve this super EAS:(i)bending-dominated deformation;(ii)low density;(iii)an appropriate lattice topology,and(iv)an intrinsically high EAS for the lattice strut constituent *** findings of this work extend perspectives on metal mechanical metamaterials.

关键词： metamaterials Lattice Superelasticity Elastic admissible strain Ti-6Al-4V Titanium

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Variant selection in additively manufactured alpha-beta titanium alloys

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Journal of materials Science & Technology 2022年第18期113卷 14-21页

作者： S.L.Lu C.J.Todaro Y.Y.Sun T.Song m.Brandt m.qian Centre for Additive manufacturing School of Engineering RMIT University School of mechanical and Aerospace Engineering Nanyang Technological University

Alpha-beta(α-β)titanium alloys such as Ti-6Al-4V(wt.%,here-after the same)and Ti-6Al-2Sn-4Zr-2mo fabricated by fusion-based additive manufacturing(Am)typically exhibit a strong columnar prior-βgrain *** columnar prior-βgrains with their001along the build direction not only lead to solidification tex-ture but also cause subsequentα-phase textures[1].The forma-tion of theseα-phase textures is a consequence of theβ→αtransformation obeying the Burgers orientation relationship(BOR)[1-5],which results in[0001]of theα-phase being orientated at about either 45°or 0°relative to the *** affect the deformation behaviour and mechanical properties[1,6].Defined by the BOR,a singleβ-phase grain can bring forth 12α-phase vari-ants[2,7],leading to significant microstructural ***α-phase variants do not form randomly in eachβ-phase ***,their formation displays specific crystallographic features,known asα-variant selection,which is common in Ti *** an extreme case,α-variant selection can lead to the formation of a singleα-phase crystal through anα→β→αtransformation cy-cle[8,9].

关键词： alloys grain transformation

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modeling Cell Re-programming During Induced Pluripotency

Modeling Cell Re-programming During Induced Pluripotency

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第五届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会高通量时代的生物信息学与系统生物学

作者： Z.Hu m.qian m.Q.Zhang

Somatic cells can be reprogrammed to embryonic stem cell-like state by introducing few reprogramming *** by the phenomenological reprogramming model of Artyomov et al.(2010),we proposed a novel markov model with more realistic gene regulation rules and explored various properties of the model with monte Carlo ***,we demonstrated the utility of our model by testing it with the real dynamic gene expression data spanning across different intermediate stages in the iPSC reprogramming *** data can be predicted and explained by our model reasonably well;in turn,it lands further support on our general rules of gene regulation in iPSC reprogramming.

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Overview of in-situ oxygen production technologies for lunar resources

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International Journal of minerals,metallurgy and materials 2025年第2期32卷 233-255页

作者： Youpeng Xu Sheng Pang Liangwei Cong Guoyu qian Dong Wang Laishi Li Yusheng Wu Zhi Wang College of materials Science and Engineering Shenyang University of TechnologyShenyang 110870China CAS Key Laboratory of Green Process and Engineering National Engineering Research Center for Green Recycling of Strategic Metal ResourcesInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China Innovation Academy for Green manufacture Chinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China

The rich resources and unique environment of the moon make it an ideal location for human expansion and the utilization of extraterrestrial ***,crucial for supporting human life on the moon,can be extracted from lunar regolith,which is highly rich in oxygen and contains polymetallic *** oxygen and metal extraction can be achieved using existing metallurgical ***,the ample reserves of water ice on the moon offer another means for oxygen *** paper offers a detailed overview of the leading technologies for achieving oxygen production on the moon,drawing from an analysis of lunar resources and environmental *** delves into the principles,processes,advantages,and drawbacks of water-ice electrolysis,two-step oxygen production from lunar regolith,and one-step oxygen production from lunar *** two-step methods involve hydrogen reduction,carbothermal reduction,and hydrometallurgy,while the one-step methods encompass fluorination/chlorination,high-temperature decomposition,molten salt electrolysis,and molten regolith electrolysis(mOE).Following a thorough comparison of raw materials,equipment,technology,and economic viability,mOE is identified as the most promising approach for future in-situ oxygen production on the *** the corrosion characteristics of molten lunar regolith at high temperatures,along with the moon's low-gravity environment,the development of inexpensive and stable inert anodes and electrolysis devices that can easily collect oxygen is critical for promoting mOE technology on the *** review significantly contributes to our understanding of in-situ oxygen production technologies on the moon and supports upcoming lunar exploration initiatives.

关键词： lunar resources in-situ oxygen production space metallurgy molten lunar regolith electrolysis

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Increased excitatory amino acid transporter 2 levels in basolateral amygdala astrocytes mediate chronic stress–induced anxiety-like behavior

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Neural Regeneration Research 2025年第6期20卷 1721-1734页

作者： Xirong Xu Shoumin Xuan Shuai Chen Dan Liu qian Xiao Jie Tu Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases Shenzhen-Hong Kong Institute of Brain ScienceShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina CAS Key Laboratory of Brain Connectome and manipulation Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Brain Connectome and Behavior the Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina University of Chinese of Academy of Sciences BeijingChina Faculty of Life and Health Sciences Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina

The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain function and encoding behaviors associated with ***, astrocytes in the basolateral amygdala have been found to play a role in the modulation of anxiety-like behaviors triggered by chronic stress. Nevertheless, the precise molecular mechanisms by which basolateral amygdala astrocytes regulate chronic stress–induced anxiety-like behaviors remain to be fully elucidated. In this study, we found that in a mouse model of anxiety triggered by unpredictable chronic mild stress, the expression of excitatory amino acid transporter 2 was upregulated in the basolateral amygdala. Interestingly, our findings indicate that the targeted knockdown of excitatory amino acid transporter 2 specifically within the basolateral amygdala astrocytes was able to rescue the anxiety-like behavior in mice subjected to stress. Furthermore, we found that the overexpression of excitatory amino acid transporter 2 in the basolateral amygdala, whether achieved through intracranial administration of excitatory amino acid transporter 2agonists or through injection of excitatory amino acid transporter 2-overexpressing viruses with GfaABC1D promoters, evoked anxiety-like behavior in mice. Our single-nucleus RNA sequencing analysis further confirmed that chronic stress induced an upregulation of excitatory amino acid transporter 2 specifically in astrocytes in the basolateral amygdala. moreover, through in vivo calcium signal recordings, we found that the frequency of calcium activity in the basolateral amygdala of mice subjected to chronic stress was higher compared with normal *** knocking down the expression of excitatory amino acid transporter 2 in the basolateral amygdala, the frequency of calcium activity was not significantly increased, and anxiety-like behavior was ob

关键词： anxiety astrocytes basolateral amygdala behavior dihydrokainic acid excitatory amino acid transporter 2 fiber photometry glutamate LDN-212320 transporter

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Breeding high-yield superior quality hybrid super rice by rational design

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National Science Review 2016年第3期3卷 283-294页

作者： qian qian Longbiao Guo Steven m.Smith Jiayang Li State Key Laboratory for Rice Biology China National Rice Research InstituteChinese Academy of Agricultural Sciences State Key Laboratory of Plant Genomics and National Center for Plant Gene Research(Beijing) Institute of Genetics and Developmental BiologyChinese Academy of Sciences Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences School of Biological Sciences University of Tasmania

The challenge of meeting the increasing demand for worldwide rice production has driven a sustained quest for advances in rice breeding for yield. Two breakthroughs that led to quantum leaps in productivity last century were the introduction of semidwarf varieties and of hybrid rice. Subsequent gains in yield have been incremental. The next major leap in rice breeding is now upon us through the application of rational design to create defined ideotypes. The exploitation of wide-cross compatibility and intersubspecific heterosis,combined with rapid genome sequencing and the molecular identification of genes for major yield and quality traits have now unlocked the potential for rational design.

关键词： Oryza sativa L super rice hybrids molecular breeding grain yield grain quality

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Smart super rice

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Science China(Life Sciences) 2017年第12期60卷 1460-1462页

作者： qian qian state key laboratory for rice biology china national rice research instituteHangzhou 310006China

To commemorate the 50th anniversary of the published paper“male Sterility in Rice”written by Professor Longping Yuan in the journal Chinese Science Bulletin,Professor Qifa Zhang published a topical collection Fifty Glorious Years of Hybrid Rice by soliciting contributions in 2016,which he provided to the editorial department of Chinese Science Bulletin.

关键词： Smart super rice

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Neutrinos,supernovae,and the origin of the heavy elements

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Science China(Physics,mechanics & Astronomy) 2018年第4期61卷 1-6页

作者： YongZhong qian School of Physics and Astronomy University of MinnesotaMinneapolis 55455USA Tsung-Dao Lee Institute Shanghai 200240China

Stars of～8-100 m_⊙end their lives as core-collapse supernovae(SNe). In the process they emit a powerful burst of neutrinos,produce a variety of elements, and leave behind either a neutron star or a black hole. The wide mass range for SN progenitors results in diverse neutrino signals, explosion energies, and nucleosynthesis products. A major mechanism to produce nuclei heavier than iron is rapid neutron capture, or the r process. This process may be connected to SNe in several ways. A brief review is presented on current understanding of neutrino emission, explosion, and nucleosynthesis of SNe.

关键词： neutrino supernova nucleosynthesis the r process

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