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Inhibiting ShP2 reduces glycolysis, promotes microglial m1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model

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Neural Regeneration Research 2025年第3期20卷 858-872页

作者： Xintian Ding Chun Chen heng Zhao Bin Dai Lei ye Tao Song Shuai huang Jia Wang Tao You Department of Orthopedics The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Orthopedics Provincial Hospital Affiliated to Anhui Medical UniversityHefeiAnhui ProvinceChina

Reducing the secondary inflammatory response, which is partly mediated by microglia, is a key focus in the treatment of spinal cord injury. Src homology 2-containing protein tyrosine phosphatase 2(ShP2), encoded by PTPN11, is widely expressed in the human body and plays a role in inflammation through various mechanisms. Therefore, ShP2 is considered a potential target for the treatment of inflammation-related diseases. however, its role in secondary inflammation after spinal cord injury remains unclear. In this study, ShP2 was found to be abundantly expressed in microglia at the site of spinal cord injury. Inhibition of ShP2 expression using siRNA and ShP2 inhibitors attenuated the microglial inflammatory response in an in vitro lipopolysaccharide-induced model of inflammation. Notably, after treatment with ShP2 inhibitors, mice with spinal cord injury exhibited significantly improved hind limb locomotor function and reduced residual urine volume in the bladder. Subsequent in vitro experiments showed that, in microglia stimulated with lipopolysaccharide, inhibiting ShP2 expression promoted m2 polarization and inhibited m1 polarization. Finally, a co-culture experiment was conducted to assess the effect of microglia treated with ShP2 inhibitors on neuronal cells. The results demonstrated that inflammatory factors produced by microglia promoted neuronal apoptosis, while inhibiting ShP2 expression mitigated these effects. Collectively, our findings suggest that ShP2 enhances secondary inflammation and neuronal damage subsequent to spinal cord injury by modulating microglial phenotype. Therefore, inhibiting ShP2 alleviates the inflammatory response in mice with spinal cord injury and promotes functional recovery postinjury.

关键词： apoptosis glycolysis inflammatory response microglia neurons polarization spinal cord injury Src homology 2-containing protein tyrosine phosphatase 2

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The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases

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Neural Regeneration Research 2025年第6期20卷 1582-1598页

作者： Yanxi Li Jing Xue Yuejia ma Ke ye Xue Zhao Fangliang Ge Feifei Zheng Lulu Liu Xu Gao Dayong Wang Qing Xia Department of Biochemistry and molecular Biology College of Basic Medical SciencesHarbin Medical UniversityHarbinHeilongjiang ProvinceChina College of Basic medical Sciences Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Basic medical Institute Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Key Laboratory of heilongjiang Province for Genetically modified Animals Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Translational medicine Research and Cooperation Center of Northern China Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Dongzhimen hospital Beijing University of Chinese MedicineBeijingChina

N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis and neural regeneration, where it is highly concentrated and actively involved in these processes. Changes in m^(6)A modification levels and the expression levels of related enzymatic proteins can lead to neurological dysfunction and contribute to the development of neurological diseases. Furthermore, the proliferation and differentiation of neural stem cells, as well as nerve regeneration, are intimately linked to memory function and neurodegenerative diseases. This paper presents a comprehensive review of the roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, as well as its implications in memory and neurodegenerative diseases. m^(6)A has demonstrated divergent effects on the proliferation and differentiation of neural stem cells. These observed contradictions may arise from the time-specific nature of m^(6)A and its differential impact on neural stem cells across various stages of development. Similarly, the diverse effects of m^(6)A on distinct types of memory could be attributed to the involvement of specific brain regions in memory formation and recall. Inconsistencies in m^(6)A levels across different models of neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease, suggest that these disparities are linked to variations in the affected brain regions. Notably, the opposing changes in m^(6)A levels observed in Parkinson's disease models exposed to manganese compared to normal Parkinson's disease models further underscore the complexity of m^(6)A's role in neurodegenerative processes. The roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, and its implications in memory and neurodegenerative diseases, appear contradictory. These inconsistencies may be a

关键词： Alzheimer's disease cell self-renewal central nervous system memory microglia nerve regeneration neurodegenerative diseases neurogenesis RNA methylation

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Radiation belt electron wisp inside South Atlantic Anomaly due to terrestrial VLF transmitter observed by mSS-1

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Science China Earth Sciences 2025年第2期68卷 538-548页

作者： Yixin SUN Ying LIU Qiugang ZONG Yixin hAO hong ZOU Yuguang ye Institute of Space Physics and Applied Technology Peking UniversityBeijing 100871China State Key Laboratory of Lunar and Planetary Science Macao University of Science and TechnologyMacao 999078China max Planck Institute for Solar System Research Goettingen 37077Germany

The South Atlantic Anomaly represents a region within near-Earth space characterized by a significantly weaker geomagnetic field and a higher flux of energetic particles compared to other areas. It is a space weather hazards to Low-EarthOrbit satellites. There has been evidence that the Very Low Frequency(VLF) waves from the powerful ground VLF radio transmitter in Australia, known as NWC, have the capacity to scatter energetic electrons' pitch angle in the inner radiation *** scattering directs electrons into the drift loss cone, forms a “wisp”, characterized by its peak intensity outside the South Atlantic Anomaly(SAA), and a “rift” exhibiting minimal intensity within SAA. Our findings mark the initial observation of a“wisp” precipitation, an unusual occurrence with peak intensity detected inside the SAA, observed via the macao Science Satellite-1. Enabled by the medium-energy Electron Spectrometer onboard macao Science Satellite-1, we were able to comprehensively measure the full pitch angle distribution at Low-Earth-Orbit. This allowed us to attribute the “wisp” within the anomaly to a specific pitch angle range just outside the drift loss cone, a measurement unattainable by previous satellites. This“wisp” occurrence aligns with previous model predictions, despite being overlooked. moreover, we distinguished between the trapped and precipitating electron populations. Directly derived from the ratio of these populations, our analysis revealed that approximately 2%-5% of trapped electrons will be lost in this specific wisp due to the influence of the ground VLF *** results not only complement existing evidence of energetic electron pitch angle scattering facilitated by the ground VLF transmitter but also offer a quantitative estimation of its impact.

关键词： South Atlantic Anomaly Radiation belts Electrons precipitation VLF transmitter Wave-particle interaction

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mossbauer,optical and structural properties of Fe^(3+) ion in borate glass

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Journal of Rare Earths 2025年第1期43卷 162-170,I0006页

作者： Essam A.Elkelany hesham Y.Amin A.Samir m.m.EL-hady h.h.El-Bahnasawy moukhtar A.hassan Basic Science Department Faculty of EngineeringSinai UniversityAl-Arish45511Egypt School of Information and Electrical Engineering Hangzhou City UniversityHangzhou30015China State Key Laboratory of modern Optical Instrumentation College of Optical Science and EngineeringZhejiang UniversityHangzhou310027China Basic Science Department Faculty of Engineering at ShoubraBenha University11629Egypt Physics Department Faculty of ScienceAl-Azhar University11884CairoEgypt

Lanthanum-bearing iron lithium borate glass is a quaternary system for oxide glasses and was prepared via the melt-quenching *** present article correlates the structure,optical,ligand field and m?ssbauer data on iron lithium borate glass co ntaining La^(3+).The density was measured,while the molar volume was *** physical parameters are *** increasing the La_(2)O_(3) content within the glass network,infrared spectra analysis reveals structural modifications such as the increase in BO_(4) units and the decline in both BO_(3) units and NBO bonds ***,optical absorption spectra were *** absorption spectra disclose a plethora of electronic transitions that are related to Fe^(3+)in tetrahedral and octahedral sites,however,Fe^(2+)phase is not observed in optical spectra,but it has a clear signature in m?ssbauer ***,the glass absorption edges undergo a clear blue shift,reflecting an increased band gap energy(1.96-2.28 eV).The decline in NBO bonds justifies this ***,the values of crystal field splitting are increased,while the values of Racah parameters are *** trend is justified by the decline in NBO bonds and increases electron localization around Fe cations.m?ssbauer spectra confirm the existence of Fe^(3+)in tetrahedral and octahedral sites,while Fe^(2+)exists in only a tetrahedral *** increasing La_(2)O_(3) content,the isomer shift of Fe^(3+)in tetrahedral sites changes to be 0.312-0.329 mm/s,while the isomer shift of octahedral Fe^(3+)is 0.424-0.456 mm/*** findings coincide with optical *** the isomer shift of tetrahedral Fe^(2+)is 0.902-0.911 mm/*** results of structural,optical and ligand field associated with m?ssbauer spectra open more vistas toward the utility of these samples in the optics realm.

关键词： Fe3+ions Rare-earth oxide mossbauer spectra Ligand field parameters Optical properties

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ARChImEDES'PRINCIPLE OF FLOTATION AND FLOATING BODIES:CONSTRUCTION,EXTENSIONS AND RELATED PROBLEmS

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Acta mathematica Scientia 2025年第1期45卷 237-256页

作者： Chunyan LIU Elisabeth m.WERNER Deping ye 张宁 School of mathematics and Computer Science Wuhan Polytechnic UniversityWuhan430048China Department of mathematics Case Western Reserve UniversityClevelandOH44106USA Department of mathematics and Statistics Memorial University of NewfoundlandSt.John’sNewfoundlandCanadaA1C 5S7 Department of mathematics and Statistics Memorial University of NewfoundlandSt.John’sSchool of Mathematics and StatisticsHuazhong University of Science and Technology1037 Luoyu RoadWuhan430074China

In this article,we explain how the famous Archimedes’principle of flotation can be used to construct various floating *** survey some of the most important results regarding the floating bodies,including their relations with affine surface area and projection body,their extensions in different settings such as space forms and log-concave functions,and mention some associated open problems.

关键词： flfoating body affine surface area log-concave functions

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Exploring mechanism of Electroacupuncture in modulating Neuroinflammation Based on Intestinal Flora and Its metabolites

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Chinese Journal of Integrative medicine 2025年第2期31卷 183-192页

作者： ye hai-min LI Zhuo-yan ZhANG Peng KANG Zhen ZhOU De-sheng School of Integrated Chinese and Western medicine Hunan University of Chinese MedicineChangsha(410208)China Neurology Department The Second Affiliated Hospital of Hunan University of Chinese MedicineChangsha(410005)China Acupuncture and moxibustion massage Rehabilitation Department The Second Affiliated Hospital of Hunan University of Chinese MedicineChangsha(410005)China Neurology Department The First Hospital of Hunan University of Chinese MedicineChangsha(410011)China

Neuroinflammatory responses play an important role in the pathogenesis of various diseases,particularly those affecting the central nervous *** of neuroinflammation is a crucial therapeutic strategy for the management of central nervous system *** intestinal microbial-gut-brain axis serves as a key regulatory pathway that modulates neuroinflammatory *** flora metabolites such as short-chain fatty acids,indoles and their derivatives,lipopolysaccharides,trimethylamine oxide,and secondary bile acids exert direct or indirect effects on *** have shown that electroacupuncture(EA)modulates the composition of the intestinal microbiota and its metabolites,while also suppressing neuroinflammation by targeting the TLR4/NF-κB,NLRP3/caspase-1,and microglial cell m2-type transformation *** review discusses the mechanisms by which EA regulates neuroinflammation via intestinal microbiota and its metabolites,providing information and a foundation for further investigation of the precise therapeutic mechanisms of EA in neurological disorders.

关键词： electroacupuncture intestinal flora metabolites of intestinal flora neuroinflammation nervous system disease review

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Revisit the Gibbs-Thomson Equation Fitting of Poly(butylene succinate) Based on Oligomer Extended-Chain Crystals

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ChINESE JOURNAL OF POLYmER SCIENCE 2025年第2期43卷 392-398页

作者： Li, Na Tian, Yu-Pei Wu, Tian-Yu Zhou, Qiong ye, hai-mu China Univ Petr Coll New Energy & Mat Beijing 102249 Peoples R China

The equilibrium melting point (Tm0) is a crucial thermodynamic parameter for characterizing the crystallization and melting behavior of semi-crystalline polymers. however, the direct measurement of Tm0 poses a significant challenge because of the difficulty in physically fabricating fully-extended chain crystals of high-molecular-weight polymers. Therefore, various extrapolation equations for Tm0 have been proposed that utilize the thermal properties of ordinary folded-chain lamellae. Among these, the Gibbs-Thomson equation is one of the most commonly employed for modeling. Despite its widespread use, there are notable variations in the Tm0 values obtained by different research groups, even when based on similar samples. This raises questions about the validity and accuracy of using the Gibbs-Thomson equation to linearly extrapolate Tm0. In this study, we prepared a series of oligomer extended-chain crystals (ECCs) of poly(butylene succinate) (PBS) and used their properties for Gibbs-Thomson fitting. The results reveal a perfect linear relationship, with an extrapolated Tm0 value of 136.08 degrees C. The basal surface free energy of the oligomer ECCs was calculated as 0.084 J/m2, which is approximately twice that of folded-chain lamellae. This difference is attributed to the aggregation of highly mobile free tails on the crystal surface. The two structural features of oligomer ECCs-large thickness and fixed surface-better fulfill the conditions for applying the Gibbs-Thomson equation, ensuring its validity and accuracy. Therefore, we believe that the Gibbs-Thomson fit can produce reliable results when sufficient high-quality data are used.

关键词： Equilibrium melting point Extended-chain crystal Gibbs-Thomson equation Inclusion complex

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Anisotropy characterization of upper shanghai clays: Shear strength and small-strain stiffness

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Journal of Rock mechanics and Geotechnical Engineering 2025年第1期17卷 493-508页

作者： Lixin Lan Wenxuan Zhu Guanlin ye Qi Zhang Tongshuai Yang Department of Civil Engineering State Key Laboratory of Ocean EngineeringShanghai Key Laboratory for Digital Maintenance of Buildings and InfrastructureShanghai Jiao Tong UniversityShanghai200240China Department of Civil Engineering Shanghai Jiao Tong UniversityShanghai200240China The Fourth Construction Co. Ltd.of China Construction Eighth Engineering DivisionQingdao266100China

Comprehensive investigations have been conducted to study the structure and overconsolidation of upper Shanghai clays, i.e. Layers 2–6 clays, typically located at depths of 30–40 m. however, limited information is available on their anisotropy, and even less is known about the correlation between structure, overconsolidation, and anisotropy. In this study, the undrained anisotropy characteristics of shear strength and small-strain shear stiffness in upper Shanghai Layers 2–6 clays were thoroughly assessed using a series of K0-consolidated undrained triaxial compression (TC) and triaxial extension (TE) tests (K0 is the coefficient of lateral earth pressure at rest). The effective stress paths, shear strength, and small-strain shear stiffness from the undrained TC and TE tests demonstrate the anisotropic behaviors in upper Shanghai clays. Analyses of data from upper Shanghai clays and other clays worldwide indicate that the shear strength anisotropy ratio (Ks) converges at 0.8 as the overconsolidation ratio (OCR) and plasticity index (Ip) increase, while the small-strain shear stiffness anisotropy ratio (Re) converges at 1.0. The influence of OCR on Ks and Re is more pronounced than that of Ip and sensitivity (St). Nevertheless, no clear correlation between Ks and Re is observed in upper Shanghai clays.

关键词： Shanghai clays Anisotropy Shear strength Small-strain stiffness

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Study of BESIII trigger efficiencies with the 2018 J/ψ data

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Chinese Physics C 2021年第2期45卷 48-55页

作者： m.Ablikim m.N.Achasov P.Adlarson S.Ahmed m.Albrecht R.Aliberti A.Amoroso m.R.An Q.An X.h.Bai Y.Bai O.Bakina R.Baldini Ferroli I.Balossino Y.Ban K.Begzsuren N.Berger m.Bertani D.Bettoni F.Bianchi J.Bloms A.Bortone I.Boyko R.A.Briere h.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.Chelkov D.Y.Chen G.Chen h.S.Chen m.L.Chen S.J.Chen X.R.Chen Y.B.Chen Z.J Chen W.S.Cheng G.Cibinetto F.Cossio X.F.Cui h.L.Dai X.C.Dai A.Dbeyssi R.E.de Boer D.Dedovich Z.Y.Deng A.Denig I.Denysenko m.Destefanis F.De mori Y.Ding C.Dong J.Dong L.Y.Dong m.Y.Dong X.Dong S.X.Du Y.L.Fan J.Fang S.S.Fang Y.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.h.Feng m.Fritsch C.D.Fu Y.Gao Y.Gao Y.Gao Y.G.Gao I.Garzia P.T.Ge C.Geng E.m.Gersabeck A Gilman K.Goetzen L.Gong W.X.Gong W.Gradl m.Greco L.m.Gu m.h.Gu S.Gu Y.T.Gu C.Y Guan A.Q.Guo L.B.Guo R.P.Guo Y.P.Guo A.Guskov T.T.han W.Y.han X.Q.hao F.A.harris h hüsken K.L.he F.h.heinsius C.h.heinz T.held Y.K.heng C.herold m.himmelreich T.holtmann Y.R.hou Z.L.hou h.m.hu J.F.hu T.hu Y.hu G.S.huang L.Q.huang X.T.huang Y.P.huang Z.huang T.hussain W.Ikegami Andersson W.Imoehl m.Irshad S.Jaeger S.Janchiv Q.Ji Q.P.Ji X.B.Ji X.L.Ji h.B.Jiang X.S.Jiang J.B.Jiao Z.Jiao S.Jin Y.Jin T.Johansson N.Kalantar-Nayestanaki X.S.Kang R.Kappert m.Kavatsyuk B.C.Ke I.K.Keshk A.Khoukaz P.Kiese R.Kiuchi R.Kliemt L.Koch O.B.Kolcu B.Kopf m.Kuemmel m.Kuessner A.Kupsc m.G.Kurth W.Kühn J.J.Lane J.S.Lange P.Larin A.Lavania L.Lavezzi Z.h.Lei h.Leithoff m.Lellmann T.Lenz C.Li C.h.Li Cheng Li D.m.Li F.Li G.Li h.Li h.Li h.B.Li h.J.Li J.L.Li J.Q.Li J.S.Li Ke Li L.K.Li Lei Li P.R.Li S.Y.Li W.D.Li W.G.Li X.h.Li X.L.Li Z.Y.Li h.Liang h.Liang h.Liang Y.F.Liang Y.T.Liang L.Z.Liao J.Libby C.X.Lin B.J.Liu C.X.Liu D.Liu F.h.Liu Fang Liu Feng Liu h.B.Liu h.m.Liu huanhuan Liu huihui Liu J.B.Liu J.L.Liu J.Y.Liu K.Liu K.Y.Liu Ke Liu L.Liu m.h.Liu P.L.Liu Q.Liu Q.Liu S.B.Liu Shuai Liu T.Liu W.m.Liu X.Liu Y.Liu Y.B.Liu Z.A.Liu Z.Q.Liu X.C.Lou F.X.Lu h.J.Lu J.D.Lu J.G.Lu X.L.Lu Y.Lu Y.P.Lu C.L.Luo m.X.Luo b P.W.Luo T.Luo X.L.Luo S Institute of high Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COmSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China GIBudker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI helmholtzcentre for heavy Ion Research Gmbh D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China hangzhou Normal University Hangzhou 310036China helmholtz Institute mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University of Science and Technology Luoyang 471003China huangshan College Huangshan 245000China hunan Normal University Changsha 410081China hunan University Changsha 410082China Indian Institute of Technology madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA (A)INFN Laboratori Nazionali di Frascati I-00044FrascatiItaly(B)INFN Sezione di PerugiaI-06100PerugiaItaly(C)University of PerugiaI-06100PerugiaItaly (A)INFN Sezione di Ferrara I-44122FerraraItaly(B)University of FerraraI-44122FerraraItaly Institute of modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Ave54BUlaanbaatar 13330Mongolia Jilin University Changchun 130012China Johannes Gutenberg University of mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-Liebig-Universitaet Giessen IIPhysikalisches InstitutHeinrich-Buff-Ring 16D-35392GiessenGermany KVI-CART University of GroningenNL-9747 AA GroningenThe Netherlands Lanzhou University Lanzhou 730000China Liaoning Normal Unive

Using a dedicated data sample taken in 2018 on the J/ψpeak,we perform a detailed study of the trigger efficiencies of the BESIII *** efficiencies are determined from three representative physics processes,namely Bhabha scattering,dimuon production and generic hadronic events with charged *** combined efficiency of all active triggers approaches 100%in most cases,with uncertainties small enough not to affect most physics analyses.

关键词： BESIII trigger efficiency Bhabha dimuon hadronic events

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measurements of the center-of-mass energies of e^(+)e^(-)collisions at BESIII

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Chinese Physics C 2021年第10期45卷 7-15页

作者： m.Ablikim m.N.Achasov P.Adlarson S.Ahmed m.Albrecht R.Aliberti A.Amoroso m.R.An Q.An X.h.Bai Y.Bai O.Bakina R.Baldini Ferroli I.Balossino Y.Ban K.Begzsuren N.Berger m.Bertani D.Bettoni F.Bianchi J.Bloms A.Bortone I.Boyko R.A.Briere h.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.Chelkov D.Y.Chen G.Chen h.S.Chen m.L.Chen S.J.Chen X.R.Chen Y.B.Chen Z.J.Chen W.S.Cheng G.Cibinetto F.Cossio X.F.Cui h.L.Dai X.C.Dai A.Dbeyssi R.E.de Boer D.Dedovich Z.Y.Deng A.Denig I.Denysenko m.Destefanis F.De mori Y.Ding C.Dong J.Dong L.Y.Dong m.Y.Dong X.Dong S.X.Du Y.L.Fan J.Fang S.S.Fang Y.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.h.Feng m.Fritsch C.D.Fu Y.Gao Y.Gao Y.Gao Y.G.Gao I.Garzia P.T.Ge C.Geng E.m.Gersabeck A Gilman K.Goetzen L.Gong W.X.Gong W.Gradl m.Greco L.m.Gu m.h.Gu Y.T.Gu C.Y Guan A.Q.Guo L.B.Guo R.P.Guo Y.P.Guo A.Guskov T.T.han W.Y.han X.Q.hao F.A.harris K.L.he F.h.heinsius C.h.heinz T.held Y.K.heng C.herold m.himmelreich T.holtmann G.Y.hou Y.R.hou Z.L.hou h.m.hu J.F.hu T.hu Y.hu G.S.huang L.Q.huang X.T.huang Y.P.huang Z.huang T.hussain N husken W.Ikegami Andersson W.Imoehl m.Irshad S.Jaeger S.Janchiv Q.Ji Q.P.Ji X.B.Ji X.L.Ji Y.Y.Ji h.B.Jiang X.S.Jiang J.B.Jiao Z.Jiao S.Jin Y.Jin m.Q.Jing T.Johansson N.Kalantar-Nayestanaki X.S.Kang R.Kappert m.Kavatsyuk B.C.Ke I.K.Keshk A.Khoukaz P.Kiese R.Kiuchi R.Kliemt L.Koch O.B.Kolcu B.Kopf m.Kuemmel m.Kuessner A.Kupsc m.G.Kurth W.Kuhn J.J.Lane J.S.Lange P.Larin A.Lavania L.Lavezzi Z.h.Lei h.Leithoff m.Lellmann T.Lenz C.Li C.h.Li Cheng Li D.m.Li F.Li G.Li h.Li h.Li h.B.Li h.J.Li J.L.Li J.Q.Li J.S.Li Ke Li L.K.Li Lei Li P.R.Li S.Y.Li W.D.Li W.G.Li X.h.Li X.L.Li Xiaoyu Li Z.Y.Li h.Liang h.Liang h.Liang Y.F.Liang Y.T.Liang G.R.Liao L. Z. Liao J.Libby C.X.Lin B.J.Liu C.X.Liu D.Liu F.h.Liu Fang Liu Feng Liu h.B.Liu h.m.Liu huanhuan Liu huihui Liu J.B.Liu J.L.Liu J.Y.Liu K.Liu K.Y.Liu L.Liu m.h.Liu P.L.Liu Q.Liu Q.Liu S.B.Liu Shuai Liu T.Liu W.m.Liu X.Liu Y.Liu Y.B.Liu Z.A.Liu Z.Q.Liu X.C.Lou F.X.Lu h.J.Lu J.D.Lu J.G.Lu X.L.Lu Y.Lu Y.P.Lu C.L.Luo Institute of high Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COmSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China G.I.Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI helmholtzcentre for heavy Ion Research Gmbh D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China hangzhou Normal University Hangzhou 310036China helmholtz Institute mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University of Science and Technology Luoyang 471003China huangshan College Huangshan 245000China hunan Normal University Changsha 410081China hunan University Changsha 410082China Indian Institute of Technology madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly 25Institute of Modern PhysicsLanzhou 730000China Institute of modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Jilin University Changchun 130012China Johannes Gutenberg University of mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-Liebig-Universitaet Giessen II.Physikali

During the 2016-17 and 2018-19 running periods,the BESIII experiment collected 7.5 fb of e^(+)e^(-)collision data at center-of-mass energies ranging from 4.13 to 4.44 *** data samples are primarily used for the study of excited charmonium and charmoniumlike *** analyzing the di-muon process e^(+)e^(-)→(γISR=FSR)μ^(+)μ^(-),we measure the center-of-mass energies of the data samples with a precision of 0.6 *** a run-by-run study,we find that the center-of-mass energies were stable throughout most of the data-collection period.

关键词： center-of-mass energy e^(+)e^(-) annihilation BESIII

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