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Spatial analysis of Dengue through the reproduction numbers relating to socioeconomic features:Case studies on two brazilian urban centers

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Infectious Disease modelling 2024年第1期9卷 142-157页

作者： Ana T.C.Silva Rejane C.Dorn Lívia R.Tomás Leonardo b.L.Santos Lacita m.Skalinski Suani T.R.Pinho Departamento de Física Universidade Estadual de Feira de SantanaAv.Transnordestinas/n.Novo HorizonteFeira de Santana44036-900BABrazil Instituto de Física Universidade Federal da BahiaRua Barão de Jeremoabo s/nCampus Universitário de OndinaSalvador40170-115BABrazil Centro Nacional de monitoramento e Alertas de Desastres Naturais(CEmADEN) Estrada Dr.Altino Bondensan500São Josédos Campos12247-016SPBrazil Universidade Estadual de Santa Cruz Campus Soane Nazaréde AndradeRodovia Jorge AmadoKm 16SalobrinhoIlhéus45662-900BABrazil Instituto de Saúde Coletiva Universidade Federal da BahiaR.Basílio da Gamas/n-CanelaSalvador40110-140BABrazil Instituto Nacional de Ciência e Tecnologia-Sistemas Complexos Virtual InstitutionBrazil

The study of the propagation of infectious diseases in urban centers finds a close connection with their population's social characteristics and *** work performs a spatial analysis of dengue cases in urban centers based on the basic reproduction numbers,R0,and incidence by planning areas(PAs),as well as their correlations with the Human Development Index(HDI)and the number of *** analyzed dengue epidemics in 2002 at two brazilian urban centers,belo Horizonte(bH)and Rio de Janeiro(RJ),using PAs as spatial *** results reveal heterogeneous spatial scenarios for both cities,with very weak correlations between R0 and both the number of trips and the HDI;in bH,the values of R0 show a less spatial heterogeneous pattern than in *** bH,there are moderate correlations between incidence and both the number of trips and the HDI;meanwhile,they weakly correlate for ***,the absence of strong correlations between the considered measures indicates that the transmission process should be treated considering the city as a whole.

关键词： Dengue mathematical mode lbasic reproduction number Urban m.bility Urban indices

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Pelleting and particle size reduction of corn increase net energy and digestibility of fiber,protein,and fat in corn-soybean meal diets fed to group-housed pigs

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Journal of Animal Science and biotechnology 2024年第4期15卷 1751-1760页

作者： Su A Lee Diego A.Rodriguez Chad b.Paulk Hans H.Stein Department of Animal Sciences University of IllinoisUrbanaIL 61801USA Department of Grain Sciences and Industry Kansas State UniversityManhattanKS 66506USA

background Reduction of the particle size of corn increases energy digestibility and concentrations of digestible and metabolizable *** may also reduce particle size of grain,but it is not known if there are interactions between particle size reduction and *** objective of this experiment was to test the hypothesis that particle size reduction and pelleting,separately or in combination,increase N balance,apparent total tract digestibility(ATTD)of fiber and fat,and net energy(NE)in corn-soybean meal diets fed to group-housed *** Six corn-soybean meal-based diets were used in a 3×2 factorial design with 3 particle sizes of corn(i.e.,700,500,or 300μm)and 2 diet forms(i.e.,meal or pelleted).Pigs were allowed ad libitum access to feed and ***-four castrated male pigs(initial weight:29.52 kg;standard diviation:1.40)were allotted to the 6 diets using a 6×6 Latin square design with 6 calorimeter chambers(i.e.,4 pigs/chamber)and 6 *** consumption and CO_(2)and CH_(4)productions were measured during fed and fasting states and fecal and urine samples were *** Regardless of particle size of corn,the ATTD of gross energy(GE),N,and acid-hydrolyzed ether extract(AEE),and the concentration of NE were greater(Pmeal *** of diet form,the ATTD of GE,N,and AEE,and the concentration of NE were increased(linear;Pby reducing the particle size of corn,but the increase was greater in meal diets than in pelleted diets(interaction;Pboth pelleting and reduction of corn particle size increased nutrient digestibility and NE,but increases were greater in meal diets than in pelleted diets.

关键词： Corn Digestibility Feed technology Net energy Particle size Pelleting

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The role of N-glycosylation in cancer

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Acta Pharmaceutica Sinica b 2024年第3期14卷 1098-1110页

作者： Yu Lin David m.Lubman Department of Surgery University of Michigan Medical CenterAnn ArborMI 48109USA

Despite advances in understanding the development and progression of cancer in recent years,there remains a lack of comprehensive characterization of the cancer *** play an important role in medicine and are involved in various human disease conditions including ***-moieties participate in fundamental cancer processes like cell signaling,invasion,angiogenesis,and *** N-glycosylation significantly impacts cancer processes and targeted therapies in ***,understanding N-glycosylation in a tumor is essential for comprehending disease progression and discovering anti-cancer targets and biomarkers for therapy monitoring and *** review presents the fundamental process of protein N-glycosylation and summarizes glycosylation changes in tumor cells,including increased terminal sialylation,N-glycan branching,and ***,the role of N-glycosylation in tumor signaling pathways,migration,and metabolism are *** and glycopeptides as potential biomarkers for early detection of cancer based on site specificity have been ***,understanding and exploring the cancer glycoproteome,along with its role in medicine,implication in cancer and other human diseases,highlights the significance of N-glycosylation in tumor processes,necessitating further research for potential anticancer targets and biomarkers.

关键词： N-Glycosylated proteins Cancer signaling Cancer angiogenesis Cancer metabolism Cancer biomarkers

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A FLEXIbLE ObJECTIVE-CONSTRAINT APPROACH AND A NEW ALGORITHm FOR CONSTRUCTING THE PARETO FRONT OF mULTIObJECTIVE OPTImIZATION PRObLEmS

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Acta mathematica Scientia 2024年第2期44卷 702-720页

作者： N.HOSEINPOOR m.GHAZNAVI Faculty of mathematical Sciences Shahrood University of TechnologyShahroodIran

In this article, a novel scalarization technique, called the improved objective-constraint approach, is introduced to find efficient solutions of a given multiobjective programming problem. The presented scalarized problem extends the objective-constraint problem. It is demonstrated that how adding variables to the scalarized problem, can lead to find conditions for (weakly, properly) Pareto optimal solutions. Applying the obtained necessary and sufficient conditions, two algorithms for generating the Pareto front approximation of bi-objective and three-objective programming problems are designed. These algorithms are easy to implement and can achieve an even approximation of (weakly, properly) Pareto optimal solutions. These algorithms can be generalized for optimization problems with more than three criterion functions, too. The effectiveness and capability of the algorithms are demonstrated in test problems.

关键词： multiobjective optimization Pareto front scalarization objective-constraint approach proper efficient solution

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The Triple Helix of innovation as a double game involving domestic and foreign actors

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Journal of Data and Information Science 2024年第1期9卷 82-100页

作者： Eustache mêgnigbêto University of Antwerp Antwerpen 2000Belgium

Purpose:The collaboration relationships between innovation actors at a geographic level may be considered as grouping two separate layers,the domestic and the *** the level of each layer,the relationships and the actors involved constitute a Triple Helix *** paper distinguished three levels of analysis:the global grouping together all actors,the domestic grouping together domestic actors,and the foreign related to only actors from partner ***/methodology/approach:bibliographic records data from the Web of Science for South Korea and West Africa breakdown per innovation actors and distinguishing domestic and international collaboration are analyzed with game *** core,the Shapley value,and the nucleolus are computed at the three levels to measure the synergy between ***:The synergy operates more in South Korea than in West Africa;the government is more present in West Africa than in South Korea;domestic actors create more synergy in South Korea,but foreign more in West Africa;South Korea can consume all the foreign synergy,which is not the case of West *** limitations:Research data are limited to publication records;techniques and methods used may be extended to other research *** implications:West African governments should increase their investment in science,technology,and innovation to benefit more from the synergy their innovation actors contributed at the foreign ***,the results of the current study may not be sufficient to prove that greater investment will yield benefits from foreign ***/value:This paper uses game theory to assess innovation systems by computing the contribution of foreign actors to knowledge production at an area *** proposes an indicator to this end.

关键词： Triple Helix Game theory Core Shapley value Nucleolus South Korea West Africa

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Validation of adherence prediction system for lifestyle interventions in nonalcoholic fatty liver disease

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World Journal of Gastroenterology 2024年第20期30卷 2629-2632页

作者： meer m Chisthi Department of General Surgery Government Medical College PathanamthittaKonni 689691KeralaIndia

This editorial delves into the research article by Zeng et al published in the latest issue of World Journal of *** manuscript contributes significantly to addressing the global health issue of nonalcoholic fatty liver disease(NAFLD)by introducing and validating the Exercise and Diet Adherence Scale(EDAS).The article effectively conveys the importance of the study,highlighting the prevalence of NAFLD,the lack of approved drugs for its treatment,and the crucial role of lifestyle *** use of the Delphi method for scale development and the subsequent evaluation of its reliability add scientific rigor to the *** results demonstrate that the scale is correlated with key lifestyle indicators,which makes it a promising tool for assessing patient adherence to *** identification of specific score thresholds for predicting adherence to daily calorie intake and exercise adds practical value to the *** differentiation among scores indicative of good,average,and poor adherence enhances its clinical *** conclusion,the manuscript introduces EDAS,a valuable instrument that can contribute substantially to the field of NAFLD research and clinical practice.

关键词： Nonalcoholic fatty liver disease Lifestyle interventions Adherence assessment Exercise and Diet Adherence Scale Delphi method

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Wave propagation of a functionally graded plate via integral variables with a hyperbolic arcsine function

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 547-561页

作者： mokhtar Ellali mokhtar bouazza Ashraf m.Zenkour Smart structures Laboratory University of Ain TemouchentAin Temouchent 46000Algeria Department of Civil Engineering University Tahri Mohamed of BecharBechar 08000Algeria Department of mathematics Faculty of ScienceKing Abdulaziz UniversityJeddah 21589Saudi Arabia Laboratory of materials and Hydrology(LmH) University of Sidi Bel AbbesSidi Bel Abbes 22000Algeria Department of mathematics Faculty of ScienceKafrelsheikh UniversityKafrelsheikh 33516Egypt

Several studies on functionally graded materials(FGms)have been done by researchers,but few studies have dealt with the impact of the modification of the properties of materials with regard to the functional propagation of the waves in *** work aims to explore the effects of changing compositional characteristics and the volume fraction of the constituent of plate materials regarding the wave propagation response of thick plates of *** model is based on a higher-order theory and a new displacement field with four unknowns that introduce indeterminate integral variables with a hyperbolic arcsine *** FGm plate is assumed to consist of a mixture of metal and ceramic,and its properties change depending on the power functions of the thickness of the plate,such as linear,quadratic,cubic,and inverse *** utilizing Hamilton’s principle,general formulae of the wave propagation were obtained to establish wave modes and phase velocity curves of the wave propagation in a functionally graded plate,including the effects of changing compositional characteristics of materials.

关键词： FGm plate effects of material properties wave propagation indeterminate integral variables inverse sinus hyperbolic function

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Parametric investigation on the novel and cost-effective nano fly ash impregnated geopolymer system for sustainable construction

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Frontiers of Structural and Civil Engineering 2024年第2期18卷 170-183页

作者： R.mOHANA S.m.Leela bHARATHI Department of Civil Engineering Mepco Schlenk Engineering CollegeSivakasi 626123India

The hazardous environmental effects of greenhouse gas emissions and climate change demand alternative sources for cementitious materials in the construction *** development of geopolymer structures provides a way of producing 100%cement-free *** this research work,a novel and simple way of deriving nano particles from waste fly ash particles is *** effect of adding the synthesized nano fly ash particles as a filler medium in geopolymer mortars was investigated by considering strength and durability *** optimization was done by using regression analysis on the geopolymer mortar and the impact of adding nano fly ash particles was studied by varying different percentages of addition ranging from 0 to 7.5%by weight of binder *** the results,it was observed that 1%nano fly ash acted not only as a filler but also as nano-sized precursors of the polymerization process,resulting in denser geopolymer *** can explain the extraordinary gain in strength of 72.11 mPa as well as the denser core with negligible level of chloride ion penetration,making the material suitable for the development of structures susceptible to marine environment.

关键词： geopolymer nano fly ash chloride ion penetration durability polymerization fillers

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Storylines of family medicine Ⅻ:family medicine and the healthcare system

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Family medicine and Community Health 2024年第S3期12卷 109-118页

作者： William.b Ventres Leslie A Stone Jeannette E South-Paul Kendall m Cam.bell Aerial R Petty Hima Ekanadham Kurt C Stange Rebecca S Etz William L miller Robert L Ferrer marianna Kong Thomas bodenheimer Roger Strasser Sharon C m Reece Joshua Freeman John m Westfall Family and Preventive medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA meharry medical College NashvilleTennesseeUSA Family medicine University of Texas Medical Branch at Galveston School of MedicineGalvestonTexasUSA Family medicine Residency Program New York-Presbyterian Columbia University Medical CenterNew YorkNew YorkUSA Center for Family and Community medicine Columbia University Vagelos College of Physicians and SurgeonsNew YorkNew YorkUSA Center for Community Health Integration Case Western Reserve University School of MedicineClevelandOhioUSA Family medicine and Population Health Virginia Commonwealth University School of MedicineRichmondVirginiaUSA Family medicine Lehigh Valley Health NetworkAllentownPennsylvaniaUSA University of South Florida morsani College of medicine TampaFloridaUSA Family and Community medicine UT Health San Antonio Long School of MedicineSan AntonioTexasUSA Family and Community medicine University of California San Francisco School of MedicineSan FranciscoCaliforniaUSA Northern Ontario School of medicine University SudburyOntarioCanada Family medicine Baylor Scott and White HealthTempleTexasUSA Family medicine University of Kansas School of MedicineKansas CityKansasUSA DARTNet Insitute AuroraColoradoUSA

Storylines of Family medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅻ:Family medicine and the future of the healthcare system’,authors address the following themes:‘Leadership in family medicine’,‘becoming an academic family physician’,‘Advocare—our call to act’,‘The paradox of primary care and three simple rules’,‘The quadruple aim—melding the patient and the health system’,‘Fit-for-purpose medical workforce’,‘Universal healthcare—coverage for all’,‘The futures of family medicine’and‘The 100th essay.’may readers of these essays feel empowered to be part of family medicine’s exciting future.

关键词： system illustration family

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Viscoelastic potential flow instability theory of Rivlin-Ericksen electrified fluids of cylindrical interface

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Journal of Ocean Engineering and Science 2024年第4期9卷 311-316页

作者： D.m.mostafa Department of mathematics College of ScienceQassim UniversityPO Box 6644Buraidah 51452Saudi Arabia Department of mathematics Faculty of EducationAin Shams UniversityRoxyCairoEgypt

A linear electrohydrodynamic Kelvin-Helmholtz instability of the interface between two viscoelastic Rivlin-Ericksen fluids enclosed by two concentric horizontal cylinders has been studied via the viscoelastic potential flow *** dispersion equation of complex coefficients for asymmetric disturbance has been obtained by using normal mode *** stability criteria are analyzed theoretically and illustrated *** imaginary part of growth rate is plotted versus the wave *** influences of dynamic viscoelastic,uniform velocities,Reynolds number,electric field,dynamic viscosity,density fluids ratio,dielectric constant ratio and inner fluid fraction on the stability of the system are *** study finds its significance in Ocean pipelines to transfer oil or gas such as Eastern Siberia-Pacific Ocean oil pipeline.

关键词： Rivlin-Ericksen fluid Cylindrical flow Viscoelastic potential flow Electrohydrodynamics stability

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