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Search for the doubly charmed baryon ■

Science China(Physics,mechanics & Astronomy) 2020年第2期63卷 8-22页

作者： R.Aaij C.Abellán Beteta T.Ackernley B.Adeva m.Adinolfi H.Afsharnia C.A.Aidala S.Aiola Z.Ajaltouni S.Akar P.Albicocco J.Albrecht F.Alessio m.Alexander A.Alfonso Albero G.Alkhazov P.Alvarez Cartelle A.A.Alves Jr S.Amato Y.Amhis L.An L.Anderlini G.Andreassi m.Andreotti F.Archilli J.Arnau Romeu A.Artamonov m.Artuso K.Arzymatov E.Aslanides m.Atzeni B.Audurier S.Bachmann J.J.Back S.Baker V.Balagura W.Baldini A.Baranov R.J.Barlow S.Barsuk W.Barter m.Bartolini F.Baryshnikov G.Bassi V.Batozskaya B.Batsukh A.Battig V.Battista A.Bay m.Becker F.Bedeschi I.Bediaga A.Beiter L.J.Bel V.Belavin S.Belin N.Beliy V.Bellee K.Belous I.Belyaev G.Bencivenni E.Ben-Haim S.Benson S.Beranek A.Berezhnoy *** D.Berninghoff H.C.Bernstein E.Bertholet A.Bertolin C.Betancourt F.Betti m.O.Bettler Ia.Bezshyiko S.Bhasin J.Bhom m.S.Bieker S.Bifani P.Billoir A.Birnkraut A.Bizzeti m.Bjφrn m.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska V.Bocci O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar S.Borghi m.Borisyak m.Borsato J.T.Borsuk T.J.V.Bowcock C.Bozzi S.Braun A.Brea Rodriguez m.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu E.Buchanan A.Buonaura C.Burr A.Bursche J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese S.Cali R.Calladine m.Calvi m.Calvo Gomez A.Camboni P.Campana D.H.Campora Perez L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini P.Carniti K.Carvalho Akiba A.Casais Vidal G.Casse m.Cattaneo G.Cavallero R.Cenci J.Cerasoli m.G.Chapman m.Charles Ph.Charpentier G.Chatzikonstantinidis m.Chefdeville V.Chekalina C.Chen S.Chen A.Chernov S.-G.Chitic V.Chobanova m.Chrzaszcz A.Chubykin P.Ciambrone m.F.Cicala X.Cid Vidal G.Ciezarek F.Cindolo P.E.L.Clarke m.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo A.Comerma-montells A.Contu N.Cooke G.Coombs S.Coquereau G.Corti C.m.Costa Sobral B.Couturier D.C.Craik J.Crkovska A.Crocombe m.Cruz Torres R.Currie C.L.Da Silva E.Dall'Occo J.Dalseno C.D'Ambrosio A.Danilina P.d'Argent A.Davis O.De Aguiar Francisco K.De Bruyn S.De Capua m Centro Brasileiro de Pesquisas Fisicas(CBPF) Rio de JaneiroBrazil Universidade Federal do Rio de Janeiro(UFRJ) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute Of High Energy Physics(IHEP) BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance Universite Clermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix marseille Univ CNRS/IN2P3CPPMMarseilleFrance LAL Univ.Paris-SudCNRS/IN2P3Universite Paris-SaclayOrsayFrance LPNHE Sorbonne Universite Paris Diderot Sorbonne Paris Cite CNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultat Physik Technische Universitat DortmundDortmundGermany max-Planck-Institut für Kernphysik(mPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN Sezione di Genova GenovaItaly INFN Sezione di milano-Bicocca MilanoItaly INFN Sezione di milano MilanoItaly INFN Sezione di Cagliari MonserratoItaly INFN Sezione di Padova PadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma Tor Vergata RomaItaly INFN Sezione di Roma La Sapienza RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences KrakowPoland AGH-University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakowPoland Natio

A search for the doubly charmed baryon ■^+cc is performed through its decay to theΛ^+c K^-π^+ final state,using proton-proton collision data collected with the LHCb detector at centre-of-mass energies of 7,8 and 13 *** data correspond to a total integrated luminosity of 9 fb^-*** significant signal is observed in the mass range from 3.4 to 3.8 GeV/c^*** limits are set at 95%credibility level on the ratio of the ■^+cc production cross-section times the branching fraction to that ofΛ^+c and ■^++cc *** limits are determined as functions of the ■^+cc mass for different lifetime hypotheses,in the rapidity range from 2.0 to 4.5 and the transverse momentum range from 4 to 15 GeV/c.

关键词： charmed baryons limits on production of particles charmed quarks experimental tests

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Effect of precut sphincterotomy on post-endoscopic retrograde cholangiopancreatography pancreatitis:A systematic review and meta-analysis

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World Journal of Gastroenterology 2014年第14期20卷 4093-4101页

作者： Abhishek Choudhary Jessica winn Sameer Siddique murtaza Arif Zainab Arif Ghassan m Hammoud Srinivas R Puli Jamal A Ibdah matthew L Bechtold Division of Gastroenterology Department of Internal MedicineUniversity of Missouri-Columbia Division of Gastroenterology and Hepatology University of IllinoisPeoria CampusOSF Saint Francis Medical CenterPeoria

AIm: To conduct a systemic review and meta-analysis to investigate the role of early precut technique. multiple randomized controlled trails (RCTs) have reported conflicting results of the early precut sphincterotomy.

关键词： Early precut Endoscopic retrograde cholangiopancreatography cannulation Post-endoscopic retrograde cholangiopancreatography pancreatitis Randomized controlled trials meta-analysis

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Effect of high-intensity interval training in adolescents with asthma:The eXercise for Asthma with Commando Joe’s^(■)(X4ACJ)trial

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Journal of Sport and Health Science 2021年第4期10卷 488-498页

作者： Charles O.N.winn Kelly A.mackintosh William T.B.Eddolls Gareth Stratton Andrew m.Wilson melitta A.mcNarry Gwyneth A.Davies Swansea University medical School Singleton CampusSwansea UniversitySwansea SA28PPUK Applied Sports Technology Exercise and Medicine(A-STEM)Research CentreCollege of EngineeringBay CampusSwansea UniversitySwansea SA18ENUK Norwich medical School University of East AngliaNorwichEngland NR47TJUK

Background:Higher levels of cardiorespiratory fitness are associated with reduced asthma severity and increased quality of life in those with ***,the purpose of this study was to evaluate the effectiveness of a 6-month high-intensity interval training(HIIT)intervention in adolescents with and without ***:A total of 616 adolescents(334 boys;13.0±1.1 years,1.57±0.10 m,52.6±12.9 kg,mean±SD),including 155 with asthma(78 boys),were recruited as part of a randomized controlled trial from 5 schools(4 control and 1 intervention).The 221 intervention participants(116 boys;47 asthma)completed 6 months of school-based HIIT(30 min,3 times per week,10-30 s bouts at>90%age-predicted maximum heart rate with equal rest).At baseline,mid-intervention,post-intervention,and 3-month follow-up,measurements for 20-m shuttle run,body mass index(BmI),lung function,Pediatric Quality of Life Inventory,Paediatric Asthma Quality of Life Questionnaire,and Asthma Control Questionnaire were ***,69 adolescents(39 boys(of the 36 with asthma there were 21 boys))also completed an incremental ramp *** analysis,each group’s data(intervention and control)were divided into those with and without ***:Participants with asthma did not differ from their peers in any parameter of aerobic fitness,at any time-point,but were characterized by a greater *** intervention elicited a significant improvement in maximal aerobic fitness but no change in sub-maximal parameters of aerobic fitness,lung function,or quality of life irrespective of asthma *** in the intervention group maintained their BmI,whereas BmI significantly increased in the control group throughout the 6-month ***:HIIT represents an effective tool for improving aerobic fitness and maintaining BmI in adolescents,irrespective of asthma *** was well-tolerated by those with asthma,who evidenced a similar aerobic fitness to their healthy peers and responded equally

关键词： Body mass index Cardiorespiratory fitness Intermittent exercise Intervention Quality of life

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Group dynamics motivation to increase exercise intensity with a virtual partner

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Journal of Sport and Health Science 2019年第3期8卷 289-297页

作者： Stephen Samendinger Christopher R.Hill Norbert L.Kerr Brian winn Alison Ede James m.Pivarnik Lori Ploutz-Snyder Deborah L.Feltz Department of Kinesiology Michigan State University NASA Johnson Space Center Universities Space Research Association Department of Psychology Michigan State University Department of media and Information College of Communication Arts & Sciences Michigan State University

Background: The effect of the K?hler group dynamics paradigm(i.e., working together with a more capable partner where one's performance is indispensable to the team outcome) has been shown to increase motivation to exercise longer at a strength task in partnered exercise video games (exergames) using a software-generated partner(SGP). However, the effect on exercise intensity with an SGP has not been investigated. The purpose of this study was to examine the motivation to maintain or increase exercise intensity among healthy, physically active middle-aged adults using an SGP in an aerobic ***: Participants(n = 85, mean age = 44.9 years) exercised with an SGP in a 6-day cycle ergometer protocol, randomly assigned to either(a)no partner control,(b) superior SGP who was not a teammate, or(c) superior SGP as a teammate(team score was dependent on the inferior member). The protocol alternated between 30-min continuous and 4-min interval lhigh-intensity session days, during which participants could change cycle power output(watts) from target intensity to alter distance and ***: mean change in watts from a targeted intensity(75% and 90% maximum heart rate) was the primary dependent variable reflecting motivational effort. Increases in performance over baseline were demonstrated without significant differences between conditions. Self-efficacy and enjoyment were significantly related to effort in the more intense interval ***: Under these conditions, no K?hler effect was observed. Exercise performance during the higher-intensity interval format is more closely related to enloyment and self-efficacy beliefs compared to the continuous sessions.

关键词： Exercise intensity Kohler effect motivation Software-generated partner

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Combined treatment of pancreatic cancer xenograft with 90Y-ITGA6B4-mediated radioimmunotherapy and PI3K/m TOR inhibitor

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World Journal of Gastroenterology 2017年第42期23卷 7551-7562页

作者： winn Aung Atsushi B Tsuji Hitomi Sudo Aya Sugyo Yoshinori Ukai Katsushi Kouda Yoshikazu Kurosawa Takako Furukawa Tsuneo Saga Tatsuya Higashi Department of molecular Imaging and Theranostics National Institute of Radiological SciencesNational Institutes for Quantum and Radiological Science and Technology(QST-NIRS) Perseus Proteomics Inc. Innovation Center for Advanced medicine Fujita Health University Department of Radiological and medical Laboratory Sciences Nagoya University Graduate School of Medicine Department of Diagnostic Radiology Kyoto University Hospital

AIm To investigate the therapeutic effect of combined integrin α6β4-targeted radioimmunotherapy(RIT) and PI3 K/m TOR inhibitor BEZ235 in a pancreatic cancer *** Phosphorylation of Akt, m TOR, the downstream effectors eukaryotic initiation factor 4 E binding protein 1(4 EBP1) and S6 ribosomal protein(S6) were evaluated in Bx PC-3 human pancreatic cancer cells treated with Yttrium-^(90)(^(90) Y) labeled anti-integrin α6β4 antibody(ITGA6 B4) and BEZ235 by western blotting. The cytotoxic effect of BEZ235 was investigated using a colony formation assay. Therapeutic efficacy enhancement by oral BEZ235 administration was assessed using mice bearing Bx PC-3 xenograft tumors. Tumor volume measurements and immunohistochemical analyses(cell proliferation marker Ki-67, DNA damage marker p-H2 AX and p-4 EBP1 staining) of tumors were performed for evaluation of combined treatment with ^(90) Y-ITGA6 B4 plus BEZ235, or each arm *** We found that phosphorylation of Akt(p-Akt), 4 EBP1(p-4 EBP1) and S6(p-S6) was inhibited by BEZ235. Colony formation in Bx PC-3 cells was additively suppressed by the combination of ^(90) Y-ITGA6 B4 and BEZ235. Pretreatment with BEZ235 before ^(90) Y-ITGA6 B4 exposure resulted in significant reduction of cells plating efficiency(PE)(0.54 ± 0.11 vs 2.81 ± 0.14 with 185 k Bq/m L ^(90) Y-ITGA6 B4 exposure, P m L ^(90) Y-ITGA6 B4 exposure, P mbined treatment with ^(90) Y-ITGA6 B4 plus BEZ235 enhanced the inhibition of tumor growth and statistically significant differences of relative tumor volume were observed for 27 d after the treatment start date when compared with the ^(90) Y-ITGA6 B4 single injection treatment(1.03 ± 0.38 vs 1.5 ± 0.15 at Day 27, P mpared with the BEZ235 treatment alone(1.8 ± 0.7 vs 3.14 ± 1.19 at Day 41, P mors from treatment groups showed reduction in volumes, dec

关键词： Radioimmunotherapy Pancreatic cancer Anti-integrin α6β4 antibody Yttrium-90 NVP-BEZ235

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Evaluating for unrecognized deficits in perimetry associated with functional upper eyelid malposition

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Advances in Ophthalmology Practice and Research 2024年第1期4卷 39-44页

作者： Linyan Wang Davin C.Ashraf michael Deiner Oluwatobi O.Idowu Seanna R.Grob Bryan J.winn m Reza Vagefi Robert C.Kersten Department of Ophthalmology The Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiangChina Department of Ophthalmology University of CaliforniaSan FranciscoUSA Department of Ophthalmology Oregon Health and Science UniversityPortlandUSA Department of Ophthalmology Tufts Medical CenterBostonUSA Department of Ophthalmology University of UtahSalt Lake CityUtahUSA

Objective:To investigate whether functional upper eyelid malposition is associated with unrecognized deficits in automated perimetry among glaucoma patients by examining patients undergoing eyelid surgery who had not been identified as requiring eyelid taping during glaucoma field ***:In this retrospective pre-post study,an automated database search followed by manual chart review was used to identify eligible patients from January 2012 to march *** patients had reliable visual field testing within two years before and after functional upper blepharoplasty or ptosis repair and no comorbid ocular *** part of routine practice,glaucoma visual field technicians taped patients with pupil-obstructing eyelid malposition;taped examinations were excluded from *** and demographic characteristics,mean deviation,and pattern standard deviation were evaluated within a two year period before and after eyelid ***:The final analysis included 60 eyes of 38 *** in visual field parameters after eyelid surgery did not reach statistical significance in crude or adjusted *** patients with ptosis,the margin reflex distance-1 was not associated with change in mean deviation after surgery(Pearson R^(2)=0.0061;P=0.700).Five of 17 eyes excluded from analysis due to unreliable pre-operative visual fields demonstrated substantial improvement after ***:Functional upper eyelid malposition does not appear to cause spurious visual field abnormalities among glaucoma patients with reliable visual fields who were determined not to require eyelid taping at the time of their visual *** visual fields could be a sign of eyelid interference in this population.

关键词： Visual field Ptosis Dermatochalasis Glaucoma Perimetry Visually significant

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Chemical Exposure Hazardous for Fish Hyphessobrycon eques through the Incorrect Release of Oil in Amazon Region

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Journal of Fisheries Science 2020年第2期2卷 19-23页

作者： Natalino da Costa Sousa Arthur dos Santos da Silva Keber Santos Costa Junior Francisco Alex Lima Barros Geisy Correa de Oliveira Pedro Rodrigo Nery de Souza Claudmilson Rodrigues de mesquita Bruna de jesus Santos Alexander Damaceno Lima santos winnícius muniz dos Santos Sá Nayara Siqueira dos Santos márcia Valéria Silva do Couto Federal University of Pará(UFPA) Campus BragançaAlameda Leandro RibeiroBragança68600-000PABrazil Federal University of Pará(UFPA) Campus de TucuruíRua Itaipu36-Vila PermanenteTucuruí68464-000PABrazil Federal University of de Sergipe(UFS) Av.Marechal Rondons/n-Jardim Rosa ElzeSão Cristóvão49100-000SEBrasil Faculdade Pio Décimo Av.Pres.Tancredo Neves 5655-Jabotiana49095-000Aracaju–SE.Brazil

Incorrect discard of oil used by fishing ship in the brazilian north region has become a common *** the possible hazard to the aquatic organisms,still missing scientific data about their ***,this study aimed to evaluate the stress and lethality caused by lubricant oil(FSAOLU)on fish Hyphessobrycon ***,it was used six different concentration diluted in water(0,22,24,26,28,30 and 32%of oil)and three replaces during 96 *** the end or during the experiment(with dying fish),it was collected blood samples(cutting the caudal fin)to determine physiological *** FSAOLU showed mean lethal dose(LD50-96h)of 27.36%,classified as toxic causing alterations in glucose values from the 26%.The greater dilution of FSAOLU(32%)increased 115%in glucose values when compared to the ***,lubricant oil when discarded in water,it present hazard to the aquatic organisms causing stress and mortality for fish being necessary adequate management to discard of this residue.

关键词： Toxicity FSA Sensibility Stress

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颅内肿瘤:脑池角作为中脑压迫的测量指标以评估肿瘤栓塞术后临床恶化风险

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国际医学放射学杂志 2009年第4期32卷 397-397页

作者： R. Gilad G.m. Fatterpekar C.D. Gandhi H.R. winn D.m. Johnson A.B. Patel 杨静（译）张雪宁（校） Department of Neurosurgery Mount Sinai School of Medicine 1 Gustave Levy Pl New YorkNY 10029. 不详

目的确定预示颅内大的肿瘤行栓塞术后临床恶化的客观影像学特征。方法本回顾性研究符合HIPAA法案,并得到机构伦理委员会的批准,免除知情同意书。在12例颅内大的肿瘤并接受过栓塞术治疗的病人中,分析有可能预示栓塞术后神经系统病情急性... 详细信息

目的确定预示颅内大的肿瘤行栓塞术后临床恶化的客观影像学特征。方法本回顾性研究符合HIPAA法案,并得到机构伦理委员会的批准,免除知情同意书。在12例颅内大的肿瘤并接受过栓塞术治疗的病人中,分析有可能预示栓塞术后神经系统病情急性恶化的影像学特征。运用脑池角（沿大脑脚前缘划线和正中矢状面所形成的夹角）来计算巾脑压迫的程度。用血管造影来评估肿瘤栓塞术前和术后肿瘤染色的程度。对于栓塞术前、后病人的神经功能状态进行评估。

关键词：颅内肿瘤栓塞术后急性恶化脑压迫评估临床脑池机构伦理委员会

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解释多焦视觉诱发电位在屈光不正、白内障和固视偏差中的作用

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世界核心医学期刊文摘（眼科学分册） 2005年第8期1卷 45-45页

作者： winn B.J. Shin E. Odel J.G. D.C. Hood 王海燕 Department of Psychology Columbia University 405 Schermerhorn New York NY 10027 United States

Aim: To understand how refractive errors, cataracts, and fixation errors affec t multifocal visual evoked potential (mfVEP) responses. methods: monocular mfVEP responses were obtained using a pattern reversal dartboard display. For the con trol condition, visual acuity was corrected to ≥20/20 and foveal fixation was m aintained. The right eye was tested under the following conditions: simulated re fractive error, simulated cataract, steady eccentric fixation, and unsteady fixa tion. Results: No subject demonstrated significant abnormalities under control c onditions. For the simulated refractive error condition, significant centrally l ocated abnormalities were seen for all subjects. For the simulated cataract cond ition, significant abnormalities were found for three subjects. The steady eccen tric fixation condition yielded abnormalities in both eyes for all subjects whil e the unsteady fixation condition yielded significant central abnormalities in t he tested eye. With eccentric and unsteady fixation conditions, all subjects had at least one sector with a waveform polarity reversal. Conclusions: While the m fVEP is a useful tool for identifying local optic nerve damage or ruling out non -organic aetiology of visual field defects, factors such as uncorrected refract ive errors, cataract, eccentric fixation, and unsteady fixation can produce appa rent field defects on the mfVEP. With care, these problems can be correctly iden tified.

关键词：屈光不正偏心注视视野缺损多焦视诱发电位视神经损伤视力矫正位置异常非器质性靶刺激

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