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空气隙纺丝过程中的单丝破裂

国际纺织导报 2011年第12期39卷 26-27页

作者： B.Wirth m.warnecke B.Schmenk G.Seide T.Gries 湛烂瑜亚琛工业大学纺织研究所(ITA)

如果聚合物在熔点范围以下分解,就采用溶液纺丝法。与熔体纺丝法大不相同,溶剂如二甲基甲酰胺(DmF)导致成本升高。主要因素是采购、维护、处置和员工防护。空气隙纺丝法属于溶液纺丝法,能提高生产速度,部分弥补了上述缺点,空气隙提供许... 详细信息

如果聚合物在熔点范围以下分解,就采用溶液纺丝法。与熔体纺丝法大不相同,溶剂如二甲基甲酰胺(DmF)导致成本升高。主要因素是采购、维护、处置和员工防护。空气隙纺丝法属于溶液纺丝法,能提高生产速度,部分弥补了上述缺点,空气隙提供许多优点,能改变工艺气体,可能的不同液流形成多种多样的工艺。由于干法和湿法纺丝的结合,存在由两种工艺引起的单丝破裂,这种结合使整个工艺的稳定性差。目前亚琛工业大学纺织研究所(ITA)正集中研究这种工艺的纺丝试验。基于不同的机理,确定单丝破裂的典型特征是可能的。主要由文献中已知的机理描述了这类破裂,确定了有助于避免这些破裂的对策。

关键词：空气隙纺丝毛细管破裂内聚破裂伸缩破裂直径变化

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汽车工业中的高模量纤维及其技术经济展望

国际纺织导报 2011年第11期39卷 4-4,6,7页

作者： C.Wilms m.warnecke G.Seide T.Gries H.Yilmaz O.Lorz 湛烂瑜亚琛工业大学纺织学院亚琛工业大学国际经济学院

高模量纤维,特别是碳纤维和玻璃纤维,已用于各种汽车用产品中。纤维增强结构便是典型的例子,如减震器和无负荷轴承部件等。汽车行业对高模量纤维的需求极可能会继续增加。科技文献分析了这类纤维对运输行业特别是汽车业的作用,但经济观... 详细信息

高模量纤维,特别是碳纤维和玻璃纤维,已用于各种汽车用产品中。纤维增强结构便是典型的例子,如减震器和无负荷轴承部件等。汽车行业对高模量纤维的需求极可能会继续增加。科技文献分析了这类纤维对运输行业特别是汽车业的作用,但经济观点较为鲜见。通过常用的经济分析方法,说明这类材料的潜力,以填补这方面的空白。除了当前的应用外,预计高模量纤维今后将成为汽车工业通用的材料,以降低成本。

关键词：高模量纤维汽车工业应用分析潜力

modeling of aggregation kernels for fluidized beds using discrete particle model simulations

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Particuology 2014年第2期12卷 134-144页

作者： Nageswara Rao Narni mirko Peglow Gerald warnecke Jitendra Kumar Stefan Heinriche J.A.m.Kuipers Department of mathematics Rajiv Gandhi University of Knowledge TechnologiesGachibowliHyderabad 500032India Institute for Process Engineering Otto-von-Guericke-University MagdeburgUniversitatsplatz 2D-39106 MagdeburgGermany Institute for Analysis and Numerics Otto-von-Guericke-University MagdeburgUniversitatsplatz 2D-39106 MagdeburgGermany Department of mathematics ⅡT KharagpurIndia Institute of Solids Process Engineering and Particle TechnologyHamburg University of TechnologyHamburgGermany Eindhoven University of Technology-SmR P.O.Box 5135600 MB EindhovenThe Netherlands

Aggregation is one of the many important processes in chemical and process engineering. Several researchers have attempted to understand this complex process in fluidized beds using the macro-model of population balance equations （PBEs）. The aggregation kernel is an effective parameter in PBEs, and is defined as the product of the aggregation efficiency and collision frequency functions. Attempts to derive this kernel have taken different approaches, including theoretical, experimental, and empirical techniques. The present paper calculates the aggregation kernel using micro-model computer simulations, i.e., a discrete particle model. We simulate the micro-model without aggregation for various initial conditions, and observe that the collision frequency function is in good agreement with the shear kernel. We then simulate the micro-model with aggregation and calculate the aggregation efficiency rate.

关键词： Aggregation kernelsmulti-phase flowCollision frequency functionAggregation efficiency rateBed parameter

Neoadjuvant chemoradiation changes podoplanin expression in esophageal cancer patients

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World Journal of Gastroenterology 2020年第23期26卷 3236-3248页

作者： Ute warnecke-Eberz Patrick Plum Viola Schweinsberg Uta Drebber Christiane J Bruns Dolores T müller Arnulf H Holscher Elfriede Bollschweiler Department of General Visceral and Cancer SurgeryUniversity Hospital of CologneCologne 50937Germany Department of Dermatology University Hospital of CologneCologne 50937Germany Institute of Pathology University Hospital of CologneCologne 50937Germany Agaplesion markus Hospital Frankfurt 60431Germany

BACKGROUND Locally advanced adenocarcinoma of the esophagus(EAC) and squamous cell carcinoma(ESCC) result in a worse prognosis. Neoadjuvant treatment improves survival, however, only for responders. The transmembrane glycoprotein podoplanin is overexpressed in squamous cell carcinomas, mi RNA-363 is associated to its regulation in head and neck *** To predict therapy response and prognosis markers, and targets for novel therapies would individualize treatments leading to more favourable *** Expression of podoplanin protein has been visualized by immunohistochemistry in surgical specimens of 195 esophageal cancer patients who underwent transthoracic esophagectomy: 90 ESCC and 105 EAC with clinical T2-3, Nx, *** hundred and six patients received neoadjuvant chemoradiation. RNA was extracted from paraffin-embedded tissue, and mi RNA-363 quantified by realtime Taq man-real-time-PCR. D2-40 mab staining of > 5% was scored as high podoplanin expression(HPE). We related podoplanin and mi RNA-363 expression to histopathologic response after neoadjuvant treatment and clinicopathological characteristics, such as histological tumor type, survival rate or clinical tumor *** confirmed expression of membrane-bound podoplanin in 90 ESCC patients.26% showed HPE of > 5%. In addition, absence in EAC patients(only 2% with HPE) was shown. Lower podoplanin expression has been detected in resectionspecimen of 58 ESCC patients after neoadjuvant(RTx/CTx) treatment, only 11% with HPE, compared to 50% HPE of 32 non-pretreated primary surgery patients,P = 0.0001. This difference of podoplanin expression was confirmed comparing pre-treatment biopsies with matching post-treatment surgical specimens, P marker in 32 patients that underwent primary surgery without neoadjuvant treatment. Low(0-5%)podoplanin expression was associated with better prognosis compared to patients with HPE, P = 0.013. Podoplanin e

关键词： Esophageal cancer Response prediction Prognosis D2-40 Posttranscriptional regulation miRNA-363

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壳牌对未来车用能源多元化发展趋势的思考

汽车安全与节能学报 2020年第1期11卷 17-35页

作者：贾恬郑彬 warnecke W Kolbeck A Aradi A Kofod m Clark R Wilbrand K 壳牌(上海)技术有限公司上海201210 Shell Global Solutions(Germany)GmbH Hamburg 21107Germany Shell Global Solutions US Inc Houston 77082-3101USA Shell Global Solutions(UK)Ltd London SE17NAUK

面对能源短缺和环境污染的双重挑战,交通领域的转型升级不可避免。本文结合未来车用动力系统的发展趋势,对交通运输领域中应用的多种先进动力系统、清洁能源及替代燃料进行综述和评价,包括目前主要使用的传统液态化石燃料即汽、柴油及... 详细信息

面对能源短缺和环境污染的双重挑战,交通领域的转型升级不可避免。本文结合未来车用动力系统的发展趋势,对交通运输领域中应用的多种先进动力系统、清洁能源及替代燃料进行综述和评价,包括目前主要使用的传统液态化石燃料即汽、柴油及先进内燃机技术,清洁替代燃料(如生物燃料、天然气合成油(GTL)燃料、电转液(PTL)燃料、液化天然气(LNG)等),以及电气化动力系统(包括混合动力、纯电动和燃料电池)等,并着重讨论液体燃料。壳牌认为没有一种单一的解决方案可以解决复杂的能源问题,未来交通能源结构将呈现多种能源并存的特点,并分别适用于不同的场景。该文还介绍了壳牌近期基于不同政治、经济和社会发展程度提出的3种远景(壳牌“高山”、“海洋”和“天空”远景),提出壳牌对未来车用能源领域转型脱碳发展情景的思考。

关键词：清洁替代燃料内燃机技术生物燃料天然气合成油(GTL) 电转液(PTL)燃料液化天然气(LNG) 电气化动力总成远景预测

Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer

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World Journal of Gastroenterology 2009年第48期15卷 6061-6067页

作者： Hakan Alakus Stefan P mnig Ute warnecke-Eberz Gül Alakus Günther Winde Uta Drebber Klaus J Schmitz Kurt W Schmid Kathrin Riemann Winfried Siffert Elfriede Bollschweiler Arnulf H Hlscher Ralf metzger Department of General Visceral and Cancer SurgeryCenter for Integrated OncologyUniversity of Cologne Department of Gastrointestinal Surgery Klinikum Herford Institute of Pathology University of Cologne Institute of Pathology and Neuropathology University Hospital of EssenUniversity of Duisburg-Essen Institute of Pharmaco-genetics University Hospital of EssenUniversity of Duisburg-Essen

AIm： To analyze the impact of the GNAS1 T393C polymorphism on prognosis and histopathology of gastric cancer. mETHODS： Genomic DNA was extracted from paraffinembedded tissues of 122 patients with primary gastric carcinoma and from the blood of 820 healthy white individuals. Allelic discrimination was performed by quantitative real-time polymerase chain reaction. Genotyping was correlated with histopathologic parameters and with overall survival according to the Kaplan-meier approach and with multivariate analysis by multiple stepwise regression. RESULTS： Thirty-nine （32%） patients displayed a CC genotype, 57 （46.7%） a CT genotype and 26 （21.3%） a TT genotype. The frequency of the C allele （fC） in the patient group was 0.55, which was not significantly different from that of healthy blood donors. The distribution was compatible with the Hardy-Weinberg equilibrium. Analysis of clinicopathological parameters did not show any significant correlation of the T393C genotype with gender （P = 0.50）, differentiation （P = 0.29）, pT-category （P = 0.19）, pN-category （P = 0.30）, pm-category （P = 0.25）, R-category （P = 0.95）, the classifications according to WHO （P = 0.34）, Lauren （P = 0.16）, Goseki （P = 1.00） and ming （P =0.74）. Dichotomization between C＋（CC＋CT） and C-genotypes （FI）, however, revealed significantly more advanced tumor stages （P = 0.023） and lower survival rates （P = 0.043） for C allele carriers. CONCLUSION： The present study provides strong evidence to suggest that the GNAS1 T393C allele carrier status influences tumor progression and survival in gastric cancer with higher tumor stages and a worse outcome for C allele carriers.

关键词： Gastric cancer G Protein Polymorphism Prognosis Tumor stage

mind the gap:acute bilateral vocal cord palsy in CIDP after extending the IVIG treatment interval?

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Neuroimmunology and Neuroinflammation 2021年第3期8卷 211-215页

作者： Liesa Regner Bendix Labeit Paul muhle Tobias Ruck Rainer Dziewas Tobias warnecke Sonja Suntrup-Krueger Department of Neurology with Institute of Translational Neurology University Hospital MünsterMünster 48149Germany

Cranial nerve involvement is rarely seen in chronic inflammatory demyelinating polyneuropathy(CIDP).We present a patient diagnosed with CIDP who was in a stable medical condition under long-term treatment with intravenous immunoglobulin(IVIG)every five weeks for more than seven *** a 12-day delay in the patient's regular IVIG therapy,he developed acute bilateral vocal cord *** patient had to be intubated and tracheostomized because of acute respiratory *** from mechanical ventilation was complicated due to *** antibiotic treatment and restarting IVIG therapy vocal cord palsy rapidly improved allowing for subsequent *** coincidence between treatment delay and symptom development does not prove definitive causality this case report may serve as a reminder how time critical IVIG therapy can be for sufficient symptom ***,it provides evidence that IVIG therapy may be effective for the treatment of cranial nerve symptoms in CIDP.

关键词： Bilateral vocal fold palsy chronic inflammatory demyelinating polyneuropathy intravenous immunoglobulin case report

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碳纤维市场现状概述

国际纺织导报 2011年第6期39卷 4-4,6,16页

作者： m. warnecke C. Wilms G. Seide T. Gries H. Yilmaz O．Lorz 原婷婷（译）李毓陵（校）亚琛工业大学纺织技术研究所德国亚琛工业大学国际经济学院德国不详

简述了目前生产者的情况并给出参与该市场的公司的信息。文中碳纤维信息来源于8家知名生产厂商、新的竞争者和一些即将进军该领域的公司。这些公司都采用聚丙烯腈为原料,这是由于其作为生产碳纤维基材的自身优势。

关键词：碳纤维市场现状