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transport mechanism in chemically reactive hybrid nanofluid flow containing gyrotactic micro-organisms over a curved oscillatory surface

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 177-192页

作者： m.NAVEED m.ImRAN t.ASGHAR Z.ABBAS Department of mathematics Division of Science and TechnologyUniversity of Education Department of mathematics The Islamia University of Bahawalpur

this paper examines the transport analysis, including both heat transfer and mass transfer, in hybrid nanofluid flow containing gyrotactic microorganisms towards a curved oscillatory surface. the influence of magnetic fields is also inspected in terms of their physical characteristics. to depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterogeneous and homogeneous chemical reactions are also incorporated. Utilizing a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorganism field, and energy. An analytical solution to the obtained flow equations is achieved utilizing the homotopy analysis method(HAm).the effects of significant flow parameters on the pressure and microorganism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via graphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. Graphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homogeneous reaction strength parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterogeneous reaction strength *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorganism difference parameter, and the bio-convective Lewis number.

关键词： Peclet number

Does acid pickling of mg-Ca alloy enhance biomineralization?

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Journal of magnesium and Alloys 2021年第3期9卷 1028-1038页

作者： Shebeer A rahim VP muhammad Rabeeh m A Joseph t Hanas Department of mechanical Engineering National Institute of Technology CalicutKerala 673601India Nanomaterials Research Laboratory School of Materials Science and EngineeringNational Institute of Technology CalicutKerala 673601India

the mechanical and physical properties of biodegradable magnesium(mg)alloys make them suitable for temporary orthopaedic *** success of these alloys depends on their performance in the physiological *** the present work,surface modification of mg-Ca binary alloy by acid pickling for better biomineralization and controlled biodegradation is *** corrosion rates of nitric and phosphoric acid treated samples were analysed by conducting electrochemical corrosion *** vitro degradation behaviour was studied using immersion test in simulated body fluid(SBF).the sample surfaces were characterized using scanning electron microscope(SEm),energy dispersive X-ray spectroscopy(EDS),Fourier transform infrared spectroscopy(FtIR)and X-ray photoelectron spectroscopy(XPS).It is seen that acid pickling leads to significant improvement in biomineralization and develop in situ calcium phosphate(Ca P)coating on the sample *** addition,the treated samples recorded a reduced degradation rate in the SBF compared to untreated ***,acid pickling is suggested as an effective surface treatment method to tailor the biomineralization and degradation behaviour of the mg-Ca alloy in the physiological environment.

关键词： Inorganic acid pickling magnesium alloy Surface pretreatment Surface characterization Biomineralization Degradation rate

the impact of alpha-fetoprotein(AFP),child-turcotte-pugh(CtP)score and disease staging on the survival of hepatocellular carcinoma(HCC)patients:a retrospective cohort from single oncology center

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Oncology Research 2025年第1期33卷 149-160页

作者： NASSER mULLA YOUSEF KAtIB ASIm m.ALmUGHAmSI DUAA S.ALKHAYAt mOHAmED mOSAAD SAmIR t.ALFOtIH RAWAN ALAOFI Department of Internal medicine Faculty of MedicineTaibah UniversityMadinah42278Saudi Arabia Department of Radiology Faculty of MedicineTaibah UniversityMadinah42278Saudi Arabia Department of Surgery Faculty of MedicineTaibah UniversityMadinah42278Saudi Arabia Department of Endemic and Infectious Diseases Suez Canal UniversityIsmailia41522Egypt King Salman bin Abdulaziz medical City Madinah42311Saudi Arabia Prince mohammed Bin Abdulaziz Hospital Madinah41511Saudi Arabia

Background:Hepatocellular carcinoma(HCC)is the most common cause of cancer-related death in Saudi *** study aimed to investigate the patterns of HCC and the effect of tNm staging,Alfa-fetoprotein(AFP),and Child-turcotte Pugh(CtP)on patients’overall survival(OS).methods:A retrospective analysis was conducted on 43 HCC patients at a single oncology center in Saudi Arabia from 2015 to *** patients had to fulfill one of the following criteria:(a)a liver lesion reported as definitive HCC on dynamic imaging and/or(b)a biopsy-confirmed ***:the mean patient age of all HCC cases was 66.8 with a male-to-female ratio of 3.3:*** patients were stratified into two groups:viral HCC(n=22,51%)and non-viral HCC(n=21,49%).Among viral-HCC patients,55%were due to HBV and 45%due to *** was diagnosed in 79%of *** and sex did not significantly statistically differ in OS among viral and non-viral HCC patients(p-value>0.05).About 65%of patients had tumor size>5 cm during the diagnosis,with a significant statistical difference in OS(p-value=0.027).AFP was>400 ng/ml in 45%of the *** was a statistically significant difference in the OS in terms of AFP levels(p-value=0.021).A statistically significant difference was also observed between the CtP score and OS(p-value=0.02).CtP class B had the longest *** was the most common treatment provided to HCC patients followed by sorafenib *** was a significant statistical difference in OS among viral and non-viral HCC patients(p-value=0.008).Conclusions:the most common predictors for OS were the underlying cause of HCC,AFP,and tumor *** having non-viral etiology,a tumor size>5 cm,an AFP>400 ng/mL,and a CtP score class C were all negatively associated with OS.

关键词： Hepatocellular carcinoma Pattern Alpha-fetoprotein(AFP) Child-turcotte-pugh Progression free survival

Correction of failure in antenna array using matrix pencil technique

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Chinese Physics B 2017年第6期26卷 491-498页

作者： S U Khan m K A rahim Advanced RF & microwave Research Group Department of Communication Engineering Faculty of Electrical Engineering Universiti Teknologi Malaysia 81310 Skudai Johor Malaysia

In this paper a non-iterative technique is developed for the correction of faulty antenna array based on matrix pencil technique（mPt）. the failure of a sensor in antenna array can damage the radiation power pattern in terms of sidelobes level and nulls. In the developed technique, the radiation pattern of the array is sampled to form discrete power pattern information set. then this information set can be arranged in the form of Hankel matrix（Hm） and execute the singular value decomposition（SVD）. By removing nonprincipal values, we obtain an optimum lower rank estimation of Hm. this lower rank matrix corresponds to the corrected pattern. then the proposed technique is employed to recover the weight excitation and position allocations from the estimated matrix. Numerical simulations confirm the efficiency of the proposed technique, which is compared with the available techniques in terms of sidelobes level and nulls.

关键词： array correction low rank estimation matrix pencil technique singular value decomposition

Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. the generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. this adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. the role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. this organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. these mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

SBL-JP-0004:A promising dual inhibitor of JAK2 and PI3KCD against gastric cancer

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Oncology Research 2025年第1期33卷 235-243页

作者： HASSAN m.OtIFI Department of Pathology College of MedicineKing Khalid UniversityAbha62521Saudi Arabia

Background:Gastric cancer(GC)remains a global health burden and is often characterized by heterogeneous molecular profiles and resistance to conventional *** phosphoinositide 3-kinase and PI3K and Janus kinase(JAK)signal transducer and activator of transcription(JAK-StAt)pathways play pivotal roles in GC progression,making them attractive targets for therapeutic ***:this study applied a computational and molecular dynamics simulation approach to identify and characterize SBL-JP-0004 as a potential dual inhibitor of JAK2 and PI3KCD *** and SNU-5 GC cells were used for in vitro ***:SBL-JP-0004 exhibited a robust binding affinity for JAK2 and PI3KCD kinases,as evidenced by molecular docking scores and molecular dynamics *** interactions and Gibbs binding free energy estimates confirmed stable and favorable interactions with target ***-JP-0004 displayed an half-maximal inhibitory concentration(IC_(50))value of 118.9 nm against JAK2 kinase and 200.9 nm against PI3KCD ***-JP-0004 exhibited potent inhibition of cell proliferation in KAtOIII and SNU-5 cells,with half-maximal growth inhibitory concentration(GI50)values of 250.8 and 516.3 nm,respectively.A significant elevation in the early phase apoptosis(28.53%in KAtOIII cells and 26.85%in SNU-5 cells)and late phase apoptosis(17.37%in KAtOIII cells and 10.05%in SNU-5 cells)were observed with SBL-JP-0004 treatment compared to 2.1%and 2.83%in their respective ***:the results highlight SBL-JP-0004 as a promising dual inhibitor targeting JAK2 and PI3KCD kinases for treating GC and warrant further preclinical and clinical investigations to validate its utility in clinical settings.

关键词： Gastric cancer(GC) Dual inhibition JAK2 PI3KCD SBL-JP-0004 molecular docking molecular dynamics simulation

mitochondria–cGAS–StING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología molecular Severo Ochoa(CBm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

the word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

Crystallization kinetics of overlapping phases in Se70te15Sb15 using isoconversional methods

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Progress in Natural Science:materials International 2015年第2期25卷 169-177页

作者： m.A.Abdel-rahim m.m.Hafiz A.Z.mahmoud Physics Department Faculty of ScienceAssiut University Assiut 71516 Egypt

the crystallization kinetics of Se70te15Sb15 chalcogenide glass was studied by Differential Scanning Calorimetry(DSC) under non-isothermal conditions. this glass was found to have a double glass transition and double overlapped crystalline phases. the overlapped crystalline phases were successfully separated using the Gaussian fit model. the activation energy, Ec, and Avrami index, n, were determined by analyzing the data using the matausita et. al. method. A strong heating rate depending on the activation energy for the two crystalline peaks was observed. the results indicated that the transformation from amorphous to crystalline phases is a complex process involving different mechanisms of nucleation and growth. the variation of activation energy with crystalline fraction was determined by Kissenger–Akahira–Sunose(KAS) method. the obtained results of directly fitting the experimental DSC data to the calculated DSC curves indicated that the crystallization process of Se70te15Sb15 glass cannot be satisfactorily described by the Johnson–mehl–Avrami(JmA) model. Simulation results indicated that the Sestak–Berggren(SB) model is more suitable to describe the crystallization process for the studied glass. the crystalline phases for the two events were identified by using x-ray diffraction(XRD) and scanning electron microscopy(SEm).

关键词： Chalcogenides glasses Differential Scanning Calorimetry(DSC) Electron microscopy X-ray diffraction

Effect of residual structural strain caused by the addition of Co3O4 nanoparticles on the structural, hardness and magnetic properties of an Al/Co3O4 nanocomposite produced by powder metallurgy

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International Journal of minerals,metallurgy and materials 2020年第3期27卷 384-390页

作者： Seyed rahim Kiahosseini Hossein Ahmadian Department of Engineering Damghan Branch Islamic Azad University

Al composites are of interest due to their appropriate ratio of strength to *** our research,an Al/Co3O4 nanocomposite was generated using a sintering *** powders of Al with various Co3O4 nanoparticle contents(0 wt%,0.5 wt%,1.0 wt%,1.5 wt%,2.0 wt%,and2.5 wt%)were first blended using planetary milling for 30 min,and compressed in a cylindrical steel mold with a diameter of 1 cm and a height of5 cm at a pressure of 80 *** samples were evaluated with X-ray diffractometry(XRD),scanning electron microscopy(SEm),Vickers hardness,and a vibrating sample magnetometer(VSm).Although the crystallite size of the Al particles remained constant at 7–10 nm,the accumulation of nanoparticles in the Al particle interspace increased the structural tensile strain from 0.0045 to 0.0063,the hardness from HV 28 to HV 52 and the magnetic saturation from 0.044 to 0.404 emu/g with an increase in Co3O4 nanoparticle content from 0 wt%to 2.5 wt%.

关键词： Residual strain Vickers hardness vibrating sample magnetometer scanning electron microscopy