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Getting physical with medical education:Exercise based virtual anatomy review classes for medical students

World Journal of methodology 2025年第1期15卷 20-25页

作者： Nadeesha R samarasinghe Taniya s Nagpal michele L Barbeau Charys m martin Division of General surgery Faculty of MedicineUniversity of British ColumbiaVancouver V6T 1Z3BCCanada Faculty of Kinesiology Sport and RecreationUniversity of AlbertaEdmonton T6G 2R3ABCanada Anatomy and Cell Biology University of Western OntarioLondon N6A 3K7ONCanada Department of Anatomy and Cell Biology Schulich School of Medicine and DentistryThe University of Western OntarioLondon N6A 3K7ONCanada

The benefits of regular physical activity are well ***,few studies have examined the effectiveness of integrating physical activity(PA)into curricula within a post-secondary *** investigate the incorporation of PA into medical curriculum,we developed a series of optional exercise-based review sessions designed to reinforce musculoskeletal(msK)anatomy course *** synchronous sessions were co-taught by a group fitness instructor and an anatomy *** fitness instructor would lead students through both strength and yoga style exercises,while the anatomy instructor asked questions about relevant anatomical structures related to course material previously *** the sessions,participants were asked to evaluate the classes on their self-reported exam preparedness in improving msK anatomy knowledge,PA levels,and mental *** participants completed surveys;a majority agreed that the classes increased understanding of msK concepts(90.0%)and activity levels(97.7%).many(70.0%)felt that the classes helped reduce *** majority of respondents(90.0%)agreed that the classes contributed to increased feelings of social ***,medical students saw benefit in PA based interventions to supplement msK course *** with increasing activity levels and promoting health behaviours,integrating PA into medical curriculum may improve comprehension of learning material,alleviate stress and foster social connectivity among medical students.

关键词： medical education musculoskeletal Anatomy Exercise Online learning

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Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia s.Rex David J.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included Pubmed,the National science Foundation(NsF),the NEI,the Blue Ridge Institute for medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

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Unlocking hypoglycemia–associated brain microvascular dysfunction:critical insights from proteomic analysis

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Neural Regeneration Research 2025年第6期20卷 1707-1708页

作者： siva s.V.P.sakamuri Anil sakamuri Department of Chemistry Auburn University at MontgomeryMontgomeryALUSA Vascular Biology Center and Department of medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hypoglycemia-a critical complication linked to worsened brain function in diabetic subjects:Hypoglycemia is characterized by a decline in circulatory glucose levels below sta nda rd physiological *** hypoglycemia,classified as level 1 hypoglycemia,is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate *** hypoglycemia,denoted by blood glucose levels less than 54 mg/dL,poses a life-threatening risk if left *** with type 1 and type 2 diabetes undergoing insulin treatment are particularly susceptible to hypoglycemia due to impaired counterregulatory mechanisms.

关键词： impaired intake critical

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Touristic urbanization and greening of coastal dune fields:A long-term assessment of a temperate sandy barrier of Argentina

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Journal of Geographical sciences 2025年第1期35卷 206-230页

作者： GARZO Pedro Andrés DADON JoséRoberto IsLA Federico Ignacio Instituto de Investigaciones marinas y Costeras(IImyC-CONICET/UNmDP) Av.Juan B.Justo 2550Mar del Plata7600Buenos AiresArgentina Instituto de Geología de Costas y del Cuaternario Dr.Enrique J.schnack(IGCC-CIC/UNmDP) Funes 3350Mar del Plata7600Buenos AiresArgentina Facultad de Arquitectura Diseño y UrbanismoCentro de Investigaciones Gestión de Espacios Costeros(GEC-FADU/UBA)Universidad de Buenos AiresIntendente Güiraldes 2160Pabellón ⅢPiso 4Ciudad Autónoma de Buenos Aires1428Argentina Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET) Buenos AiresArgentina

Dune barrier systems represent highly sought-after coastal landscapes for tourism and urban development around the ***,a century ago,they were considered hazardous environments due to their great dynamic *** a result,stabilization practices were considered *** systematic introduction of fast-growing exotic trees helped stabilize the sand,making it easier for tourism urbanization to take place,but also leading to erosion *** paper aims to assess long-term changes in vegetation cover over a large temperate barrier in *** complex region includes urban resorts,afforestation zones,and protected areas.A GIs-based geospatial analysis was conducted using a large satellite database(>350 images),and the future evolution of the vegetation was *** results revealed two primary spatiotemporal patterns associated with a gradual expansion of vegetation cover,accompanied by a concurrent reduction in sandy *** 1986,the dune area comprised 75%more surface than vegetation,whereas in 2021,it represented 60%less than ***,the 2050 scenario suggests a potential 40%reduction of dunes in certain *** is necessary to enhance management actions aimed at maintaining dune mobility and ensuring local and regional sediment ***-term management strategies must focus on restoring native plant communities and controlling invasive species,and avoiding new dune fixation initiatives based on the introduction of exotic species.

关键词： nature reserves afforestation sediment balance dune management NDVI

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The synthesis of 2′-amino-5α-cholest-6-eno [6,7-d]-thiazole derivatives under microwave irradiation using dry-media conditions

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Chinese Chemical Letters 2008年第9期19卷 1027-1030页

作者： Azharullah Khan mahboob alam m.mushfiq Department of Chemistry Aligarh Muslim UniversityAligarh 202002India Department of Chemistry Aligarh Muslim University

A convenient, rapid and efficient method for the synthesis of substituted steroidal [6,7-d] thiazoles using microwave-induced organic reaction enhancement chemistry has been developed. The additional features of this methodology include a much faster reaction, easy workup, high yield, high purity of the products and an environment friendly approach.

关键词： Dry media Neutral alumina Phenylthiourea Iodine and saturated steroidal ketones

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search for microglia-specific peptides:advances in the discovery toolbox

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Neural Regeneration Research 2025年第2期20卷 471-472页

作者： Ivan sarabia Kyle m.Koss Department of surgery University of ArizonaTucsonAZUSA

Uncontrolled and chronic inflammatory states in the central nervous system(CNs)are the hallmark of neurodegenerative pathology and every injury or stroke-related *** key mediators of these neuroinflammatory states are glial cells known as microglia,the resident immune cell at the core of the inflammatory event,and astroglia,which encapsulate inflammatory insults in proteoglycan-rich scar *** gliotic scar blocks significant portions of healthy axonal networking,preventing *** most neuroinflammation is exclusively based on the responses of said microglia,their phenotypes are suggested to follow those of macrophages;m1 and m2 are opposites of pro-and ***,microglial phenotypes have been identified to be on an inflammatory spectrum encompassing developmental,homeostatic,and reparative behaviors as opposed to their ability to affect devastating cell death cascades and scar tissue formation.

关键词： inflammation pathology death

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Paleomapping:Creating testable visual hypotheses of ancient worlds

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Journal of Palaeogeography 2025年第01期14卷 91-104页

作者： Holger Petermann Annaka m.Clement Patrick m.sullivan Hannah m.Bonner James W.Hagadorn Department of Earth and space sciences Denver Museum of Nature & Science Colorado school of mines Department of Geology and Geologic Engineering Division of Water Quality Utah Department of Environmental Quality

The story of the Earth's changing landscapes is often told through paleogeographic maps. These images are some of the most accessible and widely used illustrations in the Earth sciences. However, no formal procedure for the creation of photorealistic paleomaps(i.e., paleosatellite images) exists. Using an example from the Late Jurassic of the Rocky mountain region, we present a method for making paleoenvironmental and paleosatellite maps that is scalable, reproducible, testable, and incorporates peer review. The process includes a literature review followed by data-visualization, paleoenvironmental interpretation, peer-review,iterative revisions, and the creation of a false contour map and color gradient used to render a paleosatellite image. Paleosatellite images are photorealistic versions of paleoenvironmental maps that incorporate global climatic and tectonic information as well as principles of actualism; they can be made through comparison to analogous modern landscapes. An important component of this process is that the data maps that ground this paleomapping process allow evaluation of where paleoenvironmental interpretations are wellsupported by outcrop and subsurface data, and where such visualization is highly interpretive-often because of lack of available rocks or studies in a given area. As such, our paleoenvironmental maps and paleosatellite images are testable pictorial hypotheses. By outlining a procedure that produces referenced,data-rich, and visually realistic maps, we hope to demystify the paleoenvironmental map-making process and improve accessibility of paleomaps for the broader geoscience community. Where resources and complementary data are available, such maps also have potential for georeferencing and integration with larger continent-scale paleogeographic maps.

关键词： Ancient landscapes Cartography Paleogeography Paleoenvironments Jurassic

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Intraperitoneal Instillation of Dexmedetomidine vs Dexamethasone as Adjuvant to Bupivacaine for Postoperative Pain in Laparoscopic Cholecystectomy, a Randomized Clinical Trial

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Open Journal of Anesthesiology 2025年第1期15卷 1-12页

作者： Ayman mohamady Eldemrdash Zaher Z. Zaher Tarek s. Hemaida Taha T. Dardeer Hani m. Raslan shawky m. Abdelgalil mohmed R. saad mohammed s. Aly Anesthesiology Surgical Intensive Care and Pain Medicine and General Surgery Departments Faculty of Medicine Aswan University Aswan Egypt

Background: Intraperitoneal instillation (IPI) of local anesthesia was reported to reduce postoperative pain after laparoscopic surgeries. We aim to evaluate the effectiveness of IPI of bupivacaine + dexmedetomidine versus bupivacaine + dexamethasone on postoperative pain in patients undergoing laparoscopic cholecystectomy (LC). methods: This randomized clinical trial was carried out on one hundred patients who underwent LC under general anesthesia. Patients were randomly divided into: Group (Dexa): IPI of bupivacaine with dexamethasone and Group (Dexmed): IPI of bupivacaine with dexmedetomidine. Results: The first time to request analgesia was significantly delayed in the dexmed group (P value Conclusions: Intraperitoneal Bupivacaine + Dexmedetomidine provided longer pain-free postoperative duration lower pain score over time, and lesser analgesic consumption.

关键词： Bupivacaine Dexmedetomidine Dexamethasone Laparoscopic Cholecystectomy

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semantic segmentation of Lumbar Vertebrae Using meijering U-Net(mU-Net)on spine magnetic Resonance Images

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Computer modeling in Engineering & sciences 2025年第1期142卷 733-757页

作者： Lakshmi s V V shiloah Elizabeth Darmanayagam sunil Retmin Raj Cyril Department of Computer science and Engineering College of Engineering GuindyAnna UniversityChennai600025India Department of Information Technology Madras Institute of TechnologyAnna UniversityChrompetChennai600044India

Lower back pain is one of the most common medical problems in the world and it is experienced by a huge percentage of people *** to its ability to produce a detailed view of the soft tissues,including the spinal cord,nerves,intervertebral discs,and vertebrae,magnetic Resonance Imaging is thought to be the most effective method for imaging the *** semantic segmentation of vertebrae plays a major role in the diagnostic process of lumbar *** is difficult to semantically partition the vertebrae in magnetic Resonance Images from the surrounding variety of tissues,including muscles,ligaments,and intervertebral discs.U-Net is a powerful deep-learning architecture to handle the challenges of medical image analysis tasks and achieves high segmentation *** work proposes a modified U-Net architecture namely mU-Net,consisting of the meijering convolutional layer that incorporates the meijering filter to perform the semantic segmentation of lumbar vertebrae L1 to L5 and sacral vertebra ***-colour mask images were generated and used as ground truth for training the *** work has been carried out on 1312 images expanded from T1-weighted mid-sagittal mRI images of 515 patients in the Lumbar spine mRI Dataset publicly available from mendeley *** proposed mU-Net model for the semantic segmentation of the lumbar vertebrae gives better performance with 98.79%of pixel accuracy(PA),98.66%of dice similarity coefficient(DsC),97.36%of Jaccard coefficient,and 92.55%mean Intersection over Union(mean IoU)metrics using the mentioned dataset.

关键词： Computer aided diagnosis(CAD) magnetic resonance imaging(mRI) semantic segmentation lumbar vertebrae deep learning U-Net model

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Dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 123-138页

作者： Chentong GAO Huiyu sUN Jianping GU W.m.HUANG College of Aerospace Engineering Nanjing University of Aeronautics and Astronautics school of mechanical and Aerospace Engineering Nanyang Technological University Jiangsu Key Laboratory of Advanced structural materials and Application Technology School of Materials Science and EngineeringNanjing Institute of Technology

Currently, there are a limited number of dynamic models available for braided composite plates with large overall motions, despite the incorporation of three-dimensional(3D) braided composites into rotating blade components. In this paper, a dynamic model of 3D 4-directional braided composite thin plates considering braiding directions is established. Based on Kirchhoff's plate assumptions, the displacement variables of the plate are expressed. By incorporating the braiding directions into the constitutive equation of the braided composites, the dynamic model of the plate considering braiding directions is obtained. The effects of the speeds, braiding directions, and braided angles on the responses of the plate with fixed-axis rotation and translational motion, respectively, are investigated. This paper presents a dynamic theory for calculating the deformation of 3D braided composite structures undergoing both translational and rotational motions. It also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications.

关键词： braiding direction composite thin plate dynamic model large overall motion O313.7 three-dimensional (3D) braided composite

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