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Critical Review on Balanites aegyptiaca Delile:Phytoconstituents,Pharmacological Properties and Nanointerventions

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Chinese Journal of Integrative medicine 2024年第7期30卷 653-663页

作者： Surendra Kumar Gautam Rakesh Kumar Paul Devesh m.Sawant Amita Sarwal Kaisar raza Department of Pharmacy School of Chemical Sciences and PharmacyCentral University of RajasthanBandarsindriAjmerRajasthan305817India University Institute of Pharmaceutical Sciences Panjab UniversityChandigarh160014India

Balanites aegyptiaca Delile(BA)is an enduring xerophytic woody and spinous flowering tree and is commonly known as desert date or Ingudi(Hingot).It belongs to the family Zygophyllaceae,which is specific to be drought areas of Nigeria,Africa,South Asia and India(Rajasthan).In Ayurveda,this traditional medicinal plant is reported for the management of jaundice,syphilis,yellow fever,metabolic disorders,liver,and spleen *** main aim of the review is to compile its medicinal uses and further advancements to showcase the promises inherited in various parts of the plant for the benefit of *** per the literature survey,various researchers have focused on the detailed investigation of BA including the phytopharmacological evidence,chemical constituents,nano-formulations,commercialized products,and clinical *** remarkable scaffolds and isolated compounds like diosgenin,yamogenin,balanitin1/2,balanitin 3,bal4/5,bal6/7,rutin-3-glycosides,3,7-diglycosides,(3,12,14,16)–(12-hydroxycholest-5-ene-3,16-diyl-bis)-D-glucopyranoside and balanitoside have been ***,this traditional plant has been scientifically proven by in vitro and in *** on the complete review of this plant,most of the compounds have been isolated from the fruit and kernel ***,based on the literature,a histogram was developed for pharmacological activity in which antidiabetic study was found to be more compared to other pharmacological *** a spinous desert dates,this plant needs to be explored more to bring out newer phytochemicals in the management of various diseases.

关键词： Delile desert date phytochemicals nano-phytopharmaceutical pharmacological activities traditional medicine

Stability analysis and soliton solutions of the(1+1)-dimensional nonlinear chiral Schrodinger equation in nuclear physics

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Communications in Theoretical Physics 2024年第9期76卷 1-15页

作者： Fazal Badshah Kalim U Tariq Ahmet Bekir S m.raza Kazmi Emad Az-Zo'bi School of Electrical and Information Engineering Hubei University of Automotive TechnologyShiyan 442002China Department of mathematics Mirpur University of Science and TechnologyMirpur-10250(AJK)Pakistan Neighbourhood of Akcaglan Imarli StreetNumber:28/426030EskisehirTurkey Department of mathematics and Statistics Faculty of ScienceMutah UniversityAlKarak 61710Jordan

The nonlinear Schrodinger equation equation is one of the most important physical models used in optical fiber theory to explain the transmission of an optical *** field of chiral soliton propagation in nuclear physics is very interesting because of its numerous applications in communications and ultra-fast signal routing ***(1+1)-dimensional chiral dynamical structure that describes the soliton behaviour in data transmission is dealt with in this work using a variety of in-depth analytical *** work has applications in particle physics,ionised science,nuclear physics,optics,and other applied mathematical *** are able to develop a variety of solutions to demonstrate the behaviour of solitary wave structures,periodic soliton solutions,chiral soliton solutions,and bell-shaped soliton solutions with the use of applied ***,in order to verify the scientific calculations,the stability analysis for the observed solutions of the governing model is taken into *** addition,the3-dimensional,contour,and 2-dimensional visuals are supplied for a better understanding of the behaviour of the *** employed strategies are dependable,uncomplicated,and effective;yet have not been utilised with the governing model in the literature that is now *** resulting outcomes have impressive applications across a large number of study areas and computational physics phenomena representing real-world *** methods applied in this model are not utilized on the given models in previous literature so we can say that these describe the novelty of the work.

关键词： solitons the nonlinear Schrodinger equation stability analysis chiral solitons exact solutions

Enhancing ChatGPT’s Querying Capability with Voice-Based Interaction and CNN-Based Impair Vision Detection model

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Computers, materials & Continua 2024年第3期78卷 3129-3150页

作者： Awais Ahmad Sohail Jabbar Sheeraz Akram Anand Paul Umar raza Nuha mohammed Alshuqayran College of Computer and Information Sciences Imam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Saudia Arabia 2 School of Computer Science and EngineeringKyungpook National UniversityDaegu41566South Korea 3 Department of EngineeringManchester Metropolitan UniversityManchesterM156BHUK

This paper presents an innovative approach to enhance the querying capability of ChatGPT,a conversational artificial intelligence model,by incorporating voice-based interaction and a convolutional neural network(CNN)-based impaired vision detection *** proposed system aims to improve user experience and accessibility by allowing users to interact with ChatGPT using voice ***,a CNN-based model is employed to detect impairments in user vision,enabling the system to adapt its responses and provide appropriate *** research tackles head-on the challenges of user experience and inclusivity in artificial intelligence(AI).It underscores our commitment to overcoming these obstacles,making ChatGPT more accessible and valuable for a broader *** integration of voice-based interaction and impaired vision detection represents a novel approach to conversational ***,this innovation transcends novelty;it carries the potential to profoundly impact the lives of users,particularly those with visual *** modular approach to system design ensures adaptability and scalability,critical for the practical implementation of these ***,the solution places the user at its *** responses for those with visual impairments demonstrates AI’s potential to not only understand but also accommodate individual needs and preferences.

关键词： Accessibility in conversational AI CNN-based impair vision detection ChatGPT voice-based interaction recommender system

Recurrent acute pancreatitis as an initial presentation of primary hyperparathyroidism:A case report

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World Journal of Clinical Cases 2024年第29期12卷 6302-6306页

作者： masood m Karim Hira raza Om Parkash Department of medicine The Aga Khan University HospitalKarachi 74800SindhPakistan Department of Surgery Aga Khan University HospitalKarachi 74800SindhPakistan

BACKGROUND With 4.9 to 35 instances per 100000 cases,hyperparathyroidism is one of the rarest causes of acute *** major cause of primary hyperparathyroidism is a parathyroid adenoma,which can manifest clinically in various *** SUmmARY We discuss the unusual case of a 13-year-old boy with recurrent pancreatitis as the initial presentation of primary *** cause of his recurrent pancreatitis remained unknown,and the patient had multiple admissions with acute pancreatitis over 3 *** diagnosis was delayed due to the initial normal levels of parathyroid hormone,which were later reported elevated in a subsequent episode where ultrasound neck and thyroid scintigraphy revealed a parathyroid adenoma as the underlying *** the diagnosis was made,he underwent surgical resection of the *** This case study stresses the importance of considering uncommon causes for recurrent pancreatitis.

关键词： Recurrent pancreatitis Primary hyperparathyroidism Normal serum parathyroid hormone Parathyroid adenoma Case report

Trehalose:A sugar molecule involved in temperature stress management in plants

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The Crop Journal 2024年第1期12卷 1-16页

作者： Ali raza Savita Bhardwaj md Atikur Rahman Pedro García-Caparrós madiha Habib Faisal Saeed Sidra Charagh Christine H.Foyer Kadambot H.m.Siddique Rajeev K.Varshney College of Agriculture Fujian Agriculture and Forestry University(FAFU)Fuzhou 350002FujianChina Department of Botany School of Bioengineering and BiosciencesLovely Professional UniversityPhagwara 144411India Department of Botany MCM DAV CollegeKangraHimachal Pradesh 176001India Grassland and Forage Division National Institute of Animal ScienceRural Development AdministrationCheonan 31000Republic of Korea Agronomy Department of Superior School Engineering University of AlmeríaAlmeríaSpain National Institute for Genomics and Advanced Biotechnology National Agricultural Research CentrePark Rd.Islamabad 45500Pakistan Agriculture Health and Environment DepartmentNatural Resources InstituteFaculty of Engineering&ScienceUniversity of GreenwichKent ME44TBUK State Key Laboratory of Rice Biology China National Rice Research InstituteChinese Academy of Agricultural SciencesHangzhouZhejiangChina School of Biosciences College of Life and Environmental SciencesUniversity of BirminghamEdgbaston B152TTUK The UWA Institute of Agriculture The University of Western AustraliaCrawleyPerth 6009Australia WA State Agricultural Biotechnology Centre Centre for Crop and Food InnovationFood Futures InstituteMurdoch UniversityMurdochWA 6150Australia

Trehalose(Tre)is a non-reducing disaccharide found in many species,including bacteria,fungi,invertebrates,yeast,and even plants,where it acts as an osmoprotectant,energy source,or protein/membrane *** relatively small amounts in plants,Tre concentrations increase following exposure to abiotic ***-6-phosphate,a precursor of Tre,has regulatory functions in sugar metabolism,crop production,and stress *** the various abiotic stresses,temperature extremes(heat or cold stress)are anticipated to impact crop production worldwide due to ongoing climate *** small amounts of Tre can mitigate negative physiological,metabolic,and molecular responses triggered by temperature *** also interacts with other sugars,osmoprotectants,amino acids,and phytohormones to regulate metabolic reprogramming that underpins temperature stress *** plants expressing Tre-synthesis genes accumulate Tre and show improved stress ***-wide studies of Tre-encoding genes suggest roles in plant growth,development,and stress *** review discusses the functions of Tre in mitigating temperature stress—highlighting genetic engineering approaches to modify Tre metabolism,crosstalk,and interactions with other molecules—and in-silico approaches for identifying novel Tre-encoding genes in diverse plant *** consider how this knowledge can be used to develop temperature-resilient crops essential for sustainable agriculture.

关键词： Abiotic stress Gene expression Genetic engineering Osmolyte Trehalose-6-phosphate

Petrogenetic study of mesoproterozoic volcanic rocks of North Delhi fold belt, NW Indian shield: implications for mantle conditions during Proterozoic

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Chinese Journal Of Geochemistry 2015年第1期34卷 93-114页

作者： m.S.Azam m.Shamim Khan m.raza IGNOU Regional Center Department of Geology AMU

mesoproterozoic North Delhi fold belt of NW Indian shield comprises three volcano-sedimentary basins viz. Bayana, Alwar and Khetri aligned parallel to each other from east to west. Each basin contains excellent exposures of mafic volcanic rocks. major, trace and rare earth element abundances of volcanic rocks of the three basins are significantly diverse. Bayana and Alwar volcanics are tholeiites bearing close similarity with low Ticontinental flood basalts. However, Bayana volcanics are characteristically enriched in incompatible trace elements and REEs while Alwar volcanics display least enriched incompatible trace element abundances and flat REE patterns. The Khetri volcanics exhibit a transitional composition between tholeiite and calc-alkaline basalts. REE based source modeling suggests that Bayana suite was formed from the melts derived from 1 % to 10 %(avg.4 %) of the partial melting of a spinel lherzolite source giving a residual mineralogy of 56 % Olv, 25 % Opx and19 % Cpx. Whereas Alwar suite evolved through 12 %–20 %(avg. 15 %) partial melting of the same source with a residual mineralogy 61 % Olv, 25 % Opx and 14 % *** volcanics are exposed at two localities Kolihan and madhan–Kudhan. The Kolihan volcanics were derived from 1 % to 6 %(avg. 4 %) partial melting with residualmineralogy 56 % Olv, 25 % Opx and 19 % Cpx whereas the magma of madhan Kudhan volcanic suite was generated by 15%–30 % partial melting of the same source leaving behind 64 % Olv, 25 % Opx and 11 % Cpx as residual mineralogy. This source modeling proves that melts of Bayana and Alwar tholeiites were generated by partial melting of a common source within the spinel stability field under the influence of mantle plume. During the course of ascent, Bayana melts were crustally contaminated but Alwar melts remained unaffected. There was two tier magma production in Khetri region, one from the partial melting of the mantle wedge overlying the subducted oceanic plate which formed Kolihan

关键词：基性火山岩中元古代西印度地幔柱褶皱带岩石成因西北地盾

Adult neurogenesis:a real hope or a delusion?

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Neural Regeneration Research 2024年第1期19卷 6-15页

作者： Ghulam Hussain Rabia Akram Haseeb Anwar Faiqa Sajid Tehreem Iman Hyung Soo Han Chand raza Jose-Luis Gonzalez De Aguilar Neurochemicalbiology and Genetics Laboratory(NGL) Department of PhysiologyFaculty of Life SciencesGovernment College UniversityFaisalabadPunjabPakistan Department of Physiology School of MedicineClinical Omics InstituteKyungpook National UniversityDaeguKorea Department of Zoology Faculty of Chemistry and Life SciencesGovernment College UniversityLahorePakistan INSERm U1118Mécanismes Centraux et Péripheriques de la NeurodégénérescenceStrasbourgFranceUniversitéde StrasbourgStrasbourgFrance

Adult neurogenesis,the process of creating new neurons,involves the coordinated division,migration,and differentiation of neural stem *** process is restricted to neurogenic niches located in two distinct areas of the brain:the subgranular zone of the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricle,where new neurons are generated and then migrate to the olfactory *** has been thought to occur only during the embryonic and early postnatal stages and to decline with age due to a continuous depletion of neural stem ***,recent years have seen tremendous progress in our understanding of adult brain neurogenesis,bridging the knowledge gap between embryonic and adult ***,we discuss the current status of adult brain neurogenesis in light of what we know about neural stem *** this notion,we talk about the importance of intra cellular signaling molecules in mobilizing endogenous neural stem cell prolife *** on the current understanding,we can declare that these molecules play a role in targeting neurogenesis in the mature ***,to achieve this goal,we need to avoid the undesired proliferation of neural stem cells by controlling the necessary checkpoints,which can lead to tumorigenesis and prove to be a curse instead of a blessing or hope.

关键词： adult neurogenesis aging brain-derived neurotrophic factor dentate gyrus hippocampus neural stem cells neurotrophic factors Notch oxidative stress stem cells subgranular zone

Dust Static Cylindrically Symmetric Solutions in f(R) Gravity

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Communications in Theoretical Physics 2014年第9期61卷 348-352页

作者： m. Farasat Shamir Zahid raza Department of Sciences and Humanities National University of Computer and Emerging SciencesLahore Campus Pakistan

This paper is devoted to investigate non-vacuum solutions of cylindrically symmetric spacetime in the context of metric f(R) gravity. We take dust matter to find energy density of the universe. In particular, we find two exact solutions, which correspond to two f(R) models in each case. The first solution provides constant curvature while the second solution corresponds to non-constant curvature. The functions of the Ricci scalar and energy densities are evaluated in each case.

关键词： f(R) gravity cylindrically symmetric spacetime

mathematical modelling of Rotavirus Disease Through Efficient methods

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Computers, materials & Continua 2022年第9期72卷 4727-4740页

作者： Ali raza Department of mathematics Govt.Maulana Zafar Ali Khan Graduate College WazirabadPunjab Higher Education Department(PHED)Lahore54000Pakistan

The design of evolutionary approaches has a vital role in the recent development of scientific *** tackle highly nonlinear complex problems,nonlinear ordinary differential equations,partial differential equations,stochastic differential equations,and many more may called computational *** rotavirus causes may include severe diarrhea,vomiting,and fever leading to rapid *** the report of the World Health Organization(WHO),approximately 600,000 children die worldwide each year,80 percent of whom live in developing *** million children are hospitalized each *** Asia,up to 45 percent of the children hospitalized for diarrhea may be infected with *** rotavirus model is categorized into five-compartment like susceptible(S),breastfeeding(m),vaccinated(V),infected(I),and recovered children(R).Positivity,boundedness,equilibria,reproduction number,and stability results are part of the qualitative analysis of the *** that,the design of the evolutionary approaches on the model predicts the efficiency,visualization,long-term behavior of the disease,and best results of the rotavirus *** the end,evolutionary computations are an appropriate tool for double-checking the qualitative examination of the model.

关键词： Rotavirus disease epidemic model methods comparison analysis