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加速选择性动脉自旋标记mR血管成像对烟雾病远端动脉和侧支循环的显示

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国际医学放射学杂志 2018年第2期 229-230页

作者： O.Togao A.Hiwatashi m.obara K.Yamashita K.Kikuchi R.Kamei 邹繁婕 Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University

摘要目的以DSA为参考标准,评估并比较加速选择性动脉自旋标记(Acc ASL)mR血管成像和时间飞跃法(TOF)mR血管成像对烟雾病病人大脑动脉及侧支循环的显示情

关键词：血管成像 TOF ASL 自旋标记侧支循环烟雾病 mR

超选择性伪连续式动脉自旋标记的血管选择性4D-mR血管成像有可能作为一种有用工具用于脑AVm血流动力学的评估

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国际医学放射学杂志 2021年第1期44卷 120-120页

作者： O.Togao m.obara m.Helle K.Yamashita K.Kikuchi D.momosaka 黄黎香

摘要目的评价基于超选择性伪连续式动脉自旋标记(ASL)结合锁孔和视图共享4D-mR血管成像(4D-S-PACK)对脑动静脉畸形(AVm)血管选择性显示的价值,并探讨该技

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基于深度卷积神经网络及有与无血管抑制影像自动检测脑转移瘤

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国际医学放射学杂志 2022年第4期 488-488页

作者： Y.Kikuchi O.Togao K.Kikuchi D.momosaka m.obara m.V.Cauteren 王聪惠

摘要目的建立基于卷积神经网络（CNN）和体积各向同性黑白血同时交错采集（VISIBLE）的自动模型用于检测脑转移瘤，并与阅片者测试比较评估其诊断效能。方法该回顾

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自持放电XeCl激光器的综合研究

中国激光 1983年第Z1期 568-568页

作者： K.midorikawa H.Hokazono Y.Itoh J.Sasaki m.obara T.Fujioka 日本庆应大学电工系日本庆应大学电工系日本庆应大学电工系日本庆应大学电工系日本庆应大学电工系日本庆应大学电工系

虽然在所有的气体激光器中稀有气体卤化物激光器已获得十分迅速的发展,但一些问题尚待解决。为了设计自持放电XeCl激光器,在实验上和理论上研究了预电离对激光输出的影响及脉冲长度的定标。利用紫外和X射线预电离装置来进行这种研究,激... 详细信息

虽然在所有的气体激光器中稀有气体卤化物激光器已获得十分迅速的发展,但一些问题尚待解决。为了设计自持放电XeCl激光器,在实验上和理论上研究了预电离对激光输出的影响及脉冲长度的定标。利用紫外和X射线预电离装置来进行这种研究,激光装置由通过通道开关的水电介质双平行平面传输线驱动。放电体积为3cm(高)×3cm(宽)×50cm(长),约0.45升。为了研究预电离对XeCl激光器输出的影响,对于不含HCl的He、Ne和Xe的混合物,测量了由冷阴极X射线源产生的预电离电子的数密度。在激光器混合气体中,实际的电子密

关键词：激光器自持放电长度激光输出光激射器电子器件 XeCl 预电离

带血管抑制和不带血管抑制并行采集的三维mR成像序列在诊断脑转移瘤中的价值

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国际医学放射学杂志 2015年第3期 296-296页

作者： K.Kikuchi A.Hiwatashi O.Togao K.Yamashita m.Yoneyama m.obara 李心海 Department of Clinical Radiology Graduate School of Medical Sciences Kyushu University3-1-1 Maidashi Higashi-kuFukuoka 812-8582 Japan

目的各向同性亮/黑血间隔并行采集容积扫描(VISIBLE)技术是近年来开发的能同步获取血管抑制(黑)及无抑制(亮)影像的三维mR序列,本文旨在评估VISIBLE检

关键词：并行采集脑转移瘤黑血成像 mR 血管抑制

Hochschild cohomology ring modulo nilpotence of a one point extension of a quiver algebra defined by two cycles and a quantum-like relation

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Frontiers of mathematics in China 2016年第4期11卷 1003-1015页

作者： Daiki obara Department of mathematics Tokyo University of Science Shinjuku-ku Tokyo Japan

We consider a one point extension algebra B of a quiver algebra Aq over a field k defined by two cycles and a quantum-like relation depending on a nonzero element q in k. We determine the Hochschild cohomology ring of B modulo nilpotence and show that if q is a root of unity, then B is a counterexample to Snashall-Solberg＇s conjecture.

关键词： Hochschild cohomology, quantum-like relation one point extension

Nonlinear forced vibration in a subcritical regime of a porous functionally graded pipe conveying fluid with a retaining clip

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 101-122页

作者： m.GHOLAmI m.EFTEKHARI Department of mechanical Engineering Shahid Bahonar University of Kerman

This study examines the nonlinear behaviors of a clamped-clamped porous pipe made of a functionally graded material(FGm) that conveys fluids and is equipped with a retaining clip, focusing on primary resonance and subcritical dynamics. The nonlinear governing equations for the FGm pipe are derived by the extended Hamilton's principle, and subsequently discretized through the application of the Galerkin *** direct method of multi-scales is then used to solve the derived equations. A thorough analysis of various parameters, including the clip stiffness, the power-law index, the porosity, and the clip location, is conducted to gain a comprehensive understanding of the system's nonlinear dynamics. Through the analysis of the first natural frequency, the study highlights the influence of the flow velocity and the clip stiffness, while the comparisons with metallic pipes emphasize the role of FGm composition. The examination of the forced response curves reveals saddle-node bifurcations and their dependence on parameters such as the detuning parameter and the power-law index, offering valuable insights into the system's nonlinear resonant behavior. Furthermore, the frequency-response curves illustrate the hardening nonlinearities influenced by factors such as the porosity and the clip stiffness, revealing nuanced effects on the system response and resonance characteristics. This comprehensive analysis enhances the understanding of nonlinear behaviors in FGm porous pipes with a retaining clip, providing key insights for practical engineering applications in system design and optimization.

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The contribution of astrocytes to obesity-associated metabolic disturbances

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The Journal of Biomedical Research 2022年第5期36卷 299-311页

作者： marta obara-michlewska Department of Neurotoxicology Mossakowski Medical Research InstitutePolish Academy of SciencesWarsaw 02-106Poland

Obesity is a worldwide health,economic and social concern,despite efforts made to counteract the spreading wave of eating and nourishment-associated *** review aims to show how the glial cells,astrocytes,contribute to the central regulation of appetite and energy *** hypothalamus is the brain center responsible for nutrients and nutritional hormone sensing,signal processing,and execution of metabolic and behavioral responses,directed at sustaining energy *** astrocytes are endowed with receptors,transporters and enzymatic machinery responsible for glucose,lactate,fatty acids,ketone bodies,as well as leptin or ghrelin transport and metabolism,and that render them supporters and partners for neurons in governing the brain and body energy intake and ***,the role of astrocytes associated with brain energy metabolism reaches far beyond simple fuel contingent-they contribute to cognitive *** cognitive decline which often accompanies high fat-and/or high-calorie diets and correlates with neuroinflammation and astrogliosis,is a major *** last two decades of research enabled us to acknowledge the astroglia in obesity-associated dysfunctions and to investigate astrocytes as contributors to the pathology,as well as targets for therapy.

关键词： astrocytes astrocytosis hypothalamic inflammation obesity brain energy metabolism

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Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

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