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World Journal of Gastrointestinal Oncology 2017年第10期9卷 402-406页

作者： marcello maida Salvatore Camilleri michele manganaro Serena Garufi Giuseppe Scarpulla Section of Gastroenterology S.Elia-M.Raimondi Hospital93100 CaltanissettaItaly

Colorectal cancer(CRC) is the third most common cancer in males and second in females, and globally the fourth cause for cancer death worldwide. Oncological screening of CRC has a major role in the management of the disease and it is mostly performed by colonoscopy. Anyway, effectiveness of endoscopic screening for CRC strictly depends on adequate detection and removal of potentially precancerous lesions, and accuracy of colonoscopy in detection of adenomas is still suboptimal. For this reason, several technological advances have been implemented in order to improve the diagnostic sensitivity of colonoscopy in adenoma detection. Among these:(1) Visual technologies such as chromoendoscopy and narrow band imaging;(2) optical innovation as high definition endoscopy, full-spectrum endoscopy or Third Eye Retroscope; and(3) mechanical advances as Cap assisted colonoscopy, Endocuff, Endoring and G-Eye endoscope. All these technologies advances have been tested over time by clinical studies with mixed results. Which of them is more likely to be successful in the next future?

关键词： Colorectal cancer screening Colonoscopy Adenoma detection rate Diagnostic advances

Community-Based Cardiovascular Screening: Detection of Disease in Individuals with No Self-Reported Risk Factors

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Open Journal of Preventive medicine 2015年第2期5卷 78-83页

作者： Steven m. Weisman Nathalie I. Garbani Andrew J. manganaro Innovative Science Solutions Morristown USA Life Line Screening (LLS) Independence USA

Introduction: Community-based cardiovascular screening presents an opportunity to detect the presence of cardiovascular disease in individuals who report having no traditional risk factors, and also to identify the presence of those risk factors in those who are unaware of their health status. Identification of both disease and risk factors (e.g. high cholesterol, high blood pressure, diabetes, etc.) creates an opportunity for treatment and management to reduce and prevent cardiovascular events from occurring. methods: Over 230,000 screening records for individuals who had undergone carotid artery stenosis (CAD), abdominal aortic aneurysm (AAA), or peripheral artery disease (PAD) screening were reviewed. Participants were stratified based on self-reported risk factors as having no risk factors, one risk factor, or two or more risk factors. Self-reported risk factors were also compared with results of screening for blood pressure, blood glucose, and lipid level status. Results: Abnormal findings of CAS, AAA, and PAD were all uncovered in individuals who self-reported as having no traditional risk factors. These abnormal findings included those defined as severe. The review of self-reported risk factors for accuracy demonstrated varying levels of inaccuracies in both under and over-reporting of risk factors. Conclusions: Community-based cardiovascular screening may result in the identification of cardiovascular disease in individuals with no established risk factors. While the underreporting of risk factors has also be demonstrated, it is clear that further research is warranted to better understand the presence of disease in the absence of risk factors.

关键词： Cardiovascular Screening Risk Factors Carotid Artery Stenosis Abdominal Aortic Aneursym Peripal Artery Disease

Community-Based Screening and the Detection of Critical Carotid Artery Stenosis and Abdominal Aortic Aneurysm

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Open Journal of Preventive medicine 2015年第2期5卷 38-46页

作者： Steven m. Weisman Nathalie I. Garbani Andrew J. manganaro Innovative Science Solutions Morristown USA Life Line Screening (LLS) Independence USA

Background: Community-based cardiovascular screening has the opportunity to detect critical cardiovascular disease and positively affect public health outcomes. Disease deemed to be critical or severe at detection requires appropriate medical follow-up. This article examined the self-reported outcomes of individuals who had undergone community-based cardiovascular screening and had critical findings for abdominal aortic aneurysm (AAA) or carotid artery stenosis (CAS). methods: Over 390,000 screening records for AAA and over 490,000 screening records for CAS were reviewed to identify individuals with critical screening findings. A critical AAA is defined as an aneurysm ≥ 5cm and critical CAS is defined as a hemodynamically significant stenosis with recorded peak systolic velocities of ≥300 cm/s, in this population. Identified individuals were then contacted via phone and surveyed about the medical care they received after their screening. Results: Review of the screening records found a prevalence of critical AAA findings of 0.037% (146 participants) and critical CAS findings of 0.12% (579 participants). 61% of participants with critical findings were reached for follow-up from both groups. Over 96% of participants with critical AAA and over 92% of participants with critical CAS had some forms of medical follow-up. Conclusions: Community-based cardiovascular screening has the ability to detect critical levels of disease. Findings of critical disease in the reviewed population are similar to the findings from previously published studies. Importantly, medical treatment received by those who seek follow-up appears to be consistent with recommended treatment guidelines. Identification and management of critical disease represent meaningful public and individual health benefits and the possibility of cost-savings.

关键词： Cardiovascular Screening Carotid Artery Stenosis Abdominal Aortic Aneursym

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交错ADC揭秘

今日电子 2015年第11期 48-52页

作者： Gabriele manganaro Dave Robertson ADI公司

时间交错技术可使用多个相同的模数转换器（ADC）,并以比每一个单独数据转换器工作采样速率更高的速率来处理常规采样数据序列。简单说来,时间交错（IL）由时间多路复用m个相同的ADC并联阵列组成,如图1所示。

关键词：交错技术 ADC 采样速率模数转换器数据转换器数据序列多路复用时间

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Latest results from GRAAL collaboration

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Chinese Physics C 2009年第12期33卷 1249-1253页

作者： V. Vegna V. Bellini J.P. Bouquet L. Casano A. D'Angelo J.P. Didelez R. Di Salvo A. Fantini D. Franco G. Gervino F. Ghio G. Giardina B. Girolami A. Giusa m. Guidal E. Hourany A.S. Ignatov R. Kunnel A. Lapik A. Lleres P. Levi Sandri F. mammoliti G. mandaglio m. manganaro m. moricciani A.N. mushkarenkov V.G. Nedorezov C. Randieri D. Rebreyend N.V. Rudnev G. Russo C. Schaerf m.L. Sperduto m.C. Sutera A.Turinge Dip. di Fisica Università degli Studi di Roma 'Tor Vergata' via della Ricerca Scientifica 1 I-00133 Roma Italy INFN - Sezione di Roma 'Tor Vergata' via della Ricerca Scientifica 1 I-00133 Roma Italy Dip. di Fisica e Astronomia Università di Catania via Santa Sofia 44 I-95123 Catania Italy INFN - Sezione di Catania via Santa Sofia 44 I-95123 Catania Italy LPSC Universit Joseph Fourier Grenoble 1 CNRS/IN2P3 Institut National Polytechnique de Grenoble 53 Avenue des Martyres 38026 Grenoble France IPNO Universit de Paris-Sud 11 CNRS/IN2P3 15 rue Georges Clemenceau 91406 Orsay France Dip. di Fisica Sperimentale Università di Torino via P.Giuria I-00125 Torino Italy INFN - Sezione di Torino via P.Giuria I-00125 Torino Italy Istituto Superiore di Sanità viale Regina Elena 299 I-00161 Roma Italy INFN - Sezione di Roma piazzale Aldo Moro 2 I-00185 Roma Italy Dip. di Fisica Universitàdi Messina salita Sperone 31 I-98166 Messina Italy Institute for Nuclear Research RAS 117312 Moscow Russia INFN - Laboratori Nazionali di Frascati via E.Fermi 40 I-00044 Frascati Italy INFN - Sezione di Catania via Santa Sofia 44 I-95123 Catania Italy

The GRAAL experimental set-up consists of a polarized and tagged photon beam that covers an energy range from a minimum of 600 meV up to a maximum of 1500 meV, of a liquid Hydrogen or Deuterium target and of the 4π Lagrange detector optimized for photon detection. It allows the study of pseudo-scalar and vector meson photoproduCtion on the nucleon in the energy range corresponding to the second and the third resonance regions. In the following, the ∑ beam asymmetries in η and π0 photoproduction on quasi-free nucleon are shown. Also single and double polarization observables in K＋A photoproduction on free proton are shown; they are important to confirm the role of new or poorly known resonances in the 1900 meV mass region.

关键词： polarized photon meson photoproduction polarization observables

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盆底功能障碍的mRI—欧洲泌尿生殖放射学会(ESUR)和欧洲胃肠道与腹部放射学会(ESGAR)盆底工作组的联合推荐

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国际医学放射学杂志 2017年第4期 484-485页

作者： R.F.El Sayed C.D.Alt F.maccioni m.meissnitzer G.masselli L.manganaro 朱珍 Genitourinary & Pelvic Floor mR Imaging Unit Department of Radiology Faculty of Medicine Cairo University Hospitals

摘要目的为建立有关盆底功能障碍(PFD)mRI诊断和分级的适应证、病人准备、序列采集、解释和报告的标准化指南提供建议。方法包括1993—2013年之间的评述文献以及由1个埃及和7个欧洲机构组成的ESUR和ESGAR盆底成像工作组制定的mRI专家共...

摘要目的为建立有关盆底功能障碍(PFD)mRI诊断和分级的适应证、病人准备、序列采集、解释和报告的标准化指南提供建议。方法包括1993—2013年之间的评述文献以及由1个埃及和7个欧洲机构组成的ESUR和ESGAR盆底成像工作组制定的mRI专家共识的相关协议。数据收集和分析由5个连续的步骤获得。对82项可进一步分析和排列的项目进行评分。至少80%同意才认为是一致的发现。结果

关键词：

动态增强和DWI评估在物理查体阴性的睾丸小实体肿瘤中的应用

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国际医学放射学杂志 2018年第2期 244-244页

作者： L.manganaro m.Saldari C.Pozza V.Vinci D.Gianfrilli E.Greco 孙成凤 Department of Department of Radiological Oncological and Anatomo -Pathological Sciences La Sapienza University of Rome

摘要目的探讨动态增强mRI(DCE-mRI)半定量和定量参数以及扩散加权成像(DWI)在鉴别物理查体阴性的较小睾丸实体肿瘤良恶性的价值。方法计算了47个较小和未

关键词：动态增强 DWI 实体肿瘤

欧洲泌尿生殖协会的盆腔子宫内膜异位症mR成像(ESUR)指南

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国际医学放射学杂志 2017年第5期 604-604页

作者： m.Bazot N.Bharwani C.Huchon K.Kinkel T.m.Cuerra L.manganaro 洪俐超 Department of Radiology Tenon Hospital

摘要子宫内膜异位症是一种常见、病因不明及主要影响育龄女性的妇科疾病。公认的首选影像检查是盆腔超声。然而,对于复杂病例以及制定手术计划时,mRI作为附加检

关键词：泌尿生殖 mR 子宫内膜异位症

运用mR对比增强成像法前瞻性研究睾丸病变:睾丸间质细胞瘤的特点

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国际医学放射学杂志 2016年第1期 98-98页

作者： L.manganaro V.Vinci C.Pozza m.Saldari D.Gianfrilli R.Pofi 顾康康 Department of Radiology Sapienza University of Rome

摘要目的 20%偶然发现的睾丸病变为良性睾丸间质细胞瘤(LCT)。本研究目的为评估在大型前瞻性队列研究中,运用对比增强mRI识别LCT的作用。材料与方法入选的44例病人都至少有一个不能触及的睾丸实质病变,并接受阴囊mRI。病灶边缘、信号强... 详细信息

摘要目的 20%偶然发现的睾丸病变为良性睾丸间质细胞瘤(LCT)。本研究目的为评估在大型前瞻性队列研究中,运用对比增强mRI识别LCT的作用。材料与方法入选的44例病人都至少有一个不能触及的睾丸实质病变,并接受阴囊mRI。病灶边缘、信号强度和内冲或外冲的模式由2名放射科医生进行分析。恶性和良性的mRI特征在不同组的分布频率采用卡方检验或Fisher概率法进行比较。对敏感度、特异度、阳性和阴性预测值和诊断准确度进行统计计算。结果

关键词：对比增强 mRI LCT 阴囊睾丸囊男生殖器 mR 睾丸间质细胞莱第希细胞