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Journal of Semiconductors 2013年第8期34卷 1-7页

作者： m.R.Fadavieslam m.m.bagheri-mohagheghi School of Physics Damghan University

Thin films of tin selenide（Sn_xSe_y） with an atomic ratio of r =[y/x]= 0.5,1 and 1.5 were prepared on a glass substrate at T = 470℃using a spray pyrolysis *** initial materials for the preparation of the thin films were an alcoholic solution consisting of tin chloride（SnCl_4·5H_2O） and selenide acide（H_2SeO_3）.The prepared thin films were characterized by X-ray diffraction（XRD）,scanning electron microscopy,scanning tunneling microscopy,scanning helium ion microscopy,and UV-vis *** photoconductivity and thermoelectric effects of the Sn_xSe_ythin films were then *** Sn_xSe_y thin films had a polycrystalline structure with an almost uniform surface and cluster type *** increasing atomic ratio of r in the films,the optical gap,photosensitivity and Seebeck coefficient were changed from 1.6 to 1.37 eV,0.01 to 0.31 and -26.2 to—42.7 mV/K （at T = 350 K）,*** addition,the XRD patterns indicated intensity peaks in r = 1 that corresponded to the increase in the SnSe and SnSe_2 phases.

关键词： thin film tin selenide spray pyrolysis optical band gap

Effect of deposition conditions on the physical properties of Sn_xS_y thin films prepared by the spray pyrolysis technique

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Journal of Semiconductors 2011年第11期32卷 31-38页

作者： m.R.Fadavieslam N.Shahtahmasebi m.Rezaee-Roknabadi m.m.bagheri-mohagheghi Nanotechnology Research Center Department of PhysicsFaculty of Basic SciencesFerdowsi University of MashhadMashhadIran School of Physics Damghan University

Tin sulfide thin films （Snx Sy） with an atomic ratio of y/x = 0.5 have been deposited on a glass substrate by spray pyrolysis. The effects of deposition parameters, such as spray solution rate （R）, substrate temperature （Ts） and film thickness （t）, on the structural, optical, thermo-electrical and photoconductivity related properties of the films have been studied. The precursor solution was prepared by dissolving tin chloride （SnC14, 5H2O） and thiourea in propanol, and SnxSy thin film was prepared with a mole ratio of y/x = 0.5. The prepared films were characterized by X-ray diffraction （XRD）, scanning electron microscopy （SEm） and UV-vis spectroscopy. It is indicated that the XRD patterns of SnxSy films have amorphous and polycrystalline structures and the size of the grains has been changed from 7 to 16 nm. The optical gap of SnxSy thin films is determined to be about 2.41 to 3.08 eV by a plot of the variation of （αhv）2 versus h v related to the change of deposition conditions. The thermoelectric and photo-conductivity measurement results for the films show that these properties are depend considerably on the deposition parameters.

关键词： thin film tin sulfide spray pyrolysis photoconductivity

The effect of solution concentration on the physical and electrochemical properties of vanadium oxide films deposited by spray pyrolysis

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Journal of Semiconductors 2013年第10期34卷 8-12页

作者： m.mousavi A.Kompany N.Shahtahmasebi m.m.bagheri-mohagheghi Department of Physics Ferdowsi University of MashhadMashhadIran Nanoscience Center Ferdowsi University of MashhadMashhadIran School of Physics Damghan UniversityDamghanIran

Vanadium oxide thin films were prepared on glass substrates by using the spray pyrolysis technique. The effect of solution concentration （0.1 m, 0.2 m and 0.3 m ） on the nanostructural, electrical, optical, and electrochromic properties of deposited films were investigated using X-ray diffraction, scanning electron microscopy, UV-vis spectroscopy, and cyclic volta-metrics. The X-ray diffraction shows that only the sample at 0.1 m has a single fl-V205 phase and the others have mixed phases of vanadium oxide. The lowest sheet resistance was obtained for the samples prepared at 0.3 m solution. It was also found that the optical transparency of the samples changes from 70% to 35% and the optical band gap of the samples was in the range of 2.20 to 2.41 eV, depending on the morality of solution. The cycle voltammogram shows that the sample prepared at 0.3 m has one-step electerochoromic but the other samples have two-step electerochoromic. The results show a correlation between the cycle voltammogram and the physical properties of the films.

关键词： vanadium oxide thin films optical properties cycle voltammogram

Study of structural,electrical and optical properties of vanadium oxide condensed films deposited by spray pyrolysis technique

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Advances in manufacturing 2013年第4期1卷 320-328页

作者： m.mousavi A.Kompany N.Shahtahmasebi m.m.bagheri-mohagheghi Department of Physics Ferdowsi University of Mashhad Nanoscience Center Ferdowsi University of Mashhad School of Physics Damghan University

Vanadium oxides condensed films are prepared on glass substrates, using spray pyrolysis （SP） technique. The effects of substrate temperature, vanadium concentra- tion in initial solution and the solution spray rate on the nano-structural, electrical, and optical properties of depos- ited films were investigated. Characterizations of the sam- ples were performed using X-ray diffraction （XRD）, scanning electron microscopy （SEm）, and UV-Vis spec- troscopy methods. The type and concentration of the charge carriers were determined and measured by Hall effect experiment. XRD patterns showed that the prepared films had polycrystalline structure, mostly tetragonal fl-V205 and V409 phases with the preferred orientation along （200） direction. The Hall effect experiment revealed that all samples were n-type, except the ones deposited at substrate temperatures Tsub ： 300 ~C and Tsub = 450 ~C, vanadium concentration 0.1 mol/L and solution spray rate 10 mL/min. The charge carrier concentrations obtained were in the range 1016-1018 cm-3. The lowest sheet resistance （R~） was obtained for the samples prepared at T^ub = 450 ~C, vana- dium concentration 0.05 mol/L and solution spray rate 10 mL/min. It was also found that the optical transparency of the samples changed from 20% to 75% and the optical bandgap of the samples was from 2.22 eV to 2.58 eV, depending on the deposition conditions.

关键词： Vanadium oxide Thin films Opticalproperties Spray pyrolysis

Comparison of sol-gel and co-precipitation methods on the structural properties and phase transformation of γ and α-Al2O3 nanoparticles

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Advances in manufacturing 2013年第2期1卷 176-182页

作者： A. Rajaeiyan m. m. bagheri-mohagheghi School of Physics Damghan University Damghan Iran

The nanostructured γ and α alumina powders were synthesized by sol-gel and co-precipitation methods, and properties of the powders were studied by XRD, SEm, TEm, BET and FTIR. The results showed that both γ and α phases were formed in the lower temperature in precipi- tation method compared to sol-gel. The size of spherical α- alumina synthesized by sol-gel was 10-15 nm, whereas the sample prepared by co-precipitation yielded nearly spher- ical and hexagon e-powder with particle size of 10-50 nm. At 750 ℃ the resulting powder prepared by co-precipita- tion exhibited larger surface area （206.2 m2/g） compared to sol-gel （30.72 m2/g）, hence it is recommended for catalytic and sensing applications.

关键词： γ and α-Al2O3 Co-precipitation sol-gel Nanoparticles

Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

SBL-JP-0004:A promising dual inhibitor of JAK2 and PI3KCD against gastric cancer

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Oncology Research 2025年第1期33卷 235-243页

作者： HASSAN m.OTIFI Department of Pathology College of MedicineKing Khalid UniversityAbha62521Saudi Arabia

Background:Gastric cancer(GC)remains a global health burden and is often characterized by heterogeneous molecular profiles and resistance to conventional *** phosphoinositide 3-kinase and PI3K and Janus kinase(JAK)signal transducer and activator of transcription(JAK-STAT)pathways play pivotal roles in GC progression,making them attractive targets for therapeutic ***:This study applied a computational and molecular dynamics simulation approach to identify and characterize SBL-JP-0004 as a potential dual inhibitor of JAK2 and PI3KCD *** and SNU-5 GC cells were used for in vitro ***:SBL-JP-0004 exhibited a robust binding affinity for JAK2 and PI3KCD kinases,as evidenced by molecular docking scores and molecular dynamics *** interactions and Gibbs binding free energy estimates confirmed stable and favorable interactions with target ***-JP-0004 displayed an half-maximal inhibitory concentration(IC_(50))value of 118.9 nm against JAK2 kinase and 200.9 nm against PI3KCD ***-JP-0004 exhibited potent inhibition of cell proliferation in KATOIII and SNU-5 cells,with half-maximal growth inhibitory concentration(GI50)values of 250.8 and 516.3 nm,respectively.A significant elevation in the early phase apoptosis(28.53%in KATOIII cells and 26.85%in SNU-5 cells)and late phase apoptosis(17.37%in KATOIII cells and 10.05%in SNU-5 cells)were observed with SBL-JP-0004 treatment compared to 2.1%and 2.83%in their respective ***:The results highlight SBL-JP-0004 as a promising dual inhibitor targeting JAK2 and PI3KCD kinases for treating GC and warrant further preclinical and clinical investigations to validate its utility in clinical settings.

关键词： Gastric cancer(GC) Dual inhibition JAK2 PI3KCD SBL-JP-0004 molecular docking molecular dynamics simulation

mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología molecular Severo Ochoa(CBm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson’s disease

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Neural Regeneration Research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira m.Holmström Henri J.Huttunen Herantis Pharma Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A major unmet need in the field of central nervous system diseases is disease-modifying *** for decades there have been various symptomatic treatments available to alleviate the symptoms of the disease,disease-modification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatment therapeutic

Search for microglia-specific peptides:advances in the discovery toolbox

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Neural Regeneration Research 2025年第2期20卷 471-472页

作者： Ivan Sarabia Kyle m.Koss Department of Surgery University of ArizonaTucsonAZUSA

Uncontrolled and chronic inflammatory states in the central nervous system(CNS)are the hallmark of neurodegenerative pathology and every injury or stroke-related *** key mediators of these neuroinflammatory states are glial cells known as microglia,the resident immune cell at the core of the inflammatory event,and astroglia,which encapsulate inflammatory insults in proteoglycan-rich scar *** gliotic scar blocks significant portions of healthy axonal networking,preventing *** most neuroinflammation is exclusively based on the responses of said microglia,their phenotypes are suggested to follow those of macrophages;m1 and m2 are opposites of pro-and ***,microglial phenotypes have been identified to be on an inflammatory spectrum encompassing developmental,homeostatic,and reparative behaviors as opposed to their ability to affect devastating cell death cascades and scar tissue formation.

关键词： inflammation pathology death